The association of PASI scores with CRH-R1 expression in patients with psoriasis.

abstract：:Results of previous investigations have indicated that photochemotherapy (PUVA) attacks membranes of target cells. Using the combination of a stopped-flow technique and laser irradiation we were able to prove that the fast PUVA effect is explainable solely by the membrane damage. Lymphoid cells of healthy persons or p...

journal_title：Archives of dermatological research

authors： Böhm F,Meffert H,Bauer E

更新日期：1986-01-01 00:00:00

abstract：:The established mouse epidermis-derived cell line HEL/30 was incubated in the presence of 3H arachidonic acid (AA) for 1 h. After medium removal, cells were reincubated with fresh medium in the presence or absence of the calcium ionophore A23187 and tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate (TPA). The AA me...

journal_title：Archives of dermatological research

authors： Tragni E,Caruso D,Porta S,Fumagalli R,Galli G,Galli CL

更新日期：1988-01-01 00:00:00

abstract：:CCN2 plays an important role in the pathogenesis of hypertrophic scars (HTSs). Although CCN2 is involved in many fibroproliferative events, the CCN2 induction signaling pathway in HTSs is yet to be elucidated. Here, we first investigated the effect of the mitogen-activated protein kinases (MAPKs) on CCN2-induced α-smo...

journal_title：Archives of dermatological research

authors： Hu X,Wang H,Liu J,Fang X,Tao K,Wang Y,Li N,Shi J,Wang Y,Ji P,Cai W,Bai X,Zhu X,Han J,Hu D

更新日期：2013-07-01 00:00:00

abstract：:The stimulation or inhibition of adenylate cyclase by hormones and chemicals is mediated by the stimulatory or inhibitory guanine nucleotide-binding proteins, Gs and Gi respectively. Although the presence of these G-proteins in the epidermis has been suggested, no direct information regarding their nature has been ava...

journal_title：Archives of dermatological research

authors： Takahashi H,Miyokawa N,Katagiri M,Iizuka H

更新日期：1990-01-01 00:00:00

abstract：:Botulinum toxin type A (BoNT-A) is an easy and fast treatment for gingival smile (GS). The objective of the study was to compare the reduction of gingival exposure using three different doses of abobotulinumtoxinA (ABO) in patients with different severities of anterior GS, and to assess treatment safety and patients' ...

journal_title：Archives of dermatological research

authors： Hexsel D,Dal'Forno T,Camozzato F,Valente I,Soirefmann M,Silva AF,Siega C

更新日期：2020-07-28 00:00:00

abstract：:Test results are reported of the effect of salicylic acid on the vasoconstrictive effect of flumethasone pivalate. In specific, the depigmentation of the skin (identical with increase in lightness of the skin) following topical application of flumethasone pivalate was investigated with the aid of an improved spectroph...

journal_title：Archives of dermatological research

authors： Wienert V,Blazek V

更新日期：1981-01-01 00:00:00

abstract：:Pathological alterations of capillaries, accelerated epidermopoesis, increased rate and extent of metabolism in the psoriatic lesion and first manifestation of psoriasis rarely in the first 20 years of life made us decide to investigate the human growth hormone (STH) in blood serum. In 70 patients suffering from psori...

journal_title：Archives of dermatological research

authors： Weber G,Neidhardt M,Schmidt A,Geiger A

更新日期：1981-01-01 00:00:00

abstract：:Propylene glycol (propane-1,2-diol) is the only diol widely used in dermatology. Pentane-1,5-diol is mainly used as a plasticizer in cellulose products and adhesives, in dental composites and in brake fluid compositions and as a preservative for grain. However, pentane-1,5-diol is also an effective solvent, water-bind...

journal_title：Archives of dermatological research

authors： Faergemann J,Wahlstrand B,Hedner T,Johnsson J,Neubert RH,Nyström L,Maibach H

更新日期：2005-12-01 00:00:00

abstract：:Solar radiation in the UVB range is absorbed primarily by the epidermal DNA where characteristic photodamage results in altered immune responses and mutagenic lesions. UVB exposure of the skin results in a profound upregulation of the anti-inflammatory cytokine, IL-10 and suppression of contact hypersensitivity (CHS)....

journal_title：Archives of dermatological research

authors： Ma LJ,Guzmán EA,DeGuzman A,Walter B,Muller HK,Walker AM,Owen LB

更新日期：2006-03-01 00:00:00

abstract：:Linoleic acid is required for the formation and maintenance of the epidermal barrier, but most of the current in vitro keratinocyte culture systems are linoleic acid-deficient. The aim of the present study was to examine the efficiency of linoleic acid uptake in human keratinocyte cultures grown under submerged and ai...

