Abstract:
:Pemphigus is a general term for a rare group of autoimmune diseases which result in the formation of blisters on the skin and oral cavity. Although there is no way to prevent autoimmune diseases, some factors may trigger pemphigus initiation in susceptible individuals or be exacerbated in affected patients. Recognition of these triggers, based on the latest studies and experiences is essential and should be updated every few years. In this study, several triggers, including different drugs and treatments, diseases, vaccines, genetic factors, nutrients, micronutrients, pregnancy, stress, and various other triggers have been discussed. Some possible triggers, such as blood antigens and the effect of seasons have also been discussed briefly. Moreover, some protective factors against pemphigus have been reviewed. Considering the molecular mechanism of pemphigus and immune response alteration during this disease, some possible triggers have been suggested and discussed. Although those triggers may be a real threat, more studies are needed to support these hypotheses.
journal_name
Arch Dermatol Resjournal_title
Archives of dermatological researchauthors
Tavakolpour Sdoi
10.1007/s00403-017-1790-8subject
Has Abstractpub_date
2018-03-01 00:00:00pages
95-106issue
2eissn
0340-3696issn
1432-069Xpii
10.1007/s00403-017-1790-8journal_volume
310pub_type
杂志文章,评审abstract::The cellular origin of Merkel cell carcinoma (MCC) is controversial. We previously hypothesized that MCC originates from hair follicle stem cells or Merkel cell (MC) progenitors residing within the hair follicle bulge. Examination of three cases of combined MCC led to the unexpected discovery that numerous keratin 20 ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-018-1877-x
更新日期:2019-01-01 00:00:00
abstract::This study was designed to investigate the effects of griseofulvin, 5-fluorocytosine (5-FC), and amphotericin B on pancreatic and gastric secretion after the administration of a single large dose, or repeated small doses for 3 weeks, in male albino rats. The exocrine functions of the main digestive glands were only sl...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00694617
更新日期:1979-10-01 00:00:00
abstract::Three per cent boric acid incorporated in an anhydrous, water-emulsifying ointment causes no increase of boron levels in blood and urine during a period of 1-9 days after a single topical application. The same amount of boric acid incorporated in a water-based jelly does cause an increase in blood and urine levels, be...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00510389
更新日期:1982-01-01 00:00:00
abstract::In the case of viral acanthomas, the stratum spinosum and granulosum presents ballooned cells which contain all transitional stages from multivesicular bodies (MVB) to keratinosomes. A particularity in condylomata acuminata are the "wagon-wheel" bodies. These structures are typical for the non keratinazed squamous epi...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::In preparations of papillary dermis taken from clinically normal skin of patients with dermatitis herpetiformis (DH), the disappearance of granular IgA deposits induced by peptic digestion was partial at pH 4.5 and total at pH 4.1, as visualized by immunofluorescence microscopy. In a model system in which human monome...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00412495
更新日期:1985-01-01 00:00:00
abstract::This study uses light and electron microscopes to gain a better knowledge of the interactions of calcium hydroxylapatite filler with the connective tissue of the skin and the modifications of the human deep dermis, after 2 months of treatment. Some morphological evidences of this observational study of filler treated ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-017-1734-3
更新日期:2017-07-01 00:00:00
abstract::There are differences concerning reported mortality rates and prognostic factors of bullous pemphigoid (BP) patients in different studies. Our objectives were to evaluate the mortality rates and prognostic factors among Israeli BP patients compared to matched control subjects. Three age- and sex-matched patients witho...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-018-1875-z
更新日期:2019-01-01 00:00:00
abstract::The aim of this study was to screen the antioxidant, anti-hyaluronidase, and anti-elastase activity of the lyophilized juice of Cucumis sativus fruit (CSLJ). The CSLJ was subjected to DPPH and superoxide radical scavenging assay in reference to butylated hydroxytoluene. The hyaluronidase and elastase inhibitory assay ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-010-1103-y
更新日期:2011-05-01 00:00:00
abstract::Because of its easy accessibility, the skin is a very attractive target for gene therapy purposes. To study potential clinical applications in a preclinical setting, appropriate animal models are needed. Pig skin is very similar to human skin, and a variety of human diseases that are potentially amenable to gene thera...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-006-0653-5
更新日期:2006-06-01 00:00:00
abstract::The function of microphages has been studied in two patients with chronic pyoderma vegetans by in vitro determination of phagocytosis as well as chemotaxis. The results showed a striking decrease in the chemotactic activity of the neutrophil granulocytes, a reduced phagocytosis of Candida albicans and Staphylococcus a...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::A recently described endogenous proteolytic process in pieces of human plantar stratum corneum incubated in vitro has been further studied. This process leads to a decrease in cohesion between the cells that had been facing outwards in vivo. Using two methods, that differed with respect to efficiency, to detach surfac...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00371642
更新日期:1990-01-01 00:00:00
abstract::Adult female Wistar rats (n = 48) divided into four groups of 12 were treated orally with 3 mg/kg per day thalidomide, a 0.05% hexachlorobenzene (HCB)--containing diet, with both drugs together and with the vehicles (controls) over periods of 10 and 60 days. The protein and P450 contents and the activities of aminopyr...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00402227
更新日期:1994-01-01 00:00:00
abstract::It has been reported that artificial restoration of barrier function by a water vapor-impermeable membrane after tape stripping induces barrier abrogation in hairless mice, impeding rather than enhancing barrier recovery. To address this issue, we examined the morphologic changes in the epidermis after tape stripping ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050280
更新日期:1998-03-01 00:00:00
abstract::GM-CSF is known primarily as a hematopoietic growth factor, but it has also been shown to inhibit mast cell differentiation in vitro. In order elucidate the mechanisms involved, we investigated the effects of GM-CSF in vitro on the differentiation of human leukemic mast cells (HMC-1 cells) and normal cord blood-derive...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030100225
