Hyaluronan minimizes effects of UV irradiation on human keratinocytes.

abstract：:Up to now, bicomponent keratohyalin has only been described for rat epithelium and human intraepidermal sweat ducts and fetal nail organ cells. In normal human interductal epidermis, the keratohyalin appears homogeneous, osmiophilic and stellate in shape. Under pathological conditions, bicomponent keratohyalin has bee...

journal_title：Archives of dermatological research

authors： Kastl I,Anton-Lamprecht I

更新日期：1990-01-01 00:00:00

abstract：:Primary hyperhidrosis is a condition characterized by excessive sweating. The estimated prevalence is between 0.6 and 4.4%, and it can have economic, psychological, and social consequences for affected individuals. Family and genetic studies have suggested a genetic component in the inheritance of the disease. In this...

journal_title：Archives of dermatological research

authors： Henning MA,Pedersen OB,Jemec GB

更新日期：2019-12-01 00:00:00

abstract：:Programmed cell death protein-1 (PD-1) is primarily recognized as an inhibitory receptor involved in the regulation of immunological tolerance. However, recent studies have indicated that PD-1/PD-L1 signaling could also regulate the functions of nonimmune cells and may be involved in regulating hair biology. In this s...

journal_title：Archives of dermatological research

authors： Zhou L,Wen L,Sheng Y,Lu J,Hu R,Wang X,Lu Z,Yang Q

更新日期：2021-01-05 00:00:00

abstract：:This study was designed to investigate the proliferative activity of the buccal mucosa in healthy adult persons with regard to individual age. Punch biopsy specimens were taken from the buccal mucosa of 19 individuals (10 females, 9 males) ranging in age from 24 to 80 years, and were then examined autoradiographically...

journal_title：Archives of dermatological research

authors： Maidhof R,Hornstein OP

更新日期：1979-06-25 00:00:00

abstract：:Costimulation of anti-CD3-triggered proliferative T-cell responses by type I and type IV collagen and fibronectin was studied in 25 patients with psoriasis and 12 healthy subjects. The stimulation index of anti-CD3-mediated responses in the presence of type I collagen was about half that in the controls. Although the ...

journal_title：Archives of dermatological research

authors： Glinski W,Gorski A,Glinska-Ferenz M,Majewski S,Stepien-Sopniewska B

更新日期：1995-01-01 00:00:00

abstract：:The goal of this study is to investigate commercially available cosmetics (foundations, skin care creams) which also claim to include a sun protection factor (SPF). Are these products, which are not considered sunscreen products, helpful or could they be harmful? Using an in vitro method, we tested the effectiveness o...

journal_title：Archives of dermatological research

authors： Séhédic D,Hardy-Boismartel A,Couteau C,Coiffard LJ

更新日期：2009-09-01 00:00:00

abstract：:It has been reported that artificial restoration of barrier function by a water vapor-impermeable membrane after tape stripping induces barrier abrogation in hairless mice, impeding rather than enhancing barrier recovery. To address this issue, we examined the morphologic changes in the epidermis after tape stripping ...

journal_title：Archives of dermatological research

authors： Jiang S,Koo SW,Lee SH

更新日期：1998-03-01 00:00:00

abstract：:Serotonin is a monoamine acting as a neuromediator in the central and peripheral nervous system. Recently, serotonin has also been shown to influence T- and B-cell function. The serotonin transporter is central in the regulation of the serotonergic system and widely expressed on cells of the immune system. A functiona...

journal_title：Archives of dermatological research

authors： Mössner R,Stiens G,König IR,Schmidt D,Platzer A,Krüger U,Reich K

更新日期：2009-07-01 00:00:00

abstract：:Patients with atopic dermatitis (AD) often present with dry skin, and the reduced secretion of sebum may be responsible for the impaired skin barrier function. A sebum check film enables the patient to self-evaluate the skin sebum content. This study compared the sebum check film with a sebumeter. The skin sebum conte...

journal_title：Archives of dermatological research

authors： Furuichi M,Makino T,Matsunaga K,Hamade E,Yokoi H,Shimizu T

更新日期：2010-11-01 00:00:00

abstract：:Ultraviolet radiation is the major environmental insult to the skin and stimulates the synthesis of melanin in melanocytes, which then distribute it to the neighboring keratinocytes where it confers photo-protection. Skin color results from the paracrine interaction between these two cell types. Recent studies suggest...

journal_title：Archives of dermatological research

authors： Magina S,Esteves-Pinto C,Moura E,Serrão MP,Moura D,Petrosino S,Di Marzo V,Vieira-Coelho MA

