Abstract：
:Reading difficulties are both heritable and stable; however, little is known about the etiology of this stability. Results from a preliminary analysis of data from 56 twin pairs who participated in the Colorado Longitudinal Twin Study of Reading Disability (Astrom et al., Twin Res Hum Genet 10:434-439, 2007) suggested that about two-thirds of the proband deficit at follow-up was due to genetic factors that also influenced deficits at their initial assessment. Although our proband sample is now nearly twice as large, it is still relatively small; thus, to increase power, we subjected data from probands, co-twins and their nontwin siblings to a novel extension of DeFries-Fulker analysis (DeFries and Fulker, Behav Genet 15:467-473, 1985; DeFries and Fulker, Acta Genet Med Gemellol, 37, 205-216, 1988). In addition to providing estimates of univariate and bivariate heritability, this analysis facilitates a test of the difference between shared environmental influences for twins versus siblings. Longitudinal composite reading performance scores at 10.6 and 15.5 years of age, on average, were analyzed from 33 MZ and 64 DZ twin pairs in which at least one member of each pair had reading difficulties, and from 44 siblings of the probands. Scores were highly stable (.86 ± .03, across probands, co-twins and siblings) and heritability of the group deficit at initial assessment was .67 ± .22. Longitudinal bivariate heritability was .59 ± .21, suggesting that nearly 60% of the proband reading deficit at follow-up is due to genetic factors that influenced reading difficulties at the initial assessment. However, tests for special twin environmental influences were nonsignificant.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Astrom RL,Wadsworth SJ,Olson RK,Willcutt EG,DeFries JCdoi
10.1007/s10519-011-9445-6subject
Has Abstractpub_date
2011-09-01 00:00:00pages
660-7issue
5eissn
0001-8244issn
1573-3297journal_volume
41pub_type
杂志文章abstract：:Heterozygous staggerer mice (Rora(+)/Rora(sg)) and control mice (Rora(+)/Rora(+)) of the same C57BL/6J strain background were tested in a spontaneous alternation task at 3 to 24 months old. The results demonstrated a decrement in long-term working memory as early as 6 months in Rora(+)/Rora(+) mice and at 3 months in ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/B:BEGE.0000017875.78571.a6
更新日期：2004-05-01 00:00:00
abstract：:Rhythm of activity of inbred mice was recorded automatically by a set of actographs. This rhythm was characterized by six indices in the temporal and frequency domains. Two methods of genetic analysis were applied to these indices using parental strains BALB/c and C57BL/6, the reciprocal F1's, and the seven recombinan...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01066331
更新日期：1991-03-01 00:00:00
abstract：:Two separate genome-wide association studies were conducted to identify single nucleotide polymorphisms (SNPs) associated with social and nonsocial autistic-like traits. We predicted that we would find SNPs associated with social and non-social autistic-like traits and that different SNPs would be associated with soci...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-009-9308-6
更新日期：2010-01-01 00:00:00
abstract：:In studies of child psychopathology, phenotypes of interest are often obtained by parental ratings. When behavioral ratings are obtained in the context of a twin study, this allows for the decomposition of the phenotypic variance, into a genetic and a non-genetic part. If a phenotype is assessed by a single rater, her...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-016-9823-1
更新日期：2017-03-01 00:00:00
abstract：:In an investigation into the effects of developmental isolation from all conspecifics, the Drosophila willistoni group of six sibling species responded to differing degrees: all six are reproductively isolated from D. paulistorum, the tester species. Drosophila pavlovskiana, a narrow endemic, proved the most vulnerabl...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1021494023660
更新日期：1999-01-01 00:00:00
abstract：:Six strains of the cosmopolitan species D. immigrans from the Australian life zone plus one from the USA, show weak sexual isolation and more rarely sexual selection. Levels of sexual isolation cannot be related to geographic distances. Assortative mating may have evolved as a byproduct of ecological divergence. ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01065601
更新日期：1980-07-01 00:00:00
abstract：:The prevalence of marriage varies across the lifespan, as does its importance to reproduction and the nurturance of children. We examined genetic and environmental influences on self-reported marriage at each decade from 20 through 70 years of age, using data collected for the Duke Dementia Study, a followed-up subset...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-006-9132-1
