Abstract:
:The attempt to characterize high- and low-selected lines on new variables poses serious interpretative problems when replicate lines are not available. Modest but significant line differences on new measures may be due to genetic drift totally irrelevant to the originally selected trait. Often these differences are exaggerated by inappropriate analysis using individual subject measurements rather than family means. Mean differences in high- and low-selected lines on new characters should not be ascribed to the originally selected trait unless (1) genetic drift can be estimated through the use of replicate lines, (2) the standardized mean difference exceeds 1/4 of the equivalent difference on the original selected trait, or (3) strong predictions involving multiple noncontingent measures are unconditionally supported. For most purposes of analysis, line means can be considered individual data points which can be used to compute correlations among measures. An alternative to selection with replicates--two-stage testing of commercially available inbred strains--should be considered when large genetic correlations between the characters are expected.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Henderson NDdoi
10.1007/BF01066250subject
Has Abstractpub_date
1989-07-01 00:00:00pages
473-502issue
4eissn
0001-8244issn
1573-3297journal_volume
19pub_type
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journal_title:Behavior genetics
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067533
更新日期:1994-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01070816
更新日期:1981-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067550
更新日期:1993-01-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067442
更新日期:1993-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065462
更新日期:1981-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/BF01076179
更新日期:1994-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10519-016-9823-1
更新日期:2017-03-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1025369525924
更新日期:2003-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1007/s10519-005-3227-y
更新日期:2005-05-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065820
更新日期:1991-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:1996-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-05-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01074309
更新日期:1992-09-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066164
更新日期:1989-05-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-005-2868-1
更新日期:2005-09-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01071563
更新日期:1994-11-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066277
更新日期:1977-05-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章,meta分析
doi:10.1007/s10519-014-9648-8
更新日期:2014-05-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章,多中心研究
doi:10.1007/s10519-005-9006-y
更新日期:2006-01-01 00:00:00