Relationship between brain and cognitive processes in Down syndrome.

abstract：:Previous animal studies have revealed significant involvement of genetics in nicotine intake; however, the extent of the genetic contribution to this behavior has not been well addressed. We report the first study of nine generations of selection for high and low voluntary nicotine intake in outbred Sprague-Dawley rat...

journal_title：Behavior genetics

authors： Nesil T,Kanit L,Li MD,Pogun S

更新日期：2013-09-01 00:00:00

abstract：:A go/no-go operant task was used to assess the ability of male Long-Evans rats to discriminate between the urine odors from pairs of intact MHC congenic mice (C57BL/6-H-2Kb/J and C57BL/6-H-2Kbm1/ByJ), intact Y congenic mice (DBA1 and DBA1.C57BL10-Y), and castrated Y congenic mice of these two strains. The MHC congenic...

journal_title：Behavior genetics

authors： Schellinck HM,Monahan E,Brown RE,Maxson SC

更新日期：1993-05-01 00:00:00

abstract：:The behaviors of male mice of the C57BL/6J (C57), CBA/Lac (CBA) and BALB/c (BALB) strains have been studied in the plus-maze and open field tests for estimation of state anxiety in the stressful novel conditions, and in the cubic box test (exploration of novel cubic box) and the partition test (behavioral reactivity t...

journal_title：Behavior genetics

authors： Avgustinovich DF,Lipina TV,Bondar NP,Alekseyenko OV,Kudryavtseva NN

更新日期：2000-03-01 00:00:00

abstract：:A model of handedness incorporating both genetic and cultural processes is proposed, based on an evolutionary analysis, and maximum-likelihood estimates of its parameters are generated. This model has the characteristics that (i) no genetic variation underlies variation in handedness, and (ii) variation in handedness ...

journal_title：Behavior genetics

authors： Laland KN,Kumm J,Van Horn JD,Feldman MW

更新日期：1995-09-01 00:00:00

abstract：:The escape efficiency of two closely related species of frogs, Odontophrynus cultripes (2n = 22) and the tetraploid O. americanus (4n = 44), were compared in a shuttle box and under simulated naturalistic conditions. O. americanus was generally superior to O. cultripes, and females tended to outperform males within bo...

journal_title：Behavior genetics

authors： Murphey RM,Beçak W,Dias de Moraes AE

更新日期：1981-05-01 00:00:00

abstract：:There is considerable evidence that sex differences in spatial ability exist in adults, with males outperforming females at every age after puberty. It is difficult, however, to find sex differences in children younger than 13. This is due in part to the lack of adequate measures of spatial ability for use with childr...

journal_title：Behavior genetics

authors： Kerns KA,Berenbaum SA

更新日期：1991-07-01 00:00:00

abstract：:Genome wide complex trait analysis (GCTA) is extended to include environmental effects of the maternal genotype on offspring phenotype ("maternal effects", M-GCTA). The model includes parameters for the direct effects of the offspring genotype, maternal effects and the covariance between direct and maternal effects. A...

journal_title：Behavior genetics

authors： Eaves LJ,Pourcain BS,Smith GD,York TP,Evans DM

更新日期：2014-09-01 00:00:00

abstract：:Six strains of the cosmopolitan species D. immigrans from the Australian life zone plus one from the USA, show weak sexual isolation and more rarely sexual selection. Levels of sexual isolation cannot be related to geographic distances. Assortative mating may have evolved as a byproduct of ecological divergence. ...

journal_title：Behavior genetics

authors： Ehrman L,Parsons PA

更新日期：1980-07-01 00:00:00

abstract：:The paradise fish, a small insectivore, coinhabits marshes of Southeast Asia with several predator fish species. Its ability to recognize and avoid harmful fish may depend upon both genetic factors and experience. Here we demonstrate genetic variability between the 20-day-old larvae of two inbred strains of paradise f...

journal_title：Behavior genetics

authors： Miklósi A,Csányi V,Gerlai R

更新日期：1997-05-01 00:00:00

abstract：:The transmission of social attitudes has been investigated as a possible model of cultural inheritance in a sample of 3810 twin pairs from the Australian National Health and Medical Research Twin Registry. Six social attitude factors were identified and univariate genetic models fitted to scores on each factor. A join...

