Lichen planus, chronic liver diseases, and immunologic involvement.

abstract：:Genetic abnormalities for different subtypes of epidermolysis bullosa (EB) have been described. In dominant simplex type EB, mutations of the K5 or K14 gene lead to disruption of basal cells and the formation of bullae. The recessive simplex types include EB with muscular dystrophy due to abnormal plectin, EB without ...

journal_title：Archives of dermatological research

authors： Mitsuhashi Y,Hashimoto I

更新日期：2003-04-01 00:00:00

abstract：:Exposure in utero has been suggested to influence health later in life. The aim of this study was to investigate, if the use of prenatal food supplements was associated with atopic dermatitis in the offspring. Mothers who gave birth in the hospital G. B. Grassi were invited to participate in the study (n = 395). Infor...

journal_title：Archives of dermatological research

authors： Fortes C,Mastroeni S,Mannooranparampil TJ,Di Lallo D

更新日期：2019-07-01 00:00:00

abstract：:In skin inflammation, vascular endothelial growth factor (VEGF) and CXCL-8/IL-8 play an important role and are produced by activated keratinocytes. Extracts from Ginkgo biloba leaves (GBE), widely used in phytotherapy, have been reported to exert antioxidant and anti-inflammatory properties in the skin. We therefore e...

journal_title：Archives of dermatological research

authors： Trompezinski S,Bonneville M,Pernet I,Denis A,Schmitt D,Viac J

更新日期：2010-04-01 00:00:00

abstract：:Results of previous investigations have indicated that photochemotherapy (PUVA) attacks membranes of target cells. Using the combination of a stopped-flow technique and laser irradiation we were able to prove that the fast PUVA effect is explainable solely by the membrane damage. Lymphoid cells of healthy persons or p...

journal_title：Archives of dermatological research

authors： Böhm F,Meffert H,Bauer E

更新日期：1986-01-01 00:00:00

abstract：:One of the primary events in the pathogenesis of acne vulgaris is abnormal follicular keratinization. Since oral isotretinoin therapy reduces follicular hyperkeratinization in acne, our study has been designed to determine whether epidermal lipid composition of the epithelium of sebaceous follicles is affected by isot...

journal_title：Archives of dermatological research

authors： Melnik B,Kinner T,Plewig G

更新日期：1988-01-01 00:00:00

abstract：:Vitiligo is an acquired depigmentary disorder of the skin, characterized by incomplete penetrance, multiple susceptibility loci and genetic heterogeneity. An immunologic hypothesis is currently advanced as a possible pathogenesis of vitiligo. The cytokines have an important role in pathogenesis of autoimmunity in whic...

journal_title：Archives of dermatological research

authors： Yazici AC,Erdal ME,Kaya TI,Ikizoglu G,Savasoglu K,Camdeviren H,Tursen U

更新日期：2006-06-01 00:00:00

abstract：:Typical confluent lesions of lichen planus were transplanted onto nude mice and cultured in organ culture. The characteristic histologic appearance of lichen planus disappeared after grafting and became similar to normal skin within 6 weeks on nude mice; the dense lymphocyte infiltrate in dermis disappeared, the basal...

journal_title：Archives of dermatological research

authors： Tammi R,Hyyryläinen A,Fräki JE

更新日期：1988-01-01 00:00:00

abstract：:A monoclonal antibody (Ted-R-1) to the keratohyalin granules (KHGs) of the newborn rat epidermis was developed by immunizing mice with a pH 4.7 hematoxylin-stainable fraction of the extract in a 50 mM Tris-HCl buffer, pH 7.3, containing 10 micrograms/ml phenylmethylsulfonyl fluoride (PMSF) from the newborn rat whole e...

journal_title：Archives of dermatological research

authors： Tezuka T,Takahashi M

更新日期：1989-01-01 00:00:00

abstract：:Studies have identified increased prevalence of vitamin D deficiency in patients with alopecia areata (AA), an autoimmune disease characterized by hair loss, but none have prospectively examined vitamin D status and incident AA. In 55,929 women in the Nurses' Health Study (NHS), we prospectively evaluated the associat...

journal_title：Archives of dermatological research

authors： Thompson JM,Li T,Park MK,Qureshi AA,Cho E

更新日期：2016-11-01 00:00:00

abstract：:The history of 188 caucasian patients with atopic dermatitis (AD) and of 2,151 family members has been analyzed. Of the AD patients 48% suffered from respiratory atopy (36% rhinitis, 28% asthma, and 15% both). AD showed by far the earliest onset of all atopic diseases: 50% of our patients had skin lesions before the a...

journal_title：Archives of dermatological research

authors： Küster W,Petersen M,Christophers E,Goos M,Sterry W

更新日期：1990-01-01 00:00:00

abstract：:Acidic polysaccharides (AP) are released from Propionibacterium acnes I and II during growth. Similar antigens are released from two strains of P. avidum, but in a smaller amount. Furthermore, prostaglandin-like substances (PLS) have been isolated from the lipid fraction of P. acnes. The AP antigens give rise to a pre...

