Abstract:
:Test results are reported of the effect of salicylic acid on the vasoconstrictive effect of flumethasone pivalate. In specific, the depigmentation of the skin (identical with increase in lightness of the skin) following topical application of flumethasone pivalate was investigated with the aid of an improved spectrophotometric method. Using numeric lightness evaluation it was possible to demonstrate that salicylic acid increases the vasoconstriction.
journal_name
Arch Dermatol Resjournal_title
Archives of dermatological researchauthors
Wienert V,Blazek Vdoi
10.1007/BF00417384subject
Has Abstractpub_date
1981-01-01 00:00:00pages
19-27issue
1eissn
0340-3696issn
1432-069Xjournal_volume
271pub_type
杂志文章abstract::Typical confluent lesions of lichen planus were transplanted onto nude mice and cultured in organ culture. The characteristic histologic appearance of lichen planus disappeared after grafting and became similar to normal skin within 6 weeks on nude mice; the dense lymphocyte infiltrate in dermis disappeared, the basal...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00412684
更新日期:1988-01-01 00:00:00
abstract::Role of neurotrophic factors including nerve growth factor (NGF) in the mechanism of overgrowth and hypersensitivity of sensory nerve in atopic dermatitis (AD) has been proposed. Glial cell line-derived neurotrophic factor (GDNF) is a member of neurotrophic factors of the nervous systems; however, the role of GDNF in ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-008-0856-z
更新日期:2008-08-01 00:00:00
abstract::The penetration through the epidermis in vitro of various topically used corticosteroids was compared. The amount penetrating through the epidermis from an ethanolic solution showed good correlation with the polarity of the corticosteroids under study. Hydrocortisone, the most polar corticosteroid, penetrates the epid...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00412706
更新日期:1979-05-29 00:00:00
abstract::Nickel, cobalt and chromium are metals very often implicated in allergic contact dermatitis. In vivo, keratinocytes, which are the first target cells, can be directly activated to participate in the local reaction, especially through the expression of the membrane antigen ICAM-1, a ligand of the leucocyte antigen LFA-...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00371573
更新日期:1994-01-01 00:00:00
abstract::A low molecular mass cysteine proteinase inhibitor was found and isolated from bovine hoof. Purification of the inhibitor to homogeneity was performed by carboxymethyl-papain-sepharose affinity and DE-52 ion exchange chromatographies. From 15 g of bovine hoof, 0.25 mg of cysteine proteinase inhibitor was isolated. It ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF02505240
更新日期:1996-07-01 00:00:00
abstract::We have observed that lipopolysaccharide (LPS) induces pigmentation in melanocytes and in this study have examined whether these responses are mediated by the p38 mitogen-activated protein kinase (MAPK) signaling pathway. LPS appears to stimulate the pigmentation of melanocytes and cultured skin. LPS was found to indu...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-008-0863-0
更新日期:2008-07-01 00:00:00
abstract::The stimulation or inhibition of adenylate cyclase by hormones and chemicals is mediated by the stimulatory or inhibitory guanine nucleotide-binding proteins, Gs and Gi respectively. Although the presence of these G-proteins in the epidermis has been suggested, no direct information regarding their nature has been ava...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00372090
更新日期:1990-01-01 00:00:00
abstract::Human epidermal keratinocytes were grown in culture and the uptake of hematoporphyrin derivatives (HPDs) used in photodynamic therapy was estimated. Keratinocytes loaded with HPDs were irradiated with laser light of 632 nm generated by a helium-neon laser and cell toxicity was determined by the trypan blue exclusion t...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00510086
更新日期:1989-01-01 00:00:00
abstract::The cellular DNA ploidy of 30 cases of malignant melanoma was measured by 4',6-diamidino-2-phenylindole-DNA (DAPI-DNA) microfluorometry. DNA histograms and DNA index values were compared among melanomas of different cell morphology. Epithelioid cell melanomas often showed greater DNA aneuploidy than spindle cell melan...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00372134
更新日期:1993-01-01 00:00:00
abstract::Studies have identified increased prevalence of vitamin D deficiency in patients with alopecia areata (AA), an autoimmune disease characterized by hair loss, but none have prospectively examined vitamin D status and incident AA. In 55,929 women in the Nurses' Health Study (NHS), we prospectively evaluated the associat...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-016-1687-y
更新日期:2016-11-01 00:00:00
abstract::A suction blister device with a sensitive thermometer and with a temperature regulator was constructed. Utilizing this device, it was demonstrated that the cold challenge induces an increase in the skin temperature in cold urticaria patients during the cold challenge and a simultaneous release of histamine into the su...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00404624
更新日期:1984-01-01 00:00:00
abstract::The adenylate cyclase system of an established human trichilemmoma cell line was investigated. Stimulators of human epidermal adenylate cyclase system, epinephrine, histamine, adenosine, and prostaglandin E increased cyclic AMP levels of the trichilemmoma cells. The effects of epinephrine, histamine, and adenosine wer...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00413285
更新日期:1987-01-01 00:00:00
abstract::It has been suggested that free fatty acids (FFA) such as palmitate, which are secreted from enlarged adipocytes in the subcutaneous fat of obese subjects, serve as a link between obesity and altered skin functions. Cyclooxygenease-2 (COX-2) and prostanoids participate in the induction of impaired dermal function. In ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-013-1434-6
更新日期:2014-05-01 00:00:00
abstract::Comparative measurements of collagen synthesis as a portion of total protein synthesis were performed with fragments of peripheral neurofibromas, of skin adjacent to the tumors, and of unaffected skin from patients with neurofibromatosis (NF). No significant difference was found among these various samples. Collagen s...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00412930
更新日期:1986-01-01 00:00:00