journal_title：Archives of dermatological research

authors： Vicanová J,Weerheim AM,Kempenaar JA,Ponec M

更新日期：1999-07-01 00:00:00

abstract：:The distribution of several markers of keratinocyte differentiation was studied in normal epidermis, basal cell carcinomas (BCCs), and squamous cell carcinomas (SCCs) using the immunoperoxidase technique on frozen sections of punch biopsy specimens. As markers a panel of chain-specific monoclonal antibodies (MoAbs) di...

journal_title：Archives of dermatological research

authors： Lavrijsen AP,Tieben LM,Ponec M,van der Schroeff JG,van Muijen GN

更新日期：1989-01-01 00:00:00

abstract：:Rosacea is a chronic skin disorder, characterized by persistent painful facial flushing and often accompanied by papules and pustules. To investigate the mechanism of facial flushing in rosacea, acetylcholine was administered by iontophoresis to a 10-mm diameter site in the forehead of 31 patients with rosacea and in ...

journal_title：Archives of dermatological research

authors： Drummond PD,Su D

更新日期：2012-03-01 00:00:00

abstract：:Metalloproteinase-mediated proteolysis plays an important role during all stages of wound repair. In acute murine wounds, murine collagenase, matrix metalloproteinase (MMP)-9, stromelysin-1, stromelysin-2 and tissue inhibitor of metalloproteinase (TIMP)-1 are strongly induced within 24 h after wounding. At the time of...

journal_title：Archives of dermatological research

authors： Madlener M

更新日期：1998-07-01 00:00:00

abstract：:Because of its easy accessibility, the skin is a very attractive target for gene therapy purposes. To study potential clinical applications in a preclinical setting, appropriate animal models are needed. Pig skin is very similar to human skin, and a variety of human diseases that are potentially amenable to gene thera...

journal_title：Archives of dermatological research

authors： Pfützner W,Joari MR,Foster RA,Vogel JC

更新日期：2006-06-01 00:00:00

abstract：:Localized scleroderma (LoSc) is rare connective tissue disease that manifests with inflammation and fibrosis of the skin. Depending on the LoSc subtype, adjacent structures such as subcutaneous tissue, fascia, muscles, bones may be affected. The hallmark of fibrosis is tissue remodelling with excess deposition of extr...

journal_title：Archives of dermatological research

authors： Wolska-Gawron K,Bartosińska J,Krasowska D

更新日期：2020-07-01 00:00:00

abstract：:Autoimmune diseases can be preceded by a symptom-free phase which is defined by the presence of autoantibodies, and may last for many years. These autoantibodies may have a high positive predictive value for disease onset, severity and organ-specific complications, especially in genetically prone individuals. Characte...

journal_title：Archives of dermatological research

authors： Nancy AL,Yehuda S

更新日期：2009-01-01 00:00:00

abstract：:In preparations of papillary dermis taken from clinically normal skin of patients with dermatitis herpetiformis (DH), the disappearance of granular IgA deposits induced by peptic digestion was partial at pH 4.5 and total at pH 4.1, as visualized by immunofluorescence microscopy. In a model system in which human monome...

journal_title：Archives of dermatological research

authors： Egelrud T,Bäck O

更新日期：1985-01-01 00:00:00

abstract：:Interleukin-33 is a novel and an unconventional member of IL-1 family. It is an inflammation-induced factor with dual function exercising its role as an intracellular regulator of gene expression, as well as, an extracellular alarm mediator. It is a ligand for ST2, a heterodimeric membrane-bound receptor of the orphan...

journal_title：Archives of dermatological research

authors： Balato A,Raimondo A,Balato N,Ayala F,Lembo S

更新日期：2016-07-01 00:00:00

abstract：:This study focused on the association between plaque psoriasis and polymorphisms of several inflammation genes. Included in the study were 142 Caucasian (Czech) patients with plaque psoriasis and 141 healthy subjects. The genotypes of the polymorphisms in angiotensinogen [M235T ATG, A(-6)G ATG], in transporters associ...

journal_title：Archives of dermatological research

authors： Vasků V,Vasků A,Izakovicová Hollá L,Tschöplová S,Kanková K,Benáková N,Semrádová V

更新日期：2000-11-01 00:00:00

abstract：:Female hairless mice (strain mutant hr/hr) have been irradiated with increasing doses of UV-B over a period of 4 weeks. They were compared with untreated controls Additional groups of 30 mice were treated with milk base or cream base or milk SPF6 or cream SPF6 or cream SPF8 daily before irradiation. No changes of body...

