Association between basal, squamous cell carcinomas, dysplastic nevi and myotonic muscular dystrophy indicates an important role of RNA-binding proteins in development of human skin cancer.

abstract：:To investigate biological characteristics of syringomas, three-dimensional (3-D) architectures of epithelial tumor nests and luminal structures of syringomas, hair follicles, and epidermal basement membrane in skin lesions were reconstructed using a computer stereographic analysis. Each lesion was composed of many sph...

journal_title：Archives of dermatological research

authors： Ito M,Yokoyama H,Ikeda K,Sato Y

更新日期：1990-01-01 00:00:00

abstract：:In the case of viral acanthomas, the stratum spinosum and granulosum presents ballooned cells which contain all transitional stages from multivesicular bodies (MVB) to keratinosomes. A particularity in condylomata acuminata are the "wagon-wheel" bodies. These structures are typical for the non keratinazed squamous epi...

journal_title：Archives of dermatological research

authors： Heine H,Schaeg G,Nasemann T

更新日期：1978-01-01 00:00:00

abstract：:An animal experiment is presented in which two groups of pigmented hairless mice were exposed daily to suberythemal doses of UVA to study tumourigenesis. The aim of the study was to estimate the carcinogenic risks of tanning by UVA. The pigmented hairless mice, Skh-hr2, were separated by selective breeding into two gr...

journal_title：Archives of dermatological research

authors： van Weelden H,van der Putte SC,Toonstra J,van der Leun JC

更新日期：1990-01-01 00:00:00

abstract：:This study concerns 57 patients who fulfilled histological criteria for the diagnosis allergic vasculitis. For 37 of these patients, biopsy specimen were available from lesional and adjacent non-lesional skin. Histological signs of vasculitis were found at both sites, but in clinically normal skin the perivascular inf...

journal_title：Archives of dermatological research

authors： Herrmann WA,Kauffmann RH,van Es LA,Daha MR,Meijer CJ

更新日期：1980-01-01 00:00:00

abstract：:T Cells from 14 patients in the active stage of bullous pemphigoid and 10 patients in the inactive stage of the disease were studied with Leu-1, Leu-2, and Leu-3 monoclonal antibodies. The proportions of total T cells and T cells expressing either helper or suppressor phenotype in the peripheral blood of patients were...

journal_title：Archives of dermatological research

authors： Ahmed AR

更新日期：1985-01-01 00:00:00

abstract：:Little attention has been given to the involvement of sweat glands/ducts in the pathogenesis of prurigo nodularis (PN). According to recent studies, PN is likely to develop under conditions characterized by dry skin, such as atopic dermatitis (AD), suggesting a strong impact of skin dryness on PN development. No thera...

journal_title：Archives of dermatological research

authors： Katayama C,Hayashida Y,Sugiyama S,Shiohara T,Aoyama Y

更新日期：2019-09-01 00:00:00

abstract：:We have observed that lipopolysaccharide (LPS) induces pigmentation in melanocytes and in this study have examined whether these responses are mediated by the p38 mitogen-activated protein kinase (MAPK) signaling pathway. LPS appears to stimulate the pigmentation of melanocytes and cultured skin. LPS was found to indu...

journal_title：Archives of dermatological research

authors： Ahn JH,Jin SH,Kang HY

更新日期：2008-07-01 00:00:00

abstract：:Mite antigens play important roles in the pathogenesis of atopic dermatitis (AD). We recently developed a novel air cleaner (KC-850U) using charged plasma cluster ions to eliminate a variety of allergens from house environments. The present work demonstrates the ability of KC-850U to decrease the symptoms of AD induce...

journal_title：Archives of dermatological research

authors： Hiramoto K,Orita K,Yamate Y,Sato EF,Okano H,Nishikawa K,Inoue M

更新日期：2011-07-01 00:00:00

abstract：:Koebner response was studied in 35 psoriatic patients. Two punch biopsies per patient were taken from non-lesional psoriatic skin before, and 6 h, 2 days, 7 days, 14 days and 21 days after, tape stripping. Alterations in the numbers of CD1+ Langerhans cells, CD4+ and CD8+ T cells and CD11c+ macrophages were mapped mor...

journal_title：Archives of dermatological research

authors： Paukkonen K,Naukkarinen A,Horsmanheimo M

更新日期：1992-01-01 00:00:00

abstract：:The aim of this study was to investigate the effects of Cervi cornus Colla (CCC) in the reconstruction of skin equivalent (SE). H&E staining showed that SE containing hyaluronic acid (HA) or HA and CCC had a thicker epidermis than the control SE. Immunohistochemical staining showed that p63 was mainly present at the b...

