Abstract：
:Vagal influences on the heart were studied in narcotized cats, in which the cardiotropic effects of sympathetic nerves, heart rate, and pre- and afterload were excluded. Under these conditions vagus nerve exerted only a positive inotropic effect probably mediated by an unknown humoral factor.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Sheikh-Zade YRdoi
10.1007/BF02439260subject
Has Abstractpub_date
2000-04-01 00:00:00pages
335-6issue
4eissn
0007-4888issn
1573-8221journal_volume
129pub_type
杂志文章abstract：:Fragments of extracellular DNA are permanently released into the blood flow due to cell apoptosis and possible de novo DNA synthesis. To find out whether extracellular DNA can affect the synthesis of nitric oxide (NO), one of key vascular tone regulators, we studied in vitro effects of three artificial DNA probes with...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-010-0906-3
更新日期：2010-08-01 00:00:00
abstract：:Applications of cold and warm activated cellular immunity and orientation and exploratory behavior in mice. Application of cold increased the number of turns to the left in the open field, muscle force, and activity of the food instinct, and caused an increase in the total count of peripheral blood leukocytes. Warm ap...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-013-2052-1
更新日期：2013-04-01 00:00:00
abstract：:Hypoxia-induced immediate expression of transcription factor HIF-1α in the brain cortex is regulated by succinate produced in both the tricarbonic acid cycle and GABA shunt reactions and is induced by succinate-containing drugs. These facts prove the existence of succinate-dependent signalling regulation involved in i...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-018-3976-2
更新日期：2018-01-01 00:00:00
abstract：:A series of short neurotoxins (molecular weight 3500-5000 D) was isolated from Vietnamese scorpion B. occitanus sp. All these toxins blocked generation of action potentials (this effect depended on their molecular weight), but did not change conduction velocity and excitation threshold of the nerve. ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/a:1013659026064
更新日期：2001-10-01 00:00:00
abstract：:The effects of fullerene C(60) nanocomposites on human platelet aggregation induced by ADP, ristocetin, and collagen were studied. The nanocomposite containing fullerene C(60) in polyvinyl pyrrolidone solution did not change platelet aggregation, while fullerene C(60) in crown ether and Twin-80 solutions inhibited ADP...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-012-1592-0
更新日期：2012-03-01 00:00:00
abstract：:Here we present the results of histochemical detection of 3β-hydroxysteroid dehydrogenase in neurons of the neocortex, cerebellum, and brainstem. The positive reaction was observed in a low number of neocortical, midbrain, and pontine neurons. The maximum number of positive neurons was detected in the cerebellar corte...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-012-1532-z
更新日期：2012-01-01 00:00:00
abstract：:Agonists of glutamate ionotropic (NMDA) and metabotropic receptors (mGluRI and mGluRIII) had the regulatory effect on ADP-ribosyl cyclase/CD38 activity in cerebellar granular cells of newborn rats. Perinatal hypoxic-ischemic brain injury was followed by dysregulation of this mechanism. ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-011-1196-0
更新日期：2011-03-01 00:00:00
abstract：:Leprosy was modeled in an experiment on BALB/c, BALB/cNude, CBA, and C57BL/6ТNF-/- mice using three Mycobacterium leprae strains obtained from patients with a diagnosis of A30 according to ICD-10 from different regions of the Russian Federation. Proliferation of M. leprae of the used strains showed a temporal-quantita...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-020-04991-7
更新日期：2020-10-01 00:00:00
abstract：:New methods of restriction fragment length polymorphism analysis were developed to distinguish polymorphic variants C190T, G191A, G857A, and 859Del of the NAT2 gene located close to each other. ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-009-0309-5
更新日期：2008-10-01 00:00:00
abstract：:The effect of serotoninotropic substances with positive and negative effects on serum concentrations of thyrotropic hormone, total triiodothyronine, and total thyroxin was studied in old male rats. Chronic treatment with L-tryptophan and citalopram reduced serum level of total thyroxin in old intact animals and serum ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-010-0824-4
更新日期：2009-11-01 00:00:00
abstract：:Efficiency and mechanisms of action of photodynamic therapy of M-1 sarcoma were studied experimentally on rats using photodithazine, a novel chlorine photosensitizer. The tissue and cellular targets for this agent are vascular wall, plasma membrane of tumor cells, and intracellular structures responsible for prolifera...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-005-0133-5
更新日期：2004-12-01 00:00:00
abstract：:Maximum magnetic resonance artifacts from stents are often determined by the presence of ferromagnetic compounds in the delivery system. We propose a mathematic model describing artifacts caused by nitinol stents. A method for evaluation of critical radial rigidity of the stents was developed. ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-007-0356-8
更新日期：2007-09-01 00:00:00
abstract：:The author name G. A. Chastikina should read G. A. Chastikin. ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章,已发布勘误
doi：10.1007/s10517-017-3883-y
更新日期：2017-09-01 00:00:00
abstract：:Therapy of rats with CCl4 hepatitis with Stellaria media L. water-soluble polysaccharide fraction in a dose of 100 mg/kg reduces serum activities of transaminases (ALT and AST), alkaline phosphatase, bilirubin, and the thymol test values. In the liver, the density of inflammatory infiltration of the organ parenchyma, ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-013-2021-8
更新日期：2013-03-01 00:00:00
abstract：:Oxidized dextran is suggested for prevention of infection induced by influenza A/H5N1 viruses, methods of its use and doses are determined. Two intravenous injections of dextran 3 and 1 days before experimental infection of outbred mice by influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus resulted in a high preven...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-014-2704-9
