Abstract:
:Using the sebum-absorbent tape technique, we have disclosed five different patterns of follicular sebum excretion rate (SER). These are the infantile, pubertal, acne, adult and aging patterns, distinguished by different densities of active sebaceous follicles, by distinct levels of follicular SER and by the relative stability in time of the overall SER.
journal_name
Arch Dermatol Resjournal_title
Archives of dermatological researchauthors
Piérard GE,Piérard-Franchimont C,Lê T,Lapière Cdoi
10.1007/BF00585931subject
Has Abstractpub_date
1987-01-01 00:00:00pages
S104-7eissn
0340-3696issn
1432-069Xjournal_volume
279 Supplpub_type
杂志文章abstract::Topical vitamin D3 has relatively recently been introduced for the treatment of psoriasis. Synthetic vitamin D3 analogues with a high potential for inducing differentiation of cells, but with a low hypercalcemic effect have recently been developed. One such synthetic analogue of 1,25-dihydroxyvitamin D3 (calcitriol), ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050444
更新日期:1999-09-01 00:00:00
abstract::The immigration of circulating T cells into specific tissues is directed by the interaction between adhesion molecules on lymphocyte subpopulations and their ligands on vascular endothelium. Of these, endothelial leucocyte adhesion molecule (ELAM-1), weakly expressed in normal human skin (NHS), seems to be the counter...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00372006
更新日期:1993-01-01 00:00:00
abstract::Recent studies on eosinophilic fasciitis have lead to this investigation of eosinophilia in progressive systemic sclerosis and localized scleroderma. Eosinophilia (eosinophilic count greater than 300/cmm) was found in ten of 63 progressive systemic sclerosis patients (15.8%) and in two of nine localized scleroderma ca...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00406686
更新日期:1981-01-01 00:00:00
abstract::Psoriasis, a chronic inflammatory skin disease, is associated with oxidative stress of serum lipoproteins. In psoriatic children we evaluated the activity and levels of myeloperoxidase, the activity of paraoxonase-1 (PON1) and biochemical markers of lipid peroxidation, to investigate wether an unbalance between oxidan...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-019-01976-z
更新日期:2020-01-01 00:00:00
abstract::Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune blistering diseases characterized by a loss of cell-cell adhesion and by autoantibodies directed against epidermal cadherins. PF antigen has been established as desmoglein I which is located strictly on the desmosome, whereas the precise ultrastructur...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF02507101
更新日期:1996-06-01 00:00:00
abstract::Eighteen patients with atopic dermatitis were randomly chosen for a clinical trial to compare the action of the H2 receptor antagonist cimetidine in combination with the H1 receptor antagonist chorpheniramine against the chlorpheniramine alone and against placebo. Each treatment period lasted for 4 weeks. Intensity of...
journal_title:Archives of dermatological research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00412560
更新日期:1984-01-01 00:00:00
abstract::Close contacts between mast cells (MC) and nerve fibers have previously been demonstrated in normal and inflamed skin by light and electron microscopy. A key step for any study in MC-nerve interactions in situ is to simultaneously visualize both communication partners, preferably with the option of double labelling th...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050195
更新日期:1997-04-01 00:00:00
abstract::Mice homozygous for three different recessive mutations known to cause pleiotropic defects in the immune system and in the skin were used to evaluate the relationship between the classical immune system and dendritic epidermal cell populations. Numbers of Langerhans cells (LCs) and Thy-1+ dendritic cells (Thy-1+DEC) w...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00372621
更新日期:1990-01-01 00:00:00
abstract::The majority of studies on psoriasis have focused on explaining the genetic background and its associations with the immune system's response. The aim of this study was to identify the low-molecular weight compounds contributing to the metabolomic profile of psoriasis and to provide computational models that help with...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-017-1760-1
更新日期:2017-09-01 00:00:00
abstract::Stress is a well-known triggering factor along with genetic predisposition on the onset and during the course of psoriasis by altering the cellular constituents of the immune system. In the skin, there is a local hypothalamic-pituitary-adrenal (HPA) axis which is the equivalent of the central HPA axis. Corticotropin-r...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1218-4
更新日期:2012-03-01 00:00:00
abstract::Congenital atrichia (AUC) is a form of isolated alopecia with an autosomal recessive mode of inheritance. Patients are born with normal hair but this is shed almost completely during the first weeks or months of life and never regrows. In many families the development of papular lesions is noted as an additional pheno...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-007-0747-8
更新日期:2007-06-01 00:00:00
abstract::In the present study the action of various cytokines as regulators of human melanocyte growth and differentiation was examined in vitro. Primary melanocyte cultures were obtained in complete medium free of 12-O-tetradecanoylphorbol-13-acetate or serum. First passage melanocytes were treated with various concentrations...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF01105076
更新日期:1995-01-01 00:00:00
abstract::The topical application of a mixture of sugar and povidone--iodine (PI) has been reported to accelerate the healing of cutaneous wounds and ulcers by promoting re-epithelialization and granulation tissue formation as well as having an anti-microbial effect. To clarify the mechanisms accounting for the efficacy of a 70...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-006-0683-z
更新日期:2006-09-01 00:00:00
abstract::Mycosis fungoides was observed in a 71-year-old male with Mediterranean lymphoma, a B-cell malignancy. It is proposed that this association is not incidental since hypergammaglobulinaemia and even monoclonal gammopathies have repeatedly been described in cutaneous T-cell lymphomas. Mediterranean lymphoma might have re...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00417145
更新日期:1981-01-01 00:00:00
