The p53 target gene TRIM22 directly or indirectly interacts with the translation initiation factor eIF4E and inhibits the binding of eIF4E to eIF4G.

abstract：:Human pancreatic ductal cells of the Capan 1 cell line differentiate progressively during growth. After the exponential growth phase, the cells elongate and become polarized with their apical poles covered by microvilli and separated from the basolateral pole by tight junctions. In this stationary phase, they form dom...

journal_title：Biology of the cell

authors： Mahieu I,Becq F,Wolfensberger T,Gola M,Carter N,Hollande E

更新日期：1994-01-01 00:00:00

abstract：:An interaction between human poly(A)-binding protein (PABP) et human eRF3 has been demonstrated using a double-hybrid approach and in vitro assays. Here, we show that the binding of both proteins is conserved through evolution. We also demonstrate that the last 39 C-terminal amino acids of PABP contain the interface t...

journal_title：Biology of the cell

authors： Cosson B,Berkova N,Couturier A,Chabelskaya S,Philippe M,Zhouravleva G

更新日期：2002-09-01 00:00:00

abstract：:Separation by velocity sedimentation at unit gravity according to the STAPUT system of Miller and Phillips was applied to a population of rabbit megakaryocytes previously enriched by density gradient centrifugation. By this means, 80,000 to 100,000 megakaryocytes with 100% purity were collected in eight fractions acco...

journal_title：Biology of the cell

authors： Dupont H,Dupont MA,Bricaud H,Boisseau MR

更新日期：1983-01-01 00:00:00

abstract：:Tensins are focal adhesion molecules that were identified and characterised in the late 1980s to early 1990s. They play an essential role in the control of cell adhesion. Tensins can bind the tail of ß integrin via their phospho tyrosine binding domain, they exhibit various protein interaction domains including a Src ...

journal_title：Biology of the cell

authors： Blangy A

更新日期：2017-03-01 00:00:00

abstract：:The PAS-positive-calcium-sensitive (Ca-s) cells of the pars intermedia (PI) were studied in goldfish kept in fresh water (FW), deionized water (DW), 1/3 sea water (SW) and 1/3 Ca-free SW. Ultrastructural studies show that Ca-s cells of control goldfish kept in FW have a low activity with elongated or deeply indented n...

journal_title：Biology of the cell

authors： Olivereau M,Chambolle P,Dubourg P

更新日期：1983-01-01 00:00:00

abstract：:The oligochaete annelids, belonging to the subfamily Tubificinae, produce two types of spermatozoa: eusperm (the fertilising ones) and parasperm, protecting and carrying the eusperm. The pathway for the production of the two types is common until the onset of meiosis, but then a regular meiosis produces eusperm, where...

journal_title：Biology of the cell

authors： Ferraguti M,Fascio U,Boi S

更新日期：2002-05-01 00:00:00

abstract：:Bovine tracheal gland (BTG) cells in culture show an epithelial-fibroblastoid transition after several passages. To investigate these BTG cell phenotype changes, we studied the effects of both the culture medium and passage number on the expression of epithelial cytoskeletal proteins and glandular serous cell markers....

journal_title：Biology of the cell

authors： Benali R,Dupuit F,Chevillard M,Jacquot J,Haye B,Puchelle E

更新日期：1991-01-01 00:00:00

abstract：:In mature ciliated cells, the basal feet associated to the basal bodies point out in the direction of the effective stroke of the ciliary beating. In contrast, during ciliogenesis, the basal feet of the newly anchored basal bodies are randomly oriented. The reorientation of basal bodies occurs during the beginning of ...

journal_title：Biology of the cell

authors： Boisvieux-Ulrich E,Laine MC,Sandoz D

更新日期：1985-01-01 00:00:00

abstract：:Background information. Transport of water and small neutral solutes across plasma membranes is facilitated by AQP (aquaporin) and aquaglyceroporin channels, which belong to the MIP (major intrinsic protein) family. So far, more than 800 MIP proteins have been identified on the basis of sequence homology, but only les...

journal_title：Biology of the cell

authors： Hubert JF,Duchesne L,Delamarche C,Vaysse A,Gueuné H,Raguénès-Nicol C

更新日期：2005-09-01 00:00:00

abstract：:Toad bladder epithelial cells were homogenized and fractionated by Percoll density-gradient centrifugation. Binding of tritium-labeled vasopressin ([3H]AVP) was measured in surface membranes (SM), microsomes (M), and a 100,000 g (60-min) microsomal supernatant fraction (S). More than two-thirds of the total receptors ...

