Abstract:
:HLA types were determined in 19 patients and 9 healthy members of 2 Danish families with hereditary angioneurotic edema. The study revealed no connections between hereditary angioneurotic edema and the HLA system.
journal_name
Arch Dermatol Resjournal_title
Archives of dermatological researchauthors
Eggert J,Zachariae H,Svejgaard E,Svejgaard A,Kissmeyer-Nielsen Fdoi
10.1007/BF00409265subject
Has Abstractpub_date
1982-01-01 00:00:00pages
347-8issue
3-4eissn
0340-3696issn
1432-069Xjournal_volume
273pub_type
杂志文章abstract::Exposure to solar radiation is a major cause of environmental human skin damage. The main constituent of solar UV light is UVA radiation (320-400 nm); however, the need for protection against UVA has been marginalized for a long time. As a result, there is still a lack of useful agents for UVA protection. In this stud...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-018-1828-6
更新日期:2018-07-01 00:00:00
abstract::Intercellular adhesion molecule-1 (ICAM-1) is regularly expressed or inducible on all major cutaneous cell populations including Langerhans cells, keratinocytes, endothelial cells and dermal fibroblasts. ICAM-1 is induced in the skin under inflammatory conditions and plays an important role in the activation of T cell...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050339
更新日期:1998-09-01 00:00:00
abstract::Three new cromones have been studied that are supposed to be better absorbed and to have a wider spectrum of anti-allergic activity than disodium cromoglycate. Pretreatment with i.d. injection of 10 microgram FPL 52758 significantly reduced the weal and flare reaction induced by specific antigen in 11 patients with at...
journal_title:Archives of dermatological research
pub_type: 临床试验,杂志文章
doi:10.1007/BF00403843
更新日期:1980-01-01 00:00:00
abstract::Keloid is a complex condition with environmental and genetic risk-contributing factors. Two candidate genes, TGFβ1 and SMAD4, located in the same signaling pathway are highly expressed in the keloid fibroblast cells. In a case-control design, TGFβ1 haplotypes showed association with the risk of keloid in the present s...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1262-0
更新日期:2012-09-01 00:00:00
abstract::Lichen planus (LP) is a chronic inflammatory, T cell-mediated autoimmune skin disease. Innate immunity could explain the interplay between environmental triggers and the autoimmune cascade leading to disease development. Toll-like receptors (TLRs) are important components of the innate immune system, with no previous ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1267-8
更新日期:2013-03-01 00:00:00
abstract::Cutaneous adverse drug reactions (ADRs) are common. However, no prospective study assessing cutaneous ADRs is available for Chinese populations. This study aimed to assess the incidence, manifestations, causative drugs, and other factors related to cutaneous ADRs. A total of 22,866 inpatients were surveyed prospective...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-015-1589-4
更新日期:2015-11-01 00:00:00
abstract::The effects of oral 8-methoxypsoralen-photochemotherapy (PUVA-therapy) on the inflammatory infiltrate in 14 psoriatic skin lesions and on normal skin of 7 controls were investigated by means of autoradiography and planimetry. Under PUVA-therapy, one finds a significant decrease in dermal cells per millimeter lesion in...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00404455
更新日期:1980-01-01 00:00:00
abstract::The effect of skin delipidization in humans on the percutaneous penetration of hydrocortisone was investigated in a cross-over trial. The delipidizing agent was 1:1:1 trichloroethane, a common industrial organic solvent. The findings do not show any significant difference in the topical absorption of hydrocortisone wi...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00416669
更新日期:1983-01-01 00:00:00
abstract::Although cell death by apoptosis has been recognized as an important control mechanism in the maintenance of tissue homeostasis and in the elimination of cells with damaged DNA, information on the induction and characteristics of apoptosis in keratinocytes is rather scarce. Apoptotic mechanisms may play an important r...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF02505277
更新日期:1996-10-01 00:00:00
