Abstract:
:The present study explored the effects of infantile stimulation (i.e., neonatal handling or NH) on the performance of 18-month-old Roman high-avoidance (RHA/Verh) and low-avoidance (RLA/Verh) rats in a swimming pool matching-to-place (SPMP) test. This test (also called repeated acquisition and place learning-set paradigm) consists of administering pairs of consecutive trials in the Morris water maze. The difference between each "odd" and the consecutive "even" trial of a trial pair is considered to be a measure of working memory. The same rats were first tested for exploration and novelty-seeking in a hole-board test in the presence of novel objects, which showed that RHA/Verh rats were more explorative than their RLA/Verh counterparts, and that NH treatment augmented exploration in RLA/Verh rats, generally eliminating the genetically-based differences between the lines. RHA/Verh rats performed less efficiently than RLA/Verh rats in the SPMP test, and NH facilitated acquisition in the early stages of training in both rat lines, an effect that was presumably due to an improvement in the acquisition of spatial reference information. Performance during training also indicated that RHA/Verh rats showed less differentiated behavior between odd and even trials, indicating a relative working memory deficit at advanced ages in that rat line.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Aguilar R,Escorihuela RM,Gil L,Tobeña A,Fernández-Teruel Adoi
10.1023/a:1015253807488subject
Has Abstractpub_date
2002-03-01 00:00:00pages
127-34issue
2eissn
0001-8244issn
1573-3297journal_volume
32pub_type
杂志文章abstract::We used an alternate age variable, functional biological age (fBioAge), which was based on performance on functional body measures. The aim was to examine development of fBioAge across the adult life span, and to also examine potential gender differences and genetic and environmental influences on change with age. We ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-017-9851-5
更新日期:2017-07-01 00:00:00
abstract::A powerful longitudinal data source, the National Longitudinal Survey of Youth Children data, allows measurement of behavior problems (BP) within a developmental perspective linking them to menarcheal timing (MT). In a preliminary analysis, we evaluate the bivariate relationships between BP measured at different devel...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9676-4
更新日期:2015-01-01 00:00:00
abstract::Sixty-six mice of 11 genetic stocks (the Bailey recombinant inbred strains CXBD, CXBE, CXBG, CXBH, CXBI, CXBJ, CXBK; their progenitor strains, BALB/cBy and C57BL/6By: and the reciprocal hybrids, B6CF and CB6F) were tested in a two-compartment apparatus and in a shuttlebox, with five measures taken relating to activity...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066277
更新日期:1977-05-01 00:00:00
abstract::Twin studies are useful for assessing the relative importance of genetic or heritable component from the environmental component. In this paper we develop a methodology to study the heritability of age-at-onset or lifespan traits, with application to analysis of twin survival data. Due to limited period of observation...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-007-9150-7
更新日期:2007-07-01 00:00:00
abstract::Structural equation modeling (SEM) provides a flexible tool to carry out genetic analyses of family and twin data. The basic model which decomposes the variance between and within families for a particular trait into genetic and non-genetic components can be generalized to multivariate and/or longitudinal data, incorp...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-005-2791-5
更新日期:2005-07-01 00:00:00
abstract::Inhibitory control (IC) is a dimension of child temperament that emerges in toddlerhood and involves the ability to regulate behavior in response to instructions or expectations. In general, children with low levels of IC have more cognitive and social difficulties, and higher levels of problem behaviors. Unfortunatel...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-009-9316-6
更新日期:2010-05-01 00:00:00
abstract::If appropriately determined, recombinant-inbred (RI) strain means provide an excellent method for determining genetic correlations among complex characters. However, little systematic attention has been paid to important environmental influences on strain means such as random effects due to litter membership or system...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1007/BF01066634
更新日期:1992-11-01 00:00:00
abstract::Genetic heritability (h2) of alcohol use is reported to be greater in rural dwellers, distressed marriages, low socioeconomic status, in girls who are unmarried or lacking closeness with their parents or religious upbringing, in less-educated men, and in adolescents with peers using alcohol. However, these are all ris...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-020-10005-z
更新日期:2020-09-01 00:00:00
abstract::Genetic and environmental determinants of self-reported alcohol consumption were investigated in a sample of 2513 twin pairs who were first assessed at age 16 and were followed-up at age 17. At age 16, 77% of the sample was drinking, and 65% of drinkers reported drinking to intoxication. Both drinking and drinking to ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1021631122461
更新日期:1999-11-01 00:00:00
abstract::Behaviors with high energetic costs may decrease in frequency in domestic animals as a response to selection for increased production. The aim of this study was to quantify production traits, foraging behavior, and social motivation in F2 progeny from a White Leghorn x red junglefowl intercross (n = 751-1046) and to p...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1020880211144
更新日期:2002-11-01 00:00:00
abstract::Mating behavior, including courtship and copulation, is a main component of male fitness, especially in species with no parental care. Variation in this behavior can thus be a target for mate choice and sexual selection, and can lead to evolution. The fruit fly, Drosophila melanogaster, has well-documented complex mal...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-008-9204-5
更新日期:2008-07-01 00:00:00
abstract::Components of the communication system between infant and adult rodents based on ultrasonic vocalizations (USVs) of infants are analyzed. USVs are most often emitted from a pup lost outside the nest in response to changes of: (i) body temperature, (ii) contact with adults/littermates, (iii) handling, and (iv) smell. T...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1007/s10519-004-0853-8
更新日期:2005-01-01 00:00:00
abstract::The role of the period of the environmental cycle during gestation and infancy on the circadian period of adult hamsters was studied. Tau-mutant hamsters of all three genotypes (+/+, 24-h circadian period; +/tau, 22-h period; tau/tau, 20-h period) were conceived and raised under either a 20-h light-dark cycle or a 24-...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1021428209122
更新日期:1998-03-01 00:00:00