更新日期：2007-03-01 00:00:00
abstract：:A genome-wide linkage scan of 795 microsatellite markers (761 autosomal, 34 X chromosome) was performed on Multidimensional Aptitude Battery subtests and verbal, performance and full scale scores, the WAIS-R Digit Symbol subtest, and two word-recognition tests (Schonell Graded Word Reading Test, Cambridge Contextual R...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-005-9003-1
更新日期：2006-01-01 00:00:00
abstract：:Courtship song serves as a sexual signal and may contribute to reproductive isolation between closely related species. Using lines of Drosophila pseudoobscura experimentally selected under different sexual selection regimes, we tested whether increased promiscuity and enforced monogamy led to evolutionary changes in c...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-005-3217-0
更新日期：2005-05-01 00:00:00
abstract：:Inhibitory control (IC) is a dimension of child temperament that emerges in toddlerhood and involves the ability to regulate behavior in response to instructions or expectations. In general, children with low levels of IC have more cognitive and social difficulties, and higher levels of problem behaviors. Unfortunatel...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-009-9316-6
更新日期：2010-05-01 00:00:00
abstract：:Genes involved in melatonin synthesis, such as Aa-nat, may be important for our understanding of diurnal preference and circadian rhythm disturbances in humans. In Japan, Hohjoh et al. reported increased allelic frequencies of the 619A allele of the G619A Aa-nat gene polymorphism in a sample of Delayed Sleep Phase Syn...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-007-9155-2
更新日期：2007-07-01 00:00:00
abstract：:We present a repeated-measures, genetic analysis of ethanol-induced anesthesia (sleep time) in mice from the inbred long-sleep (ILS) and short-sleep (ISS) strains of mice and their derived F1 and F2 generations. Mice (total N > 1300) were administered a 4.1 g/kg intraperitoneal dose of ethanol at two times, 7 to 10 da...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF02197243
更新日期：1995-01-01 00:00:00
abstract：:Genetic heritability (h2) of alcohol use is reported to be greater in rural dwellers, distressed marriages, low socioeconomic status, in girls who are unmarried or lacking closeness with their parents or religious upbringing, in less-educated men, and in adolescents with peers using alcohol. However, these are all ris...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-020-10005-z
更新日期：2020-09-01 00:00:00
abstract：:The region containing ROBO1 (Chromosome 3p12.3) has been implicated as a susceptibility gene for reading disorder and language deficit by translocation and linkage data. No association studies have yet been reported supporting any candidate gene. Here we report the first association of this gene with language deficits...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-010-9402-9
更新日期：2011-01-01 00:00:00
abstract：:Male Drosophila melanogaster from lines artificially selected to have divergent life histories were tested to determine if they differed in their effects on female reproductive behavior. During the first 5 days after mating, males from short-generation populations caused females to lay eggs at a faster rate than did m...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF02361157
更新日期：1996-01-01 00:00:00
abstract：:As a test of whether sex differences in cognitive functioning are determined by chromosomal constitution or hormonal events, eight subjects whose phenotypic sex differed from their genotypic sex were given a standard intelligence test. The results indicated that differences between verbal and nonverbal abilities corre...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01068210
更新日期：1979-07-01 00:00:00
abstract：:A wealth of literature suggests that normative and heavy alcohol consumption continue to follow a historical pattern of greater prevalence among males as compared to females. Some prior research suggested that sex-specific factors might explain some of this gender gap. Generally speaking, though, more recent studies h...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-020-10004-0
更新日期：2020-09-01 00:00:00
abstract：:It is well established that many continuously distributed traits have a heritable component. However, it is often difficult to communicate to the general public the meaning of quantitative estimates of heritability. To address this problem, the present paper introduces a heuristic for communicating heritability to non...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1025670316169
更新日期：1997-09-01 00:00:00
