Centrosome structure and microtubule nucleation in animal cells.

Abstract:

:Genetic studies in the budding yeast have led to the molecular characterization of gamma-tubulin associated proteins and to the identification of orthologues in animal cells. While the gamma-tubulin complex is more complex in animal cells than in budding yeast, its function is probably maintained throughout evolution. In this review we discuss some of the possible regulations of the nucleation activity in the light of the centrosome structure. A potential cross-talk between microtubule nucleation and centrosome duplication is suggested by some, still scarce, data.

journal_name

Biol Cell

journal_title

Biology of the cell

authors

Tassin AM,Bornens M

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

343-54

issue

4-5

eissn

0248-4900

issn

1768-322X

journal_volume

91

pub_type

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