abstract::This study was designed to investigate the effects of griseofulvin, 5-fluorocytosine (5-FC), and amphotericin B on pancreatic and gastric secretion after the administration of a single large dose, or repeated small doses for 3 weeks, in male albino rats. The exocrine functions of the main digestive glands were only sl...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00694617
更新日期:1979-10-01 00:00:00
abstract::Results of previous investigations have indicated that photochemotherapy (PUVA) attacks membranes of target cells. Using the combination of a stopped-flow technique and laser irradiation we were able to prove that the fast PUVA effect is explainable solely by the membrane damage. Lymphoid cells of healthy persons or p...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00404352
更新日期:1986-01-01 00:00:00
abstract::Keratin specificity analyses of eight anti-keratin antibodies (34 beta B4 (K1), 35 beta H11 (K8), Ks 13.1 (K13), Ks 19.1 (K19), PKK1, LP34 (CK1), KL1 and AE1) using keratin protein derived from normal thigh epidermis, normal parotid gland and a human squamous cell carcinoma cell line (HSC-5) were performed, and compar...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00370816
更新日期:1993-01-01 00:00:00
abstract::Previous studies showed an association between various dermatological diseases and epicardial fat thickness (EFT). However, EFT, which has been accepted as a cardiometabolic risk factor in recent years, has not been studied in the context of hidradenitis suppurativa (HS). Therefore, we aimed to determine whether EFT i...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-019-02032-6
更新日期:2020-09-01 00:00:00
abstract::Currently, there are no accurate and simple methods available to measure this risk of atrophy in patients treated with topical glucocorticosteroids. In the present clinical trial, we validated a new score (Dermaphot(®) score) to assess the atrophogenic potential of glucocorticosteroids. 36 healthy adult volunteers wer...
journal_title:Archives of dermatological research
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1007/s00403-012-1297-2
更新日期:2013-04-01 00:00:00
abstract::Marie Unna Hereditary Hypotrichosis 1 (MUHH1; OMIM 146550), a rare monogenic condition characterized by the development of sparse, twisted hair or complete hair loss, is the consequence of mutations located in the hairless (HR) gene. We have identified a 68-year-old Hungarian woman affected by alopecia universalis and...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1244-2
更新日期:2012-10-01 00:00:00
abstract::Histochemical findings of primary and metastatic amelanotic melanomas were shown by the formaldehyde-induced fluorescence method (Falck and Hillarp). All or some of the amelanotic melanoma cells were discovered to emit green specific fluorescence. Results of the determination of 5-S-cysteinyldopa and DOPA in amelanoti...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00417207
更新日期:1983-01-01 00:00:00
abstract::Enhanced susceptibility to viral infections has been reported repeatedly in atopic dermatitis (AD). A difference in the capacity to produce interferons (IFN) in response to viral antigens may be the cause. In the present study we investigated the in vitro IFN production of leukocytes from AD patients in response to di...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00585921
更新日期:1987-01-01 00:00:00
abstract::Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune blistering diseases characterized by a loss of cell-cell adhesion and by autoantibodies directed against epidermal cadherins. PF antigen has been established as desmoglein I which is located strictly on the desmosome, whereas the precise ultrastructur...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF02507101
更新日期:1996-06-01 00:00:00
abstract::The aim of this study was to investigate the effects of Cervi cornus Colla (CCC) in the reconstruction of skin equivalent (SE). H&E staining showed that SE containing hyaluronic acid (HA) or HA and CCC had a thicker epidermis than the control SE. Immunohistochemical staining showed that p63 was mainly present at the b...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1283-8
更新日期:2013-01-01 00:00:00
abstract::Exposure to ultraviolet (UV) irradiation has detrimental effects on skin accompanied by the increased metabolism of hyaluronan (HA), a linear polysaccharide important for the normal physiological functions of skin. In this study, the modulation of human keratinocyte response to UVB irradiation by HA (970 kDa) was inve...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-011-1146-8
