Evaluation of anti-cardiolipin antibody and its cross-reactivity in sera of patients with lepromatous leprosy.

abstract：:Centromere protein B (CENP-B), which is an alphoid DNA binding protein, is the target antigen in autoimmune disease patients (often those with scleroderma). In this study, we analysed activities of anti-CENP-B-DNA complex in anticentromere antibody (ACA)-positive patients using DNA immunoprecipitation with purified CE...

journal_title：Archives of dermatological research

authors： Muro Y,Matsumoto Y,Ohashi M

更新日期：1992-01-01 00:00:00

abstract：:An ultrastructural study of the skin lesion of a young patient affected by pseudo-Kaposi's sarcoma of the Bluefarb-Stewart type (BSS) is reported. The neoplasm consisted of a proliferation of vascular structures mostly consisting of a solid bud of endothelial cells surrounded by a thinned and polystratified basement m...

journal_title：Archives of dermatological research

authors： Fimiani M,Simoni S,Miracco C,De Santi M,Luzi P,Andreassi L

更新日期：1989-01-01 00:00:00

abstract：:The treatment of drug-induced toxic epidermal necrolysis (TEN) remains unsatisfactory. Intravenous immunoglobulins (IVIg) and intravenous cyclosporin A (CsA) have shown some efficacy in short series of patients. We assessed the effects of IVIg and CsA on TEN lesional and apparently uninvolved skin using standard histo...

journal_title：Archives of dermatological research

authors： Paquet P,Jacob E,Damas P,Pirson J,Piérard G

更新日期：2005-12-01 00:00:00

abstract：:We have observed that lipopolysaccharide (LPS) induces pigmentation in melanocytes and in this study have examined whether these responses are mediated by the p38 mitogen-activated protein kinase (MAPK) signaling pathway. LPS appears to stimulate the pigmentation of melanocytes and cultured skin. LPS was found to indu...

journal_title：Archives of dermatological research

authors： Ahn JH,Jin SH,Kang HY

更新日期：2008-07-01 00:00:00

abstract：:The goal of this study is to investigate commercially available cosmetics (foundations, skin care creams) which also claim to include a sun protection factor (SPF). Are these products, which are not considered sunscreen products, helpful or could they be harmful? Using an in vitro method, we tested the effectiveness o...

journal_title：Archives of dermatological research

authors： Séhédic D,Hardy-Boismartel A,Couteau C,Coiffard LJ

更新日期：2009-09-01 00:00:00

abstract：:Oxidative stress may play a pivotal role in the pathogenesis of psoriasis, an inflammatory/hyperproliferative skin disease characterized by the cutaneous accumulation of neutrophils releasing reactive oxygen species, as revealed in a number of studies. This study was performed to demonstrate the presence of oxidative ...

journal_title：Archives of dermatological research

authors： Yazici C,Köse K,Utaş S,Tanrikulu E,Taşlidere N

更新日期：2016-04-01 00:00:00

abstract：:To have as further insight into the localizations of immune deposits in the skin the reversed passive and the passive Arthus reactions were carried out in the foot-pads skin of guinea-pigs using horseradish peroxidase as antigen. The transient localizations of immune deposits in the papillary dermis and in the epiderm...

journal_title：Archives of dermatological research

authors： Ueki H,Nakaye M,Masuda T

更新日期：1980-01-01 00:00:00

abstract：:In the present study, attempts were made to clarify the role of an elastase-like enzyme in Arthus reaction by using rabbit-peritoneal polymorphonuclear leukocytes (PMNs). It was first confirmed that the injection of large amounts of PMNs with antibody can increase tissue damage in reversed Arthus reaction. The five va...

journal_title：Archives of dermatological research

authors： Hamanaka K,Toki N,Tsushima H,Takasugi S

更新日期：1984-01-01 00:00:00

abstract：:Patients with certain inflammatory skin diseases have multiple risk factors for venous thromboembolism (VTE). The objective of the study was to determine whether atopic dermatitis (AD), psoriasis, pemphigus, pemphigoid and/or hidradenitis is associated with VTE in US adults. Data were analyzed from the 2002-2012 Natio...

journal_title：Archives of dermatological research

authors： Shaheen MS,Silverberg JI

更新日期：2020-07-08 00:00:00

abstract：:Staphylococcus aureus is a common wound-infecting organism which can interact with cells via the extracellular matrix protein fibronectin (FN). The aim of this study was to determine the effect of the FN-binding protein (FnBP) of S. aureus on the behaviour of a human skin keratinocytes cell line (UP). FN-coated plates...

