Abstract：
:Dopamine causes reflex erythema, central blanching, and piloerection depending on the dose and the type of application wheal reaction. Intracutaneous application shows from 1.5 gamma/0.1 ml wheal formation, erythema, piloerection, and blanching combined with increased heat radiation from the skin surface (AGA thermovision). Epicutaneous application from 500 ml (occlusive patch test) following horny layer stripping, causes marked blanching with weak piloerection. Iontophoretic application of dopamine 1/1,000 (60 s, 0.5 mA) causes only blanching and weak surrounding erythema; application of dopamine 1/100 additionally causes piloerection. This application shows no changing of infrared radiation. Iontophoretic application of dopamine 1/100 or 50 gamma/0.1 ml i.c. in a blanched area after locally applied corticosteroids (McKenzie test) shows diminution of infrared radiation proved by AGA thermovision thermography. Antihistaminics, applied externally, decrease reddening, wheal development as well as blanching by dopamine. Guanethedine (1% in eucerin) increases the blanching phenomenon (false transmitter effect of dopamine). Phentolamine 1% in W/O emulsion is without effect on dopamine reaction. Caffeine ointment (4%) reduces erythema and accentuates the degree of blanching. Oral haloperidol has no influence on the dopamine skin reaction, but increases the blanching in areas of antihistamine treatment. Skin veins and varices show marked vasoconstriction within 10 min after iontophoretic (1 : 100, 3.5 mA, 60 s) or i.c. application (50 gamma/0.2 ml).
journal_name
Arch Dermatol Resjournal_title
Archives of dermatological researchauthors
Stüttgen G,Dreesen Rdoi
10.1007/BF00412863subject
Has Abstractpub_date
1979-08-01 00:00:00pages
59-73issue
1eissn
0340-3696issn
1432-069Xjournal_volume
266pub_type
杂志文章abstract：:The use of underarm cosmetics is common practice in the Western society to obtain better body odor and/or to prevent excessive sweating. A survey indicated that 95 % of the young adult Belgians generally use an underarm deodorant or antiperspirant. The effect of deodorants and antiperspirants on the axillary bacterial...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-014-1487-1
更新日期：2014-10-01 00:00:00
abstract：:Psoriasis is now recognized as an immune-mediated inflammatory dermatosis with increased risk for metabolic syndrome, its individual components, and cardiovascular disease. We quantitatively estimated malondialdehyde (MDA), lipoprotein-a (LP-a), lipoprotein ratios, comprehensive lipid tetrad index (CLTI), and atheroge...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-019-01896-y
更新日期：2019-05-01 00:00:00
abstract：:The hair cycling pattern differs between humans and mice: for the former it is mosaic, while the latter show a wave pattern. We focused on the presence or absence of synchronization of the hair cycle based on the distribution of Merkel cells. The three-dimensional distribution and number of Merkel cells in the skin at...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s004030050474
更新日期：2000-04-01 00:00:00
abstract：:Studies aimed at understanding the pathology, genetics, and therapeutic response of vitiligo rely on asking a single question about 'physician-diagnosed' vitiligo on surveys to identify subjects for research. However, this type of self-reporting is not sufficient. Our objective was to determine if the patient-administ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-014-1515-1
更新日期：2015-01-01 00:00:00
abstract：:Linoleic acid is required for the formation and maintenance of the epidermal barrier, but most of the current in vitro keratinocyte culture systems are linoleic acid-deficient. The aim of the present study was to examine the efficiency of linoleic acid uptake in human keratinocyte cultures grown under submerged and ai...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s004030050430
更新日期：1999-07-01 00:00:00
abstract：:Painting of 3,3',4',5-tetrachlorosalicylanilide (TCSA) plus ultraviolet A (UVA) irradiation to the same site induces contact photosensitivity (CPS), but at the same time results in death of the photohapten-modified cells. Using an in vitro immune lymph node cell (LNC) proliferation system, we investigated the mechanis...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00372063
更新日期：1991-01-01 00:00:00
abstract：:Mitochondrial DNA (mtDNA) mutations have recently been proposed as important contributors to ageing and degenerative diseases. In this study, we applied the polymerase chain reaction technique to detect 4.977 bp-deleted mtDNA, the most common and abundant deletion of mtDNA, in normal human skin. None of the skin speci...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00371798
更新日期：1994-01-01 00:00:00
