Abstract：
:Genetic and environmental determinants of self-reported alcohol consumption were investigated in a sample of 2513 twin pairs who were first assessed at age 16 and were followed-up at age 17. At age 16, 77% of the sample was drinking, and 65% of drinkers reported drinking to intoxication. Both drinking and drinking to intoxication increased at the 1-year follow-up. Model fitting indicated that most of the variance in drinking initiation was due to shared environmental effects but that shared environmental effects were less important, and additive genetic effects were more important, in explaining frequency of drinking among subjects who had already initiated drinking. Similarly, shared environmental effects explained most of the variation in initiation of drinking to intoxication but were less important in explaining frequency of intoxication among subjects who had already initiated drinking to intoxication. The magnitude of genetic and environmental estimates for males and females did not differ significantly, but it was clear that either different genetic factors or different shared environmental factors were influencing males and females. For all drinking variables studied, shared environmental effects decreased from age 16 to age 17, while additive genetic effects increased from age 16 to age 17.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Viken RJ,Kaprio J,Koskenvuo M,Rose RJdoi
10.1023/a:1021631122461subject
Has Abstractpub_date
1999-11-01 00:00:00pages
455-61issue
6eissn
0001-8244issn
1573-3297journal_volume
29pub_type
杂志文章abstract：:This note reports data on parent-child and spouse resemblance on the Wechsler intelligence scales, the WISC and WAIS. Test data on parents and one male 10-year-old child from 55 Canadian families are used to estimate father-son, mother-son, midparent-son, and father-mother correlations on 11 comparable subscales and o...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01073209
更新日期：1975-10-01 00:00:00
abstract：:A complimentary two-phase strategy was used to detect and map quantitative trait loci (QTLs) associated with the basal locomotor response to a saline challenge (10 ml/kg). In phase 1, putative QTLs, significant at p < 0.01 or better, were identified by analysis of the strain means for 25 strains of the B x D recombina...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1001963906258
更新日期：2000-05-01 00:00:00
abstract：:Genetic strains of mice represent an important resource for research on the biological determinants of complex diseases and behavioral phenotypes. To date, the approaches used have had little success in identifying causal genes. We have evaluated brain gene expression in C57BL/6J (B6) and DBA/2J (D2) inbred mouse stra...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/B:BEGE.0000023648.78190.ee
更新日期：2004-07-01 00:00:00
abstract：:Based on the reviewed literature and the data presented in this paper, conclusions can be drawn with respect to the validity of the WAG/Rij strain of rats as a model for absence epilepsy in humans. The view that the WAG/Rij model has "face validity" is supported by the simultaneous presence of clinical and electroence...
journal_title：Behavior genetics
pub_type： 杂志文章,评审
doi：10.1023/a:1026179013847
更新日期：2003-11-01 00:00:00
abstract：:To study the relationship between genetics and epilepsy, Wistar rats susceptible to audiogenic seizure were selected from the main breeding stock of the Ribeirão Preto School of Medicine at the University of São Paulo, Brazil, and inbred. The criteria for selection were the highest seizure severity index (SI) and shor...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1021099432759
更新日期：2003-01-01 00:00:00
abstract：:Gonadotropin-releasing hormone (GnRH), having a highly conserved structure across mammalian species, plays a pivotal role in the control of the neuroendocrine events and the inherent sexual behaviors essential for reproductive function. Recent advances in molecular genetic technology have contributed greatly to the in...
