LPS induces melanogenesis through p38 MAPK activation in human melanocytes.

abstract：:The effect of the proteolytic enzyme savinase on human plantar skin in vitro was examined by light and electron microscopy to elucidate the morphological involvement of activated savinase in human epidermis. Light microscopic examination of incubated skin fragments demonstrated that the histological changes produced b...

journal_title：Archives of dermatological research

authors： Imai S

更新日期：1991-01-01 00:00:00

abstract：:The present study aimed to observe the therapeutic effect of combined mizolastine and proteoglycan in chronic urticaria. The patients were randomly divided into the treatment group (n = 56) and the control group (n = 44). The treatment group was medicated with calcium gluconate (10 mg/ time, 1 time/day), vitamin D3 (i...

journal_title：Archives of dermatological research

authors： Xiong X,Song L,Chen F,Ma X

更新日期：2019-12-01 00:00:00

abstract：:Eleven dysplastic melanocytic naevi with various degrees of dysplasia, as judged by light microscopy, were studied by transmission electron microscopy, and their intra-epidermal melanocytes compared with those of five superficial spreading melanomas and seven common benign naevocellular naevi. Intra-epidermal melanocy...

journal_title：Archives of dermatological research

authors： Langer K,Rappersberger K,Steiner A,Konrad K,Wolff K

更新日期：1990-01-01 00:00:00

abstract：:The incidence of cutaneous malignant melanoma continues to rise. Strategies to reduce mortality in this situation include improving therapy, encouraging earlier diagnosis, and promoting prevention. New developments such as epiluminescence, sentinel node biopsy, arterial limb perfusion and the use of vaccines are discu...

journal_title：Archives of dermatological research

authors： MacKie RM

更新日期：1994-01-01 00:00:00

abstract：:The use of underarm cosmetics is common practice in the Western society to obtain better body odor and/or to prevent excessive sweating. A survey indicated that 95 % of the young adult Belgians generally use an underarm deodorant or antiperspirant. The effect of deodorants and antiperspirants on the axillary bacterial...

journal_title：Archives of dermatological research

authors： Callewaert C,Hutapea P,Van de Wiele T,Boon N

更新日期：2014-10-01 00:00:00

abstract：:In human skin, epidermal differentiation occurs in two ways: normal differentiation, characterized by keratin 10 expression, and alternative differentiation. Alternative differentiation can be hyperproliferation-associated differentiation (expression of keratin 16) or the reinduction of an embryonic type of differenti...

journal_title：Archives of dermatological research

authors： van Rossum MM,Mommers JM,van de Kerkhof PC,van Erp PE

更新日期：2000-01-01 00:00:00

abstract：:Using immunoblot and immunofluorescence analysis, we demonstrated the presence and localization of an immunoreactive form of erythrocyte ankyrin in human epidermal keratinocytes. Immunoblot analysis revealed that both human epidermis and cultured epidermal keratinocytes contained ankyrin-like proteins of molecular mas...

journal_title：Archives of dermatological research

authors： Shimizu T,Takakuwa Y,Koizumi H,Ishibashi T,Ohkawara A

更新日期：1996-01-01 00:00:00

abstract：:Using the sebum-absorbent tape technique, we have disclosed five different patterns of follicular sebum excretion rate (SER). These are the infantile, pubertal, acne, adult and aging patterns, distinguished by different densities of active sebaceous follicles, by distinct levels of follicular SER and by the relative s...

journal_title：Archives of dermatological research

authors： Piérard GE,Piérard-Franchimont C,Lê T,Lapière C

更新日期：1987-01-01 00:00:00

abstract：:Results of previous investigations have indicated that photochemotherapy (PUVA) attacks membranes of target cells. Using the combination of a stopped-flow technique and laser irradiation we were able to prove that the fast PUVA effect is explainable solely by the membrane damage. Lymphoid cells of healthy persons or p...

journal_title：Archives of dermatological research

authors： Böhm F,Meffert H,Bauer E

更新日期：1986-01-01 00:00:00

abstract：:The fetal development of Merkel cells-neuroendocrine cells of the skin - has been a matter of debate for a long time. Recent results have helped to confirm their intraepidermal development in humans. Simple epithelial cytokeratins (CK) nos. 8, 18, 19 and 20 are well established markers at the light microscopic level. ...

journal_title：Archives of dermatological research

authors： Moll I,Zieger W,Schmelz M

更新日期：1996-04-01 00:00:00

abstract：:Localized scleroderma (LoSc) is rare connective tissue disease that manifests with inflammation and fibrosis of the skin. Depending on the LoSc subtype, adjacent structures such as subcutaneous tissue, fascia, muscles, bones may be affected. The hallmark of fibrosis is tissue remodelling with excess deposition of extr...

