Despite its high representation in extrachromosomal circular DNAs from Drosophila embryos, the dodecasatellite does not allow autonomous replication in cultured cells.

Abstract:

:The dodecasatellite is a 11/12 bp tandemly repeated sequence which is overrepresented, with regard to its genomic representation, in extrachromosomal circular DNAs from D melanogaster embryos. Here we show that a bacterial plasmid carrying a cluster of dodecasatellite is not able to replicate efficiently in cultured cells. This observation does not support the hypothesis that the overrepresentation results from an autonomous replication of dodecasatellite circular DNA molecules.

journal_name

Biol Cell

journal_title

Biology of the cell

authors

Renault S,Degroote F,Picard G

doi

10.1016/0248-4900(93)90262-d

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

51-4

issue

1

eissn

0248-4900

issn

1768-322X

journal_volume

79

pub_type

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