Abstract:
:Differences between population-typical norms of individual variability were studied in five genetic lines of Japanese quail (Coturnix coturnix japonica); two (BL and RL) were bidirectionally selected for early approach preference between blue and red stimuli, two (Hi and Lo) for high and low imprintabilities to the same stimuli, and the fifth (CL) was an unselected genetic control line. Selection resulted in reliably divergent extreme choice performances and imprintabilities and in progressively increasing choice variances in the BL x RL hybrids and the Hi imprintability line. Experimentation tested and rejected the hypotheses that correlated selection of synergistically acting but otherwise extraneous stimulus influences, social interaction effects, or phototactic and short-term learning effects may have been responsible for the observed large variance increases. An alternative interpretation is discussed, according to which directional selection relaxes the genetic buffering and the variance increases reflect the resulting developmental instability of the trait.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Kovach JKdoi
10.1007/BF01074309subject
Has Abstractpub_date
1992-09-01 00:00:00pages
575-84issue
5eissn
0001-8244issn
1573-3297journal_volume
22pub_type
杂志文章abstract::Previous studies suggest that brain opioid activity decreases aggression in animal models. The main objective of the current study was to examine the possible genetic relationship between intermale aggression and brain levels of enkephalins, endorphins, and dynorphins in 11 inbred strains of mice. Pursuit, rattling, a...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1025774716976
更新日期:2003-09-01 00:00:00
abstract::It is well established that many continuously distributed traits have a heritable component. However, it is often difficult to communicate to the general public the meaning of quantitative estimates of heritability. To address this problem, the present paper introduces a heuristic for communicating heritability to non...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1025670316169
更新日期:1997-09-01 00:00:00
abstract::In a study designed to investigate genotype-environment interaction, eight strains of laboratory rats were crossbred in a replicated diallel cross employing infantile stimulation and its absence as environmental treatments. This paper reports on measures of the acquisition of two-way escape-avoidance conditioning, com...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01070816
更新日期:1981-07-01 00:00:00
abstract::Parameters of quantitative genetic models have traditionally been estimated by either algebraic manipulation of familial correlations (or familial mean squares), biometric model fitting, or multiple-group covariance structure analysis. With few exceptions, researchers who have used these methods for the analysis of tw...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066662
更新日期:1992-05-01 00:00:00
abstract::Recent studies have identified genes that influence the length of the circadian period maintained by mice housed under constant lighting conditions. However, a less studied circadian activity variable is the amplitude of daily oscillations in locomotor activity. This parameter reflects spontaneous activity exhibited u...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1021657800287
更新日期:1999-09-01 00:00:00
abstract::The facts concerning Kammerer's case are reviewed. Koestler's view that Krammerer was unjustly accused is presented and shown to be incorrect. ...
journal_title:Behavior genetics
pub_type: 传,历史文章,杂志文章
doi:10.1007/BF01066805
更新日期:1975-04-01 00:00:00
abstract::Almost 40 years ago, evidence from large studies of adult twins and their relatives suggested that between 30 and 60% of the variance in social and political attitudes could be explained by genetic influences. However, these findings have not been widely accepted or incorporated into the dominant paradigms that explai...
journal_title:Behavior genetics
pub_type: 杂志文章,meta分析
doi:10.1007/s10519-014-9648-8
更新日期:2014-05-01 00:00:00
abstract::Knowledge about the proportion of markers without effects (p( 0 )) and the effect sizes in large scale genetic studies is important to understand the basic properties of the data and for applications such as the control of false discoveries and designing adequately powered replication studies. Many p(0) estimators hav...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-009-9321-9
更新日期:2010-05-01 00:00:00
abstract::The attempt to characterize high- and low-selected lines on new variables poses serious interpretative problems when replicate lines are not available. Modest but significant line differences on new measures may be due to genetic drift totally irrelevant to the originally selected trait. Often these differences are ex...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066250
更新日期:1989-07-01 00:00:00
abstract::In a sample of 1,940 Dutch 7-year-old twin pairs we studied the etiology of individual differences in Internalizing and Externalizing behavioral problems. For the majority of twins in the sample, both maternal and paternal ratings of behavioral problems were obtained from the Child Behavior Checklist. This made it pos...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1025369525924
更新日期:2003-07-01 00:00:00
abstract::Parameter estimates from analyses of univariate twin data usually do not reflect the uncertainty due to the model selection phase of the data analysis. To address the effect of model selection uncertainty on parameter estimates, we introduce frequentist model-averaged estimators for univariate twin data analysis that ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-006-9065-8
更新日期:2006-09-01 00:00:00
abstract::In the present study we evaluated long term memory in twenty individuals with molecularly confirmed diagnosis of Noonan syndrome and LEOPARD syndrome, two disorders caused by mutations in genes coding transducers participating in the RAS-MAPK signaling cascade. The profile of explicit long term memory abilities was in...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-011-9446-5
更新日期:2011-05-01 00:00:00
abstract::This paper uses data from the National Longitudinal Study of Adolescent Health to examine the extent to which school-level social and institutional factors moderate genetic tendencies to smoke cigarettes. Our analysis relies on a sub-sample of 1,198 sibling and twin pairs nested within 84 schools. We develop a multile...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-008-9197-0
更新日期:2008-05-01 00:00:00
abstract::Workers from colonies of Cape honeybees show marked phenotypic differences in performance in proboscis extension reflex (PER) conditioning. Analysis of these differences using parthenogenetic offspring groups permitted the estimation of genotypic values and revealed a high degree of genetic variability that is evident...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065820
更新日期:1991-05-01 00:00:00
abstract::In previous electrophysiological experiments from hypopigmented animals (mice, rats, rabbits), single-unit recordings from both retinal ganglion axons and cells in the superior colliculus have demonstrated an increase in threshold in the dark-adapted state which is roughly proportional to the ocular melanin concentrat...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067442
更新日期:1993-07-01 00:00:00
abstract::Components of the communication system between infant and adult rodents based on ultrasonic vocalizations (USVs) of infants are analyzed. USVs are most often emitted from a pup lost outside the nest in response to changes of: (i) body temperature, (ii) contact with adults/littermates, (iii) handling, and (iv) smell. T...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1007/s10519-004-0853-8
更新日期:2005-01-01 00:00:00
abstract::A central issue in psychiatric genetics is whether positive findings replicate. Zubenko et al. (2002b, Mol. Psychiatry 7:460-467) reported an association of the 124-bp allele of D2S2944 with recurrent early-onset major depression for females. We tested for association of this allele to continuous measures of anxiety, ...