journal_title：Behavior genetics
pub_type： 杂志文章,评审
doi：10.1007/BF02359383
更新日期：1996-05-01 00:00:00
abstract：:We present a repeated-measures, genetic analysis of ethanol-induced anesthesia (sleep time) in mice from the inbred long-sleep (ILS) and short-sleep (ISS) strains of mice and their derived F1 and F2 generations. Mice (total N > 1300) were administered a 4.1 g/kg intraperitoneal dose of ethanol at two times, 7 to 10 da...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF02197243
更新日期：1995-01-01 00:00:00
abstract：:The conditioned and reflex parameters in rat lines selected for the threshold of excitability (a fundamental characteristics of the functional state of the nervous system) were estimated. This measure is based on the response of the tibial nerve to electrical stimulation, which gives a general indication of the level ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01067986
更新日期：1993-09-01 00:00:00
abstract：:Knowledge about the proportion of markers without effects (p( 0 )) and the effect sizes in large scale genetic studies is important to understand the basic properties of the data and for applications such as the control of false discoveries and designing adequately powered replication studies. Many p(0) estimators hav...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-009-9321-9
更新日期：2010-05-01 00:00:00
abstract：:Roman high- and low-avoidance (RHA/Verh and RLA/Verh) rats are selected and bred for extreme divergence in two-way active avoidance acquisition. In addition, compared to RLA/Verh rats, RHA/Verh rats are (behaviorally and physiologically) less anxious or reactive to stressors, show increased novelty (sensation)-seeking...
journal_title：Behavior genetics
pub_type： 杂志文章,评审
doi：10.1023/a:1021400830503
更新日期：1997-11-01 00:00:00
abstract：:Data from two twin studies were used to address two related questions. First, is there any association between handedness and specific speech and language impairment (SSLI) in children? Second, is there genetic influence on individual differences in handedness and, if so, are the same genes implicated in the cause of ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1012239617367
更新日期：2001-07-01 00:00:00
abstract：:Social aggregations of free-ranging cattle were studied in the Sonoran Desert of Mexico. Cows reared with animals of their own breed in isolation from other breeds maintained segregated social groups. Cows raised together in a mixed herd containing other breeds allied themselves with herd-mates regardless of breed. Ca...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01065562
更新日期：1990-05-01 00:00:00
abstract：:This study used a theoretically-derived set of items of the Achenbach System of Empirically Based Assessment to develop the Achenbach Self-Control Scale (ASCS) for 7-16 year olds. Using a large dataset of over 20,000 children, who are enrolled in the Netherlands Twin Register, we demonstrated the psychometric properti...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-018-9887-1
更新日期：2018-03-01 00:00:00
abstract：:Genetic and environmental influences in the determination of individual differences in self-reported symptoms of separation anxiety (SAD), overanxious disorder (OAD), and manifest anxiety (MANX) were evaluated in children and adolescents for three age groups (8-10, 11-13, and 14-16). Symptom counts for SAD and OAD wer...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1025607107566
更新日期：1997-01-01 00:00:00
abstract：:The behaviors of male mice of the C57BL/6J (C57), CBA/Lac (CBA) and BALB/c (BALB) strains have been studied in the plus-maze and open field tests for estimation of state anxiety in the stressful novel conditions, and in the cubic box test (exploration of novel cubic box) and the partition test (behavioral reactivity t...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1001999020138
更新日期：2000-03-01 00:00:00
abstract：:Chronic pelvic pain (CPP) is a common condition in women that is difficult to diagnose. Although heritability estimates have been published for some conditions potentially underlying pelvic pain, the heritability of CPP itself has never been investigated. Using data from 623 MZ and 377 DZ female twin pairs aged 29-50 ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-004-1017-6
更新日期：2005-03-01 00:00:00
abstract：:In this study we examined cross-sectional age differences in means, phenotypic covariance structure, and the underlying genetic and environmental structure of four personality constructs from Cloninger's personality system: Novelty Seeking (NS), Harm Avoidance (HA), Reward Dependence (RD), and Persistence (PS). Study ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1022558002760
更新日期：2003-03-01 00:00:00
abstract：:Selective breeding for initial sensitivity to ethanol has been carried out by a number of investigators in order to investigate the mechanisms by which ethanol brings about a myriad of effects on the mammalian central nervous system. In addition the availability of these selectively bred animals provides clues to the ...
