Allergic vasculitis. A histological and immunofluorescent study of lesional and non-lesional skin in relation to circulating immune complexes.

abstract：:Interleukin-17 (IL-17) has been implicated in the pathogenesis of a large number of inflammatory and autoimmune conditions, including skin disorders such as psoriasis. Recently, much data have accumulated on the possible role of IL-17 in the pathogenesis of alopecia areata (AA). In this review, the available informati...

journal_title：Archives of dermatological research

authors： Ramot Y,Marzani B,Pinto D,Sorbellini E,Rinaldi F

更新日期：2018-07-01 00:00:00

abstract：:Hand warts were studied in 160 butchers. Clinical and histological studies were performed in 190 warts and virological studies in 165 warts from 104 butchers. Since we found almost perfect correlation between the histological pattern and the type of infecting virus, it was possible to evaluate the virus types in a fur...

journal_title：Archives of dermatological research

authors： Jablońska S,Obalek S,Favre M,Golebiowska A,Croissant O,Orth G

更新日期：1987-01-01 00:00:00

abstract：:The incidence of epithelioid sarcoma among patients with malignant soft tissue tumors is small, but the rates of recurrence and metastasis of this type of sarcoma are high. To date, effective chemotherapy for advanced epithelioid sarcoma has not been established and, furthermore, epithelioid sarcoma is known to exhibi...

journal_title：Archives of dermatological research

authors： Kusakabe H,Iwasaki H,Sano K,Kiyokane K

更新日期：2000-06-01 00:00:00

abstract：:The mechanistic target of rapamycin (mTOR) is involved in the regulation of cellular growth, proliferation, lipid synthesis, and protein translation. The mTOR pathway involves two complexes: the mechanistic target of rapamycin complex 1 (mTORC1) and the mechanistic target of rapamycin complex 2 (mTORC2). Both mTOR com...

journal_title：Archives of dermatological research

authors： Leo MS,Sivamani RK

更新日期：2014-12-01 00:00:00

abstract：:Marie Unna Hereditary Hypotrichosis 1 (MUHH1; OMIM 146550), a rare monogenic condition characterized by the development of sparse, twisted hair or complete hair loss, is the consequence of mutations located in the hairless (HR) gene. We have identified a 68-year-old Hungarian woman affected by alopecia universalis and...

journal_title：Archives of dermatological research

authors： Farkas K,Nagy N,Kinyó A,Kemény L,Széll M

更新日期：2012-10-01 00:00:00

abstract：:Tranilast is used clinically as a drug for hypertrophic scars or keloids. Recently, the roles of keratinocytes in the pathogenesis of those conditions have been noted. Therefore, we first examined the effect of tranilast on the cell growth of normal human keratinocytes. A cell growth assay demonstrated that the cell n...

journal_title：Archives of dermatological research

authors： Kubo M,Zhao Y,Moriguchi T

更新日期：2012-11-01 00:00:00

abstract：:Recently, we described a novel fibroblast-restricted monoclonal antibody (mAb AS02) that recognizes a membrane-bound antigen. Characterization and isolation of the corresponding antigen showed that mAb AS02 recognized a protein on human fibroblasts that is highly homologous or identical to human Thy-1 antigen (CD90). ...

journal_title：Archives of dermatological research

authors： Saalbach A,Kraft R,Herrmann K,Haustein UF,Anderegg U

更新日期：1998-07-01 00:00:00

abstract：:Melanoma incidence in Australia remains the highest in the world; hence understanding its causation is paramount for future therapeutic developments. Multiple primary melanomas are also common occurrences among the Australian population with identified risk factors such as personal and family history of melanoma, fair...

journal_title：Archives of dermatological research

authors： Sinnya S,Jagirdar K,De'Ambrosis B,McMeniman E,Sturm RA,Soyer HP

更新日期：2015-10-01 00:00:00

abstract：:Patients with atopic dermatitis (AD) often present with dry skin, and the reduced secretion of sebum may be responsible for the impaired skin barrier function. A sebum check film enables the patient to self-evaluate the skin sebum content. This study compared the sebum check film with a sebumeter. The skin sebum conte...

journal_title：Archives of dermatological research

authors： Furuichi M,Makino T,Matsunaga K,Hamade E,Yokoi H,Shimizu T

更新日期：2010-11-01 00:00:00

abstract：:Genetic abnormalities for different subtypes of epidermolysis bullosa (EB) have been described. In dominant simplex type EB, mutations of the K5 or K14 gene lead to disruption of basal cells and the formation of bullae. The recessive simplex types include EB with muscular dystrophy due to abnormal plectin, EB without ...