journal_title：Biology of the cell

authors： Eggena P,Ma CL

更新日期：1989-01-01 00:00:00

abstract：:Image cytometry was applied to study the intracellular localization of autofluorescence and the influence of an oxidative stress on this emission. K562 erythroleukemia cancer cells were analyzed with a microspectrofluorometer, coupled with a Argon laser (Ar+) (363 nm). From each cell, 15 x 15 emission spectra were rec...

journal_title：Biology of the cell

authors： Bondza-Kibangou P,Millot C,Dufer J,Millot JM

更新日期：2001-11-01 00:00:00

abstract：:Immunofluorescent techniques have been used in the analysis of DNA-RNA hybrids occurrence and its relationship to transcriptional events on polytene chromosomes of Drosophila subobscura. We have studied the distribution of these hybrids on uninduced/induced chromosomes. Two different indirect immunofluorescence method...

journal_title：Biology of the cell

authors： Arbona M,Cuenca JB,de Frutos R

更新日期：1992-01-01 00:00:00

abstract：:Image analysis was used to study the repair process of a circular mechanical lesion of confluent human endothelial cells in culture after irradiation (10 Gy) prior to wounding. Coverage of denuded areas 48 and 96 h after injury of endothelial cells was identical in control and irradiated cultures, although the labelin...

journal_title：Biology of the cell

authors： Klein-Soyer C,Beretz A,Cazenave JP,Driot F,Maffrand JP

更新日期：1990-01-01 00:00:00

abstract：:The entry into, and exit from, mitosis are controlled by a universal M-phase promoting factor (MPF) composed of at least p34cdc2 and a cyclin. Embryonic systems are convenient for studying the association and dissociation of the active MPF complex because oocytes and eggs are naturally arrested at a specific point of ...

journal_title：Biology of the cell

authors： Charbonneau M,Grandin N

更新日期：1992-01-01 00:00:00

abstract：:Retinitis pigmentosa (RP) is a heterogeneous group of inherited retinal degenerative diseases, characterized by the progressive death of rod and cone photoreceptors. A tremendous genetic heterogeneity is associated with the RP phenotype. Most mutations affect rods selectively and, through an unknown pathway, cause the...

journal_title：Biology of the cell

authors： Delyfer MN,Léveillard T,Mohand-Saïd S,Hicks D,Picaud S,Sahel JA

更新日期：2004-05-01 00:00:00

abstract：:A quantitative ultrastructural study was performed on 56 ejaculates showing anomalies of the sperm axonemal complex. The anomalies comprised either the absence of one, or more often several, axonemal structures, or defective elongation of the doublets. Several characteristics relating to the extent and superimposition...

journal_title：Biology of the cell

authors： Escalier D,David G

更新日期：1984-01-01 00:00:00

abstract：:Primary cultures of cells from breast carcinomas were attempted in 74 cases. Growth was observed in 46 cases. Using immunochemical demonstration of keratin proteins (KER), epithelial membrane antigen (EMA) and carcinoembryonic antigen (CEA), three morphologically distinct cell populations were characterized and descri...

journal_title：Biology of the cell

authors： Muller D,Fricker JP,Millon-Collard R,Abecassis J,Pusel J,Eber M,Methlin G

更新日期：1987-01-01 00:00:00

abstract：:Interaction of sperm and egg at fertilization induces well-coordinated molecular events including specific recognition between species, adhesion and fusion, that lead to the formation of a zygote, a totipotent cell that develops into a new individual. A calcium signal, common to a great number of species, from marine ...

journal_title：Biology of the cell

authors： Ciapa B,Chiri S

更新日期：2000-07-01 00:00:00

abstract：:Flow cytometry has important advantages over conventional techniques. It is rapid, highly sensitive and allows multi-parametric analysis and cell sorting. Potential exists for the measurement of many cell functions by flow cytometry. The technique can be used to determine cell viability, intracellular calcium and pH, ...

journal_title：Biology of the cell

authors： Maftah A,Huet O,Gallet PF,Ratinaud MH

更新日期：1993-01-01 00:00:00

abstract：:During wound-healing in cultured frog skin fragments, fibronectin (FN) was detected in the dermal-epidermal junction. Intracellular fibronectin was stained using permeabilization and DAB immunoperoxidase. With electron microscopy intracytoplasmic FN granules were localized in the epidermal processes of the stratum ger...