journal_title：Archives of dermatological research

authors： Wolska-Gawron K,Bartosińska J,Krasowska D

更新日期：2020-07-01 00:00:00

abstract：:Forty-one male guinea pigs were treated orally with high doses of aromatic retinoid (Ro 10-9359) 25 mg/kg/day in oleum arachidis for 6 weeks. Twenty-three animals were investigated at the end of this treatment. The remaining 18 animals were investigated after an additional retinoid-free interval of 6 weeks. A control ...

journal_title：Archives of dermatological research

authors： Tsambaos D,Hundeiker M,Mahrle G,Orfanos CE

更新日期：1980-01-01 00:00:00

abstract：:To investigate the turnover of complete junctional membrane areas ("domain turnover"), psoriatic epidermis, keratoacanthoma, and squamous cell carcinoma were studied with an electron microscope and compared with the normal epidermis. Three types of domain turnover of junctions were observed. First, the uptake of intac...

journal_title：Archives of dermatological research

authors： Mahrle G

更新日期：1982-01-01 00:00:00

abstract：:CCN2 plays an important role in the pathogenesis of hypertrophic scars (HTSs). Although CCN2 is involved in many fibroproliferative events, the CCN2 induction signaling pathway in HTSs is yet to be elucidated. Here, we first investigated the effect of the mitogen-activated protein kinases (MAPKs) on CCN2-induced α-smo...

journal_title：Archives of dermatological research

authors： Hu X,Wang H,Liu J,Fang X,Tao K,Wang Y,Li N,Shi J,Wang Y,Ji P,Cai W,Bai X,Zhu X,Han J,Hu D

更新日期：2013-07-01 00:00:00

abstract：:Previous studies have demonstrated that permeability barrier disruption by acetone treatment significantly enhances skin permeability to both hydrophilic and amphipathic compounds, but not to highly lipophilic compounds. The purpose of the present study was to investigate the dependence of permeability on molecular we...

journal_title：Archives of dermatological research

authors： Tsai JC,Hung PL,Sheu HM

更新日期：2001-06-01 00:00:00

abstract：:Keloid is a complex condition with environmental and genetic risk-contributing factors. Two candidate genes, TGFβ1 and SMAD4, located in the same signaling pathway are highly expressed in the keloid fibroblast cells. In a case-control design, TGFβ1 haplotypes showed association with the risk of keloid in the present s...

journal_title：Archives of dermatological research

authors： Emami A,Halim AS,Salahshourifar I,Yussof SJ,Khoo TL,Kannan TP

更新日期：2012-09-01 00:00:00

abstract：:Programmed cell death protein-1 (PD-1) is primarily recognized as an inhibitory receptor involved in the regulation of immunological tolerance. However, recent studies have indicated that PD-1/PD-L1 signaling could also regulate the functions of nonimmune cells and may be involved in regulating hair biology. In this s...

journal_title：Archives of dermatological research

authors： Zhou L,Wen L,Sheng Y,Lu J,Hu R,Wang X,Lu Z,Yang Q

更新日期：2021-01-05 00:00:00

abstract：:Recently, we could show that the expression levels of the key regulators of the microRNA (miRNA) maturation and transport were dysregulated in inflamed hidradenitis suppurativa (HS) tissue (Heyam et al. in Wiley Interdiscip Rev RNA 6:271-289, 2015). The RNA-induced silencing complex (RISC) is the central element of th...

journal_title：Archives of dermatological research

authors： Hessam S,Sand M,Skrygan M,Bechara FG

更新日期：2017-09-01 00:00:00

abstract：:Intercellular adhesion molecule-1 (ICAM-1) is regularly expressed or inducible on all major cutaneous cell populations including Langerhans cells, keratinocytes, endothelial cells and dermal fibroblasts. ICAM-1 is induced in the skin under inflammatory conditions and plays an important role in the activation of T cell...

journal_title：Archives of dermatological research

authors： Chatelain R,Wollenberg A,Martin C,Panhans-Gross A,Bieber T,Degitz K,Heckmann M

更新日期：1998-09-01 00:00:00

abstract：:Congenital atrichia (AUC) is a form of isolated alopecia with an autosomal recessive mode of inheritance. Patients are born with normal hair but this is shed almost completely during the first weeks or months of life and never regrows. In many families the development of papular lesions is noted as an additional pheno...

journal_title：Archives of dermatological research

authors： Betz RC,Indelman M,Pforr J,Schreiner F,Bauer R,Bergman R,Lentze MJ,Nöthen MM,Cichon S,Sprecher E