journal_title：Behavior genetics

authors： Truett KR,Eaves LJ,Meyer JM,Heath AC,Martin NG

更新日期：1992-01-01 00:00:00

abstract：:We report analyses of data on body fat from a cohort of 34 separated monozygotic twin pairs (MZA) and a matched sample of 38 pairs of monozygotic twins reared together (MZT) originally studied by James Shields. The correlation for MZA pairs was .61 and the correlation for MZT pairs was .75. These correlations did not ...

journal_title：Behavior genetics

authors： Price RA,Gottesman II

更新日期：1991-01-01 00:00:00

abstract：:A complimentary two-phase strategy was used to detect and map quantitative trait loci (QTLs) associated with the basal locomotor response to a saline challenge (10 ml/kg). In phase 1, putative QTLs, significant at p < 0.01 or better, were identified by analysis of the strain means for 25 strains of the B x D recombina...

journal_title：Behavior genetics

authors： Koyner J,Demarest K,McCaughran J Jr,Cipp L,Hitzemann R

更新日期：2000-05-01 00:00:00

abstract：:For many psychiatric conditions it is speculated that, rather than being single disease entities, they are a set of several disorders sharing clinical features but having (partly) different underlying causes. The possibility of measuring genetic variation on a large scale has given researchers new hope of identifying ...

journal_title：Behavior genetics

authors： van den Oord E,McClay J,York T,Murrelle L,Robles J

更新日期：2007-05-01 00:00:00

abstract：:In this study we examined cross-sectional age differences in means, phenotypic covariance structure, and the underlying genetic and environmental structure of four personality constructs from Cloninger's personality system: Novelty Seeking (NS), Harm Avoidance (HA), Reward Dependence (RD), and Persistence (PS). Study ...

journal_title：Behavior genetics

authors： Heiman N,Stallings MC,Hofer SM,Hewitt JK

更新日期：2003-03-01 00:00:00

abstract：:Anxiety disorders are phenotypically complex and may involve multiple genetic influences on many neurotransmitter systems. Rodent tests used to investigate genetic influences on anxiety-like phenotypes have face and predictive validity as models for anxiety in humans. If multiple genes contribute additively to a trait...

journal_title：Behavior genetics

authors： Conti LH,Jirout M,Breen L,Vanella JJ,Schork NJ,Printz MP

更新日期：2004-01-01 00:00:00

abstract：:Offspring outcomes are a function of maternal genetics operating on the intrauterine and postnatal environment, offspring genetics and environmental factors. Partitioning genetic effects into maternal and offspring components requires genotyped mother-offspring pairs or genotyped individuals with phenotypic informatio...

journal_title：Behavior genetics

authors： Moen GH,Hemani G,Warrington NM,Evans DM

更新日期：2019-05-01 00:00:00

abstract：:This study documented the etiology contributions between anxiety symptoms (AS) and depressive symptoms (DS) from ages 6-12 years. Teachers assessed AS and DS in 1112 twins at 5 time points. A genetic cross-lagged model was used to estimate genetic/environmental contributions to cross-sectional, cross-age and cross-lag...

journal_title：Behavior genetics

authors： Tanguay-Garneau L,Boivin M,Feng B,Matte-Landry A,Brendgen M,Vitaro F,Dionne G

更新日期：2020-03-01 00:00:00

abstract：:In a sample of 1,940 Dutch 7-year-old twin pairs we studied the etiology of individual differences in Internalizing and Externalizing behavioral problems. For the majority of twins in the sample, both maternal and paternal ratings of behavioral problems were obtained from the Child Behavior Checklist. This made it pos...

journal_title：Behavior genetics

authors： van der Valk JC,van den Oord EJ,Verhulst FC,Boomsma DI

更新日期：2003-07-01 00:00:00

abstract：:Age-related changes are analyzed in the correlation of 3416 monozygotic and 3780 dizygotic U.S. twin pairs aged between 9 and 75+ years for conservatism scores derived from a 28-item social attitude inventory. The effects of the shared environment are overwhelming in twins aged 20 years or younger. In older twins, gen...

journal_title：Behavior genetics

authors： Eaves L,Martin N,Heath A,Schieken R,Meyer J,Silberg J,Neale M,Corey L

更新日期：1997-03-01 00:00:00

abstract：:Knowledge about the proportion of markers without effects (p( 0 )) and the effect sizes in large scale genetic studies is important to understand the basic properties of the data and for applications such as the control of false discoveries and designing adequately powered replication studies. Many p(0) estimators hav...