abstract::Manipulation of endogenous levels of the GABAergic neurosteroid allopregnanolone alters sensitivity to some effects of ethanol. Chronic ethanol withdrawal decreases activity and expression of 5α-reductase-1, an important enzyme in allopregnanolone biosynthesis encoded by the 5α-reductase-1 gene (Srd5a1). The present s...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9691-5
更新日期:2015-05-01 00:00:00
abstract::In this article, we successfully apply the novel model selection method, Bayesian composite model space approach which has been used to map quantitative trait loci (QTL) for allelic substitution model, to map QTL for variance component model. The novel model selection approach has two advantages compared to the revers...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-009-9259-y
更新日期:2009-05-01 00:00:00
abstract::Based on the reviewed literature and the data presented in this paper, conclusions can be drawn with respect to the validity of the WAG/Rij strain of rats as a model for absence epilepsy in humans. The view that the WAG/Rij model has "face validity" is supported by the simultaneous presence of clinical and electroence...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1023/a:1026179013847
更新日期:2003-11-01 00:00:00
abstract::The transmission of social attitudes has been investigated as a possible model of cultural inheritance in a sample of 3810 twin pairs from the Australian National Health and Medical Research Twin Registry. Six social attitude factors were identified and univariate genetic models fitted to scores on each factor. A join...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066792
更新日期:1992-01-01 00:00:00
abstract::We report on a cross-syndrome comparison of hand, foot, eye and ear laterality in three groups of individuals with different genetic disorders (trisomy 21, del7q11.23, and del22q11.2) to test the relationship between atypical laterality and intellectual disability. These groups were compared to a group of typically de...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-011-9465-2
更新日期:2011-05-01 00:00:00
abstract::Taste perception allows most animals to find edible food, potential mates, and avoid ingesting toxic molecules. Intriguingly, a small group of Drosophila taste neurones (expressing Gr66a-Gal4) involved in the perception of bitter substances is also used to detect 7-tricosene (7-T), a male cuticular pheromone. Male fli...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-009-9286-8
更新日期:2009-09-01 00:00:00
abstract::Courtship song serves as a sexual signal and may contribute to reproductive isolation between closely related species. Using lines of Drosophila pseudoobscura experimentally selected under different sexual selection regimes, we tested whether increased promiscuity and enforced monogamy led to evolutionary changes in c...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-005-3217-0
更新日期:2005-05-01 00:00:00
abstract::This study documented the etiology contributions between anxiety symptoms (AS) and depressive symptoms (DS) from ages 6-12 years. Teachers assessed AS and DS in 1112 twins at 5 time points. A genetic cross-lagged model was used to estimate genetic/environmental contributions to cross-sectional, cross-age and cross-lag...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-019-09988-1
更新日期:2020-03-01 00:00:00
abstract::Martin and Wilson (1982) describe two forms of sampling bias in twin studies. One is "hard selection," where individuals above a threshold participate, and those below do not. The second is "soft selection," where the probability of including a pair of relatives varies over the range of the character. We present an al...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065901
更新日期:1989-03-01 00:00:00
abstract::We analyzed the genetic architecture of prepubertal development of relative weight to height in 216 monozygotic and 159 dizygotic complete Japanese twin pairs (52% girls). Ponderal index at birth (kg/m(3)) and body mass index (BMI, kg/m(2)) from 1 to 11 years of age were used. Additive genetic factors explained the ma...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-010-9380-y
更新日期:2011-03-01 00:00:00
abstract::Alterations of peripheral magnesium (Mg) concentration have been reported in association with several behavioral disorders and sleep organization. Blood Mg regulation is under a strong genetic control, whereas brain Mg regulation does not seem to be affected. We have studied peripheral and central levels of Mg and ana...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1012790321071
更新日期:2001-09-01 00:00:00
abstract::A complimentary two-phase strategy was used to detect and map quantitative trait loci (QTLs) associated with the basal locomotor response to a saline challenge (10 ml/kg). In phase 1, putative QTLs, significant at p < 0.01 or better, were identified by analysis of the strain means for 25 strains of the B x D recombina...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1001963906258
更新日期:2000-05-01 00:00:00
abstract::Variance components analysis provides an efficient method for performing linkage analysis for quantitative traits. However, power and type 1 error of variance components-based likelihood ratio testing may be affected when phenotypic data are nonnormally distributed (especially with high values of kurtosis) and there i...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/B:BEGE.0000013729.26354.da
更新日期:2004-03-01 00:00:00
abstract::Results obtained from previous studies of word recognition, reading component skills, and reading composite measures suggest that genetic factors may be more important as a cause for reading disability among children with higher IQ scores than among those with lower IQ scores. To investigate the genetic etiology of re...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1016069012111
更新日期:2002-05-01 00:00:00
abstract::To extend Purcell's well known ACE model in testing gene by measured environment interactions (GxM) in behavior genetic designs, Rathouz et al. considered a broader class of models for quantifying and testing such interactions. Only a sub-group of these extended models have been investigated for their statistical oper...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-015-9710-1
更新日期:2015-07-01 00:00:00
abstract::Fingerprints and handedness were measured in 2169 subjects. Left-handers were more likely to have an increased number of arches and radial loops, while having fewer whorls and lower pattern intensity than right-handers. Analyzing by hand and digit, the differences were most marked on the left hand, which showed signif...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067817
更新日期:1994-03-01 00:00:00
abstract::In a study designed to investigate genotype-environment interaction, eight strains of laboratory rats were crossbred in a replicated diallel cross employing infantile stimulation and its absence as environmental treatments. This paper reports on measures of the acquisition of two-way escape-avoidance conditioning, com...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01070816
更新日期:1981-07-01 00:00:00