Abstract：
:A study was conducted to identify quantitative trait loci (QTLs) that affect learning in honeybees. Two F1 supersister queens were produced from a cross between two established lines that had been selected for differences in the speed at which they reverse a learned discrimination between odors. Different families of haploid drones from two of these F1 queens were evaluated for two kinds of learning performance--reversal learning and latent inhibition--which previously showed correlated selection responses. Random amplified polymorphic DNA markers were scored from recombinant, haploid drone progeny that showed extreme manifestations of learning performance. Composite interval mapping procedures identified two QTLs for reversal learning (lrn2 and lrn3: LOD, 2.45 and 2.75, respectively) and one major QTL for latent inhibition (lrn1: LOD, 6.15). The QTL for latent inhibition did not map to either of the linkage groups that were associated with reversal learning. Identification of specific genes responsible for these kinds of QTL associations will open up new windows for better understanding of genes involved in learning and memory.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Chandra SB,Hunt GJ,Cobey S,Smith BHdoi
10.1023/a:1012227308783subject
Has Abstractpub_date
2001-05-01 00:00:00pages
275-85issue
3eissn
0001-8244issn
1573-3297journal_volume
31pub_type
杂志文章abstract：:Genetic strains of mice represent an important resource for research on the biological determinants of complex diseases and behavioral phenotypes. To date, the approaches used have had little success in identifying causal genes. We have evaluated brain gene expression in C57BL/6J (B6) and DBA/2J (D2) inbred mouse stra...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/B:BEGE.0000023648.78190.ee
更新日期：2004-07-01 00:00:00
abstract：:Genomewide scan, as shown by recently published linkage studies on the behavior of mice or in psychiatry, provides evidence for replicated quantitative trait loci (QTL). Several studies of Alzheimer's disease have demonstrated the promise of moving from clinical diagnoses to biological signs for psychiatric investigat...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1010222328509
更新日期：2001-01-01 00:00:00
abstract：:Recent studies have identified genes that influence the length of the circadian period maintained by mice housed under constant lighting conditions. However, a less studied circadian activity variable is the amplitude of daily oscillations in locomotor activity. This parameter reflects spontaneous activity exhibited u...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1021657800287
更新日期：1999-09-01 00:00:00
abstract：:The ε4 allele of the apolipoprotein (APOE) gene is a widely recognized genetic risk factor for developing Alzheimer's disease in older age. However, it is controversial whether there is a positive impact of the APOE ε4 allele on human cognitive performance in young adulthood, possibly representing a case of antagonist...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-019-09961-y
更新日期：2019-09-01 00:00:00
abstract：:The region containing ROBO1 (Chromosome 3p12.3) has been implicated as a susceptibility gene for reading disorder and language deficit by translocation and linkage data. No association studies have yet been reported supporting any candidate gene. Here we report the first association of this gene with language deficits...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-010-9402-9
更新日期：2011-01-01 00:00:00
abstract：:In a study designed to investigate genotype-environment interaction, eight strains of laboratory rats were crossbred in a replicated diallel cross employing infantile stimulation and its absence as environmental treatments. This paper reports on measures of the acquisition of two-way escape-avoidance conditioning, com...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01070816
更新日期：1981-07-01 00:00:00
abstract：:Here we provide a detailed description of the genome-wide information available on the National Longitudinal Study of Adolescent to Adult Health (Add Health) sibling pair subsample (Harris et al. in Twin Res Hum Genet 16:391-398, 2013). A total of 2,020 samples were genotyped (including duplicates) arising from 1946 A...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-014-9692-4
更新日期：2015-01-01 00:00:00
abstract：:The effect of the maternal environment on intermale aggression was studied by means of embryo transfer of genetically selected aggressive (SAL) and nonaggressive wild house mice (LAL), and their reciprocal F1's, to standard (NMR1) females. No effect was found on the attack latency scores (ALS), i.e., aggression: all g...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF02359756
更新日期：1996-09-01 00:00:00
abstract：:Chickens homozygous for the Dominant white or wild-type allele of PMEL17 were subjected to a broad phenotyping in order to detect consistent differences between genotypes. To exclude feather pecking, the chickens were individually housed without physical contact, from the day of hatching, and tested for social, aggres...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-010-9379-4
更新日期：2011-03-01 00:00:00
abstract：:In the original version of this article, unfortunately, in the acknowledgement section "National Institutes of Health (NIH, R37 AG033590-08) to J Cacioppo" was omitted. This has been corrected by publishing this erratum. ...
