Autoradiographic and planimetric analyses of the inflammatory infiltrate in psoriatic lesions under PUVA-therapy.

abstract：:In 8 patients with idiopathic chronic urticaria suction blisters were produced simultaneously on lesional and perilesional skin in the periumbilical area without application of heat. The suction pressure was 250 mm Hg, and thus the blister production lasted from 60--120 min. The blister fluid histamine was determined ...

journal_title：Archives of dermatological research

authors： Bork K,König W,Böhm G

更新日期：1979-11-01 00:00:00

abstract：:Melanoma in situ (MIS) is a form of radial growth phase melanoma in which the proliferation of malignant cells is confined to the epidermis. Histologic features are invaluable in recognition of MIS. Regression occurs when the host's immune system attacks the primary melanocytic tumor cells via tumor infiltrate lymphoc...

journal_title：Archives of dermatological research

authors： Cartron AM,Aldana PC,Khachemoune A

更新日期：2020-07-06 00:00:00

abstract：:Keloid is a fibrotic disease characterized by abnormal accumulation of extracellular matrix (ECM) in the dermis. It is a late spreading skin overgrowth and may be considered a plastic surgeon's nightmare. In nature, curcuminoid is composed of curcumin, demethoxycurcumin (DMC) and bisdemethoxycurcumin (bDMC). Curcumino...

journal_title：Archives of dermatological research

authors： Hsu YC,Chen MJ,Yu YM,Ko SY,Chang CC

更新日期：2010-12-01 00:00:00

abstract：:In the study described here we investigated the possibility of an association between the aggressiveness of melanoma and multidrug resistance phenotype by analyzing the expression and activity of P-glycoprotein (Pgp) in two genetically related transplantable hamster melanomas--a melanotic (Ma) and an amelanotic (Ab) f...

journal_title：Archives of dermatological research

authors： Witkowski JM,Kozłowska K,Zarzeczna M

更新日期：2000-07-01 00:00:00

abstract：:The safety and efficacy of imiquimod 5% cream is being evaluated for the treatment of dysplastic lesions of the epidermis (actinic keratoses, AK). The objective of this clinical study was to describe the pharmacokinetics and safety of topical imiquimod during multiple dosing of AK subjects. A total of 58 adult subject...

journal_title：Archives of dermatological research

authors： Harrison LI,Skinner SL,Marbury TC,Owens ML,Kurup S,McKane S,Greene RJ

更新日期：2004-06-01 00:00:00

abstract：:Nowadays, there is a great attention to the plasma applications in medicine. Not only does cold atmospheric pressure plasma provide a therapeutic opportunity to control redox-based processes, it is also an innovative method in rejuvenation. Given the current interest in new methods of rejuvenation, we aimed to introdu...

journal_title：Archives of dermatological research

authors： Babossalam S,Abdollahimajd F,Aghighi M,Mahdikia H,Dilmaghanian A,Toossi P,Shokri B

更新日期：2020-07-01 00:00:00

abstract：:As congenital nevocytic nevi have an increased risk of malignant degeneration, nevus-cell involvement in blood vessels and lymphatics is of particular interest. The present histological and ultrastructural studies revealed nevus-cell nests in the walls of venules in 1 out of 11 patients with medium-sized nevi, and in ...

journal_title：Archives of dermatological research

authors： Schneider BV,Maie O

更新日期：1985-01-01 00:00:00

abstract：:Recent studies revealed the cooperation between peroxisome proliferator-activated receptor gamma (PPARγ) and α-MSH signaling, which results in enhanced melanogenesis in melanocytes and melanoma cells. However, the agonists of PPARα, such as fenofibrate, exert depigmenting effect. Therefore, we aimed to check how the P...

journal_title：Archives of dermatological research

authors： Grabacka M,Wieczorek J,Michalczyk-Wetula D,Malinowski M,Wolan N,Wojcik K,Plonka PM

更新日期：2017-04-01 00:00:00

abstract：:In a group of 40 patients suffering from wide-spread psoriasis oral administration of a retinoid (Ro 10-9359) was followed by PUVA therapy. The clearance rate was increased by 30% as compared to PUVA alone. Except for cheilitis no side effects were seen. Histological analysis in 20 patients before, during and after th...

journal_title：Archives of dermatological research

authors： Heidbreder G,Christophers E

更新日期：1979-05-04 00:00:00

abstract：:A novel point mutation in a patient with vascular type Ehlers-Danlos syndrome is herein reported. The patient experienced pneumothorax and multiple arterial troubles during the past 10 years. The patient's hand skin was atrophic, and a paper-like atrophic scar was seen. The collagen microfibrils from the patient's ski...

