Abstract：
:Voluntary physical activity may be related to personality traits. Here, we investigated these relations in two mouse lines selectively bred for high voluntary wheel-running behavior and in one non-selected control line. Selection lines were more explorative and "information gathering" in the open-field test, either with increased upright positions or horizontal locomotion toward the middle ring. Furthermore, one of the selection lines had an increased risk-taking behavior relative to the control line in approaching a novel object placed in the center of the open field. However, anxiety behavior was increased in selection lines during the plus-maze test. Maze learning was not statistically different among lines, but routine behavior was increased in both selection lines when the maze exit after 2 days of testing was displaced. Specifically, in the displaced maze, selected mice traveled more frequently to the old, habituated exit, bypassing the new exit attached to their home cage. Although the generality of the results would need to be confirmed in future studies including all eight lines in the selection experiment, the increased routine and exploratory behavior (at least in the lines used in the present study) may be adaptive to sustain high activity levels.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Jónás I,Schubert KA,Reijne AC,Scholte J,Garland T Jr,Gerkema MP,Scheurink AJ,Nyakas C,van Dijk Gdoi
10.1007/s10519-010-9359-8subject
Has Abstractpub_date
2010-07-01 00:00:00pages
542-50issue
4eissn
0001-8244issn
1573-3297journal_volume
40pub_type
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