Abstract:
:This paper uses data from the National Longitudinal Study of Adolescent Health to examine the extent to which school-level social and institutional factors moderate genetic tendencies to smoke cigarettes. Our analysis relies on a sub-sample of 1,198 sibling and twin pairs nested within 84 schools. We develop a multilevel modeling extension of regression-based quantitative genetic techniques to calculate school-specific heritability estimates. We show that smoking onset (h2 = .51) and daily smoking (h2 = .58) are both genetically influenced. Whereas the genetic influence on smoking onset is consistent across schools, we show that schools moderate the heritability of daily smoking. The heritability of daily smoking is the highest within schools in which the most popular students are also smokers and reduced within schools in which the majority of the students are non-Hispanic and white. These findings make important contributions to the literature on gene-environment interactions.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Boardman JD,Saint Onge JM,Haberstick BC,Timberlake DS,Hewitt JKdoi
10.1007/s10519-008-9197-0subject
Has Abstractpub_date
2008-05-01 00:00:00pages
234-46issue
3eissn
0001-8244issn
1573-3297journal_volume
38pub_type
杂志文章abstract::Five species of whale with matrilineal social systems (daughters remain with mothers) have remarkably low levels of mitochondrial DNA diversity. Non-heritable matriline-level demography could reduce genetic diversity but the required conditions are not consistent with the natural histories of the matrilineal whales. T...
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abstract::Reading ability and specific reading disability (SRD) are complex traits involving several cognitive processes and are shaped by a complex interplay of genetic and environmental forces. Linkage studies of these traits have identified several susceptibility loci. Association studies have gone further in detecting candi...
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abstract::Complex illnesses, like depression, are thought to arise from the interplay between psychosocial stressors and genetic predispositions. Approaches that take into account both personal and neighborhood factors and that consider gene regions as well as individual SNPs may be necessary to capture these interactions acros...
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abstract::In this study we examined cross-sectional age differences in means, phenotypic covariance structure, and the underlying genetic and environmental structure of four personality constructs from Cloninger's personality system: Novelty Seeking (NS), Harm Avoidance (HA), Reward Dependence (RD), and Persistence (PS). Study ...
journal_title:Behavior genetics
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更新日期:2003-03-01 00:00:00
abstract::A powerful longitudinal data source, the National Longitudinal Survey of Youth Children data, allows measurement of behavior problems (BP) within a developmental perspective linking them to menarcheal timing (MT). In a preliminary analysis, we evaluate the bivariate relationships between BP measured at different devel...
journal_title:Behavior genetics
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doi:10.1007/s10519-014-9676-4
更新日期:2015-01-01 00:00:00
abstract::This is the first report of data analyses from a consortium of longitudinal genetic-risk studies on offspring of schizophrenic parents (CLOSSER) who were followed from birth or mid-childhood to their early 20's or considerably older ages. Three of the CLOSSER studies provide data to enable us to address long-persistin...
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abstract::If appropriately determined, recombinant-inbred (RI) strain means provide an excellent method for determining genetic correlations among complex characters. However, little systematic attention has been paid to important environmental influences on strain means such as random effects due to litter membership or system...
journal_title:Behavior genetics
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abstract::The effect of the maternal environment on intermale aggression was studied by means of embryo transfer of genetically selected aggressive (SAL) and nonaggressive wild house mice (LAL), and their reciprocal F1's, to standard (NMR1) females. No effect was found on the attack latency scores (ALS), i.e., aggression: all g...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02359756
更新日期:1996-09-01 00:00:00
abstract::The amygdala integrates and coordinates emotional and autonomic responses. The genetics that underlie variation in amygdala structure may be coupled to variation in levels of aggression, fear, anxiety, and affiliated behaviors. We systematically quantified the volume and cell populations of the basolateral amygdala co...