journal_title：Archives of dermatological research

authors： Kintarak S,Nair SP,Speight PM,Whawell SA

更新日期：2004-11-01 00:00:00

abstract：:Costimulation of anti-CD3-triggered proliferative T-cell responses by type I and type IV collagen and fibronectin was studied in 25 patients with psoriasis and 12 healthy subjects. The stimulation index of anti-CD3-mediated responses in the presence of type I collagen was about half that in the controls. Although the ...

journal_title：Archives of dermatological research

authors： Glinski W,Gorski A,Glinska-Ferenz M,Majewski S,Stepien-Sopniewska B

更新日期：1995-01-01 00:00:00

abstract：:We report the clinical features of 62 consecutive patients with lichen planus observed in 18 months. The largest number of cases occurred between 50 and 70 years of age. Thirty-four patients had lichen planus only. In the remainder, lichen planus was associated with chronic liver diseases (16 cases), immune-related di...

journal_title：Archives of dermatological research

authors： Cottoni F,Solinas A,Piga MR,Tocco A,Lissia M,Cerimele D

更新日期：1988-01-01 00:00:00

abstract：:The effects of oral 8-methoxypsoralen-photochemotherapy (PUVA-therapy) on the inflammatory infiltrate in 14 psoriatic skin lesions and on normal skin of 7 controls were investigated by means of autoradiography and planimetry. Under PUVA-therapy, one finds a significant decrease in dermal cells per millimeter lesion in...

journal_title：Archives of dermatological research

authors： Landthaler M,Plewig G,Hofmann C,Braun-Falco O

更新日期：1980-01-01 00:00:00

abstract：:This study concerns 57 patients who fulfilled histological criteria for the diagnosis allergic vasculitis. For 37 of these patients, biopsy specimen were available from lesional and adjacent non-lesional skin. Histological signs of vasculitis were found at both sites, but in clinically normal skin the perivascular inf...

journal_title：Archives of dermatological research

authors： Herrmann WA,Kauffmann RH,van Es LA,Daha MR,Meijer CJ

更新日期：1980-01-01 00:00:00

abstract：:A 61-year old woman developed a tumourous nodule in her left leg. Fifteen years ago a similar tumour had been removed in the same localization. Histological examination performed on biopsy material showed bundles of predominantly fusiform tumour cells with nuclear pleomorphism and many mitotic figures. Electron micros...

journal_title：Archives of dermatological research

authors： Seifert HW

更新日期：1978-11-10 00:00:00

abstract：:In this study, a new procedure for the cultivation of dermal vascular endothelial cells from guinea pig ear lobe was established, and specific binding of [3H]mepyramine to the cultured cell membranes was demonstrated. The vascular endothelial cells were successfully isolated from the dermis of guinea pig ear lobes by ...

journal_title：Archives of dermatological research

authors： Noso N,Hide M,Nakamura K,Yamamoto S

更新日期：1990-01-01 00:00:00

abstract：:Histamine is released from mast cells in the skin, causing urticaria and itching. However, little is known about the roles of histamine in development of eczematous lesions in contact dermatitis. Effects of histamine on development of eczematous lesions in contact dermatitis were assessed using histamine-deficient mic...

journal_title：Archives of dermatological research

authors： Seike M,Takata T,Ikeda M,Kodama H,Terui T,Ohtsu H

更新日期：2005-08-01 00:00:00

abstract：:The mechanistic target of rapamycin (mTOR) is involved in the regulation of cellular growth, proliferation, lipid synthesis, and protein translation. The mTOR pathway involves two complexes: the mechanistic target of rapamycin complex 1 (mTORC1) and the mechanistic target of rapamycin complex 2 (mTORC2). Both mTOR com...

journal_title：Archives of dermatological research

authors： Leo MS,Sivamani RK

更新日期：2014-12-01 00:00:00

abstract：:Although cell death by apoptosis has been recognized as an important control mechanism in the maintenance of tissue homeostasis and in the elimination of cells with damaged DNA, information on the induction and characteristics of apoptosis in keratinocytes is rather scarce. Apoptotic mechanisms may play an important r...

journal_title：Archives of dermatological research

authors： Henseleit U,Rosenbach T,Kolde G

更新日期：1996-10-01 00:00:00

abstract：:Dopamine causes reflex erythema, central blanching, and piloerection depending on the dose and the type of application wheal reaction. Intracutaneous application shows from 1.5 gamma/0.1 ml wheal formation, erythema, piloerection, and blanching combined with increased heat radiation from the skin surface (AGA thermovi...