journal_title：Behavior genetics
pub_type： 杂志文章,评审
doi：10.1007/BF01067420
更新日期：1993-03-01 00:00:00
abstract：:In this article, we successfully apply the novel model selection method, Bayesian composite model space approach which has been used to map quantitative trait loci (QTL) for allelic substitution model, to map QTL for variance component model. The novel model selection approach has two advantages compared to the revers...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-009-9259-y
更新日期：2009-05-01 00:00:00
abstract：:This study documented the etiology contributions between anxiety symptoms (AS) and depressive symptoms (DS) from ages 6-12 years. Teachers assessed AS and DS in 1112 twins at 5 time points. A genetic cross-lagged model was used to estimate genetic/environmental contributions to cross-sectional, cross-age and cross-lag...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-019-09988-1
更新日期：2020-03-01 00:00:00
abstract：:Individuals involved in a social interaction exhibit different behavioral traits that, in combination, form the individual's behavioral responses. Selectively bred strains of silver foxes (Vulpes vulpes) demonstrate markedly different behaviors in their response to humans. To identify the genetic basis of these behavi...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-016-9815-1
更新日期：2017-01-01 00:00:00
abstract：:Genetic heritability (h2) of alcohol use is reported to be greater in rural dwellers, distressed marriages, low socioeconomic status, in girls who are unmarried or lacking closeness with their parents or religious upbringing, in less-educated men, and in adolescents with peers using alcohol. However, these are all ris...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-020-10005-z
更新日期：2020-09-01 00:00:00
abstract：:A genetic analysis of differences in reactivity to early exposure of female BALB/cBy and C57BL/6By mice to testosterone was performed using the C x B recombinant-inbred (RI) strains. RI female mice were given a single injection of 1 mg of testosterone propionate on day 4 of life and observed in adulthood in the presen...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01070741
更新日期：1990-01-01 00:00:00
abstract：:A recent controversy has given reason to examine the place of Burt's data among other behavioral genetic data on IQ. Although Burt's kinship correlations are higher than the average of other studies, his results are generally consistent with other data. ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01067708
更新日期：1978-01-01 00:00:00
abstract：:The escape efficiency of two closely related species of frogs, Odontophrynus cultripes (2n = 22) and the tetraploid O. americanus (4n = 44), were compared in a shuttle box and under simulated naturalistic conditions. O. americanus was generally superior to O. cultripes, and females tended to outperform males within bo...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01065462
更新日期：1981-05-01 00:00:00
abstract：:The attempt to characterize high- and low-selected lines on new variables poses serious interpretative problems when replicate lines are not available. Modest but significant line differences on new measures may be due to genetic drift totally irrelevant to the originally selected trait. Often these differences are ex...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01066250
更新日期：1989-07-01 00:00:00
abstract：:Lurcher mutant mice were impaired in spatial orientation and motor coordination in comparison to normal mice. Both groups improved across days in both invisible and visible water maze platform conditions. Contrary to normal mice, lurcher mutants did not improve over days in terms of the time taken to reach a side-bar ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01071563
更新日期：1994-11-01 00:00:00
abstract：:Workers from colonies of Cape honeybees show marked phenotypic differences in performance in proboscis extension reflex (PER) conditioning. Analysis of these differences using parthenogenetic offspring groups permitted the estimation of genotypic values and revealed a high degree of genetic variability that is evident...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01065820
更新日期：1991-05-01 00:00:00
abstract：:Previous studies suggest that brain opioid activity decreases aggression in animal models. The main objective of the current study was to examine the possible genetic relationship between intermale aggression and brain levels of enkephalins, endorphins, and dynorphins in 11 inbred strains of mice. Pursuit, rattling, a...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1025774716976
更新日期：2003-09-01 00:00:00
abstract：:Genomewide scan, as shown by recently published linkage studies on the behavior of mice or in psychiatry, provides evidence for replicated quantitative trait loci (QTL). Several studies of Alzheimer's disease have demonstrated the promise of moving from clinical diagnoses to biological signs for psychiatric investigat...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1010222328509
更新日期：2001-01-01 00:00:00