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journal_title:Behavior genetics
pub_type: 杂志文章
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abstract::Taste perception allows most animals to find edible food, potential mates, and avoid ingesting toxic molecules. Intriguingly, a small group of Drosophila taste neurones (expressing Gr66a-Gal4) involved in the perception of bitter substances is also used to detect 7-tricosene (7-T), a male cuticular pheromone. Male fli...
journal_title:Behavior genetics
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doi:10.1007/s10519-009-9286-8
更新日期:2009-09-01 00:00:00
abstract::The paradise fish, a small insectivore, coinhabits marshes of Southeast Asia with several predator fish species. Its ability to recognize and avoid harmful fish may depend upon both genetic factors and experience. Here we demonstrate genetic variability between the 20-day-old larvae of two inbred strains of paradise f...
journal_title:Behavior genetics
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doi:10.1023/a:1025601828464
更新日期:1997-05-01 00:00:00
abstract::Chronic pelvic pain (CPP) is a common condition in women that is difficult to diagnose. Although heritability estimates have been published for some conditions potentially underlying pelvic pain, the heritability of CPP itself has never been investigated. Using data from 623 MZ and 377 DZ female twin pairs aged 29-50 ...
journal_title:Behavior genetics
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doi:10.1007/s10519-004-1017-6
更新日期:2005-03-01 00:00:00
abstract::Interpretation of studies using single gene mutants is complicated by possible epistatic interactions with genetic background. Dopamine D2 receptor (Drd2) knockout mice on a C57BL/6 (B6) background show decreased basal locomotion, ethanol preference and ethanol-induced ataxia. Epistatic interactions were studied by ex...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1023450625826
更新日期:2003-05-01 00:00:00
abstract::In an investigation into the effects of developmental isolation from all conspecifics, the Drosophila willistoni group of six sibling species responded to differing degrees: all six are reproductively isolated from D. paulistorum, the tester species. Drosophila pavlovskiana, a narrow endemic, proved the most vulnerabl...
journal_title:Behavior genetics
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doi:10.1023/a:1021494023660
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abstract::Previous studies have shown associations between single nucleotide polymorphisms (SNPs) in gamma aminobutyric acid receptor alpha 2 (GABRA2) and adolescent conduct disorder (CD) and alcohol dependence in adulthood, but not adolescent alcohol dependence. The present study was intended as a replication and extension of ...
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doi:10.1007/s10519-014-9653-y
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1025633307992
更新日期:1997-03-01 00:00:00
abstract::A complimentary two-phase strategy was used to detect and map quantitative trait loci (QTLs) associated with the basal locomotor response to a saline challenge (10 ml/kg). In phase 1, putative QTLs, significant at p < 0.01 or better, were identified by analysis of the strain means for 25 strains of the B x D recombina...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1001963906258
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pub_type: 杂志文章
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-006-9135-y
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abstract::We review the literature on the familial resemblance of body mass index (BMI) and other adiposity measures and find strikingly convergent results for a variety of relationships. Results from twin studies suggest that genetic factors explain 50 to 90% of the variance in BMI. Family studies generally report estimates of...
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journal_title:Behavior genetics
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02327575
更新日期:1995-11-01 00:00:00
abstract::A new assay was designed, named checker, that measures the individual response to light in the fruitfly Drosophila melanogaster larva. In this assay the Drosophila larva apparently modulates its pattern of locomotion when faced with a choice between a dark and lit environment by orienting its movement towards the dark...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1002090627601
更新日期:2000-01-01 00:00:00
abstract::Callous-unemotional (CU) traits comprise the core symptoms of psychopathy, yet no study has estimated the heritability of CU traits in a community sample of children using an instrument designed solely to assess CU traits. The current study uses data from 339 twin pairs aged 9-14 to examine the reliability and heritab...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-016-9831-1
更新日期:2017-03-01 00:00:00
abstract::The ability to learn and remember is variable within a population of a given species, including humans. This is due in part to genetic variation between individuals. However, only few genes have been identified that contribute to variation in learning and memory. Two inbred mouse strains, C57Bl/6J (B6) and DBA/2J (D2)...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-010-9387-4
更新日期:2011-03-01 00:00:00
abstract::A model of handedness incorporating both genetic and cultural processes is proposed, based on an evolutionary analysis, and maximum-likelihood estimates of its parameters are generated. This model has the characteristics that (i) no genetic variation underlies variation in handedness, and (ii) variation in handedness ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02253372
更新日期:1995-09-01 00:00:00
abstract::As a test of whether sex differences in cognitive functioning are determined by chromosomal constitution or hormonal events, eight subjects whose phenotypic sex differed from their genotypic sex were given a standard intelligence test. The results indicated that differences between verbal and nonverbal abilities corre...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01068210
更新日期:1979-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1021631122461
更新日期:1999-11-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9664-8
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