abstract：:Numerous chemicals to which humans are exposed either therapeutically or as a result of living in an industrial environment constitute a potential threat as carcinogens, mutagens, and/or tumor promoters and cocarcinogens. Anthralin, and antipsoriatic agent, acts as a tumor promoter for Balb/c-3T3 mouse embryo cell cul...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00429985
更新日期：1988-01-01 00:00:00
abstract：:Eleven dysplastic melanocytic naevi with various degrees of dysplasia, as judged by light microscopy, were studied by transmission electron microscopy, and their intra-epidermal melanocytes compared with those of five superficial spreading melanomas and seven common benign naevocellular naevi. Intra-epidermal melanocy...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00372084
更新日期：1990-01-01 00:00:00
abstract：:Certain HPV types have been linked to the genesis and development of premalignant and malignant skin diseases. There have been several contradictory reports on the role of HPV infections in the development of keratoacanthomas (KAs). To further study the involvement of HPVs in the aetiology of KAs, we investigated para...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF02505821
更新日期：1996-03-01 00:00:00
abstract：:This study was designed in order to prove on a large-scale basis the efficacy of oral photochemotherapy (PUVA) in the prevention of polymorphous light eruption (PLE), to work out indication criteria for PUVA treatment of this disease, and to establish a simple method based on anamnestic data to differentiate UVA from ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00417337
更新日期：1983-01-01 00:00:00
abstract：:The aim of the present study was to investigate the influence of three different retinoids, isotretinoin, etretinate and acitretin, on the mitogenic response of peripheral blood mononuclear cells (PBMCs) to PHA and PMA in vitro. All three retinoids at high concentrations (10(-4)M) significantly inhibited the mitogenic...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s004030050291
更新日期：1998-04-01 00:00:00
abstract：:The exposure of naked unprotected skin to solar radiation may result in numerous acute and chronic undesirable effects. Evidence suggests that silymarin, a standardized extract from Silybum marianum (L.) Gaertn. seeds, and its major component silybin suppress UVB-induced skin damage. Here, we aimed to investigate the ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-019-01928-7
更新日期：2019-08-01 00:00:00
abstract：:Splenopentin (SP-5: Arg-Lys-Glu-Val-Tyr), a pentapeptide corresponding to the residues 32-36 of the splenic hormone splenin, increases dose-dependently the number of bone marrow colonies (M and GM colonies). Therefore, we tested the stimulatory effect of SP-5 on the recruitment of epidermal Langerhans cells in skin de...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00412738
更新日期：1990-01-01 00:00:00
abstract：:Treatment of murine skin grafts in vitro with 8-methoxypsoralen and longwave ultraviolet radiation prolonged their subsequent survival on allogeneic recipients, but not in cases where the recipients had been presensitized by a former skin graft of the same donor strain. In contrast to normal skin, grafts pretreated wi...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00511060
更新日期：1984-01-01 00:00:00
abstract：:Keloid is a fibrotic disease characterized by abnormal accumulation of extracellular matrix (ECM) in the dermis. It is a late spreading skin overgrowth and may be considered a plastic surgeon's nightmare. In nature, curcuminoid is composed of curcumin, demethoxycurcumin (DMC) and bisdemethoxycurcumin (bDMC). Curcumino...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-010-1075-y
更新日期：2010-12-01 00:00:00
abstract：:Hidradenitis suppurativa (HS) is a chronic inflammatory disease associated with insulin resistance (IR), metabolic syndrome and increased cardiovascular risk. Adipokines are biologically active, pleotropic molecules which have been involved in the development of IR and in the pathogenesis of several chronic inflammato...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-019-02018-4
更新日期：2020-10-01 00:00:00
abstract：:Artificial light at night (LAN) is a pervasive phenomenon in today's society, and the detrimental consequences of LAN exposure are becoming apparent. LAN is associated with the increased incidence of metabolic disorders, cancers, mood alterations, and immune dysfunction in mammals. Consequently, we examined the effect...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-019-01935-8
更新日期：2019-09-01 00:00:00
abstract：:The topical application of a mixture of sugar and povidone--iodine (PI) has been reported to accelerate the healing of cutaneous wounds and ulcers by promoting re-epithelialization and granulation tissue formation as well as having an anti-microbial effect. To clarify the mechanisms accounting for the efficacy of a 70...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-006-0683-z