journal_title：Archives of dermatological research

authors： Vogel HG,Alpermann HG,Futterer E

更新日期：1981-01-01 00:00:00

abstract：:In order to improve the characterization of human malignant melanoma cells and their variant gene expression in vitro, a search for specifically regulated genes was performed. Four melanoma cell lines (M5, MEWO, IGR39, SKMEL13) and newly cultured normal human melanocytes were included in a comparative hybridization (d...

journal_title：Archives of dermatological research

authors： Eberle J,Garbe C,Orfanos CE

更新日期：1995-01-01 00:00:00

abstract：:Adult female Wistar rats (n = 48) divided into four groups of 12 were treated orally with 3 mg/kg per day thalidomide, a 0.05% hexachlorobenzene (HCB)--containing diet, with both drugs together and with the vehicles (controls) over periods of 10 and 60 days. The protein and P450 contents and the activities of aminopyr...

journal_title：Archives of dermatological research

authors： Tsambaos D,Bolsen K,Georgiou S,Monastirli A,Goerz G

更新日期：1994-01-01 00:00:00

abstract：:The effect of theophylline, an inhibitor of phosphodiesterase, on tyrosine (Tyr) transport across cell membrane was studied using cultured B-16 mouse melanoma cells. 1.5 mM Theophylline in culture medium increased Tyr uptake velocity in linear fashion up to 36 h, after which it reached a plateau at which the cells sho...

journal_title：Archives of dermatological research

authors： Saga K,Shimojo T

更新日期：1984-01-01 00:00:00

abstract：:Fast antigen is a cell surface protein that mediates apoptosis. Using immunohistological, flow cytometry and electron microscopic analyses, we investigated the expression of Fas antigen on various skin tissues, and on cultured SV40-transformed human epidermal keratinocyte cell line KJD and human skin squamous cell car...

journal_title：Archives of dermatological research

authors： Oishi M,Maeda K,Sugiyama S

更新日期：1994-01-01 00:00:00

abstract：:The aim of this study was to characterize the swelling behaviour of the stratum corneum. Stratum corneum pieces isolated from the breast region of 20 different females were incubated in distilled water at two different temperatures (20 degrees C and 45 degrees C) for 90 min and 24 h, respectively. Half of the stratum ...

journal_title：Archives of dermatological research

authors： Norlén L,Emilson A,Forslind B

更新日期：1997-08-01 00:00:00

abstract：:Recently a new thin layer chromatography plate (Whatman LK 6D) became available which is extremely easy to handle and permits highly reproducible qualitative and quantitative analysis. This plate proved to be of great value for the investigation of skin surface lipids. The use of a fatty acid methyl ester as an intern...

journal_title：Archives of dermatological research

authors： Weissmann A

更新日期：1979-07-30 00:00:00

abstract：:Glycerol, widely used as humectant, is known to protect against irritants and to accelerate recovery of irritated skin. However, most studies were done with topical formulations (i.e. emulsions) containing glycerol in relatively high amounts, preventing drawing conclusions from direct effects. In this study, acute che...

journal_title：Archives of dermatological research

authors： Atrux-Tallau N,Romagny C,Padois K,Denis A,Haftek M,Falson F,Pirot F,Maibach HI

更新日期：2010-08-01 00:00:00

abstract：:Interleukin-6 (IL-6) is a multifunctional cytokine which has been suggested to function as an autocrine mitogen in psoriatic epidermis. We report here the results of several experiments designed to further examine this hypothesis. Blot hybridization was unable to detect 1.3 kb IL-6 transcripts in RNA extracted from no...

journal_title：Archives of dermatological research

authors： Elder JT,Sartor CI,Boman DK,Benrazavi S,Fisher GJ,Pittelkow MR

更新日期：1992-01-01 00:00:00

abstract：:Based on reports suggesting aberrant cell-mediated immunity and altered infiltration of immunocompetent cells into the skin in psoriasis, we studied the stimulation of T cells by autologous non-T mononuclear leukocytes (autologous mixed lymphocyte reaction, AMLR) and by epidermal cells isolated from lesional and clini...

journal_title：Archives of dermatological research

authors： Schopf RE,Hoffmann A,Jung M,Morsches B,Bork K

更新日期：1986-01-01 00:00:00

abstract：:The use of underarm cosmetics is common practice in the Western society to obtain better body odor and/or to prevent excessive sweating. A survey indicated that 95 % of the young adult Belgians generally use an underarm deodorant or antiperspirant. The effect of deodorants and antiperspirants on the axillary bacterial...

journal_title：Archives of dermatological research

authors： Callewaert C,Hutapea P,Van de Wiele T,Boon N

更新日期：2014-10-01 00:00:00