journal_title：Archives of dermatological research

authors： Kim J,Jeong HS,Li H,Baek KJ,Kwon NS,Yun HY,Choi HR,Park KC,Kim DS

更新日期：2013-01-01 00:00:00

abstract：:The distribution of several markers of keratinocyte differentiation was studied in normal epidermis, basal cell carcinomas (BCCs), and squamous cell carcinomas (SCCs) using the immunoperoxidase technique on frozen sections of punch biopsy specimens. As markers a panel of chain-specific monoclonal antibodies (MoAbs) di...

journal_title：Archives of dermatological research

authors： Lavrijsen AP,Tieben LM,Ponec M,van der Schroeff JG,van Muijen GN

更新日期：1989-01-01 00:00:00

abstract：:Interleukin-33 is a novel and an unconventional member of IL-1 family. It is an inflammation-induced factor with dual function exercising its role as an intracellular regulator of gene expression, as well as, an extracellular alarm mediator. It is a ligand for ST2, a heterodimeric membrane-bound receptor of the orphan...

journal_title：Archives of dermatological research

authors： Balato A,Raimondo A,Balato N,Ayala F,Lembo S

更新日期：2016-07-01 00:00:00

abstract：:We report the clinical features of 62 consecutive patients with lichen planus observed in 18 months. The largest number of cases occurred between 50 and 70 years of age. Thirty-four patients had lichen planus only. In the remainder, lichen planus was associated with chronic liver diseases (16 cases), immune-related di...

journal_title：Archives of dermatological research

authors： Cottoni F,Solinas A,Piga MR,Tocco A,Lissia M,Cerimele D

更新日期：1988-01-01 00:00:00

abstract：:Paraneoplastic pemphigus patients (PNP) develop a group of autoantibodies, among which those against envoplakin and periplakin are almost always found. Epitope mapping has indicated that the linker subdomains of the proteins harbor the major antigenic sites recognized by PNP sera. In order to detect specific autoantib...

journal_title：Archives of dermatological research

authors： Huang Y,Li J,Zhu X

更新日期：2009-10-01 00:00:00

abstract：:Mycosis fungoides was observed in a 71-year-old male with Mediterranean lymphoma, a B-cell malignancy. It is proposed that this association is not incidental since hypergammaglobulinaemia and even monoclonal gammopathies have repeatedly been described in cutaneous T-cell lymphomas. Mediterranean lymphoma might have re...

journal_title：Archives of dermatological research

authors： Cassuto JP,Kövary PM,Campagni JP,Simony J,Maiolini R,Schneider M

更新日期：1981-01-01 00:00:00

abstract：:Bromodeoxyuridine (BrdU) has commonly been used for detecting of label-retaining cells (LRCs). To determine if there are LRCs and the distributions of LRCs in eccrine sweat glands, 20 newborn SD rats within 24 h after birth were injected intraperitoneally with 50 mg/kg/time BrdU four consecutive times at 2-h intervals...

journal_title：Archives of dermatological research

authors： Chen L,Zhang M,Li H,Tang S,Fu X

更新日期：2014-03-01 00:00:00

abstract：:IL-6/STAT3 signaling pathway has been suggested to play a role in CTCL pathogenesis. Polymorphisms in STAT3 signaling pathway-related genes might be a risk factor for CTCL. However, the exact role of inherited gene polymorphisms of IL-6 and STAT3 in the pathogenesis of CTCL is still not fully understood. The aim was t...

journal_title：Archives of dermatological research

authors： Olszewska B,Gleń J,Zabłotna M,Nowicki RJ,Sokołowska-Wojdyło M

更新日期：2021-01-01 00:00:00

abstract：:The established mouse epidermis-derived cell line HEL/30 was incubated in the presence of 3H arachidonic acid (AA) for 1 h. After medium removal, cells were reincubated with fresh medium in the presence or absence of the calcium ionophore A23187 and tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate (TPA). The AA me...

journal_title：Archives of dermatological research

authors： Tragni E,Caruso D,Porta S,Fumagalli R,Galli G,Galli CL

更新日期：1988-01-01 00:00:00

abstract：:Primary hyperhidrosis is a condition characterized by excessive sweating. The estimated prevalence is between 0.6 and 4.4%, and it can have economic, psychological, and social consequences for affected individuals. Family and genetic studies have suggested a genetic component in the inheritance of the disease. In this...

journal_title：Archives of dermatological research

authors： Henning MA,Pedersen OB,Jemec GB

更新日期：2019-12-01 00:00:00

abstract：:A sensitive and technically simple enzyme-linked immunosorbent assay (ELISA) was developed to demonstrate circulating IgA- and IgG-class antibodies to gliadin, a component of wheat gluten. Serum samples from 24 patients with dermatitis herpetiformis (DH), 5 with coeliac disease (CD) and 75 normal controls were analyse...