更新日期：2011-04-01 00:00:00

abstract：:Oxidative stress may play a pivotal role in the pathogenesis of psoriasis, an inflammatory/hyperproliferative skin disease characterized by the cutaneous accumulation of neutrophils releasing reactive oxygen species, as revealed in a number of studies. This study was performed to demonstrate the presence of oxidative ...

journal_title：Archives of dermatological research

authors： Yazici C,Köse K,Utaş S,Tanrikulu E,Taşlidere N

更新日期：2016-04-01 00:00:00

abstract：:Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects the patients' quality of life greatly often from a very young age. Its worldwide incidence in children and adults varies, but it is usually among the first ten causes of dermatological consultation worldwide. There is a wide variety of treatmen...

journal_title：Archives of dermatological research

authors： de María Díaz Granados L,Quijano MA,Ramírez PA,Aguirre N,Sanclemente G

更新日期：2018-01-01 00:00:00

abstract：:In a previous study, impedance measurements and phoreographic response were shown to quantify significant differences between involved and non-involved skin in psoriasis. The same techniques were used to objectivate the evolution on skin condition on patients treated with dioxyanthranol, difluprednate, and photochemot...

journal_title：Archives of dermatological research

authors： Cambrai M,Clar EJ,Grosshans E,Altermatt C

更新日期：1979-03-31 00:00:00

abstract：:Scleroderma is a heterogeneous disease with a complex etiology. As more information is gained about the underlying mechanisms and the improved classifications of scleroderma subtypes, treatments can be better personalized. Improving scleroderma patients' early diagnosis before end organ manifestations occur should imp...

journal_title：Archives of dermatological research

authors： Brady SM,Shapiro L,Mousa SA

更新日期：2016-09-01 00:00:00

abstract：:Hand warts were studied in 160 butchers. Clinical and histological studies were performed in 190 warts and virological studies in 165 warts from 104 butchers. Since we found almost perfect correlation between the histological pattern and the type of infecting virus, it was possible to evaluate the virus types in a fur...

journal_title：Archives of dermatological research

authors： Jablońska S,Obalek S,Favre M,Golebiowska A,Croissant O,Orth G

更新日期：1987-01-01 00:00:00

abstract：:Cutaneous adverse drug reactions (ADRs) are common. However, no prospective study assessing cutaneous ADRs is available for Chinese populations. This study aimed to assess the incidence, manifestations, causative drugs, and other factors related to cutaneous ADRs. A total of 22,866 inpatients were surveyed prospective...

journal_title：Archives of dermatological research

authors： Tian XY,Liu B,Shi H,Zhao ZR,Zhou XP,Zhang T,Sun QN,Zuo YG

更新日期：2015-11-01 00:00:00

abstract：:Dopamine causes reflex erythema, central blanching, and piloerection depending on the dose and the type of application wheal reaction. Intracutaneous application shows from 1.5 gamma/0.1 ml wheal formation, erythema, piloerection, and blanching combined with increased heat radiation from the skin surface (AGA thermovi...

journal_title：Archives of dermatological research

authors： Stüttgen G,Dreesen R

更新日期：1979-08-01 00:00:00

abstract：:A procedure measuring the ornithine decarboxylase (ODC) activity and polyamine formation of intact neonatal mouse epidermal cells in culture has been developed and tested. Basal cells prepared from neonatal mouse epidermis were plated on round 15-mm Lux coverslips, placed in Costar 24 well culture clusters and grown a...

journal_title：Archives of dermatological research

authors： Roseeuw DI,Duell EA,Marcelo CL

更新日期：1982-01-01 00:00:00

abstract：:Using the sebum-absorbent tape technique, we have disclosed five different patterns of follicular sebum excretion rate (SER). These are the infantile, pubertal, acne, adult and aging patterns, distinguished by different densities of active sebaceous follicles, by distinct levels of follicular SER and by the relative s...

journal_title：Archives of dermatological research

authors： Piérard GE,Piérard-Franchimont C,Lê T,Lapière C

更新日期：1987-01-01 00:00:00

abstract：:This study was designed to investigate the effects of griseofulvin, 5-fluorocytosine (5-FC), and amphotericin B on pancreatic and gastric secretion after the administration of a single large dose, or repeated small doses for 3 weeks, in male albino rats. The exocrine functions of the main digestive glands were only sl...

journal_title：Archives of dermatological research

authors： Park YK,Lee S,Kim WJ,Hong SS

更新日期：1979-10-01 00:00:00

abstract：:Previous studies have demonstrated that permeability barrier disruption by acetone treatment significantly enhances skin permeability to both hydrophilic and amphipathic compounds, but not to highly lipophilic compounds. The purpose of the present study was to investigate the dependence of permeability on molecular we...