abstract::Interleukin-6-like (IL-6-like) immunoreactivity was sought in inflamed and normal human skin using the same immunohistochemical technique as for detection of neuropeptides. Such immunoreactivity was found in dermal and in a few intraepidermal nerve-like fibres in biopsy specimens from inflamed skin from patients with ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF02505230
更新日期:1996-07-01 00:00:00
abstract::The mechanism of action of thalidomide in the treatment of patients with Behçet's disease (BD) is poorly understood. There is some evidence to suggest that certain immunological abnormalities are associated with the pathogenesis of BD. A BD-like mouse model induced by herpes simplex virus (HSV) inoculation shows simil...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-004-0498-8
更新日期:2004-09-01 00:00:00
abstract::Serotonin is a monoamine acting as a neuromediator in the central and peripheral nervous system. Recently, serotonin has also been shown to influence T- and B-cell function. The serotonin transporter is central in the regulation of the serotonergic system and widely expressed on cells of the immune system. A functiona...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-008-0909-3
更新日期:2009-07-01 00:00:00
abstract::The incidence of epithelioid sarcoma among patients with malignant soft tissue tumors is small, but the rates of recurrence and metastasis of this type of sarcoma are high. To date, effective chemotherapy for advanced epithelioid sarcoma has not been established and, furthermore, epithelioid sarcoma is known to exhibi...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030000127
更新日期:2000-06-01 00:00:00
abstract::Heparin-binding EGF-like growth factor (HB-EGF) and amphiregulin (AREG) are the members of EGF family that bind to common EGF receptor (EGFR) in the epidermis. However, the role of these two growth factors in epidermal hyperplasia of psoriasis has not been established. On the other hand, CD4+ T cells are responsible f...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-007-0809-y
更新日期:2008-01-01 00:00:00
abstract::Pathological alterations of capillaries, accelerated epidermopoesis, increased rate and extent of metabolism in the psoriatic lesion and first manifestation of psoriasis rarely in the first 20 years of life made us decide to investigate the human growth hormone (STH) in blood serum. In 70 patients suffering from psori...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00408223
更新日期:1981-01-01 00:00:00
abstract::Nephrogenic systemic fibrosis (NSF) is a disease characterized by fibrosis of the systemic organs in patients with renal failure. Following the findings of recent epidemiological studies and the finding of gadolinium (Gd) in the skin tissue of NSF patients, it is now definitely known that the use of Gd contrast agents...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-016-1689-9
更新日期:2016-12-01 00:00:00
abstract::In preparations of papillary dermis taken from clinically normal skin of patients with dermatitis herpetiformis (DH), the disappearance of granular IgA deposits induced by peptic digestion was partial at pH 4.5 and total at pH 4.1, as visualized by immunofluorescence microscopy. In a model system in which human monome...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00412495
更新日期:1985-01-01 00:00:00
abstract::HLA types were determined in 19 patients and 9 healthy members of 2 Danish families with hereditary angioneurotic edema. The study revealed no connections between hereditary angioneurotic edema and the HLA system. ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00409265
更新日期:1982-01-01 00:00:00
abstract::Primary cultures of guinea pig ear keratinocytes were treated with vitamin A acid at plating, or at 14 h or 14 days after plating. The intracellular content of the cyclic nucleotides cAMP and cGMP was determined by radioimmunoassay at intervals during a period of 50 h after treatment. When added at plating, vitamin A ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00416918
更新日期:1980-01-01 00:00:00
abstract::Androgenetic alopecia (AGA) is a dermatological disorder of scalp hair loss characterized by a progressive miniaturization of hair follicles with shortened anagen phase leading to a decreased number of hairs on the scalp. It is a complex polygenic trait prevailing around two-thirds of the male population. Elevated exp...
journal_title:Archives of dermatological research
pub_type: 杂志文章,评审
doi:10.1007/s00403-018-1826-8
更新日期:2018-07-01 00:00:00
abstract::Skin topography and microvasculature undergo characteristic changes with age. Although several non-invasive bioengineering methods are currently available to measure them quantitatively, few publications have referred to their relationship with age in different anatomical sites. This study was carried out to observe t...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-005-0628-y
更新日期:2006-03-01 00:00:00
abstract::Conditions of oxidative stress lead to down-regulation of glutathione (GSH) and glutathione peroxidase (GPO), which could be responsible for tyrosinase induction in pigment cells. To address this question, the effects of selective modulation of GSH metabolism on melanogenic parameters of slightly and highly melanized ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050202
更新日期:1997-05-01 00:00:00
abstract::Topical vitamin D3 has relatively recently been introduced for the treatment of psoriasis. Synthetic vitamin D3 analogues with a high potential for inducing differentiation of cells, but with a low hypercalcemic effect have recently been developed. One such synthetic analogue of 1,25-dihydroxyvitamin D3 (calcitriol), ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050444
更新日期:1999-09-01 00:00:00
abstract::Genetic abnormalities for different subtypes of epidermolysis bullosa (EB) have been described. In dominant simplex type EB, mutations of the K5 or K14 gene lead to disruption of basal cells and the formation of bullae. The recessive simplex types include EB with muscular dystrophy due to abnormal plectin, EB without ...
journal_title:Archives of dermatological research
pub_type: 杂志文章,评审
doi:10.1007/s00403-002-0369-0
更新日期:2003-04-01 00:00:00
abstract::Recently, we discovered that New Zealand rabbits immunized with human type V collagen plus Freund's adjuvant present fibrosis and vasculitis of organs usually affected by systemic sclerosis. In this way, we studied the fibrillogenesis process to identify possible factors involved in altered remodeling observed in this...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-006-0645-5
更新日期:2006-07-01 00:00:00