Abstract:
RATIONALE AND OBJECTIVES:This study was conducted to determine whether significant reduction in radiation dose (250 mAs-->50 mAs), in chest computed tomography (CT) using volume acquisition affects image quality or the detectability of pathologic findings in the lung and mediastinum. METHODS:Phantom studies were conducted to evaluate resolution and noise level, then a patient study was then done. Fifty consecutive patients (10 normal and 40 abnormal) cases were examined. After a scan (250 mAs, 120OkVp) of the entire thorax, five additional slices (50 mAs, 120kVp) at the level of the abnormality were obtained. Three independent observers evaluated the visibility of normal lung and mediastinal structures, as well as image noise. The mean score was compared between the standard and low doses. In a second study, an independent evaluation of the presence or absence of pathologic findings was made by four observers. RESULTS:Lucite phantom studies demonstrated diminished low-contrast resolution and increased noise level for the low-dose technique. Observers assessed more noise in the low-dose images (P < 0.001). The normal structures were judged to be more visible with standard dose (P < 0.01), but the magnitude of the judged differences was small especially in the lung. No differences were found in the detection of lung and mediastinal abnormalities (P > 0.10). CONCLUSIONS:The low-dose technique was effective in demonstrating pathologic findings for the lung and mediastinum. Low-dose spiral CT should be considered as a viable alternative to standard-dose spiral CT.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Takahashi M,Maguire WM,Ashtari M,Khan A,Papp Z,Alberico R,Campbell W,Eacobacci T,Herman PGdoi
10.1097/00004424-199802000-00002subject
Has Abstractpub_date
1998-02-01 00:00:00pages
68-73issue
2eissn
0020-9996issn
1536-0210journal_volume
33pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:To analyze changes in Doppler ultrasound variables of the portal vein in relation to liver biopsy findings, the authors performed a prospective study of 316 Doppler ultrasound examinations in the first 2 weeks after orthotopic liver transplantation on 23 patients. METHODS:Recordings were obtai...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199612000-00007
更新日期:1996-12-01 00:00:00
abstract::The large intestines of eight boxer dogs with canine histiocytic ulcerative colitis (CHUC) and 10 normal dogs were studied by in vivo angiography and postmortem microangiography. The vascular abnormalities were correlated with the gross and histologic pathology found at necropsy. The angiographic abnormalities were ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197505000-00005
更新日期:1975-05-01 00:00:00
abstract:OBJECTIVES:This clinical study investigated the pharmacokinetics and safety of gadobutrol, a magnetic resonance (MR) imaging extracellular contrast agent, in pediatric patients aged 2 to 17 years. MATERIALS AND METHODS:In this open-label, multicenter study, patients scheduled for routine contrast-enhanced MR imaging o...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181bfe2d2
更新日期:2009-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:In contrast-enhanced dual-energy subtraction imaging 2 images acquired postcontrast media administration at different energies are subtracted to highlight structures hidden in the absence of contrast media. X-ray spectra of the newly developed digital full-field mammography units (GE Senographe...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.RLI.0000077124.24140.bd
更新日期:2003-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To improve the accuracy of magnetic resonance imaging (MRI) in evaluating the response of osteosarcomas to preoperative chemotherapy, the authors developed a technique of mapping tumor necrosis and viability by quantitating slope values of gadolinium-DTPA (Gd-DTPA) uptake on dynamic fast low-an...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199205000-00010
更新日期:1992-05-01 00:00:00
abstract::Various water soluble contrast media (WSCM) were injected subcutaneously into 970 hind feet of 485 rats. Gross morphologic changes were seen after the injection and analyzed as a function of various physicochemical characteristics of WSCM. The WSCM of larger volume, higher osmolality, higher iodine content, and meglum...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199006000-00011
更新日期:1990-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To compare technical aspects and neointima formation of a new Nitinol stent and a Wallstent. METHODS:A Nitinol sten and a Wallstent were placed into the iliac arteries of 14 sheep (total of 28 stents) and followed angiographically. Seven sheep were killed after 1 month and 7 after 4.5 months. ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199507000-00004
