A pilot study of the UVA-photoprotective potential of dehydrosilybin, isosilybin, silychristin, and silydianin on human dermal fibroblasts.

abstract：:Mice homozygous for three different recessive mutations known to cause pleiotropic defects in the immune system and in the skin were used to evaluate the relationship between the classical immune system and dendritic epidermal cell populations. Numbers of Langerhans cells (LCs) and Thy-1+ dendritic cells (Thy-1+DEC) w...

journal_title：Archives of dermatological research

authors： Sprecher E,Becker Y,Kraal G,Hall E,Shultz LD

更新日期：1990-01-01 00:00:00

abstract：:Human epidermal keratinocytes were grown in culture and the uptake of hematoporphyrin derivatives (HPDs) used in photodynamic therapy was estimated. Keratinocytes loaded with HPDs were irradiated with laser light of 632 nm generated by a helium-neon laser and cell toxicity was determined by the trypan blue exclusion t...

journal_title：Archives of dermatological research

authors： Artuc M,Ramshad M,Kappus H

更新日期：1989-01-01 00:00:00

abstract：:Tranilast is used clinically as a drug for hypertrophic scars or keloids. Recently, the roles of keratinocytes in the pathogenesis of those conditions have been noted. Therefore, we first examined the effect of tranilast on the cell growth of normal human keratinocytes. A cell growth assay demonstrated that the cell n...

journal_title：Archives of dermatological research

authors： Kubo M,Zhao Y,Moriguchi T

更新日期：2012-11-01 00:00:00

abstract：:The rhino mouse comedolytic model and the hairless mouse photoaging model are established animal models for screening the in vivo activity of retinoids. However, the expression of the retinoic acid receptors (RARs) and cellular retinoic acid-binding proteins (CRABPs), known to regulate retinoid activity, is not comple...

journal_title：Archives of dermatological research

authors： Beehler BC,Chen S,Tramposch KM

更新日期：1995-01-01 00:00:00

abstract：:The deposition of immunoglobulin (Ig) at the dermo-epidermal junction (DEJ) of the skin, frequently observed in autoimmune mouse strains, is similar to that seen in patients with systemic lupus erythematosus (SLE). MRL/Mp-lpr/lpr (MRL/lpr) mice have an autosomal recessive mutant gene, lpr, which produces massive T-cel...

journal_title：Archives of dermatological research

authors： Furukawa F,Ohshio G,Imamura S

更新日期：1993-01-01 00:00:00

abstract：:CD271, a receptor of nerve growth factor (NGF), affects the biological properties of epidermal stem cells (eSCs) which are essential for skin wound closure. Tropomyosin-receptor kinase A (TrkA), another receptor of NGF, combined with CD271 has been involved with nervous system and skin keratinocytes. However, the exac...

journal_title：Archives of dermatological research

authors： Zhang M,Zhang Y,Ding J,Li X,Zang C,Yin S,Ma J,Wang Y,Cao Y

更新日期：2018-11-01 00:00:00

abstract：:Hand warts were studied in 160 butchers. Clinical and histological studies were performed in 190 warts and virological studies in 165 warts from 104 butchers. Since we found almost perfect correlation between the histological pattern and the type of infecting virus, it was possible to evaluate the virus types in a fur...

journal_title：Archives of dermatological research

authors： Jablońska S,Obalek S,Favre M,Golebiowska A,Croissant O,Orth G

更新日期：1987-01-01 00:00:00

abstract：:Nephrogenic systemic fibrosis (NSF) is a disease characterized by fibrosis of the systemic organs in patients with renal failure. Following the findings of recent epidemiological studies and the finding of gadolinium (Gd) in the skin tissue of NSF patients, it is now definitely known that the use of Gd contrast agents...

journal_title：Archives of dermatological research

authors： Ozawa Y,Hayashi S,Hamasaki Y,Hatamochi A

更新日期：2016-12-01 00:00:00

abstract：:We previously showed that the homeodomain protein HOXC13 is involved in the expression control of the early human hair keratin genes hHa5 and hHa2, which contain specific HOXC13 binding sites in their proximal promoters. Hox specificity is generally thought to be enhanced by the interaction with members of the TALE su...

journal_title：Archives of dermatological research

authors： Jave-Suárez LF,Schweizer J

更新日期：2006-02-01 00:00:00

abstract：:HaCaT keratinocytes differ from normal human epidermal keratinocytes (HEK) by constitutive expression of differentiation markers which are normally suppressed by vitamin A. In search of an explanation for this discrepancy we compared the vitamin A content, the expression of retinoid-binding proteins, and the vitamin A...