更新日期：2014-11-01 00:00:00
abstract：:The effects of intranasal pretreatment with antibodies against glutamate on focal penicillin-induced epileptic activity were studied by recording electrocorticogram in non-anesthetized freely moving male Wistar rats. Anticonvulsant effects of intranasal administration of anti-glutamate antibodies (300 μg/kg) 1 h befor...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-013-2206-1
更新日期：2013-09-01 00:00:00
abstract：:We studied the interaction between the sympathetic and parasympathetic parts of the autonomic nervous system in the regulation of smooth muscles in the femoral artery and trachea. It was shown that this regulation involves ganglionic serotoninergic neurons transmitting excitation to 5-HT, receptors in the effector tis...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-006-0078-3
更新日期：2006-01-01 00:00:00
abstract：:The incidence of mutations in the BRCA1 and BRCA2 genes in the studied sampling of 74 patients with ovarian cancer was 19%. The incidence of mutations in the Russian sampling of patients, formed without consideration for the family history, is one of the highest in European countries. Retrospective analysis showed tha...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-007-0261-1
更新日期：2007-07-01 00:00:00
abstract：:We proposed a new indicator for evaluation of functional activity of Ca(2+) in human blood serum based on lysis of sheep erythrocytes with 10% human blood serum in the presence of 0.55 mM ethylene glycol tetraacetic acid at 37°C for 10 min. After incubation, the degree of sheep erythrocytes lysis inhibition is estimat...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-015-2948-z
更新日期：2015-07-01 00:00:00
abstract：:The rates of oxyhemoglobin drop and CO(2) release in dogs with magnetized and nonmagnetized blood were compared. Stationary magnetic field enhances blood oxygen capacity by no less than 24%. A hypothesis was proposed on formation of bioxyhemoglobin molecules under the effect of magnetic field, in which hem binds two O...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/a:1017523407969
更新日期：2001-02-01 00:00:00
abstract：:Study of the epidermocyte nuclear-nucleolar system in atopic dermatitis and lichen planus by computer morphometry of preparations stained with 50% AgNO3 showed an increase in their morphometric parameters, reflecting hyperregeneratory processes. ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-007-0336-z
更新日期：2007-09-01 00:00:00
abstract：:Antiaggregant activity of a new tricyclic benzimidazole derivative, RU-891 compound, was studied on the model of ADP-induced platelet aggregation in vitro and intravascular platelet aggregation in vivo. We evaluated the effect of this substance on blood coagulation potential. Antiaggregant agent acetylsalicylic acid w...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-014-2453-9
更新日期：2014-04-01 00:00:00
abstract：:The molecular mechanism of atherosclerosis is based on decreased expression of signal molecules connexin (Cx37 and Cx40), vascular endothelial growth factor (VEGF), and proliferative protein Ki-67, which characterize the processes of cell-cell interactions and proliferation of vascular endotheliocytes. Lys-Glu-Trp pep...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-014-2556-3
更新日期：2014-07-01 00:00:00
abstract：:Glycine stabilizes energetics of brain mitochondria under conditions of brain hypoxia in vivo modeled by ligation of the common carotid artery in rats. Hypoxia reduced respiratory control in brain cortex mitochondria from 7.7 ± 0.5 to 4.5 ± 0.3. Preliminary oral administration of glycine almost completely prevented th...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-012-1638-3
更新日期：2012-05-01 00:00:00
abstract：:The efficiency of ascorbate and alpha-tocopherol as stabilizers of beta-carotene, which is widely used in complex therapy and prevention of some diseases accompanied by oxidative stress, was studied. The latency of induced beta-carotene oxidation linearly depends on ascorbate concentration, while steady-state rate non...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/BF02682099
更新日期：2000-07-01 00:00:00
abstract：:Voltage clamp and concentration jump experiments performed on Purkinje cells isolated from rat cerebellum showed that novel imidazobenzoimidazole derivative RU-353 increased the amplitude of GABA-activated chlorine current in a dose-dependent manner (EC50=15 microM for the currents activated by 1 microM GABA). RU-353 ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-005-0481-1
更新日期：2005-09-01 00:00:00
abstract：:We studied the role of carbon monoxide (CO) in the effect of P2X and P2Y receptor agonist ATP on the tone of rat aorta segments with intact endothelium. ATP (1-1000 μM) and P2X receptor agonist α,β-MeATP (100 μM) relaxed segments precontracted with phenylephrine (10 μM), while UTP (100-1000 μM) increased the amplitude...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-019-04527-8
更新日期：2019-07-01 00:00:00
abstract：:Antibodies to cyclophosphamide obtained by homeopathic potentiation and administered in ultralow doses exhibit no antiblastic activity and did not modulate the effectiveness of cyclophosphamide during antitumor therapy of animals with transplanted tumors (Lewis lung carcinoma and Ehrlich adenocarcinoma). ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/a:1024722528171
更新日期：2003-01-01 00:00:00
abstract：:Peculiarities of skin extension under vacuum applicators (nozzles) of various design was studied in 20 volunteers aged 18-25 years. The data obtained made it possible to chose optimal parameters of elastic membranes of the vacuum cups that produce stretch sufficient for vacuum-membrane skeletal muscle extension with m...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/a:1015550922784
更新日期：2002-02-01 00:00:00
abstract：:We studied the effects and mechanisms of action of NaHS, an H2S donor, on isolated phenylephrine-precontracted bovine mesenteric lymph nodes. NaHS induced concentration-dependent relaxation of lymph nodes. Removal of the endothelium reduced, but did not abolish the relaxing effect of NaHS. The relaxing effect was redu...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-020-04848-z
更新日期：2020-06-01 00:00:00