journal_title：Archives of dermatological research

authors： Okamoto O,Ando T,Watanabe A,Sato F,Mimata H,Shimada T,Fujiwara S

更新日期：2008-10-01 00:00:00

abstract：:Recently a new thin layer chromatography plate (Whatman LK 6D) became available which is extremely easy to handle and permits highly reproducible qualitative and quantitative analysis. This plate proved to be of great value for the investigation of skin surface lipids. The use of a fatty acid methyl ester as an intern...

journal_title：Archives of dermatological research

authors： Weissmann A

更新日期：1979-07-30 00:00:00

abstract：:A procedure measuring the ornithine decarboxylase (ODC) activity and polyamine formation of intact neonatal mouse epidermal cells in culture has been developed and tested. Basal cells prepared from neonatal mouse epidermis were plated on round 15-mm Lux coverslips, placed in Costar 24 well culture clusters and grown a...

journal_title：Archives of dermatological research

authors： Roseeuw DI,Duell EA,Marcelo CL

更新日期：1982-01-01 00:00:00

abstract：:The internal stratum corneum lipid composition was investigated in relation to depth in vivo in healthy human volunteers by extraction following one, three or five strippings. Automated multiple development high-performance thin-layer chromatography (AMD-HPTLC) and gas chromatography (GC) followed by normalized princi...

journal_title：Archives of dermatological research

authors： Bonté F,Saunois A,Pinguet P,Meybeck A

更新日期：1997-01-01 00:00:00

abstract：:Permeation enhancers are defined as substances that are capable of promoting penetration of drugs into skin and transdermal therapeutic systems offers a more reliable mean of administering drug through the skin. Skin is a natural barrier so it is necessary to employ enhancement strategies to improve topical bioavailab...

journal_title：Archives of dermatological research

authors： Patil UK,Saraogi R

更新日期：2014-07-01 00:00:00

abstract：:The mechanism of action of thalidomide in the treatment of patients with Behçet's disease (BD) is poorly understood. There is some evidence to suggest that certain immunological abnormalities are associated with the pathogenesis of BD. A BD-like mouse model induced by herpes simplex virus (HSV) inoculation shows simil...

journal_title：Archives of dermatological research

authors： Lee ES,Kim YA,Kwon HJ,Bang D,Lee S,Sohn S

更新日期：2004-09-01 00:00:00

abstract：:Epstein-Barr virus (EBV) can infect epithelial cells as well as B lymphocytes. Infection of the male and female genital tracts has recently been demonstrated, and it has been suggested that the virus may be sexually transmissible. In our study we investigated whether EBV can be found in the anal region of sexually act...

journal_title：Archives of dermatological research

authors： Näher H,Lenhard B,Wilms J,Nickel P

更新日期：1995-01-01 00:00:00

abstract：:The deposition of immunoglobulin (Ig) at the dermo-epidermal junction (DEJ) of the skin, frequently observed in autoimmune mouse strains, is similar to that seen in patients with systemic lupus erythematosus (SLE). MRL/Mp-lpr/lpr (MRL/lpr) mice have an autosomal recessive mutant gene, lpr, which produces massive T-cel...

journal_title：Archives of dermatological research

authors： Furukawa F,Ohshio G,Imamura S

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Data on how patients with a history of skin cancer apply sunscreen are lacking. OBJECTIVE:To characterize (1) gender differences in sunscreen application technique (quantity used, anatomic site coverage, and time allocated) and (2) differences in sunscreen application to unaffected skin versus previous skin...

journal_title：Archives of dermatological research

authors： Dang J,Reserva J,Tung-Hahn E,Vasicek B,Krol C,Adams W,Tung R,Alam M

更新日期：2020-12-01 00:00:00

abstract：:Filaggrin, a basic protein of the stratum corneum, was named as such because of its capability to aggregate keratin intermediate filaments in vitro. To investigate its filament-aggregating capability in vivo, we performed immunoelectron microscopy in three autosomal dominant genodermatoses serving as in vivo models of...

journal_title：Archives of dermatological research

authors： Weidenthaler B,Hausser I,Anton-Lamprecht I

更新日期：1993-01-01 00:00:00

abstract：:In order to find, whether 8-MOP has an inhibiting effect on the proliferation of lymphocytes in the dark, we studied in vitro the lymphocyte proliferation by a mitogen (HgCl2) and by an antigen (tuberculin) from 16 psoriatic patients during the first oral PUVA treatment immediately before 8-MOP intake (03.--0.5 mg/kg ...

