Abstract:
:In a study designed to investigate genotype-environment interaction, eight strains of laboratory rats were crossbred in a replicated diallel cross employing infantile stimulation and its absence as environmental treatments. This paper reports on measures of the acquisition of two-way escape-avoidance conditioning, comprising number of avoidances, avoidance and escape latencies, and intertrial and presessional crossings, which were subjected to biometrical genetical analysis, all but the last successfully. Additive variation was prominent throughout and some measures showed directional dominance. Effects of stimulation were seen in avoidance number and crossings. The analysis of avoidances by successive blocks of trials using covariance:variance graphs revealed differences in the way the strains varied with respect to the changing relationships of proportions of dominant and recessive alleles governing this behavior. The results are discussed in the light of previous data and of their evolutionary implications.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Wilcock J,Fulker DW,Broadhurst PLdoi
10.1007/BF01070816subject
Has Abstractpub_date
1981-07-01 00:00:00pages
339-58issue
4eissn
0001-8244issn
1573-3297journal_volume
11pub_type
杂志文章abstract::The region containing ROBO1 (Chromosome 3p12.3) has been implicated as a susceptibility gene for reading disorder and language deficit by translocation and linkage data. No association studies have yet been reported supporting any candidate gene. Here we report the first association of this gene with language deficits...
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