Abstract:
:Data from two twin studies were used to address two related questions. First, is there any association between handedness and specific speech and language impairment (SSLI) in children? Second, is there genetic influence on individual differences in handedness and, if so, are the same genes implicated in the cause of SSLI? The first study used data from 58 MZ and 26 DZ pairs previously recruited for an investigation into the genetic origins of SSLI. All pairs contained at least one child with SSLI. Handedness was assessed using a preference inventory and a tapping task from which a laterality quotient (LQ) was derived. There were no handedness differences between these twins and 172 singleborn controls, and neither measure revealed any association between handedness and SSLI. The data were equally well-fitted by a CE model (no genetic influence) and an AE model (no effect of shared environment) for both hand preference and tapping LQ. Nonshared environment was the largest influence on handedness for both measures. Bivariate analysis indicated no overlapping genetic influences on SSLI and handedness. In the second study, handedness was assessed in a general population sample of 48 MZ and 44 DZ twin pairs, aged 7 to 13 years, using a preference inventory and a peg-moving task. A subset of children was also given a test that assessed persistence of hand preference when reaching across the midline. The latter was the only measure to relate to children's language status, with language-impaired children showing less midline crossing. This appears to reflect neurodevelopmental immaturity, rather than a stable trait. To investigate familial transmission of handedness, inventory data for parents and their twins were combined for both samples. The most parsimonious model was one that accounted for parent-child resemblance solely in terms of cultural transmission. Overall, there was no evidence that genes play a role in determining stable individual differences in hand preference. Insofar as there are links between handedness and speech and language difficulties, these reflect delayed neuromotor maturation.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Bishop DVdoi
10.1023/a:1012239617367subject
Has Abstractpub_date
2001-07-01 00:00:00pages
339-51issue
4eissn
0001-8244issn
1573-3297journal_volume
31pub_type
杂志文章abstract::A recent controversy has given reason to examine the place of Burt's data among other behavioral genetic data on IQ. Although Burt's kinship correlations are higher than the average of other studies, his results are generally consistent with other data. ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067708
更新日期:1978-01-01 00:00:00
abstract::A central issue in psychiatric genetics is whether positive findings replicate. Zubenko et al. (2002b, Mol. Psychiatry 7:460-467) reported an association of the 124-bp allele of D2S2944 with recurrent early-onset major depression for females. We tested for association of this allele to continuous measures of anxiety, ...
journal_title:Behavior genetics
pub_type: 杂志文章,多中心研究
doi:10.1007/s10519-005-9006-y
更新日期:2006-01-01 00:00:00
abstract::The transmission of social attitudes has been investigated as a possible model of cultural inheritance in a sample of 3810 twin pairs from the Australian National Health and Medical Research Twin Registry. Six social attitude factors were identified and univariate genetic models fitted to scores on each factor. A join...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066792
更新日期:1992-01-01 00:00:00
abstract::Extreme sampling of sibling pairs has been shown to be efficient in terms of statistical power and sample sizes (in number of sibling pairs needed to genotype) to detect a quantitative trait locus (QTL) when the residual distribution is normal. In the present study, the efficiency of extreme sampling strategies to det...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1014403827957
更新日期:2002-01-01 00:00:00
abstract::If appropriately determined, recombinant-inbred (RI) strain means provide an excellent method for determining genetic correlations among complex characters. However, little systematic attention has been paid to important environmental influences on strain means such as random effects due to litter membership or system...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1007/BF01066634
更新日期:1992-11-01 00:00:00
abstract::Bullying comes in different forms, yet most previous genetically-sensitive studies have not distinguished between them. Given the serious consequences and the high prevalence of bullying, it is remarkable that the aetiology of bullying and its different forms has been under-researched. We present the first study to in...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-019-09968-5
更新日期:2019-09-01 00:00:00
