Identification of quantitative trait Loci for anxiety and locomotion phenotypes in rat recombinant inbred strains.

abstract：:In this article, we successfully apply the novel model selection method, Bayesian composite model space approach which has been used to map quantitative trait loci (QTL) for allelic substitution model, to map QTL for variance component model. The novel model selection approach has two advantages compared to the revers...

journal_title：Behavior genetics

authors： Fang M,Liu S,Jiang D

更新日期：2009-05-01 00:00:00

abstract：:Two separate genome-wide association studies were conducted to identify single nucleotide polymorphisms (SNPs) associated with social and nonsocial autistic-like traits. We predicted that we would find SNPs associated with social and non-social autistic-like traits and that different SNPs would be associated with soci...

journal_title：Behavior genetics

authors： Ronald A,Butcher LM,Docherty S,Davis OS,Schalkwyk LC,Craig IW,Plomin R

更新日期：2010-01-01 00:00:00

abstract：:Callous-unemotional (CU) traits comprise the core symptoms of psychopathy, yet no study has estimated the heritability of CU traits in a community sample of children using an instrument designed solely to assess CU traits. The current study uses data from 339 twin pairs aged 9-14 to examine the reliability and heritab...

journal_title：Behavior genetics

authors： Moore AA,Carney D,Moroney E,Machlin L,Towbin KE,Brotman MA,Pine DS,Leibenluft E,Roberson-Nay R,Hettema JM

更新日期：2017-03-01 00:00:00

abstract：:Mating behavior, including courtship and copulation, is a main component of male fitness, especially in species with no parental care. Variation in this behavior can thus be a target for mate choice and sexual selection, and can lead to evolution. The fruit fly, Drosophila melanogaster, has well-documented complex mal...

journal_title：Behavior genetics

authors： Ruedi EA,Hughes KA

更新日期：2008-07-01 00:00:00

abstract：:Chronic pelvic pain (CPP) is a common condition in women that is difficult to diagnose. Although heritability estimates have been published for some conditions potentially underlying pelvic pain, the heritability of CPP itself has never been investigated. Using data from 623 MZ and 377 DZ female twin pairs aged 29-50 ...

journal_title：Behavior genetics

authors： Zondervan KT,Cardon LR,Kennedy SH,Martin NG,Treloar SA

更新日期：2005-03-01 00:00:00

abstract：:Our genetic knowledge of a species is reflected in the state of its gene map. Although still primitive, relative to the gene map of the mouse, great strides have been made in recent years in developing the gene map of the rat and nine linkage groups have now been defined. Mapping by conventional backcrossing methods h...

journal_title：Behavior genetics

authors： Womack JE

更新日期：1981-09-01 00:00:00

abstract：:Martin and Wilson (1982) describe two forms of sampling bias in twin studies. One is "hard selection," where individuals above a threshold participate, and those below do not. The second is "soft selection," where the probability of including a pair of relatives varies over the range of the character. We present an al...

journal_title：Behavior genetics

authors： Neale MC,Eaves LJ,Kendler KS,Hewitt JK

更新日期：1989-03-01 00:00:00

abstract：:The most common alternative to a genetic explanation of left-handedness is that sinistrality arises because of birth stress factors. In a sample of 1398 subjects, the association between birth stress and left-handedness was confirmed. More importantly, it was found that left-handed mothers are more likely to have birt...

journal_title：Behavior genetics

authors： Coren S

更新日期：1995-11-01 00:00:00

abstract：:Based on the reviewed literature and the data presented in this paper, conclusions can be drawn with respect to the validity of the WAG/Rij strain of rats as a model for absence epilepsy in humans. The view that the WAG/Rij model has "face validity" is supported by the simultaneous presence of clinical and electroence...

journal_title：Behavior genetics

authors： Coenen AM,Van Luijtelaar EL

更新日期：2003-11-01 00:00:00

abstract：:Genes involved in melatonin synthesis, such as Aa-nat, may be important for our understanding of diurnal preference and circadian rhythm disturbances in humans. In Japan, Hohjoh et al. reported increased allelic frequencies of the 619A allele of the G619A Aa-nat gene polymorphism in a sample of Delayed Sleep Phase Syn...

journal_title：Behavior genetics

authors： Pereira DS,Pedrazzoli M,Koike Bdel V,Louzada FM,Benedito-Silva AA,Lopez AR,Tufik S