abstract::The aim of this study was to investigate the effects of Cervi cornus Colla (CCC) in the reconstruction of skin equivalent (SE). H&E staining showed that SE containing hyaluronic acid (HA) or HA and CCC had a thicker epidermis than the control SE. Immunohistochemical staining showed that p63 was mainly present at the b...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1283-8
更新日期:2013-01-01 00:00:00
abstract::In 8 patients with idiopathic chronic urticaria suction blisters were produced simultaneously on lesional and perilesional skin in the periumbilical area without application of heat. The suction pressure was 250 mm Hg, and thus the blister production lasted from 60--120 min. The blister fluid histamine was determined ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00418572
更新日期:1979-11-01 00:00:00
abstract::Photodynamic therapy (PDT) in dermatology has been proven to be a successful noninvasive therapeutic modality for treating skin cancer. To facilitate its clinical introduction, the development of topical photosensitizers is necessary to avoid generalized, cutaneous photosensitivity. Therefore the penetration of synthe...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050168
更新日期:1997-02-01 00:00:00
abstract::The expression of matrix metalloproteinase-2 was observed to be significantly upregulated in psoriasis. The aim of this study was to associate the DNA polymorphic variants in MMP-2 promoter gene with psoriasis and/or with psoriasis phenotypes related to psoriasis and comorbid heredity. In the total of 582 Czech Caucas...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-009-0947-5
更新日期:2009-07-01 00:00:00
abstract::In order to find, whether 8-MOP has an inhibiting effect on the proliferation of lymphocytes in the dark, we studied in vitro the lymphocyte proliferation by a mitogen (HgCl2) and by an antigen (tuberculin) from 16 psoriatic patients during the first oral PUVA treatment immediately before 8-MOP intake (03.--0.5 mg/kg ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00455295
更新日期:1978-05-31 00:00:00
abstract::Using immunoblot and immunofluorescence analysis, we demonstrated the presence and localization of an immunoreactive form of erythrocyte ankyrin in human epidermal keratinocytes. Immunoblot analysis revealed that both human epidermis and cultured epidermal keratinocytes contained ankyrin-like proteins of molecular mas...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF02505038
更新日期:1996-01-01 00:00:00
abstract::T Cells from 14 patients in the active stage of bullous pemphigoid and 10 patients in the inactive stage of the disease were studied with Leu-1, Leu-2, and Leu-3 monoclonal antibodies. The proportions of total T cells and T cells expressing either helper or suppressor phenotype in the peripheral blood of patients were...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00509086
更新日期:1985-01-01 00:00:00
abstract::All-trans retinoic acid (ATRA) is known to have beneficial effects on skin. It has been used extensively for the treatment of photodamaged skin. To assess the effects of all-trans retinoic acid on the dermis, specifically its effect on hyaluronate (hyaluronic acid, HA) synthesis and inhibition, tissue-engineered human...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-014-1460-z
更新日期:2014-09-01 00:00:00
abstract::Currently, there are no accurate and simple methods available to measure this risk of atrophy in patients treated with topical glucocorticosteroids. In the present clinical trial, we validated a new score (Dermaphot(®) score) to assess the atrophogenic potential of glucocorticosteroids. 36 healthy adult volunteers wer...
journal_title:Archives of dermatological research
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1007/s00403-012-1297-2
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Data on how patients with a history of skin cancer apply sunscreen are lacking. OBJECTIVE:To characterize (1) gender differences in sunscreen application technique (quantity used, anatomic site coverage, and time allocated) and (2) differences in sunscreen application to unaffected skin versus previous skin...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-020-02131-9
更新日期:2020-12-01 00:00:00
abstract::Human eccrine sweat glands were embedded in Lowicryl K4M. Cytokeratin proteins and blood group H antigen were localized by applying a postembedding immunogold method using a monoclonal antikeratin antibody and the lectin Ulex europaeus I. The antikeratin antibody labeled intermediate filaments in the secretory coil an...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00505639
更新日期:1990-01-01 00:00:00
abstract::Tranilast is used clinically as a drug for hypertrophic scars or keloids. Recently, the roles of keratinocytes in the pathogenesis of those conditions have been noted. Therefore, we first examined the effect of tranilast on the cell growth of normal human keratinocytes. A cell growth assay demonstrated that the cell n...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1291-8
更新日期:2012-11-01 00:00:00
abstract::Keloid is a fibrotic disease characterized by abnormal accumulation of extracellular matrix (ECM) in the dermis. It is a late spreading skin overgrowth and may be considered a plastic surgeon's nightmare. In nature, curcuminoid is composed of curcumin, demethoxycurcumin (DMC) and bisdemethoxycurcumin (bDMC). Curcumino...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-010-1075-y
更新日期:2010-12-01 00:00:00
abstract::Although chemokines are critical elements for the selective attraction and activation of various leukocyte subsets in the inflammatory process, there are few findings concerning T helper (Th) 1 or Th2 chemokines in autoimmune blistering disease (ABD). To determine whether serum levels of chemokines that are preferenti...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-006-0661-5
更新日期:2006-06-01 00:00:00
abstract::Cutaneous adverse drug reactions (ADRs) are common. However, no prospective study assessing cutaneous ADRs is available for Chinese populations. This study aimed to assess the incidence, manifestations, causative drugs, and other factors related to cutaneous ADRs. A total of 22,866 inpatients were surveyed prospective...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-015-1589-4
更新日期:2015-11-01 00:00:00
abstract::Marie Unna Hereditary Hypotrichosis 1 (MUHH1; OMIM 146550), a rare monogenic condition characterized by the development of sparse, twisted hair or complete hair loss, is the consequence of mutations located in the hairless (HR) gene. We have identified a 68-year-old Hungarian woman affected by alopecia universalis and...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1244-2
更新日期:2012-10-01 00:00:00