abstract::Males from the fifty selected generation of a selection program for aggressiveness in female Mus musculus (Ebert and Hyde, 1976) were tested to determine whether male aggressiveness showed a correlated response in selection for female aggressiveness. The results indicated that male aggression had not shown a correlate...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065699
更新日期:1976-10-01 00:00:00
abstract::Reading difficulties are both heritable and stable; however, little is known about the etiology of this stability. Results from a preliminary analysis of data from 56 twin pairs who participated in the Colorado Longitudinal Twin Study of Reading Disability (Astrom et al., Twin Res Hum Genet 10:434-439, 2007) suggested...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-011-9445-6
更新日期:2011-09-01 00:00:00
abstract::Heterozygous staggerer mice (Rora(+)/Rora(sg)) and control mice (Rora(+)/Rora(+)) of the same C57BL/6J strain background were tested in a spontaneous alternation task at 3 to 24 months old. The results demonstrated a decrement in long-term working memory as early as 6 months in Rora(+)/Rora(+) mice and at 3 months in ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/B:BEGE.0000017875.78571.a6
更新日期:2004-05-01 00:00:00
abstract::In this study we examined cross-sectional age differences in means, phenotypic covariance structure, and the underlying genetic and environmental structure of four personality constructs from Cloninger's personality system: Novelty Seeking (NS), Harm Avoidance (HA), Reward Dependence (RD), and Persistence (PS). Study ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1022558002760
更新日期:2003-03-01 00:00:00
abstract::Behaviors with high energetic costs may decrease in frequency in domestic animals as a response to selection for increased production. The aim of this study was to quantify production traits, foraging behavior, and social motivation in F2 progeny from a White Leghorn x red junglefowl intercross (n = 751-1046) and to p...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1020880211144
更新日期:2002-11-01 00:00:00
abstract::In an investigation into the effects of developmental isolation from all conspecifics, the Drosophila willistoni group of six sibling species responded to differing degrees: all six are reproductively isolated from D. paulistorum, the tester species. Drosophila pavlovskiana, a narrow endemic, proved the most vulnerabl...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1021494023660
更新日期:1999-01-01 00:00:00
abstract::For many psychiatric conditions it is speculated that, rather than being single disease entities, they are a set of several disorders sharing clinical features but having (partly) different underlying causes. The possibility of measuring genetic variation on a large scale has given researchers new hope of identifying ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-006-9135-y
更新日期:2007-05-01 00:00:00
abstract::Previously, sequence variation in the glucocorticoid (GR) and mineralocorticoid (MR) receptor genes (NR3C1 and NR3C2, respectively) have been found to be associated with physiological stress responses to social stress tests in small samples of adult men and oral contraceptives (OC) using women. Associations between si...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-010-9385-6
更新日期:2011-03-01 00:00:00
abstract::Mutations on the period locus of Drosophila melanogaster influence circadian periods as well as the rhythm in inter-pulse intervals in male courtship song; perL mutations produce long circadian periods and courtship song rhythms and per(s) mutations produce short circadian periods and courtship song rhythms. Thus, the...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1021625819967
更新日期:1998-09-01 00:00:00
abstract::Social aggregations of free-ranging cattle were studied in the Sonoran Desert of Mexico. Cows reared with animals of their own breed in isolation from other breeds maintained segregated social groups. Cows raised together in a mixed herd containing other breeds allied themselves with herd-mates regardless of breed. Ca...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065562
更新日期:1990-05-01 00:00:00
abstract::In the course of the East Flanders Prospective Twin Survey (EFPTS), handedness was assessed as part of a genealogical study (Meulemans et al., 1995) in 1616 twins (808 twin pairs) aged 6 to 28. Our findings are that, in this large population-based study with known placentation and zygosity, the often observed higher f...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02359484
更新日期:1996-07-01 00:00:00
abstract::Genes involved in melatonin synthesis, such as Aa-nat, may be important for our understanding of diurnal preference and circadian rhythm disturbances in humans. In Japan, Hohjoh et al. reported increased allelic frequencies of the 619A allele of the G619A Aa-nat gene polymorphism in a sample of Delayed Sleep Phase Syn...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-007-9155-2
更新日期:2007-07-01 00:00:00