更新日期:2011-05-01 00:00:00
abstract::Human epidermal keratinocytes were grown in culture and the uptake of hematoporphyrin derivatives (HPDs) used in photodynamic therapy was estimated. Keratinocytes loaded with HPDs were irradiated with laser light of 632 nm generated by a helium-neon laser and cell toxicity was determined by the trypan blue exclusion t...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00510086
更新日期:1989-01-01 00:00:00
abstract::A low molecular mass cysteine proteinase inhibitor was found and isolated from bovine hoof. Purification of the inhibitor to homogeneity was performed by carboxymethyl-papain-sepharose affinity and DE-52 ion exchange chromatographies. From 15 g of bovine hoof, 0.25 mg of cysteine proteinase inhibitor was isolated. It ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF02505240
更新日期:1996-07-01 00:00:00
abstract::Previous studies have demonstrated that permeability barrier disruption by acetone treatment significantly enhances skin permeability to both hydrophilic and amphipathic compounds, but not to highly lipophilic compounds. The purpose of the present study was to investigate the dependence of permeability on molecular we...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030100229
更新日期:2001-06-01 00:00:00
abstract::Solar ultraviolet (UV) irradiation causes damages on human skin and premature skin aging (photoaging). UV-induced reduction of type I collagen in dermis is widely considered primarily induction of wrinkled appearance of photoaging skin. Type I procollagen synthesis is reduced under UV irradiation by blocking transform...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-007-0805-2
更新日期:2008-04-01 00:00:00
abstract::Bradykinin has long been postulated to have a major role in physiologic human pain production. We have developed a method to systematically quantify the algogenic response to bradykinin in human skin by the direct application of bradykinin to suction blister bases. After determination of the pain threshold to bradykin...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00371917
更新日期:1992-01-01 00:00:00
abstract::Scleroderma is a chronic fibrosing disease, in which an early inflammatory reaction precedes the fibrotic response. Systematic analysis of the pathways involved in the development of the disease together with information derived from novel animal models have helped to better understand the mechanisms that trigger and ...
journal_title:Archives of dermatological research
pub_type: 杂志文章,评审
doi:10.1007/s00403-007-0756-7
更新日期:2007-06-01 00:00:00
abstract::Electron microscopic aspects in ten cases of normolipidemic cutaneous xanthomatosis have been investigated. Two additional types IV and V hyperlipoproteinaemic xanthomatosis have also been included. Ultrastructural findings in all cases were similar. Abundant histiocytic cells with numerous intracytoplasmic lipid vacu...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00694624
更新日期:1979-10-01 00:00:00
abstract::Despite the fact that polymorphous light eruption (PLE) is the most common photodermatosis, affecting 15% of healthy people in the UK, its pathogeny remains unclear. The condition is more frequent in females and begins often in young adults and in mid-adult life. The mechanism of PLE is under active research as shown ...
journal_title:Archives of dermatological research
pub_type: 信件
doi:10.1007/s00403-004-0508-x
更新日期:2004-10-01 00:00:00
abstract::Immigration of neutrophils into the epidermis is a hallmark of several so-called neutrophilic dermatoses. In this study we used a frozen section adhesion assay to study the impact of different activation procedures as well as of CD11 integrins on cell-cell adhesion between neutrophils and epidermal cells. Serial secti...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050263
更新日期:1997-11-01 00:00:00
abstract::Myotonic muscular dystrophy (MMD) is caused by an abnormal function of RNA-binding proteins (RBP) resulting in DNA spliceopathy. A case of a patient, with MMD multiple basal and squamous cell carcinomas and dysplastic nevi, is described. The association between MMD and non-melanoma skin cancer has been reported before...
journal_title:Archives of dermatological research
pub_type: 新闻
doi:10.1007/s00403-009-0997-8
更新日期:2010-04-01 00:00:00