journal_title：Archives of dermatological research

authors： Stüttgen G,Dreesen R

更新日期：1979-08-01 00:00:00

abstract：:Up to now, bicomponent keratohyalin has only been described for rat epithelium and human intraepidermal sweat ducts and fetal nail organ cells. In normal human interductal epidermis, the keratohyalin appears homogeneous, osmiophilic and stellate in shape. Under pathological conditions, bicomponent keratohyalin has bee...

journal_title：Archives of dermatological research

authors： Kastl I,Anton-Lamprecht I

更新日期：1990-01-01 00:00:00

abstract：:HaCaT keratinocytes differ from normal human epidermal keratinocytes (HEK) by constitutive expression of differentiation markers which are normally suppressed by vitamin A. In search of an explanation for this discrepancy we compared the vitamin A content, the expression of retinoid-binding proteins, and the vitamin A...

journal_title：Archives of dermatological research

authors： Törmä H,Rollman O,Vahlquist A

更新日期：1999-06-01 00:00:00

abstract：:Immigration of neutrophils into the epidermis is a hallmark of several so-called neutrophilic dermatoses. In this study we used a frozen section adhesion assay to study the impact of different activation procedures as well as of CD11 integrins on cell-cell adhesion between neutrophils and epidermal cells. Serial secti...

journal_title：Archives of dermatological research

authors： von den Driesch P,Weller M,Wörl P

更新日期：1997-11-01 00:00:00

abstract：:It is known that eosinophils are actively involved in allergy and inflammation. The granular components of eosinophils, eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin/eosinophil protein X (EDN/EPX), play an important role in such allergic and inflammatory processes. Prurigo nodularis is a chronic ...

journal_title：Archives of dermatological research

authors： Johansson O,Liang Y,Marcusson JA,Reimert CM

更新日期：2000-08-01 00:00:00

abstract：:Thymocyte selection-associated high-mobility group box (TOX) is aberrantly expressed in cutaneous T-cell lymphomas. In a recent study, TOX expression was noted unexpectedly in the follicle center (germinal center) B-cells of reactive lymph nodes and tonsils, used as external controls. To evaluate whether TOX is also e...

journal_title：Archives of dermatological research

authors： Schrader AM,Jansen PM,Willemze R

更新日期：2016-08-01 00:00:00

abstract：:Exposure to solar radiation is a major cause of environmental human skin damage. The main constituent of solar UV light is UVA radiation (320-400 nm); however, the need for protection against UVA has been marginalized for a long time. As a result, there is still a lack of useful agents for UVA protection. In this stud...

journal_title：Archives of dermatological research

authors： Rajnochová Svobodová A,Gabrielová E,Michaelides L,Kosina P,Ryšavá A,Ulrichová J,Zálešák B,Vostálová J

更新日期：2018-07-01 00:00:00

abstract：:Histochemical findings of primary and metastatic amelanotic melanomas were shown by the formaldehyde-induced fluorescence method (Falck and Hillarp). All or some of the amelanotic melanoma cells were discovered to emit green specific fluorescence. Results of the determination of 5-S-cysteinyldopa and DOPA in amelanoti...

journal_title：Archives of dermatological research

authors： Morishima T,Tatsumi F,Fukada E,Watanabe M,Nagashima N,Hanawa S

更新日期：1983-01-01 00:00:00

abstract：:Stratum corneum forms the UV barrier. The effect of ultraviolet B (UVB) on normal skin was extensively studied; however, its effect on barrier perturbed skin remains undefined. Both barrier perturbation and UVB irradiation induce endoplasmic reticulum (ER) stress and unfolded protein response (UPR) in keratinocytes. M...

journal_title：Archives of dermatological research

authors： Lee SE,Takagi Y,Nishizaka T,Baek JH,Kim HJ,Lee SH

更新日期：2017-09-01 00:00:00

abstract：:The aim of this study was to explore dermatologists' practices and attitudes related to educating and counseling their adolescent patients about indoor tanning. An online survey was carried out with a convenience sample of 100 dermatologists. Findings indicated that the majority of the dermatologists are actively enga...

journal_title：Archives of dermatological research

authors： Nahar VK,Wilkerson AH,Mayer JE,Gromley Z,Berry D,Nahar L,Brodell RT

更新日期：2020-11-01 00:00:00

abstract：:Scleroderma is a chronic fibrosing disease, in which an early inflammatory reaction precedes the fibrotic response. Systematic analysis of the pathways involved in the development of the disease together with information derived from novel animal models have helped to better understand the mechanisms that trigger and ...

journal_title：Archives of dermatological research

authors： Eckes B,Hunzelmann N,Moinzadeh P,Krieg T

更新日期：2007-06-01 00:00:00