更新日期:1995-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To characterize the long-term effects of therapeutic doses of ionizing radiation on the uptake and distribution of percutaneously delivered particulate contrast media in normal lymph nodes. METHODS:Two milliliters of an iodinated nanoparticle suspension (76 mg I/mL) was injected subcutaneously...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200003000-00007
更新日期:2000-03-01 00:00:00
abstract:PURPOSE:We sought to evaluate the potential of dynamic contrast enhancement after the intravenous administration of an iodine-based contrast medium in full-field digital mammography. MATERIAL AND METHODS:A protocol for image acquisition was established for contrast-enhanced mammography and the mammography unit (Senogr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000167421.83203.4e
更新日期:2005-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the efficacy of oral administration of cilostazol, an antithrombotic agent, for the prevention of thrombotic occlusion and intimal hyperplasia after stenting. METHODS:Single-bodied Z-stents were placed in the iliac arteries of 23 dogs. Before stenting, an embolizing coil was introd...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199509000-00004
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVES:Multidetector-row computed tomography coronary images are usually analyzed in mid-diastole (MD). Because of slow coronary motion also in end-systole (ES), we evaluated the impact on image quality of including ES images and defined an efficient reconstruction protocol. MATERIAL AND METHODS:In 50 coronary mul...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000153930.34439.e4
更新日期:2005-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of the study was to examine the effects of azelastine on proliferation, clonogenic activity, cell-cycle, and migration of human aortic smooth-muscle cells (haSMCs) in vitro. METHODS:HaSMCs were treated for 4 days with azelastine (1 micromol/L, 25 micromol/L, 50 micromol/L). Half of the...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200205000-00002
更新日期:2002-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study evaluated the value of dynamically enhanced fast low-angle shot (FLASH) magnetic resonance (MR) imaging in measuring cardiac output with and without dipyridamole pharmacological stress. METHODS:Ten subjects underwent rest and stress MR imaging. Rest images were acquired using electr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199611000-00003
更新日期:1996-11-01 00:00:00
abstract:PURPOSE:Magnetic Resonance Imaging (MRI) has become the method of choice in the evaluation of patients with suspected cervical artery dissection (CAD). However, reliable identification of acute CAD might be impaired by the limited spatial resolution of standard 1.5 T MRI. In this preliminary study, we implemented a mul...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000195836.57778.1f
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to optimize computed tomography (CT) surveillance of skeletal metastases in patients with breast cancer through the use of osseous subtraction maps between baseline and follow-up examinations created by a novel software algorithm. The new postprocessing algorithm segments the origina...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000343
更新日期:2017-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Ultrasound can cause destruction of microbubble contrast agents used to enhance medical ultrasound imaging. This study sought to characterize the dynamics of this interaction by direct visual observation of microbubbles during insonification in vitro by a medical ultrasound imaging system. MET...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199812000-00004
更新日期:1998-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study assesses the ability of a cardiac-gated phase-contrast magnetic resonance imaging (MRI) technique to measure renal blood flow (RBF) noninvasively in humans. METHODS:In nine normal volunteers, total RBF in the renal arteries and in the left renal vein was estimated by MRI and correla...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199206000-00012
更新日期:1992-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:To estimate the sensitivity to find small coronary artery calcium lesions with use of different slice widths with electron beam tomography. MATERIALS AND METHODS:Two studies were performed. Study 1 utilized double scanning of a stationary cork phantom with three different slice thickness (1.5, ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.RLI.0000055289.97726.B1
更新日期:2003-03-01 00:00:00