更新日期：2007-07-01 00:00:00

abstract：:Gender-moderated gene-environment interactions are rarely explored, raising concerns about inaccurate specification of etiological models and inferential errors. The current study examined the influence of gender, negative and positive daily life events, and GABRA2 genotype (SNP rs279871) on alcohol dependence, testin...

journal_title：Behavior genetics

authors： Perry BL,Pescosolido BA,Bucholz K,Edenberg H,Kramer J,Kuperman S,Schuckit MA,Nurnberger JI Jr

更新日期：2013-09-01 00:00:00

abstract：:In the course of the East Flanders Prospective Twin Survey (EFPTS), handedness was assessed as part of a genealogical study (Meulemans et al., 1995) in 1616 twins (808 twin pairs) aged 6 to 28. Our findings are that, in this large population-based study with known placentation and zygosity, the often observed higher f...

journal_title：Behavior genetics

authors： Derom C,Thiery E,Vlietinck R,Loos R,Derom R

更新日期：1996-07-01 00:00:00

abstract：:The initial experimental population of Drosophila persimilis was photopositive and slightly geonegative. In this respect, the initial population of D. persimilis differed from the experimental population of D. pseudoobscura, described by others, which was close to photo- and geotactic neutrality. In D. persimilis as i...

journal_title：Behavior genetics

authors： Polivanov S

更新日期：1975-07-01 00:00:00

abstract：:Parameters of quantitative genetic models have traditionally been estimated by either algebraic manipulation of familial correlations (or familial mean squares), biometric model fitting, or multiple-group covariance structure analysis. With few exceptions, researchers who have used these methods for the analysis of tw...

journal_title：Behavior genetics

authors： Waller NG,Muthén BO

更新日期：1992-05-01 00:00:00

abstract：:Individuals involved in a social interaction exhibit different behavioral traits that, in combination, form the individual's behavioral responses. Selectively bred strains of silver foxes (Vulpes vulpes) demonstrate markedly different behaviors in their response to humans. To identify the genetic basis of these behavi...

journal_title：Behavior genetics

authors： Nelson RM,Temnykh SV,Johnson JL,Kharlamova AV,Vladimirova AV,Gulevich RG,Shepeleva DV,Oskina IN,Acland GM,Rönnegård L,Trut LN,Carlborg Ö,Kukekova AV

更新日期：2017-01-01 00:00:00

abstract：:Genetic and environmental influences on problem behaviors were studied in a sample of international adoptees. Parental ratings of childrens' problem behaviors were obtained with the Child Behavior Checklist (CBCL). The sample (mean age, 12.4 years) comprised a group of biological siblings (111 pairs), a group of nonbi...

journal_title：Behavior genetics

authors： van den Oord EJ,Boomsma DI,Verhulst FC

更新日期：1994-05-01 00:00:00

abstract：:A large sample of adult twins (1117 pairs), who were concordant for having had children were asked to report on their child-rearing practices. A 14-item version of the Parental Bonding Instrument (PBI) was used to assess rearing practices of parent twins. The two factors of Care and Overprotection, commonly found in o...

journal_title：Behavior genetics

authors： Pérusse D,Neale MC,Heath AC,Eaves LJ

更新日期：1994-07-01 00:00:00

abstract：:The amygdala integrates and coordinates emotional and autonomic responses. The genetics that underlie variation in amygdala structure may be coupled to variation in levels of aggression, fear, anxiety, and affiliated behaviors. We systematically quantified the volume and cell populations of the basolateral amygdala co...

journal_title：Behavior genetics

authors： Mozhui K,Hamre KM,Holmes A,Lu L,Williams RW

更新日期：2007-01-01 00:00:00

abstract：:Alterations of peripheral magnesium (Mg) concentration have been reported in association with several behavioral disorders and sleep organization. Blood Mg regulation is under a strong genetic control, whereas brain Mg regulation does not seem to be affected. We have studied peripheral and central levels of Mg and ana...

journal_title：Behavior genetics

authors： Chollet D,Franken P,Raffin Y,Henrotte JG,Widmer J,Malafosse A,Tafti M

更新日期：2001-09-01 00:00:00

abstract：:Male Drosophila melanogaster from lines artificially selected to have divergent life histories were tested to determine if they differed in their effects on female reproductive behavior. During the first 5 days after mating, males from short-generation populations caused females to lay eggs at a faster rate than did m...