journal_title：Biology of the cell

authors： Denefle JP,Zhu QL,Lechaire JP

更新日期：1989-01-01 00:00:00

abstract：:When mouse peritoneal macrophages were made to adhere firmly on glass surface and then removed by sequential treatment with hypotonic triethanolamine and Nonidet P-40, a set of proteins were found to be left behind at the sites of adherent cells. Such glass-adherent proteins were detected as round or ellipsoidal patch...

journal_title：Biology of the cell

authors： Tomita M,Ishikawa H

更新日期：1992-01-01 00:00:00

abstract：:We have characterized the selectivity filter of the water channel aquaporin-1 (AQP1) of proximal straight tubules (PST), as an equivalent cylindrical structure with a diameter of approximately 4.5 A, where water molecules single file. We report here efforts to evaluate its length. PST were dissected from rabbit kidney...

journal_title：Biology of the cell

authors： Whittembury G,González E,Gutiérrez AM,Echevarría M,Hernández CS

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND INFORMATION:Proliferating cell nuclear antigen (PCNA) is a key component of the DNA replication machinery involved in the process of DNA elongation, recombination, methylation and repair. We have used PCNA fused with green fluorescent protein (GFP-PCNA) as a convenient tool to show the progress of S-phase in...

journal_title：Biology of the cell

authors： Kisielewska J,Lu P,Whitaker M

更新日期：2005-03-01 00:00:00

abstract：:Much remains to be learned about how cancer cells acquire the property of migration, a prerequisite for invasiveness and metastasis. Loss of p53 functions is assumed to be a crucial step in the development of many types of cancers, leading to dysregulation of cell cycle checkpoint controls and apoptosis. However, emer...

journal_title：Biology of the cell

authors： Roger L,Gadea G,Roux P

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:The translocase of the mitochondrial inner membrane (TIM) imports most of the nucleus-encoded proteins that are destined for the matrix, inner membrane (IM) and the intermembrane space (IMS). Trypanosoma brucei, the infectious agent for African trypanosomiasis, possesses a unique TIM complex consisting of se...

journal_title：Biology of the cell

authors： Singha UK,Tripathi A,Smith JT Jr,Quinones L,Saha A,Singha T,Chaudhuri M

更新日期：2020-10-20 00:00:00

abstract：:Brain intricacies and the difficulty that scientists encounter in revealing its function with standard approaches such as electrical stimulation of neurons have led to the exploration of new tools that enable the study of neural circuits in a remote and non-invasive way. To this end, optogenetics has initialised a rev...

journal_title：Biology of the cell

authors： Papagiakoumou E

更新日期：2013-10-01 00:00:00

abstract：:A history of the early development of the confocal laser scanning microscope in the MRC Laboratory of Molecular Biology in Cambridge is presented. The rapid uptake of this technology is explained by the wide use of fluorescence in the 80s. The key innovations were the scanning of the light beam over the specimen rathe...

journal_title：Biology of the cell

authors： Amos WB,White JG

更新日期：2003-09-01 00:00:00

abstract：:Peroxisomes are present in most eukaryotic cell types, and have different enzymatic content and metabolic functions throughout the life scale. The endosymbiotic origin of these DNA-devoid organelles is supported by evolutionary data concerning genes encoding not only most peroxisomal proteins, but also several transcr...

journal_title：Biology of the cell

authors： Latruffe N,Vamecq J

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND INFORMATION:Caspases are cysteine proteases that mediate apoptosis (programmed cell death) initiation and execution. Apoptosis is a conserved mechanism shared by all metazoans, although its physiological function and complexity show considerable taxon-dependent variations. To gain insight into the caspase re...

journal_title：Biology of the cell

authors： Weill M,Philips A,Chourrout D,Fort P

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND INFORMATION:The role of the LIM-domain-containing protein Ajuba was initially described in cell adhesion and migration processes and recently in mitosis as an activator of the Aurora A kinase. RESULTS:In the present study, we show that Ajuba localizes to centrosomes and kinetochores during mitosis. This loc...

journal_title：Biology of the cell

authors： Ferrand A,Chevrier V,Chauvin JP,Birnbaum D

更新日期：2009-04-01 00:00:00