abstract::A nonionic contrast medium (iohexol) was evaluated for safety and efficacy in pediatric angiocardiography in this study of 15 patients, age 6 to 82 months. Patients carried a preliminary diagnosis of congenital heart disease. Subjects were injected with iohexol, 350 mg iodine/ml of solution with an average volume of 2...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to conduct a radiopathologic evaluation of right-angled traction bronchiectasis to differentiate idiopathic pulmonary fibrosis (IPF) without honeycombing from idiopathic nonspecific interstitial pneumonia (NSIP). MATERIALS AND METHODS:The derivation cohort included 78 consecutive p...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000651
更新日期:2020-06-01 00:00:00
abstract::The interdisciplinary approach to medical education has often been deficient in medical school curricula. Because of the nonintegrated approach to medical education, problem solving capabilities are not fostered. The clinical presentation of a patient, the imaging modalities used to investigate the patient, and the ul...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198604000-00015
更新日期:1986-04-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the feasibility of a prototype volume-interpolated breath-hold examination (VIBE) sequence using compressed sensing (VIBECS) for rapid multiphase arterial magnetic resonance imaging (MRI) at different temporal resolution during free-breathing in comparison with a convention...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000459
更新日期:2018-10-01 00:00:00
abstract::At a given radiation dosage and field of view, five variables are under meaningful control for intravenous digital subtraction angiography (IV-DSA): concentration and quantity of contrast media injected, volume of injectate, rate of injection, and site of injection. Some controversy exists regarding the selection of a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198401000-00007
更新日期:1984-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Because of the greatly increased cost of nonionic, low-osmolar contrast material, some practitioners reserve its use for patients at high risk for an adverse contrast reaction. The authors attempt to evaluate the proportion of low-risk outpatients--when offered a choice between the more expensi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199304000-00008
更新日期:1993-04-01 00:00:00
abstract:OBJECTIVES:We compared the image quality and diagnostic performance of 2 fat-suppression methods for black-blood T2-weighted fast spin-echo (FSE), which are as follows: (a) short T1 inversion recovery (STIR; FSE-STIR) and (b) spectral adiabatic inversion recovery (SPAIR; FSE-SPAIR), for detection of acute myocardial in...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182718672
更新日期:2013-01-01 00:00:00
abstract::A high-speed computed tomography (CT) scanner was used for measuring flow in a phantom and in the common carotid arteries of six dogs. The general ability of the scanner to assess flow using contrast media boluses was tested with the phantom. The validated simple concept was then used in the animals. The carotid blood...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198712000-00008
更新日期:1987-12-01 00:00:00
abstract::Analysis of 46 sacroiliac joints removed in toto at random during routine autopsies was undertaken to define the pathologic and radiographic alterations of this joint in middle-aged and elderly patients. Each joint was sectioned, photographed and radiographed and large microscopic slides were prepared. Sacroiliac oste...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197511000-00008
更新日期:1975-11-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to assess the discriminative performance of quantitative multiparametric magnetic resonance imaging (mpMRI) between prostate cancer and noncancer tissues and between tumor grade groups (GGs) in a multicenter, single-vendor study, and to investigate to what extent site-specific dif...
journal_title:Investigative radiology
pub_type: 杂志文章,多中心研究
doi:10.1097/RLI.0000000000000558
更新日期:2019-07-01 00:00:00
abstract::The study aim was to define potential differences and advantages in magnetic resonance (MR) patterns of tumoral contrast enhancement using either a small molecular, extracellular fluid contrast enhancer [Gd-DTPA] or a macromolecular agent [albumin-(Gd-DTPA)20], designed for primary intravascular biodistribution. MR im...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198908000-00007
更新日期:1989-08-01 00:00:00
abstract:OBJECTIVES:Volumetric magnetic resonance (MR)-guided high-intensity focused ultrasound (HIFU) is a completely noninvasive image-guided thermal ablation technique. Recently, there has been growing interest in the use of MR-HIFU for noninvasive ablation of malignant tumors. Of particular interest for noninvasive ablation...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182820257
更新日期:2013-06-01 00:00:00