journal_title：Archives of dermatological research

authors： Törmä H,Rollman O,Vahlquist A

更新日期：1999-06-01 00:00:00

abstract：:Epidermolytic hyperkeratosis (EH) is a genetic disorder of keratins associated with epidermal differentiation. Affected individuals carry gene mutations for conserved sequences of keratins K1 or K10. The structural alterations of tonofilaments in EH seem to be a direct consequence of the keratin gene mutations. EH epi...

journal_title：Archives of dermatological research

authors： Ishida-Yamamoto A,Iizuka H,Manabe M,O'Guin WM,Hohl D,Kartasova T,Kuroki T,Roop DR,Eady RA

更新日期：1995-01-01 00:00:00

abstract：:Renal allograft recipients were shown to have an increased incidence of warts and skin cancers. We examined 148 patients for evidence of wart virus infections and tested for papillomavirus types, which are known to be associated with human malignancies. Of the 148, 36 (24.3%) patients were afflicted with warts at the ...

journal_title：Archives of dermatological research

authors： Gassenmaier A,Fuchs P,Schell H,Pfister H

更新日期：1986-01-01 00:00:00

abstract：:To investigate the relationship between smoking and primary basal cell carcinoma (BCC), we analyzed data from a 16 year prospective study among randomly selected adults in Nambour, Queensland, Australia. Participants underwent a skin examination in 1992 and took part in an intervention study and follow-up. Information...

journal_title：Archives of dermatological research

authors： Hughes MC,Olsen CM,Williams GM,Green AC

更新日期：2014-11-01 00:00:00

abstract：:Splenopentin (SP-5: Arg-Lys-Glu-Val-Tyr), a pentapeptide corresponding to the residues 32-36 of the splenic hormone splenin, increases dose-dependently the number of bone marrow colonies (M and GM colonies). Therefore, we tested the stimulatory effect of SP-5 on the recruitment of epidermal Langerhans cells in skin de...

journal_title：Archives of dermatological research

authors： Gruner S,Diezel W,Strunk D,Zwirner A,Sönnichsen N,Anhalt GJ

更新日期：1990-01-01 00:00:00

abstract：:Staphylococcus aureus is a common wound-infecting organism which can interact with cells via the extracellular matrix protein fibronectin (FN). The aim of this study was to determine the effect of the FN-binding protein (FnBP) of S. aureus on the behaviour of a human skin keratinocytes cell line (UP). FN-coated plates...

journal_title：Archives of dermatological research

authors： Kintarak S,Nair SP,Speight PM,Whawell SA

更新日期：2004-11-01 00:00:00

abstract：:One of the primary events in the pathogenesis of acne vulgaris is abnormal follicular keratinization. Since oral isotretinoin therapy reduces follicular hyperkeratinization in acne, our study has been designed to determine whether epidermal lipid composition of the epithelium of sebaceous follicles is affected by isot...

journal_title：Archives of dermatological research

authors： Melnik B,Kinner T,Plewig G

更新日期：1988-01-01 00:00:00

abstract：:Mite antigens play important roles in the pathogenesis of atopic dermatitis (AD). We recently developed a novel air cleaner (KC-850U) using charged plasma cluster ions to eliminate a variety of allergens from house environments. The present work demonstrates the ability of KC-850U to decrease the symptoms of AD induce...

journal_title：Archives of dermatological research

authors： Hiramoto K,Orita K,Yamate Y,Sato EF,Okano H,Nishikawa K,Inoue M

更新日期：2011-07-01 00:00:00

abstract：:Using the sebum-absorbent tape technique, we have disclosed five different patterns of follicular sebum excretion rate (SER). These are the infantile, pubertal, acne, adult and aging patterns, distinguished by different densities of active sebaceous follicles, by distinct levels of follicular SER and by the relative s...

journal_title：Archives of dermatological research

authors： Piérard GE,Piérard-Franchimont C,Lê T,Lapière C

更新日期：1987-01-01 00:00:00

abstract：:Lichen planus (LP) is a chronic inflammatory, T cell-mediated autoimmune skin disease. Innate immunity could explain the interplay between environmental triggers and the autoimmune cascade leading to disease development. Toll-like receptors (TLRs) are important components of the innate immune system, with no previous ...

journal_title：Archives of dermatological research

authors： Salem SA,Abu-Zeid RM,Nada OH

更新日期：2013-03-01 00:00:00

abstract：:Pemphigus is a general term for a rare group of autoimmune diseases which result in the formation of blisters on the skin and oral cavity. Although there is no way to prevent autoimmune diseases, some factors may trigger pemphigus initiation in susceptible individuals or be exacerbated in affected patients. Recognitio...