journal_title：Behavior genetics

authors： Bukszár J,van den Oord EJ

更新日期：2010-05-01 00:00:00

abstract：:As a test of whether sex differences in cognitive functioning are determined by chromosomal constitution or hormonal events, eight subjects whose phenotypic sex differed from their genotypic sex were given a standard intelligence test. The results indicated that differences between verbal and nonverbal abilities corre...

journal_title：Behavior genetics

authors： Rovet J,Netley C

更新日期：1979-07-01 00:00:00

abstract：:Previous studies suggest that brain opioid activity decreases aggression in animal models. The main objective of the current study was to examine the possible genetic relationship between intermale aggression and brain levels of enkephalins, endorphins, and dynorphins in 11 inbred strains of mice. Pursuit, rattling, a...

journal_title：Behavior genetics

authors： Tordjman S,Carlier M,Cohen D,Cesselin F,Bourgoin S,Colas-Linhart N,Petiet A,Perez-Diaz F,Hamon M,Roubertoux PL

更新日期：2003-09-01 00:00:00

abstract：:Gender-moderated gene-environment interactions are rarely explored, raising concerns about inaccurate specification of etiological models and inferential errors. The current study examined the influence of gender, negative and positive daily life events, and GABRA2 genotype (SNP rs279871) on alcohol dependence, testin...

journal_title：Behavior genetics

authors： Perry BL,Pescosolido BA,Bucholz K,Edenberg H,Kramer J,Kuperman S,Schuckit MA,Nurnberger JI Jr

更新日期：2013-09-01 00:00:00

abstract：:Complex illnesses, like depression, are thought to arise from the interplay between psychosocial stressors and genetic predispositions. Approaches that take into account both personal and neighborhood factors and that consider gene regions as well as individual SNPs may be necessary to capture these interactions acros...

journal_title：Behavior genetics

authors： Ware EB,Smith JA,Mukherjee B,Lee S,Kardia SL,Diez-Roux AV

更新日期：2016-01-01 00:00:00

abstract：:Genetic and environmental influences in the determination of individual differences in self-reported symptoms of separation anxiety (SAD), overanxious disorder (OAD), and manifest anxiety (MANX) were evaluated in children and adolescents for three age groups (8-10, 11-13, and 14-16). Symptom counts for SAD and OAD wer...

journal_title：Behavior genetics

authors： Topolski TD,Hewitt JK,Eaves LJ,Silberg JL,Meyer JM,Rutter M,Pickles A,Simonoff E

更新日期：1997-01-01 00:00:00

abstract：:The ε4 allele of the apolipoprotein (APOE) gene is a widely recognized genetic risk factor for developing Alzheimer's disease in older age. However, it is controversial whether there is a positive impact of the APOE ε4 allele on human cognitive performance in young adulthood, possibly representing a case of antagonist...

journal_title：Behavior genetics

authors： Li X,Hildebrandt A,Sommer W,Wilhelm O,Reuter M,Montag C,Zhou C

更新日期：2019-09-01 00:00:00

abstract：:We present a repeated-measures, genetic analysis of ethanol-induced anesthesia (sleep time) in mice from the inbred long-sleep (ILS) and short-sleep (ISS) strains of mice and their derived F1 and F2 generations. Mice (total N > 1300) were administered a 4.1 g/kg intraperitoneal dose of ethanol at two times, 7 to 10 da...

journal_title：Behavior genetics

authors： Markel PD,DeFries JC,Johnson TE

更新日期：1995-01-01 00:00:00

abstract：:Our genetic knowledge of a species is reflected in the state of its gene map. Although still primitive, relative to the gene map of the mouse, great strides have been made in recent years in developing the gene map of the rat and nine linkage groups have now been defined. Mapping by conventional backcrossing methods h...

journal_title：Behavior genetics

authors： Womack JE

更新日期：1981-09-01 00:00:00

abstract：:It has been hypothesized that numerous genes contribute to individual variation in human cognition. An extensive search of the scientific literature was undertaken to identify candidate genes which might contribute to this complex trait. A list of over 150 candidate genes that may influence some aspect of cognition wa...

journal_title：Behavior genetics

authors： Morley KI,Montgomery GW

更新日期：2001-11-01 00:00:00

abstract：:Based on the reviewed literature and the data presented in this paper, conclusions can be drawn with respect to the validity of the WAG/Rij strain of rats as a model for absence epilepsy in humans. The view that the WAG/Rij model has "face validity" is supported by the simultaneous presence of clinical and electroence...

journal_title：Behavior genetics

authors： Coenen AM,Van Luijtelaar EL

更新日期：2003-11-01 00:00:00