journal_title：Archives of dermatological research

authors： Dalen A,Hellgren L,Iversen OJ,Vincent J

更新日期：1980-01-01 00:00:00

abstract：:The presence, distribution and cellular localization of tumour necrosis factor-alpha (TNF alpha) were investigated in normal human and murine epidermis using immunohistological and immunoelectron microscopic methods with monoclonal and polyclonal antibodies. The immunostaining revealed an intercellular plasma membrane...

journal_title：Archives of dermatological research

authors： Kolde G,Schulze-Osthoff K,Meyer H,Knop J

更新日期：1992-01-01 00:00:00

abstract：:To find novel depigmenting agents, a new synthetic compound, N-adamantyl-3,4-dihydroxybenzamide (NADB) was produced and the effects on melanogenesis were investigated. Our results showed that NADB reduced melanin synthesis in a dose-dependent manner in melan-a cells. Tyrosinase activity was also reduced by NADB treatm...

journal_title：Archives of dermatological research

authors： Rho HS,Ahn SM,Hwang JS

更新日期：2011-04-01 00:00:00

abstract：:Leprosy is a curable disease with well-defined etiology, but lacks better diagnostic tools, preventive and therapeutic strategies. The continued application of the Ridley-Jopling clinical classification that recognizes the natural diversity of the immune response has provided the basis for understanding leprosy, and t...

journal_title：Archives of dermatological research

authors： Goulart IM,Goulart LR

更新日期：2008-07-01 00:00:00

abstract：:Diabetic foot ulcers (DFUs) are chronic wounds with high matrix metalloproteinase (MMP) activity, and are a frequent complication on diabetics. This work studied the expression of selected MMP and tissue inhibitor of metalloproteinases (TIMP) gene family members in DFU and normal skin biopsies, and in vitamin D-treate...

journal_title：Archives of dermatological research

authors： López-López N,González-Curiel I,Treviño-Santa Cruz MB,Rivas-Santiago B,Trujillo-Paez V,Enciso-Moreno JA,Serrano CJ

更新日期：2014-11-01 00:00:00

abstract：:As the main nitrogen source in Malassezia furfur, tryptophan induces the formation of fluorochromes and pigments, which make the yeast less sensitive to UV light. To detect a chemical UV filter, M. furfur (CBS 1878) was incubated at 30 degrees C for 14 days on a pigment-inducing medium and agar extracts were purified ...

journal_title：Archives of dermatological research

authors： Mayser P,Schäfer U,Krämer HJ,Irlinger B,Steglich W

更新日期：2002-05-01 00:00:00

abstract：:Reactive oxygen species (ROS) play important roles in the process of ultraviolet-induced skin damage or photoaging. Although many enzymatic and chemical methods have been developed for evaluating ROS, evaluation methods for ROS generation in living systems are quite limited. Here we propose a unique system to visualiz...

journal_title：Archives of dermatological research

authors： Hakozaki T,Date A,Yoshii T,Toyokuni S,Yasui H,Sakurai H

更新日期：2008-04-01 00:00:00

abstract：:To evaluate the proliferative activity of benign, borderline and malignant cutaneous melanocytic neoplasms, 30 cases of malignant melanoma (MM) and 41 cases of naevi were studied by immunostaining using a monoclonal antibody against proliferating cell nuclear antigen (PCNA). PCNA is a nuclear antigen expressed in the ...

journal_title：Archives of dermatological research

authors： Tokuda Y,Mukai K,Matsuno Y,Furuya S,Shimosato Y,Takasaki Y,Saida T,Ishihara K

更新日期：1992-01-01 00:00:00

abstract：:The roles of androgen hypersecretion, in situ enzyme activity, and androgen receptors in androgenetic alopecia in women are still a matter of debate. We studied 187 women with alopecia, which we graded I, II, or III, according to Ludwig's classification, and 21 healthy control women. All participants were subjected to...

journal_title：Archives of dermatological research

authors： Vexiau P,Chaspoux C,Boudou P,Fiet J,Abramovici Y,Rueda MJ,Hardy N,Reygagne P

更新日期：2000-12-01 00:00:00

abstract：:The pathomorphological and pathophysiological reactions of the first skincycle of the mutant (Ng) were histologically investigated. 1. During the hair growth disturbances as the result of imperfect keratinisation changes of the morphology and function of different skin areas could be observed. 2. The developments of a...

journal_title：Archives of dermatological research

authors： Franz E,Bosse K,Kreutzer E

更新日期：1978-06-29 00:00:00

abstract：:Previous studies have demonstrated that permeability barrier disruption by acetone treatment significantly enhances skin permeability to both hydrophilic and amphipathic compounds, but not to highly lipophilic compounds. The purpose of the present study was to investigate the dependence of permeability on molecular we...

