Abstract:
:As congenital nevocytic nevi have an increased risk of malignant degeneration, nevus-cell involvement in blood vessels and lymphatics is of particular interest. The present histological and ultrastructural studies revealed nevus-cell nests in the walls of venules in 1 out of 11 patients with medium-sized nevi, and in subcutaneous veins in 3 out of 8 patients with garment nevi. In all cases, the nests histologically consisted of benign-appearing subendothelial B-type cells. Ultrastructurally, the features of these nevocytes essentially corresponded to those of nevocytes in the surrounding area. In 1 patient with a garment nevus, in whom affected vessels of the lumbar area as well as of the neck were examined, the nevus-cell nests were exclusively situated between the endothelium and its basal lamina. These nevocytes appeared to be more electron dense, but had no unequivocally atypical features. In the region of these nests, the endothelium was often discontinuous; thus, the nevus-cells were in direct contact with the lumen. Some of these cells exhibited slight degenerative changes. The lymphatics were affected in 6 of the 18 cases of garment nevi and in 2 of the 11 cases of medium-sized nevi. The morphological findings were comparable to those for blood vessels. It is concluded that, in garment nevi, morphologically benign nevocytes may be carried off hematogenously as well as lymphogenously.
journal_name
Arch Dermatol Resjournal_title
Archives of dermatological researchauthors
Schneider BV,Maie Odoi
10.1007/BF00412496subject
Has Abstractpub_date
1985-01-01 00:00:00pages
49-56issue
1eissn
0340-3696issn
1432-069Xjournal_volume
278pub_type
杂志文章abstract::Although chemokines are critical elements for the selective attraction and activation of various leukocyte subsets in the inflammatory process, there are few findings concerning T helper (Th) 1 or Th2 chemokines in autoimmune blistering disease (ABD). To determine whether serum levels of chemokines that are preferenti...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-006-0661-5
更新日期:2006-06-01 00:00:00
abstract::The present study aimed to observe the therapeutic effect of combined mizolastine and proteoglycan in chronic urticaria. The patients were randomly divided into the treatment group (n = 56) and the control group (n = 44). The treatment group was medicated with calcium gluconate (10 mg/ time, 1 time/day), vitamin D3 (i...
journal_title:Archives of dermatological research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00403-019-01967-0
更新日期:2019-12-01 00:00:00
abstract::Bradykinin has long been postulated to have a major role in physiologic human pain production. We have developed a method to systematically quantify the algogenic response to bradykinin in human skin by the direct application of bradykinin to suction blister bases. After determination of the pain threshold to bradykin...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00371917
更新日期:1992-01-01 00:00:00
abstract::Linoleic acid is required for the formation and maintenance of the epidermal barrier, but most of the current in vitro keratinocyte culture systems are linoleic acid-deficient. The aim of the present study was to examine the efficiency of linoleic acid uptake in human keratinocyte cultures grown under submerged and ai...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050430
更新日期:1999-07-01 00:00:00
abstract::Hydroperoxides of d-limonene were shown to be potent contact allergens when studied in guinea-pigs. Limonene-2-hydroperoxide (2-hydroperoxy-p-mentha-6,8-diene, a mixture of trans and cis isomers) was synthesized for the first time. The ratio between the trans and cis forms was 3:1. These two hydroperoxides were identi...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00370734
更新日期:1994-01-01 00:00:00
abstract::A number of studies have demonstrated an increased frequency of allergen-specific T cells producing increased amounts of interleukin-4 (IL-4) and IL-5, but little interferon-y in both the peripheral blood and skin lesions of patients with atopic dermatitis (AD). In this study, to further clarify the characteristics of...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050359
更新日期:1998-11-01 00:00:00
abstract::In order to find, whether 8-MOP has an inhibiting effect on the proliferation of lymphocytes in the dark, we studied in vitro the lymphocyte proliferation by a mitogen (HgCl2) and by an antigen (tuberculin) from 16 psoriatic patients during the first oral PUVA treatment immediately before 8-MOP intake (03.--0.5 mg/kg ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00455295
更新日期:1978-05-31 00:00:00
abstract::Recently, we reported that UVB-activated indole-3-acetic acid (IAA) induces the apoptosis of G361 human melanoma cells. In the present study, we used IAA and visible light combinations to treat B16F10 melanoma-implanted nude mice using an experimental intense pulsed light (IPL) therapy model. We first investigated whe...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-009-0938-6
更新日期:2009-04-01 00:00:00
abstract::The established mouse epidermis-derived cell line HEL/30 was incubated in the presence of 3H arachidonic acid (AA) for 1 h. After medium removal, cells were reincubated with fresh medium in the presence or absence of the calcium ionophore A23187 and tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate (TPA). The AA me...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00429984
更新日期:1988-01-01 00:00:00
abstract::The effects of acidic and basic fibroblast growth factors (aFGF and bFGF, respectively) on proliferation and differentiation of cultured hair apparatus cells were examined using bovine pituitary extract (BPE)-free media. The importance of FGFs as growth factors in BPE was also examined. Both FGFs and BPE stimulated ce...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00371577
更新日期:1994-01-01 00:00:00
abstract::Exposure to a dry environment leads to depletion of water from the peripheral stratum corneum layers in a process dependent on the relative humidity (RH) and the intrinsic properties of the tissue. We hypothesized that by modulating the water content of the stratum corneum in the surface layers, RH effects the rate of...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030100257
更新日期:2001-09-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-014-1530-2
更新日期:2015-05-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-004-0495-y
更新日期:2004-09-01 00:00:00
abstract::Primary hyperhidrosis is a condition characterized by excessive sweating. The estimated prevalence is between 0.6 and 4.4%, and it can have economic, psychological, and social consequences for affected individuals. Family and genetic studies have suggested a genetic component in the inheritance of the disease. In this...
journal_title:Archives of dermatological research
pub_type: 杂志文章,评审
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更新日期:2019-12-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050419
更新日期:1999-06-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章,meta分析
doi:10.1007/s00403-017-1736-1
更新日期:2017-07-01 00:00:00
abstract::In skin inflammation, vascular endothelial growth factor (VEGF) and CXCL-8/IL-8 play an important role and are produced by activated keratinocytes. Extracts from Ginkgo biloba leaves (GBE), widely used in phytotherapy, have been reported to exert antioxidant and anti-inflammatory properties in the skin. We therefore e...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-009-0979-x
更新日期:2010-04-01 00:00:00
abstract::To investigate the turnover of complete junctional membrane areas ("domain turnover"), psoriatic epidermis, keratoacanthoma, and squamous cell carcinoma were studied with an electron microscope and compared with the normal epidermis. Three types of domain turnover of junctions were observed. First, the uptake of intac...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00510363
更新日期:1982-01-01 00:00:00
abstract::Epidermolytic hyperkeratosis (EH) is a genetic disorder of keratins associated with epidermal differentiation. Affected individuals carry gene mutations for conserved sequences of keratins K1 or K10. The structural alterations of tonofilaments in EH seem to be a direct consequence of the keratin gene mutations. EH epi...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF01105793
更新日期:1995-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00373433
更新日期:1995-01-01 00:00:00
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journal_title:Archives of dermatological research
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-006-0664-2
更新日期:2006-06-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00371599
更新日期:1993-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00371642
更新日期:1990-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00372006
更新日期:1993-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00414112
更新日期:1985-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00372703
更新日期:1992-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00404286
更新日期:1980-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00424270
更新日期:1989-01-01 00:00:00
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journal_title:Archives of dermatological research
pub_type: 杂志文章,评审
doi:10.1007/s00403-016-1635-x
更新日期:2016-05-01 00:00:00