abstract：:A powerful longitudinal data source, the National Longitudinal Survey of Youth Children data, allows measurement of behavior problems (BP) within a developmental perspective linking them to menarcheal timing (MT). In a preliminary analysis, we evaluate the bivariate relationships between BP measured at different devel...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-014-9676-4
更新日期：2015-01-01 00:00:00
abstract：:Mating behavior, including courtship and copulation, is a main component of male fitness, especially in species with no parental care. Variation in this behavior can thus be a target for mate choice and sexual selection, and can lead to evolution. The fruit fly, Drosophila melanogaster, has well-documented complex mal...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-008-9204-5
更新日期：2008-07-01 00:00:00
abstract：:The paradise fish, a small insectivore, coinhabits marshes of Southeast Asia with several predator fish species. Its ability to recognize and avoid harmful fish may depend upon both genetic factors and experience. Here we demonstrate genetic variability between the 20-day-old larvae of two inbred strains of paradise f...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1025601828464
更新日期：1997-05-01 00:00:00
abstract：:This study documented the etiology contributions between anxiety symptoms (AS) and depressive symptoms (DS) from ages 6-12 years. Teachers assessed AS and DS in 1112 twins at 5 time points. A genetic cross-lagged model was used to estimate genetic/environmental contributions to cross-sectional, cross-age and cross-lag...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-019-09988-1
更新日期：2020-03-01 00:00:00
abstract：:Behaviors with high energetic costs may decrease in frequency in domestic animals as a response to selection for increased production. The aim of this study was to quantify production traits, foraging behavior, and social motivation in F2 progeny from a White Leghorn x red junglefowl intercross (n = 751-1046) and to p...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1020880211144
更新日期：2002-11-01 00:00:00
abstract：:The equal environments hypothesis of twin methodology was examined for the variable of similarity of appearance as it affects the personality ratings of young twins. There were two separate samples, the first with 95 pairs of same-sex twins and the second with 111 pairs. The average age of the twins in both samples wa...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01065677
更新日期：1976-01-01 00:00:00
abstract：:Parameters of quantitative genetic models have traditionally been estimated by either algebraic manipulation of familial correlations (or familial mean squares), biometric model fitting, or multiple-group covariance structure analysis. With few exceptions, researchers who have used these methods for the analysis of tw...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01066662
更新日期：1992-05-01 00:00:00
abstract：:The heritability of human personality is well-established. Recent research indicates that nonadditive genetic effects, such as dominance and epistasis, play a large role in personality variation. One possible explanation for the latter finding is that there has been recent selection on human personality. To test this ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-012-9537-y
更新日期：2012-07-01 00:00:00
abstract：:This paper uses data from the National Longitudinal Study of Adolescent Health to examine the extent to which school-level social and institutional factors moderate genetic tendencies to smoke cigarettes. Our analysis relies on a sub-sample of 1,198 sibling and twin pairs nested within 84 schools. We develop a multile...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-008-9197-0
更新日期：2008-05-01 00:00:00
abstract：:Differences between population-typical norms of individual variability were studied in five genetic lines of Japanese quail (Coturnix coturnix japonica); two (BL and RL) were bidirectionally selected for early approach preference between blue and red stimuli, two (Hi and Lo) for high and low imprintabilities to the sa...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01074309
更新日期：1992-09-01 00:00:00
abstract：:Common SNPs in nicotinic acetylcholine receptor genes (CHRN genes) have been associated with drug behaviors and personality traits, but the influence of rare genetic variants is not well characterized. The goal of this project was to identify novel rare variants in CHRN genes in the Center for Antisocial Drug Dependen...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-016-9792-4
更新日期：2016-09-01 00:00:00
abstract：:The transmission of social attitudes has been investigated as a possible model of cultural inheritance in a sample of 3810 twin pairs from the Australian National Health and Medical Research Twin Registry. Six social attitude factors were identified and univariate genetic models fitted to scores on each factor. A join...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01066792
更新日期：1992-01-01 00:00:00