journal_title：Archives of dermatological research

authors： Mitsuhashi Y,Hashimoto I

更新日期：2003-04-01 00:00:00

abstract：:Serotonin is a monoamine acting as a neuromediator in the central and peripheral nervous system. Recently, serotonin has also been shown to influence T- and B-cell function. The serotonin transporter is central in the regulation of the serotonergic system and widely expressed on cells of the immune system. A functiona...

journal_title：Archives of dermatological research

authors： Mössner R,Stiens G,König IR,Schmidt D,Platzer A,Krüger U,Reich K

更新日期：2009-07-01 00:00:00

abstract：:Interleukin-6-like (IL-6-like) immunoreactivity was sought in inflamed and normal human skin using the same immunohistochemical technique as for detection of neuropeptides. Such immunoreactivity was found in dermal and in a few intraepidermal nerve-like fibres in biopsy specimens from inflamed skin from patients with ...

journal_title：Archives of dermatological research

authors： Nordlind K,Chin LB,Ahmed AA,Brakenhoff J,Theodorsson E,Lidén S

更新日期：1996-07-01 00:00:00

abstract：:Paraneoplastic pemphigus patients (PNP) develop a group of autoantibodies, among which those against envoplakin and periplakin are almost always found. Epitope mapping has indicated that the linker subdomains of the proteins harbor the major antigenic sites recognized by PNP sera. In order to detect specific autoantib...

journal_title：Archives of dermatological research

authors： Huang Y,Li J,Zhu X

更新日期：2009-10-01 00:00:00

abstract：:The established mouse epidermis-derived cell line HEL/30 was incubated in the presence of 3H arachidonic acid (AA) for 1 h. After medium removal, cells were reincubated with fresh medium in the presence or absence of the calcium ionophore A23187 and tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate (TPA). The AA me...

journal_title：Archives of dermatological research

authors： Tragni E,Caruso D,Porta S,Fumagalli R,Galli G,Galli CL

更新日期：1988-01-01 00:00:00

abstract：:In a group of 40 patients suffering from wide-spread psoriasis oral administration of a retinoid (Ro 10-9359) was followed by PUVA therapy. The clearance rate was increased by 30% as compared to PUVA alone. Except for cheilitis no side effects were seen. Histological analysis in 20 patients before, during and after th...

journal_title：Archives of dermatological research

authors： Heidbreder G,Christophers E

更新日期：1979-05-04 00:00:00

abstract：:Pemphigus is a general term for a rare group of autoimmune diseases which result in the formation of blisters on the skin and oral cavity. Although there is no way to prevent autoimmune diseases, some factors may trigger pemphigus initiation in susceptible individuals or be exacerbated in affected patients. Recognitio...

journal_title：Archives of dermatological research

authors： Tavakolpour S

更新日期：2018-03-01 00:00:00

abstract：:Keloid disease (KD) is a quasineoplastic fibroproliferative tumour of unknown origin causing a progressive, recurrent dermal lesion. KD is not homogeneous in nature and shows phenotypic structural differences between its distinct peripheral margins compared to its centre. The keloid margin is often symptomatically mor...

journal_title：Archives of dermatological research

authors： Hollywood KA,Maatje M,Shadi IT,Henderson A,McGrouther DA,Goodacre R,Bayat A

更新日期：2010-12-01 00:00:00

abstract：:An ultrastructural investigation of two cutaneous lesions in a two-year-old Turkish boy with disseminated lipogranulomatosis (Farber) revealed curvilinear bodies in fibroblasts, histiocytes, and endothelial cells; "elongated membranes" in fibroblasts and endothelial cells; "zebra bodies" in endothelial cells; and spin...

journal_title：Archives of dermatological research

authors： Schmoeckel C,Hohlfed M

更新日期：1979-10-01 00:00:00

abstract：:The pathomorphological and pathophysiological reactions of the first skincycle of the mutant (Ng) were histologically investigated. 1. During the hair growth disturbances as the result of imperfect keratinisation changes of the morphology and function of different skin areas could be observed. 2. The developments of a...

journal_title：Archives of dermatological research

authors： Franz E,Bosse K,Kreutzer E

更新日期：1978-06-29 00:00:00

abstract：:This study was designed in order to prove on a large-scale basis the efficacy of oral photochemotherapy (PUVA) in the prevention of polymorphous light eruption (PLE), to work out indication criteria for PUVA treatment of this disease, and to establish a simple method based on anamnestic data to differentiate UVA from ...

journal_title：Archives of dermatological research

authors： Gschnait F,Schwarz T,Ladich I

更新日期：1983-01-01 00:00:00

abstract：:Atopic dermatitis (AD) is a frequent and burdensome disease. The objectives of this study were (1) to assess the willingness to pay (WTP) and quality of life (Qol) in AD patients and (2) to compare the results with data on other chronic skin diseases. To collect data, a non-interventional, cross-sectional nationwide p...