journal_title：Behavior genetics

authors： Service PM,Vossbrink RE

更新日期：1996-01-01 00:00:00

abstract：:Latent variable models are used in biological and social sciences to investigate characteristics that are not directly measurable. The generation of individual scores of latent variables can simplify subsequent analyses. However, missing measurements in real data complicate the calculation of scores. Missing observati...

journal_title：Behavior genetics

authors： Campbell DD,Rijsdijk FV,Sham PC

更新日期：2007-03-01 00:00:00

abstract：:Genome wide complex trait analysis (GCTA) is extended to include environmental effects of the maternal genotype on offspring phenotype ("maternal effects", M-GCTA). The model includes parameters for the direct effects of the offspring genotype, maternal effects and the covariance between direct and maternal effects. A...

journal_title：Behavior genetics

authors： Eaves LJ,Pourcain BS,Smith GD,York TP,Evans DM

更新日期：2014-09-01 00:00:00

abstract：:Data from two twin studies were used to address two related questions. First, is there any association between handedness and specific speech and language impairment (SSLI) in children? Second, is there genetic influence on individual differences in handedness and, if so, are the same genes implicated in the cause of ...

journal_title：Behavior genetics

authors： Bishop DV

更新日期：2001-07-01 00:00:00

abstract：:Twin studies are useful for assessing the relative importance of genetic or heritable component from the environmental component. In this paper we develop a methodology to study the heritability of age-at-onset or lifespan traits, with application to analysis of twin survival data. Due to limited period of observation...

journal_title：Behavior genetics

authors： Ha ID,Lee Y,Pawitan Y

更新日期：2007-07-01 00:00:00

abstract：:Elucidating the causes of population divergence, and ultimately speciation, is a central objective of evolutionary biology. A number of previous studies of Drosophila populations from the Nahal Oren canyon (Mt Carmel, Israel) revealed significant interslope differences for a complex of fitness and behavioral traits. P...

journal_title：Behavior genetics

authors： Singh SR,Rashkovetsky E,Iliadi K,Nevo E,Korol A

更新日期：2005-11-01 00:00:00

abstract：:In this study we examined cross-sectional age differences in means, phenotypic covariance structure, and the underlying genetic and environmental structure of four personality constructs from Cloninger's personality system: Novelty Seeking (NS), Harm Avoidance (HA), Reward Dependence (RD), and Persistence (PS). Study ...

journal_title：Behavior genetics

authors： Heiman N,Stallings MC,Hofer SM,Hewitt JK

更新日期：2003-03-01 00:00:00

abstract：:Genomewide scan, as shown by recently published linkage studies on the behavior of mice or in psychiatry, provides evidence for replicated quantitative trait loci (QTL). Several studies of Alzheimer's disease have demonstrated the promise of moving from clinical diagnoses to biological signs for psychiatric investigat...

journal_title：Behavior genetics

authors： Roubertoux PL,Le Roy-Duflos I

更新日期：2001-01-01 00:00:00

abstract：:It has been hypothesized that numerous genes contribute to individual variation in human cognition. An extensive search of the scientific literature was undertaken to identify candidate genes which might contribute to this complex trait. A list of over 150 candidate genes that may influence some aspect of cognition wa...

journal_title：Behavior genetics

authors： Morley KI,Montgomery GW

更新日期：2001-11-01 00:00:00

abstract：:Chickens homozygous for the Dominant white or wild-type allele of PMEL17 were subjected to a broad phenotyping in order to detect consistent differences between genotypes. To exclude feather pecking, the chickens were individually housed without physical contact, from the day of hatching, and tested for social, aggres...

journal_title：Behavior genetics

authors： Karlsson AC,Mormede P,Kerje S,Jensen P

更新日期：2011-03-01 00:00:00

abstract：:The Inositol 1,4,5-triphosphate (IP3) route is one of the two main transduction cascades that mediate olfactory reception in Drosophila melanogaster. The activity of IP3 kinase1 reduces the levels of this substrate by phosphorylation into inositol 1,3,4,5-tetrakiphosphate (IP4). We show here that the gene is expressed...

journal_title：Behavior genetics

authors： Gomez-Diaz C,Martin F,Alcorta E

更新日期：2006-03-01 00:00:00