更新日期:2001-05-01 00:00:00
abstract::To elucidate the interaction between melanoma and its matrix, we cultured B16 murine melanoma cells on and in type I collagen gel and evaluated specified functions of melanoma cells; tyrosinase activity and melanin-synthesizing capacity. Proliferation of cells cultured in these environments was markedly suppressed com...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00371647
更新日期:1990-01-01 00:00:00
abstract::Costimulation of anti-CD3-triggered proliferative T-cell responses by type I and type IV collagen and fibronectin was studied in 25 patients with psoriasis and 12 healthy subjects. The stimulation index of anti-CD3-mediated responses in the presence of type I collagen was about half that in the controls. Although the ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF01262328
更新日期:1995-01-01 00:00:00
abstract::Recently a new thin layer chromatography plate (Whatman LK 6D) became available which is extremely easy to handle and permits highly reproducible qualitative and quantitative analysis. This plate proved to be of great value for the investigation of skin surface lipids. The use of a fatty acid methyl ester as an intern...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00412383
更新日期:1979-07-30 00:00:00
abstract::The expression and location of the Ki-67 antigen was investigated in 62 basal cell carcinomas (BCC) using immunostaining techniques (PAP and APAAP) on cryostat sections. The tumor samples were classified into three groups according to microarchitecture (nodular, superficial or fibrosing). The Ki-67 growth fraction dis...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00371599
更新日期:1993-01-01 00:00:00
abstract::Photodynamic therapy (PDT) in dermatology has been proven to be a successful noninvasive therapeutic modality for treating skin cancer. To facilitate its clinical introduction, the development of topical photosensitizers is necessary to avoid generalized, cutaneous photosensitivity. Therefore the penetration of synthe...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050168
更新日期:1997-02-01 00:00:00
abstract::Studies aimed at understanding the pathology, genetics, and therapeutic response of vitiligo rely on asking a single question about 'physician-diagnosed' vitiligo on surveys to identify subjects for research. However, this type of self-reporting is not sufficient. Our objective was to determine if the patient-administ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-014-1515-1
更新日期:2015-01-01 00:00:00
abstract::Numerous reports have shown that psoriasis is associated with obesity and leptin. However, few reports are available on the association between serum leptin levels and leptin gene expression in SAT of psoriasis patients. To clarify this point, we examined serum leptin levels and expression levels of leptin messenger R...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-015-1581-z
更新日期:2015-08-01 00:00:00
abstract::Eighteen patients with atopic dermatitis were randomly chosen for a clinical trial to compare the action of the H2 receptor antagonist cimetidine in combination with the H1 receptor antagonist chorpheniramine against the chlorpheniramine alone and against placebo. Each treatment period lasted for 4 weeks. Intensity of...
journal_title:Archives of dermatological research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00412560
更新日期:1984-01-01 00:00:00
abstract::A significant difference between keloids and hypertrophic scars could be demonstrated by means of acid elution of lymphoid blood cells and immunofluorescence studies. A total of 20 patients (13 patients with keloids and seven with hypertrophic scars) were investigated. All the 13 patients with keloids revealed in the ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00403728
更新日期:1982-01-01 00:00:00
abstract::Female hairless mice (strain mutant hr/hr) have been irradiated with increasing doses of UV-B over a period of 4 weeks. They were compared with untreated controls Additional groups of 30 mice were treated with milk base or cream base or milk SPF6 or cream SPF6 or cream SPF8 daily before irradiation. No changes of body...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00403786
更新日期:1981-01-01 00:00:00
abstract::Mite antigens play important roles in the pathogenesis of atopic dermatitis (AD). We recently developed a novel air cleaner (KC-850U) using charged plasma cluster ions to eliminate a variety of allergens from house environments. The present work demonstrates the ability of KC-850U to decrease the symptoms of AD induce...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-010-1095-7
更新日期:2011-07-01 00:00:00
abstract::Scleroderma is a heterogeneous disease with a complex etiology. As more information is gained about the underlying mechanisms and the improved classifications of scleroderma subtypes, treatments can be better personalized. Improving scleroderma patients' early diagnosis before end organ manifestations occur should imp...
journal_title:Archives of dermatological research
pub_type: 杂志文章,评审
doi:10.1007/s00403-016-1647-6
更新日期:2016-09-01 00:00:00
abstract::The stratum corneum, which is the outermost layer of the skin, functions as an important barrier to maintain biological homeostasis. The multilamellar structures formed by intercellular lipids present in the stratum corneum are considered to play an important role in barrier function. Most intercellular lipids are unb...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030000160
更新日期:2000-09-01 00:00:00
abstract::Classic Refsum disease (RD) is a rare, autosomal recessively-inherited disorder of peroxisome metabolism due to a defect in the initial step in the alpha oxidation of phytanic acid (PA), a C16 saturated fatty acid with four methyl side groups, which accumulates in plasma and lipid enriched tissues (please see van den ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-014-1478-2
更新日期:2014-10-01 00:00:00
abstract::Stratum corneum forms the UV barrier. The effect of ultraviolet B (UVB) on normal skin was extensively studied; however, its effect on barrier perturbed skin remains undefined. Both barrier perturbation and UVB irradiation induce endoplasmic reticulum (ER) stress and unfolded protein response (UPR) in keratinocytes. M...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-017-1753-0
更新日期:2017-09-01 00:00:00
abstract::In 8 patients with idiopathic chronic urticaria suction blisters were produced simultaneously on lesional and perilesional skin in the periumbilical area without application of heat. The suction pressure was 250 mm Hg, and thus the blister production lasted from 60--120 min. The blister fluid histamine was determined ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00418572
更新日期:1979-11-01 00:00:00