journal_title：Archives of dermatological research

authors： Vainio E,Kalimo K,Reunala T,Viander M,Palosuo T

更新日期：1983-01-01 00:00:00

abstract：:Oxidative stress may play a pivotal role in the pathogenesis of psoriasis, an inflammatory/hyperproliferative skin disease characterized by the cutaneous accumulation of neutrophils releasing reactive oxygen species, as revealed in a number of studies. This study was performed to demonstrate the presence of oxidative ...

journal_title：Archives of dermatological research

authors： Yazici C,Köse K,Utaş S,Tanrikulu E,Taşlidere N

更新日期：2016-04-01 00:00:00

abstract：:Total osmotic pressure does not differ significantly in suction blister fluid or in serum of healthy persons from blister fluid, suction blister fluid or serum of patients with dermatitis herpetiformis, bullous contact dermatitis and pemphigus vulgaris. The average values reach about 293 mOsmol/kg. This results from d...

journal_title：Archives of dermatological research

authors： Bork K

更新日期：1978-01-01 00:00:00

abstract：:Thymocyte selection-associated high-mobility group box (TOX) is aberrantly expressed in cutaneous T-cell lymphomas. In a recent study, TOX expression was noted unexpectedly in the follicle center (germinal center) B-cells of reactive lymph nodes and tonsils, used as external controls. To evaluate whether TOX is also e...

journal_title：Archives of dermatological research

authors： Schrader AM,Jansen PM,Willemze R

更新日期：2016-08-01 00:00:00

abstract：:Secretory component (SC) acts as a transmembrane polymeric immunoglobulin receptor of epithelial cells and is known to bind to polymeric IgA and to contribute to the secretion of secretory IgA (sIgA). We describe a new biological function for free SC (FSC) by which the expression of intercellular adhesion molecule-1 (...

journal_title：Archives of dermatological research

authors： Nihei Y,Maruyama K,Zhang JZ,Kobayashi K,Kaneko F

更新日期：1995-01-01 00:00:00

abstract：:Lichen planus (LP) is a chronic inflammatory, T cell-mediated autoimmune skin disease. Innate immunity could explain the interplay between environmental triggers and the autoimmune cascade leading to disease development. Toll-like receptors (TLRs) are important components of the innate immune system, with no previous ...

journal_title：Archives of dermatological research

authors： Salem SA,Abu-Zeid RM,Nada OH

更新日期：2013-03-01 00:00:00

abstract：:The present study aimed to observe the therapeutic effect of combined mizolastine and proteoglycan in chronic urticaria. The patients were randomly divided into the treatment group (n = 56) and the control group (n = 44). The treatment group was medicated with calcium gluconate (10 mg/ time, 1 time/day), vitamin D3 (i...

journal_title：Archives of dermatological research

authors： Xiong X,Song L,Chen F,Ma X

更新日期：2019-12-01 00:00:00

abstract：:In many skin diseases such as Demodex folliculitis, rosacea- or steroid-induced rosacea Demodex mites are present in abundance and are at least partially held responsible for causing these disorders. Although it is known that these diseases respond well to tetracyclines, it is unclear if this is due to the antiinflamm...

journal_title：Archives of dermatological research

authors： Borgo SN,Sattler EC,Hogardt M,Adler K,Plewig G

更新日期：2009-10-01 00:00:00

abstract：:The adenylate cyclase system of an established human trichilemmoma cell line was investigated. Stimulators of human epidermal adenylate cyclase system, epinephrine, histamine, adenosine, and prostaglandin E increased cyclic AMP levels of the trichilemmoma cells. The effects of epinephrine, histamine, and adenosine wer...

journal_title：Archives of dermatological research

authors： Tsutsui M,Iizuka H,Ohkawara A,Adachi K,Kanzaki T

更新日期：1987-01-01 00:00:00

abstract：:The mechanism of action of thalidomide in the treatment of patients with Behçet's disease (BD) is poorly understood. There is some evidence to suggest that certain immunological abnormalities are associated with the pathogenesis of BD. A BD-like mouse model induced by herpes simplex virus (HSV) inoculation shows simil...

journal_title：Archives of dermatological research

authors： Lee ES,Kim YA,Kwon HJ,Bang D,Lee S,Sohn S

更新日期：2004-09-01 00:00:00

abstract：:The pathogenetic mechanisms in vitiligo have not been completely clarified. One of the major hypotheses in the pathogenesis of vitiligo is the oxidative stress hypothesis. The active or stable phase of vitiligo is defined on the basis of the progression or appearance of new lesions in the last 3 months and the absence...

journal_title：Archives of dermatological research

authors： Ines D,Sonia B,Riadh BM,Amel el G,Slaheddine M,Hamida T,Hamadi A,Basma H

更新日期：2006-09-01 00:00:00