更新日期：2006-09-01 00:00:00
abstract：:As congenital nevocytic nevi have an increased risk of malignant degeneration, nevus-cell involvement in blood vessels and lymphatics is of particular interest. The present histological and ultrastructural studies revealed nevus-cell nests in the walls of venules in 1 out of 11 patients with medium-sized nevi, and in ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00412496
更新日期：1985-01-01 00:00:00
abstract：:The case of a 44-year-old man with a primary cutaneous large B-cell non-Hodgkin's lymphoma of the scalp is reported. His mother died of gastric lymphoma and his sib brother is in a 20-year remission of T-cell lymphoma. The patient presented with a 16-year history of occipital and parietal alopecia and a recently worse...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-009-0967-1
更新日期：2009-10-01 00:00:00
abstract：:Atopic dermatitis (AD) can be exacerbated by various factors, including emotional stress, scratching and sweating. The aim of the present study was to evaluate the hypothesis that the inflammatory reaction in AD is also neurogenic. For this purpose, the levels of vasoactive intestinal polypeptide were measured radioim...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF01106107
更新日期：1991-01-01 00:00:00
abstract：:Epstein-Barr virus (EBV) can infect epithelial cells as well as B lymphocytes. Infection of the male and female genital tracts has recently been demonstrated, and it has been suggested that the virus may be sexually transmissible. In our study we investigated whether EBV can be found in the anal region of sexually act...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00374084
更新日期：1995-01-01 00:00:00
abstract：:CCN2 plays an important role in the pathogenesis of hypertrophic scars (HTSs). Although CCN2 is involved in many fibroproliferative events, the CCN2 induction signaling pathway in HTSs is yet to be elucidated. Here, we first investigated the effect of the mitogen-activated protein kinases (MAPKs) on CCN2-induced α-smo...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-013-1334-9
更新日期：2013-07-01 00:00:00
abstract：:We report the clinical features of 62 consecutive patients with lichen planus observed in 18 months. The largest number of cases occurred between 50 and 70 years of age. Thirty-four patients had lichen planus only. In the remainder, lichen planus was associated with chronic liver diseases (16 cases), immune-related di...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:In the study described here we investigated the possibility of an association between the aggressiveness of melanoma and multidrug resistance phenotype by analyzing the expression and activity of P-glycoprotein (Pgp) in two genetically related transplantable hamster melanomas--a melanotic (Ma) and an amelanotic (Ab) f...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s004030000146
更新日期：2000-07-01 00:00:00
abstract：:Mouse S91 melanoma cells which grow as a monolayer in culture were studied by transmission and scanning electron microscopy after fixation in situ. The cells were spindle-shaped and tended to grow in dense colonies. Melanosomes at all stages of melanization (stages I-IV) were observed. Other cell organelles reflected ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00431064
更新日期：1989-01-01 00:00:00
abstract：:To investigate the relationship between smoking and primary basal cell carcinoma (BCC), we analyzed data from a 16 year prospective study among randomly selected adults in Nambour, Queensland, Australia. Participants underwent a skin examination in 1992 and took part in an intervention study and follow-up. Information...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-014-1503-5
更新日期：2014-11-01 00:00:00
abstract：:Androgenetic alopecia (AGA) is a dermatological disorder of scalp hair loss characterized by a progressive miniaturization of hair follicles with shortened anagen phase leading to a decreased number of hairs on the scalp. It is a complex polygenic trait prevailing around two-thirds of the male population. Elevated exp...
journal_title：Archives of dermatological research
pub_type： 杂志文章,评审
doi：10.1007/s00403-018-1826-8
更新日期：2018-07-01 00:00:00
abstract：:Propylene glycol (propane-1,2-diol) is the only diol widely used in dermatology. Pentane-1,5-diol is mainly used as a plasticizer in cellulose products and adhesives, in dental composites and in brake fluid compositions and as a preservative for grain. However, pentane-1,5-diol is also an effective solvent, water-bind...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-005-0610-8
更新日期：2005-12-01 00:00:00