journal_title：Archives of dermatological research

authors： Tsai JC,Hung PL,Sheu HM

更新日期：2001-06-01 00:00:00

abstract：:Human alpha 1(I) and alpha 1(III) procollagen mRNA expression in skin tissue from 15 systemic sclerosis (SSc) patients and from 7 normal control subjects was quantitatively analyzed using in situ hybridization. The grains accumulating in each area, representing procollagen mRNA expression per cell, were counted. To no...

journal_title：Archives of dermatological research

authors： Ohtsuka T,Koibuchi N,Sakai H,Yamakage A,Yamazaki S

更新日期：1999-11-01 00:00:00

abstract：:Tropospheric ozone (O3) is a source of oxidative stress. This study examined the ability of a topical antioxidant (WEL-DS) to inhibit O3-mediated damage in a human epidermal skin model. Four groups of tissues (N = 24) were compared: Group 1 (control) were untreated and unexposed; Group 2 were untreated and exposed to ...

journal_title：Archives of dermatological research

authors： Pecorelli A,McDaniel DH,Wortzman M,Nelson DB

更新日期：2020-05-08 00:00:00

abstract：:Adult female Wistar rats (n = 48) divided into four groups of 12 were treated orally with 3 mg/kg per day thalidomide, a 0.05% hexachlorobenzene (HCB)--containing diet, with both drugs together and with the vehicles (controls) over periods of 10 and 60 days. The protein and P450 contents and the activities of aminopyr...

journal_title：Archives of dermatological research

authors： Tsambaos D,Bolsen K,Georgiou S,Monastirli A,Goerz G

更新日期：1994-01-01 00:00:00

abstract：:The composition of the aerobic and anaerobic bacterial skin flora was investigated quantitatively and qualitatively in 25 patients with seborrheic eczema (SE) and in 35 healthy persons. In SE patients, the geometric mean count for propionibacteria in the pilosebaceous ducts of the forehead was reduced to a statistical...

journal_title：Archives of dermatological research

authors： Höffler U,Gloor M,Peters G,Ko HL,Bräutigan A,Thurn A,Pulverer G

更新日期：1980-01-01 00:00:00

abstract：:Plectin, a widespread cytoskeletal linker protein, is prominently expressed in basal keratinocytes of the epidermis. HD1, originally identified as a hemidesmosomal protein, has been suggested to be an isoform of or closely related to plectin, but the exact relationship between these proteins is unknown. Plectin has re...

journal_title：Archives of dermatological research

authors： Shimizu H,Masunaga T,Kurihara Y,Owaribe K,Wiche G,Pulkkinen L,Uitto J,Nishikawa T

更新日期：1999-10-01 00:00:00

abstract：:Recent studies have demonstrated that tumor necrosis factor-alpha (TNF-alpha) selectively decreases production of collagens I and III, the major types of collagen in the dermis, and increases production of collagenase in cultured dermal fibroblasts. The effects of TNF-alpha on collagens I, III and VI, fibronectin and ...

journal_title：Archives of dermatological research

authors： Takeda K,Hatamochi A,Arakawa M,Ueki H

更新日期：1993-01-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is believed to play a crucial role in neoplastic angiogenesis. Although the genetic background of basal cell carcinoma (BCC) has been analyzed in some papers, the mechanism of BCC pathogenesis is not fully understood. To the best of our knowledge, VEGF gene polymorphisms have ...

journal_title：Archives of dermatological research

authors： Sobjanek M,Zabłotna M,Lesiak A,Michajłowski I,Szczerkowska-Dobosz A,Sokolowska-Wojdylo M,Nowicki R

更新日期：2014-08-01 00:00:00

abstract：:Bullous pemphigoid (BP) is an autoimmune blistering skin disease associated with autoantibodies against two hemidesmosomal proteins, BP180 (type XVII collagen) and BP230. As the pathogenic relevance of antibodies against the immunodominant NC16A domain of BP180 has been clearly demonstrated, specific removal of these ...

journal_title：Archives of dermatological research

authors： Mersmann M,Dworschak J,Ebermann K,Komorowski L,Schlumberger W,Stöcker W,Zillikens D,Probst C,Schmidt E

更新日期：2016-01-01 00:00:00

abstract：:The use of microalgae in the skin care market is already established although the scientific rationale for their benefit was not clearly defined. In this work, the biological activities of dermatologic interest of the water extract from the microalga Botryococcus braunii (BBWE) were evaluated by a battery of in vitro ...

journal_title：Archives of dermatological research

authors： Buono S,Langellotti AL,Martello A,Bimonte M,Tito A,Carola A,Apone F,Colucci G,Fogliano V

更新日期：2012-11-01 00:00:00