更新日期：2007-06-01 00:00:00

abstract：:In 8 patients with idiopathic chronic urticaria suction blisters were produced simultaneously on lesional and perilesional skin in the periumbilical area without application of heat. The suction pressure was 250 mm Hg, and thus the blister production lasted from 60--120 min. The blister fluid histamine was determined ...

journal_title：Archives of dermatological research

authors： Bork K,König W,Böhm G

更新日期：1979-11-01 00:00:00

abstract：:Using a sensitive and modified solid-phase radioimmunoassay for detecting anti-cardiolipin antibodies, sera of 45 patients with lepromatous leprosy were examined. Nine of the 45 (20%) showed positive levels of anti-cardiolipin antibodies. Inhibition tests revealed that these antibodies significantly cross-reacted with...

journal_title：Archives of dermatological research

authors： Furukawa F,Kashihara M,Imamura S,Ohshio G,Hamashima Y

更新日期：1986-01-01 00:00:00

abstract：:Melanoma incidence in Australia remains the highest in the world; hence understanding its causation is paramount for future therapeutic developments. Multiple primary melanomas are also common occurrences among the Australian population with identified risk factors such as personal and family history of melanoma, fair...

journal_title：Archives of dermatological research

authors： Sinnya S,Jagirdar K,De'Ambrosis B,McMeniman E,Sturm RA,Soyer HP

更新日期：2015-10-01 00:00:00

abstract：:The effect of skin delipidization in humans on the percutaneous penetration of hydrocortisone was investigated in a cross-over trial. The delipidizing agent was 1:1:1 trichloroethane, a common industrial organic solvent. The findings do not show any significant difference in the topical absorption of hydrocortisone wi...

journal_title：Archives of dermatological research

authors： Bucks DA,Maibach HI,Menczel E,Wester RC

更新日期：1983-01-01 00:00:00

abstract：:The dependence of epithelial spread on human serum in culture has been studied. Using measured pieces of mouse ear skin epithelial outgrowth about floating explants (epiboly) and from adherent explants was studied. Where compared directly the two systems show similar results. Because of its ease of quantitation, the a...

journal_title：Archives of dermatological research

authors： Stenn KS,Dvoretzky I

更新日期：1979-02-23 00:00:00

abstract：:Paraneoplastic pemphigus patients (PNP) develop a group of autoantibodies, among which those against envoplakin and periplakin are almost always found. Epitope mapping has indicated that the linker subdomains of the proteins harbor the major antigenic sites recognized by PNP sera. In order to detect specific autoantib...

journal_title：Archives of dermatological research

authors： Huang Y,Li J,Zhu X

更新日期：2009-10-01 00:00:00

abstract：:Tropospheric ozone (O3) is a source of oxidative stress. This study examined the ability of a topical antioxidant (WEL-DS) to inhibit O3-mediated damage in a human epidermal skin model. Four groups of tissues (N = 24) were compared: Group 1 (control) were untreated and unexposed; Group 2 were untreated and exposed to ...

journal_title：Archives of dermatological research

authors： Pecorelli A,McDaniel DH,Wortzman M,Nelson DB

更新日期：2020-05-08 00:00:00

abstract：:Numerous reports have shown that psoriasis is associated with obesity and leptin. However, few reports are available on the association between serum leptin levels and leptin gene expression in SAT of psoriasis patients. To clarify this point, we examined serum leptin levels and expression levels of leptin messenger R...

journal_title：Archives of dermatological research

authors： Mitsuyama S,Abe F,Kimura M,Yoshida M,Higuchi T

更新日期：2015-08-01 00:00:00

abstract：:Atopic dermatitis (AD) is a frequent and burdensome disease. The objectives of this study were (1) to assess the willingness to pay (WTP) and quality of life (Qol) in AD patients and (2) to compare the results with data on other chronic skin diseases. To collect data, a non-interventional, cross-sectional nationwide p...

journal_title：Archives of dermatological research

authors： Beikert FC,Langenbruch AK,Radtke MA,Kornek T,Purwins S,Augustin M

更新日期：2014-04-01 00:00:00

abstract：:Patients with certain inflammatory skin diseases have multiple risk factors for venous thromboembolism (VTE). The objective of the study was to determine whether atopic dermatitis (AD), psoriasis, pemphigus, pemphigoid and/or hidradenitis is associated with VTE in US adults. Data were analyzed from the 2002-2012 Natio...

journal_title：Archives of dermatological research

authors： Shaheen MS,Silverberg JI

更新日期：2020-07-08 00:00:00