journal_title:Behavior genetics
pub_type: 杂志文章,多中心研究
doi:10.1007/s10519-005-9006-y
更新日期:2006-01-01 00:00:00
abstract::Latent variable models are used in biological and social sciences to investigate characteristics that are not directly measurable. The generation of individual scores of latent variables can simplify subsequent analyses. However, missing measurements in real data complicate the calculation of scores. Missing observati...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-006-9123-2
更新日期:2007-03-01 00:00:00
abstract::Manipulation of endogenous levels of the GABAergic neurosteroid allopregnanolone alters sensitivity to some effects of ethanol. Chronic ethanol withdrawal decreases activity and expression of 5α-reductase-1, an important enzyme in allopregnanolone biosynthesis encoded by the 5α-reductase-1 gene (Srd5a1). The present s...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9691-5
更新日期:2015-05-01 00:00:00
abstract::The most common alternative to a genetic explanation of left-handedness is that sinistrality arises because of birth stress factors. In a sample of 1398 subjects, the association between birth stress and left-handedness was confirmed. More importantly, it was found that left-handed mothers are more likely to have birt...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02327575
更新日期:1995-11-01 00:00:00
abstract::A powerful longitudinal data source, the National Longitudinal Survey of Youth Children data, allows measurement of behavior problems (BP) within a developmental perspective linking them to menarcheal timing (MT). In a preliminary analysis, we evaluate the bivariate relationships between BP measured at different devel...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9676-4
更新日期:2015-01-01 00:00:00
abstract::During middle childhood, continuous changes occur in electroencephalogram (EEG) coherence, an index of cortico-cortical connectivity of the brain. In the gradual development of EEG coher ence, occasional "growth spurts" are observed which coincide with periods of discontinuous development in cognition. Discontinuous d...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1013357714500
更新日期:2001-11-01 00:00:00
abstract::Bullying comes in different forms, yet most previous genetically-sensitive studies have not distinguished between them. Given the serious consequences and the high prevalence of bullying, it is remarkable that the aetiology of bullying and its different forms has been under-researched. We present the first study to in...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-019-09968-5
更新日期:2019-09-01 00:00:00
abstract::Artificial selection was used to establish different levels of agonistic behavior in laboratory-reared wild female Mus musculus. A within-family selection design with replicated high and low lines and two nonselected control lines was employed. Females only were tested at 8 weeks of age on 2 consecutive days. Testing ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065725
更新日期:1976-07-01 00:00:00
abstract::Two ongoing selective breeding projects have produced mice that display divergent analgesic responses to morphine. These two projects have selected for similar phenotypes: high and low levorphanol analgesia (HAR/LAR lines; Portland, OR) and high and low swim stress-induced analgesia (HA/LA lines; Jastrzebiec, Poland)....
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02197290
更新日期:1995-07-01 00:00:00
abstract::Variance components analysis provides an efficient method for performing linkage analysis for quantitative traits. However, power and type 1 error of variance components-based likelihood ratio testing may be affected when phenotypic data are nonnormally distributed (especially with high values of kurtosis) and there i...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/B:BEGE.0000013729.26354.da
更新日期:2004-03-01 00:00:00
abstract::Previously, sequence variation in the glucocorticoid (GR) and mineralocorticoid (MR) receptor genes (NR3C1 and NR3C2, respectively) have been found to be associated with physiological stress responses to social stress tests in small samples of adult men and oral contraceptives (OC) using women. Associations between si...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-010-9385-6
更新日期:2011-03-01 00:00:00
abstract::Genome wide complex trait analysis (GCTA) is extended to include environmental effects of the maternal genotype on offspring phenotype ("maternal effects", M-GCTA). The model includes parameters for the direct effects of the offspring genotype, maternal effects and the covariance between direct and maternal effects. A...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9666-6
更新日期:2014-09-01 00:00:00
abstract::The present study explored the effects of infantile stimulation (i.e., neonatal handling or NH) on the performance of 18-month-old Roman high-avoidance (RHA/Verh) and low-avoidance (RLA/Verh) rats in a swimming pool matching-to-place (SPMP) test. This test (also called repeated acquisition and place learning-set parad...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1015253807488
更新日期:2002-03-01 00:00:00
abstract::Gonadotropin-releasing hormone (GnRH), having a highly conserved structure across mammalian species, plays a pivotal role in the control of the neuroendocrine events and the inherent sexual behaviors essential for reproductive function. Recent advances in molecular genetic technology have contributed greatly to the in...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1007/BF02359383
更新日期:1996-05-01 00:00:00