journal_title：Archives of dermatological research

authors： Tsai JC,Hung PL,Sheu HM

更新日期：2001-06-01 00:00:00

abstract：:Dimethylfumarate (DMF), the essential ingredient of the drug product Fumaderm®, is used to treat psoriasis with a recognized favorable long-term safety profile. Interestingly, the mode of action and the pharmacokinetics of DMF in psoriasis or multiple sclerosis are not fully explored. It is known that DMF as an α,β-un...

journal_title：Archives of dermatological research

authors： Dibbert S,Clement B,Skak-Nielsen T,Mrowietz U,Rostami-Yazdi M

更新日期：2013-07-01 00:00:00

abstract：:A novel point mutation in a patient with vascular type Ehlers-Danlos syndrome is herein reported. The patient experienced pneumothorax and multiple arterial troubles during the past 10 years. The patient's hand skin was atrophic, and a paper-like atrophic scar was seen. The collagen microfibrils from the patient's ski...

journal_title：Archives of dermatological research

authors： Okamoto O,Ando T,Watanabe A,Sato F,Mimata H,Shimada T,Fujiwara S

更新日期：2008-10-01 00:00:00

abstract：:Tympanic (Tty), esophageal (Tes), forehead, and hand skin temperatures, as well as the forehead evaporation rate were recorded in six men (four suffering from rosacea and two healthy controls) before, during, and after 1 h of warm bath (38 degrees-39 degrees C). During the last 30 min of the bath, the subject's face w...

journal_title：Archives of dermatological research

authors： Brinnel H,Friedel J,Caputa M,Cabanac M,Grosshans E

更新日期：1989-01-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) and activins are phylogenetically conserved proteins, belonging to the transforming growth factor-β superfamily, that signal through the phosphorylation of receptor-regulated Smad proteins, activating different cell responses. They are involved in various steps of skin morphogenesis ...

journal_title：Archives of dermatological research

authors： Moura J,da Silva L,Cruz MT,Carvalho E

更新日期：2013-09-01 00:00:00

abstract：:The aim of this study was to investigate the effects of Cervi cornus Colla (CCC) in the reconstruction of skin equivalent (SE). H&E staining showed that SE containing hyaluronic acid (HA) or HA and CCC had a thicker epidermis than the control SE. Immunohistochemical staining showed that p63 was mainly present at the b...

journal_title：Archives of dermatological research

authors： Kim J,Jeong HS,Li H,Baek KJ,Kwon NS,Yun HY,Choi HR,Park KC,Kim DS

更新日期：2013-01-01 00:00:00

abstract：:Psoriasis is now recognized as an immune-mediated inflammatory dermatosis with increased risk for metabolic syndrome, its individual components, and cardiovascular disease. We quantitatively estimated malondialdehyde (MDA), lipoprotein-a (LP-a), lipoprotein ratios, comprehensive lipid tetrad index (CLTI), and atheroge...

journal_title：Archives of dermatological research

authors： Wadhwa D,Mahajan VK,Mehta KS,Chauhan PS,Yadav RS,Bhushan S,Sharma V,Sharma A,Sharma A,Chauhan S

更新日期：2019-05-01 00:00:00

abstract：:1. Suction blisters on the skin of rats, obtained with a negative pressure of 150 mm Hg, show a close similarity to human suction blisters, based on histological, electrolyte and protein findings. 2. Pharmacokinetic experiments with inulin and antipyrine have proved that the movement of these low protein binding drugs...

journal_title：Archives of dermatological research

authors： Herfst MJ,van Rees H

更新日期：1978-12-01 00:00:00

abstract：:The mechanistic target of rapamycin (mTOR) is involved in the regulation of cellular growth, proliferation, lipid synthesis, and protein translation. The mTOR pathway involves two complexes: the mechanistic target of rapamycin complex 1 (mTORC1) and the mechanistic target of rapamycin complex 2 (mTORC2). Both mTOR com...

journal_title：Archives of dermatological research

authors： Leo MS,Sivamani RK

更新日期：2014-12-01 00:00:00

abstract：:Using immunoblot and immunofluorescence analysis, we demonstrated the presence and localization of an immunoreactive form of erythrocyte ankyrin in human epidermal keratinocytes. Immunoblot analysis revealed that both human epidermis and cultured epidermal keratinocytes contained ankyrin-like proteins of molecular mas...

journal_title：Archives of dermatological research

authors： Shimizu T,Takakuwa Y,Koizumi H,Ishibashi T,Ohkawara A

更新日期：1996-01-01 00:00:00