journal_title：Archives of dermatological research

authors： Beikert FC,Langenbruch AK,Radtke MA,Kornek T,Purwins S,Augustin M

更新日期：2014-04-01 00:00:00

abstract：:Propylene glycol (propane-1,2-diol) is the only diol widely used in dermatology. Pentane-1,5-diol is mainly used as a plasticizer in cellulose products and adhesives, in dental composites and in brake fluid compositions and as a preservative for grain. However, pentane-1,5-diol is also an effective solvent, water-bind...

journal_title：Archives of dermatological research

authors： Faergemann J,Wahlstrand B,Hedner T,Johnsson J,Neubert RH,Nyström L,Maibach H

更新日期：2005-12-01 00:00:00

abstract：:Vitiliginous patients undergoing photochemotherapy with TMP were less susceptible to a sun burn. To investigate this point, the MED for UV-B was measured before, 2 h, and 24 h after oral intake of TMP in 10 healthy volunteers. There was an increase of MED when UV exposure had taken place 2 h after TMP intake (P < 0.01...

journal_title：Archives of dermatological research

authors： Agache PG,Coupez L

更新日期：1980-01-01 00:00:00

abstract：:We have observed that lipopolysaccharide (LPS) induces pigmentation in melanocytes and in this study have examined whether these responses are mediated by the p38 mitogen-activated protein kinase (MAPK) signaling pathway. LPS appears to stimulate the pigmentation of melanocytes and cultured skin. LPS was found to indu...

journal_title：Archives of dermatological research

authors： Ahn JH,Jin SH,Kang HY

更新日期：2008-07-01 00:00:00

abstract：:Female hairless mice (strain mutant hr/hr) have been irradiated with increasing doses of UV-B over a period of 4 weeks. They were compared with untreated controls Additional groups of 30 mice were treated with milk base or cream base or milk SPF6 or cream SPF6 or cream SPF8 daily before irradiation. No changes of body...

journal_title：Archives of dermatological research

authors： Vogel HG,Alpermann HG,Futterer E

更新日期：1981-01-01 00:00:00

abstract：:Histochemical findings of primary and metastatic amelanotic melanomas were shown by the formaldehyde-induced fluorescence method (Falck and Hillarp). All or some of the amelanotic melanoma cells were discovered to emit green specific fluorescence. Results of the determination of 5-S-cysteinyldopa and DOPA in amelanoti...

journal_title：Archives of dermatological research

authors： Morishima T,Tatsumi F,Fukada E,Watanabe M,Nagashima N,Hanawa S

更新日期：1983-01-01 00:00:00

abstract：:Atopic dermatitis (AD) can be exacerbated by various factors, including emotional stress, scratching and sweating. The aim of the present study was to evaluate the hypothesis that the inflammatory reaction in AD is also neurogenic. For this purpose, the levels of vasoactive intestinal polypeptide were measured radioim...

journal_title：Archives of dermatological research

authors： Pincelli C,Fantini F,Romualdi P,Lesa G,Giannetti A

更新日期：1991-01-01 00:00:00

abstract：:In the case of viral acanthomas, the stratum spinosum and granulosum presents ballooned cells which contain all transitional stages from multivesicular bodies (MVB) to keratinosomes. A particularity in condylomata acuminata are the "wagon-wheel" bodies. These structures are typical for the non keratinazed squamous epi...

journal_title：Archives of dermatological research

authors： Heine H,Schaeg G,Nasemann T

更新日期：1978-01-01 00:00:00

abstract：:Stratum corneum forms the UV barrier. The effect of ultraviolet B (UVB) on normal skin was extensively studied; however, its effect on barrier perturbed skin remains undefined. Both barrier perturbation and UVB irradiation induce endoplasmic reticulum (ER) stress and unfolded protein response (UPR) in keratinocytes. M...

journal_title：Archives of dermatological research

authors： Lee SE,Takagi Y,Nishizaka T,Baek JH,Kim HJ,Lee SH

更新日期：2017-09-01 00:00:00

abstract：:Epidermolytic hyperkeratosis (EH) is a genetic disorder of keratins associated with epidermal differentiation. Affected individuals carry gene mutations for conserved sequences of keratins K1 or K10. The structural alterations of tonofilaments in EH seem to be a direct consequence of the keratin gene mutations. EH epi...

journal_title：Archives of dermatological research

authors： Ishida-Yamamoto A,Iizuka H,Manabe M,O'Guin WM,Hohl D,Kartasova T,Kuroki T,Roop DR,Eady RA

更新日期：1995-01-01 00:00:00