journal_title：Archives of dermatological research

authors： Tavakolpour S

更新日期：2018-03-01 00:00:00

abstract：:Besides its role in small-cell carcinoma of the lung, elevated serum levels of neuron-specific enolase (NSE) have recently been reported to be associated with autoimmune rheumatic disorders such as systemic sclerosis. Serum NSE seems to correlate with disease activity as well as Rodnan skin score. The aim of the study...

journal_title：Archives of dermatological research

authors： Breuckmann F,Appelhans C,Bastian A,Stuecker M,Altmeyer P,Kreuter A

更新日期：2004-09-01 00:00:00

abstract：:Previous studies in mice have shown that dehydroepiandrosterone (DHEA) increases the production of Th1-associated lymphokines, and of interleukin-2 (IL-2) and interferon-gamma (IFN-gamma), by lymphocytes. However, there are no reports concerning the effect of DHEA on the production of Th2-associated lymphokines, IL-4 ...

journal_title：Archives of dermatological research

authors： Tabata N,Tagami H,Terui T

更新日期：1997-06-01 00:00:00

abstract：:The skin is the major site on anaphylaxis, and cutaneous mast cells have an important role in its reactions. The isolation and purification of rat cutaneous mast cells are described here. Rat abdominal skin was digested with collagenase and hyaluronidase, and centrifuged with Percoll. The buoyant density of cutaneous ...

journal_title：Archives of dermatological research

authors： Hachisuka H,Kusuhara M,Higuchi M,Okubo K,Sasai Y

更新日期：1988-01-01 00:00:00

abstract：:Two male patients with longstanding contact sensitivity to chromium were treated with PUVA. One patient, suffering from concomitant photosensitivity, reacted very favorably; his skin lesions cleared and light tolerance increased. This was paralleled by a decrease in the photopatch test reactivity and by the extinction...

journal_title：Archives of dermatological research

authors： Jansén CT,Viander M,Kalimo K,Soppi AM,Soppi E

更新日期：1981-01-01 00:00:00

abstract：:The topical application of a mixture of sugar and povidone--iodine (PI) has been reported to accelerate the healing of cutaneous wounds and ulcers by promoting re-epithelialization and granulation tissue formation as well as having an anti-microbial effect. To clarify the mechanisms accounting for the efficacy of a 70...

journal_title：Archives of dermatological research

authors： Nakao H,Yamazaki M,Tsuboi R,Ogawa H

更新日期：2006-09-01 00:00:00

abstract：:Recently a new thin layer chromatography plate (Whatman LK 6D) became available which is extremely easy to handle and permits highly reproducible qualitative and quantitative analysis. This plate proved to be of great value for the investigation of skin surface lipids. The use of a fatty acid methyl ester as an intern...

journal_title：Archives of dermatological research

authors： Weissmann A

更新日期：1979-07-30 00:00:00

abstract：:The penetration and permeation of the recombinant protein plasminogen activator inhibitor type 2 (PAI-2) in two formulations, one containing a penetration enhancer, into the psoriatic and uninvolved skin of eight patients with plaque-type psoriasis were investigated. Penetration and permeation of PAI-2 were measured b...

journal_title：Archives of dermatological research

authors： Gould AR,Sharp PJ,Smith DR,Stegink AJ,Chase CJ,Kovacs JC,Penglis S,Chatterton BE,Bunn CL

更新日期：2003-11-01 00:00:00

abstract：:Angiosarcoma, a malignant tumor of vascular endothelial cell origin, is a lethal disease for which complete cure is rarely seen. The objective of this study was to determine the efficiency of photodynamic therapy (PDT) as a new treatment for angiosarcoma. PDT (630 nm, 25 J/cm2) using Photofrin for a mouse angiosarcoma...

journal_title：Archives of dermatological research

authors： Jin I,Yuji M,Yoshinori N,Makoto K,Mikio M

更新日期：2008-04-01 00:00:00

abstract：:Medical innovation is crucial to advancing our field, and physicians have the potential to play a leading role due to their daily patient care experiences. The objective of this study was to evaluate the interest in, and barriers to participating in innovation. Two surveys were conducted; the first cross-sectional sur...

journal_title：Archives of dermatological research

authors： Lee KC,Lee I,Okhovat JP,Ko J,Powers JG,Ellis DL,Cheeley J,Garibyan L

更新日期：2020-08-09 00:00:00

abstract：:An ultrastructural study of the skin lesion of a young patient affected by pseudo-Kaposi's sarcoma of the Bluefarb-Stewart type (BSS) is reported. The neoplasm consisted of a proliferation of vascular structures mostly consisting of a solid bud of endothelial cells surrounded by a thinned and polystratified basement m...

journal_title：Archives of dermatological research

authors： Fimiani M,Simoni S,Miracco C,De Santi M,Luzi P,Andreassi L

更新日期：1989-01-01 00:00:00