abstract::As a test of whether sex differences in cognitive functioning are determined by chromosomal constitution or hormonal events, eight subjects whose phenotypic sex differed from their genotypic sex were given a standard intelligence test. The results indicated that differences between verbal and nonverbal abilities corre...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01068210
更新日期:1979-07-01 00:00:00
abstract::A wealth of literature suggests that normative and heavy alcohol consumption continue to follow a historical pattern of greater prevalence among males as compared to females. Some prior research suggested that sex-specific factors might explain some of this gender gap. Generally speaking, though, more recent studies h...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-020-10004-0
更新日期:2020-09-01 00:00:00
abstract::It has been hypothesized that numerous genes contribute to individual variation in human cognition. An extensive search of the scientific literature was undertaken to identify candidate genes which might contribute to this complex trait. A list of over 150 candidate genes that may influence some aspect of cognition wa...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1023/a:1013337209957
更新日期:2001-11-01 00:00:00
abstract::This paper uses data from the National Longitudinal Study of Adolescent Health to examine the extent to which school-level social and institutional factors moderate genetic tendencies to smoke cigarettes. Our analysis relies on a sub-sample of 1,198 sibling and twin pairs nested within 84 schools. We develop a multile...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-008-9197-0
更新日期:2008-05-01 00:00:00
abstract::A genome-wide linkage scan of 795 microsatellite markers (761 autosomal, 34 X chromosome) was performed on Multidimensional Aptitude Battery subtests and verbal, performance and full scale scores, the WAIS-R Digit Symbol subtest, and two word-recognition tests (Schonell Graded Word Reading Test, Cambridge Contextual R...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-005-9003-1
更新日期:2006-01-01 00:00:00
abstract::The conditioned and reflex parameters in rat lines selected for the threshold of excitability (a fundamental characteristics of the functional state of the nervous system) were estimated. This measure is based on the response of the tibial nerve to electrical stimulation, which gives a general indication of the level ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067986
更新日期:1993-09-01 00:00:00
abstract::The escape efficiency of two closely related species of frogs, Odontophrynus cultripes (2n = 22) and the tetraploid O. americanus (4n = 44), were compared in a shuttle box and under simulated naturalistic conditions. O. americanus was generally superior to O. cultripes, and females tended to outperform males within bo...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065462
更新日期:1981-05-01 00:00:00
abstract::Gonadotropin-releasing hormone (GnRH), having a highly conserved structure across mammalian species, plays a pivotal role in the control of the neuroendocrine events and the inherent sexual behaviors essential for reproductive function. Recent advances in molecular genetic technology have contributed greatly to the in...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1007/BF02359383
更新日期:1996-05-01 00:00:00
abstract::The initial experimental population of Drosophila persimilis was photopositive and slightly geonegative. In this respect, the initial population of D. persimilis differed from the experimental population of D. pseudoobscura, described by others, which was close to photo- and geotactic neutrality. In D. persimilis as i...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066177
更新日期:1975-07-01 00:00:00
abstract::Male Drosophila melanogaster from lines artificially selected to have divergent life histories were tested to determine if they differed in their effects on female reproductive behavior. During the first 5 days after mating, males from short-generation populations caused females to lay eggs at a faster rate than did m...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02361157
更新日期:1996-01-01 00:00:00
abstract::Feather pecking (FP) is a serious economic and welfare problem in the domestic fowl. It has recently been shown that the distribution of FP bouts within groups is heterogeneous and contains a sub-population of extreme feather peckers (EFP). The present study proposed a novel model to detect EFP hens. A mixture of two ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-019-09971-w
更新日期:2020-01-01 00:00:00
abstract::This study uses longitudinal population-based samples of young siblings to examine the effects of two hypothesized moderators of early externalizing behaviors: parental emotional support and family socioeconomic status. The first sample, a twin sample from the Early Childhood Longitudinal Study-Birth Cohort (ECLS-B), ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9664-8
更新日期:2014-09-01 00:00:00