Mx scripts library: structural equation modeling scripts for twin and family data.

Abstract:

:Structural equation modeling (SEM) provides a flexible tool to carry out genetic analyses of family and twin data. The basic model which decomposes the variance between and within families for a particular trait into genetic and non-genetic components can be generalized to multivariate and/or longitudinal data, incorporate sex differences in parameter estimates, and model the effects of measured environment, candidate genes or DNA marker data. We introduce a web-based library (http://www.psy.vu.nl/mxbib) of scripts for uni- and multivariate genetic epidemiological analyses, as well as for linkage and genetic association tests. The scripts are written to be used with the freely available software package Mx and provide a flexible and uniform approach to the analysis of data from relatives.

journal_name

Behav Genet

journal_title

Behavior genetics

authors

Posthuma D,Boomsma DI

doi

10.1007/s10519-005-2791-5

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

499-505

issue

4

eissn

0001-8244

issn

1573-3297

journal_volume

35

pub_type

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