journal_title：Behavior genetics
pub_type： 已发布勘误
doi：10.1007/s10519-019-09956-9
更新日期：2019-05-01 00:00:00
abstract：:The heritability of human personality is well-established. Recent research indicates that nonadditive genetic effects, such as dominance and epistasis, play a large role in personality variation. One possible explanation for the latter finding is that there has been recent selection on human personality. To test this ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-012-9537-y
更新日期：2012-07-01 00:00:00
abstract：:Voluntary physical activity may be related to personality traits. Here, we investigated these relations in two mouse lines selectively bred for high voluntary wheel-running behavior and in one non-selected control line. Selection lines were more explorative and "information gathering" in the open-field test, either wi...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-010-9359-8
更新日期：2010-07-01 00:00:00
abstract：:This study uses longitudinal population-based samples of young siblings to examine the effects of two hypothesized moderators of early externalizing behaviors: parental emotional support and family socioeconomic status. The first sample, a twin sample from the Early Childhood Longitudinal Study-Birth Cohort (ECLS-B), ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-014-9664-8
更新日期：2014-09-01 00:00:00
abstract：:Selection for geotaxis was carried out with flies from a natural population of Drosophila melanogaster; geotactic behavior was measured by means of a Hirsch classification maze. The population was initally almost neutral to gravity, and it responded to both positive (downward) and negative (upward) selection with a re...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01065679
更新日期：1976-01-01 00:00:00
abstract：:A go/no-go operant task was used to assess the ability of male Long-Evans rats to discriminate between the urine odors from pairs of intact MHC congenic mice (C57BL/6-H-2Kb/J and C57BL/6-H-2Kbm1/ByJ), intact Y congenic mice (DBA1 and DBA1.C57BL10-Y), and castrated Y congenic mice of these two strains. The MHC congenic...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01082464
更新日期：1993-05-01 00:00:00
abstract：:Reading difficulties are both heritable and stable; however, little is known about the etiology of this stability. Results from a preliminary analysis of data from 56 twin pairs who participated in the Colorado Longitudinal Twin Study of Reading Disability (Astrom et al., Twin Res Hum Genet 10:434-439, 2007) suggested...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-011-9445-6
更新日期：2011-09-01 00:00:00
abstract：:Elucidating the causes of population divergence, and ultimately speciation, is a central objective of evolutionary biology. A number of previous studies of Drosophila populations from the Nahal Oren canyon (Mt Carmel, Israel) revealed significant interslope differences for a complex of fitness and behavioral traits. P...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-005-6119-2
更新日期：2005-11-01 00:00:00
abstract：:Variance components analysis provides an efficient method for performing linkage analysis for quantitative traits. However, power and type 1 error of variance components-based likelihood ratio testing may be affected when phenotypic data are nonnormally distributed (especially with high values of kurtosis) and there i...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/B:BEGE.0000013729.26354.da
更新日期：2004-03-01 00:00:00
abstract：:In previous electrophysiological experiments from hypopigmented animals (mice, rats, rabbits), single-unit recordings from both retinal ganglion axons and cells in the superior colliculus have demonstrated an increase in threshold in the dark-adapted state which is roughly proportional to the ocular melanin concentrat...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01067442
更新日期：1993-07-01 00:00:00
abstract：:Male Drosophila melanogaster from lines artificially selected to have divergent life histories were tested to determine if they differed in their effects on female reproductive behavior. During the first 5 days after mating, males from short-generation populations caused females to lay eggs at a faster rate than did m...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF02361157
更新日期：1996-01-01 00:00:00
abstract：:Twin studies are useful for assessing the relative importance of genetic or heritable component from the environmental component. In this paper we develop a methodology to study the heritability of age-at-onset or lifespan traits, with application to analysis of twin survival data. Due to limited period of observation...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-007-9150-7
更新日期：2007-07-01 00:00:00
abstract：:The amygdala integrates and coordinates emotional and autonomic responses. The genetics that underlie variation in amygdala structure may be coupled to variation in levels of aggression, fear, anxiety, and affiliated behaviors. We systematically quantified the volume and cell populations of the basolateral amygdala co...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-006-9122-3
更新日期：2007-01-01 00:00:00
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journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1025774716976
更新日期：2003-09-01 00:00:00
abstract：:Behaviors with high energetic costs may decrease in frequency in domestic animals as a response to selection for increased production. The aim of this study was to quantify production traits, foraging behavior, and social motivation in F2 progeny from a White Leghorn x red junglefowl intercross (n = 751-1046) and to p...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1020880211144
更新日期：2002-11-01 00:00:00
abstract：:In this study we analyzed the etiology of the relationship between personality traits and retrospectively recalled family environment. The data of 226 identical and 168 fraternal twin pairs reared together from the Jena twin study of social attitudes were available. Personality traits were measured using the self- and...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-008-9238-8
更新日期：2009-01-01 00:00:00
abstract：:This study documented the etiology contributions between anxiety symptoms (AS) and depressive symptoms (DS) from ages 6-12 years. Teachers assessed AS and DS in 1112 twins at 5 time points. A genetic cross-lagged model was used to estimate genetic/environmental contributions to cross-sectional, cross-age and cross-lag...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-019-09988-1
更新日期：2020-03-01 00:00:00
abstract：:The goal of the present study is to examine genetic and environmental influences on maternal and teacher ratings of Attention Problems (AP) in 7-year-old children. Teachers completed the Teacher Report Form (N=2259 pairs), and mothers the Child Behavior Checklist (N=2057 pairs). Higher correlations were found in twins...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-006-9084-5
更新日期：2006-11-01 00:00:00
abstract：:Males from the fifty selected generation of a selection program for aggressiveness in female Mus musculus (Ebert and Hyde, 1976) were tested to determine whether male aggressiveness showed a correlated response in selection for female aggressiveness. The results indicated that male aggression had not shown a correlate...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01065699
更新日期：1976-10-01 00:00:00
abstract：:Using high resolution magnetic resonance imaging data, we examined the interrelationships between eight cerebral lobar volumetric measures via both exploratory and confirmatory factor analyses in a large sample (N = 484) of pediatric twins and singletons. These analyses suggest the presence of strong genetic correlati...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-010-9332-6
更新日期：2010-03-01 00:00:00
abstract：:We investigated the extent to which performance on standardized achievement tests, executive function (EF), and aggression in childhood and adolescence accounted for the relationship between a polygenic score for educational attainment (EA PGS) and years of education in a community sample of African Americans. Partici...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-019-09982-7
更新日期：2020-01-01 00:00:00