journal_title：Archives of dermatological research

authors： Lischka G,Decker E

更新日期：1978-05-31 00:00:00

abstract：:Scleroderma is a heterogeneous disease with a complex etiology. As more information is gained about the underlying mechanisms and the improved classifications of scleroderma subtypes, treatments can be better personalized. Improving scleroderma patients' early diagnosis before end organ manifestations occur should imp...

journal_title：Archives of dermatological research

authors： Brady SM,Shapiro L,Mousa SA

更新日期：2016-09-01 00:00:00

abstract：:Stress is a well-known triggering factor along with genetic predisposition on the onset and during the course of psoriasis by altering the cellular constituents of the immune system. In the skin, there is a local hypothalamic-pituitary-adrenal (HPA) axis which is the equivalent of the central HPA axis. Corticotropin-r...

journal_title：Archives of dermatological research

authors： Cemil BC,Canpolat F,Yilmazer D,Eskioğlu F,Alper M

更新日期：2012-03-01 00:00:00

abstract：:Organ size regulation is a highly coordinated process involving complex mechanisms. Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif, also known as WWTR1 (TAZ) have recently been linked to organ size determination and cell proliferation. Pilomatrixoma (PM) is a benign tumor of the a...

journal_title：Archives of dermatological research

authors： Cappellesso R,Bellan A,Saraggi D,Salmaso R,Ventura L,Fassina A

更新日期：2015-05-01 00:00:00

abstract：:Recently, medium-dose UVA1 phototherapy (50 J/cm2) has been introduced as an effective treatment for severe atopic dermatitis (AD). In order to further elucidate the mechanisms by which medium-dose UVA1 irradiation leads to an improvement in skin status in patients with AD, biopsy specimens from ten patients before an...

journal_title：Archives of dermatological research

authors： Breuckmann F,Pieck C,Kreuter A,Bacharach-Buhles M,Mannherz HG,Altmeyer P,von Kobyletzki G

更新日期：2001-04-01 00:00:00

abstract：:An animal experiment is presented in which two groups of pigmented hairless mice were exposed daily to suberythemal doses of UVA to study tumourigenesis. The aim of the study was to estimate the carcinogenic risks of tanning by UVA. The pigmented hairless mice, Skh-hr2, were separated by selective breeding into two gr...

journal_title：Archives of dermatological research

authors： van Weelden H,van der Putte SC,Toonstra J,van der Leun JC

更新日期：1990-01-01 00:00:00

abstract：:Nephrogenic systemic fibrosis (NSF) is a disease characterized by fibrosis of the systemic organs in patients with renal failure. Following the findings of recent epidemiological studies and the finding of gadolinium (Gd) in the skin tissue of NSF patients, it is now definitely known that the use of Gd contrast agents...

journal_title：Archives of dermatological research

authors： Ozawa Y,Hayashi S,Hamasaki Y,Hatamochi A

更新日期：2016-12-01 00:00:00

abstract：:Ultraviolet radiation is the major environmental insult to the skin and stimulates the synthesis of melanin in melanocytes, which then distribute it to the neighboring keratinocytes where it confers photo-protection. Skin color results from the paracrine interaction between these two cell types. Recent studies suggest...

journal_title：Archives of dermatological research

authors： Magina S,Esteves-Pinto C,Moura E,Serrão MP,Moura D,Petrosino S,Di Marzo V,Vieira-Coelho MA

更新日期：2011-04-01 00:00:00

abstract：:A significant difference between keloids and hypertrophic scars could be demonstrated by means of acid elution of lymphoid blood cells and immunofluorescence studies. A total of 20 patients (13 patients with keloids and seven with hypertrophic scars) were investigated. All the 13 patients with keloids revealed in the ...

journal_title：Archives of dermatological research

authors： Janssen de Limpens AM,Cormane RH

更新日期：1982-01-01 00:00:00

abstract：:Keloid is a complex condition with environmental and genetic risk-contributing factors. Two candidate genes, TGFβ1 and SMAD4, located in the same signaling pathway are highly expressed in the keloid fibroblast cells. In a case-control design, TGFβ1 haplotypes showed association with the risk of keloid in the present s...

journal_title：Archives of dermatological research

authors： Emami A,Halim AS,Salahshourifar I,Yussof SJ,Khoo TL,Kannan TP

更新日期：2012-09-01 00:00:00

abstract：:Studies aimed at understanding the pathology, genetics, and therapeutic response of vitiligo rely on asking a single question about 'physician-diagnosed' vitiligo on surveys to identify subjects for research. However, this type of self-reporting is not sufficient. Our objective was to determine if the patient-administ...

journal_title：Archives of dermatological research

authors： Sheth VM,Gunasekera NS,Silwal S,Qureshi AA

更新日期：2015-01-01 00:00:00