Abstract：
:The case of a 44-year-old man with a primary cutaneous large B-cell non-Hodgkin's lymphoma of the scalp is reported. His mother died of gastric lymphoma and his sib brother is in a 20-year remission of T-cell lymphoma. The patient presented with a 16-year history of occipital and parietal alopecia and a recently worsening scalp rash. The histopathology and immunohistochemistry performed in April 2006 indicated a bcl-6+, MUM- and bcl-2-, primary cutaneous follicle center B-cell non-Hodgkin's lymphoma, with an aggressive transformation to a diffuse large B-cell lymphoma. Bone marrow biopsy and CT chest, abdomen, and pelvis were negative for systemic lymphoma. The patient had an excellent clinical and histological resolution following 8 cycles of rituximab and CHOP protocol immunochemotherapy, and remains in complete remission until now. The protracted indolent phase of the disease, the familial history of lymphoma, the histological aggressive features and the patient's excellent response to immunochemotherapy all contribute to a very unusual manifestation of this disease.
journal_name
Arch Dermatol Resjournal_title
Archives of dermatological researchauthors
Colovic N,Jurisic V,Terzic T,Atkinson HD,Colovic Mdoi
10.1007/s00403-009-0967-1subject
Has Abstractpub_date
2009-10-01 00:00:00pages
689-92issue
9eissn
0340-3696issn
1432-069Xjournal_volume
301pub_type
杂志文章abstract：:Abnormal dermal deposition of elastic fibers is the earliest and most striking effect of prolonged sun exposure (solar elastosis). The hyperplastic fibers are usually ascribed to ultraviolet (UV) rays. Nonetheless, other portions of the solar spectrum may play contributing roles. Heat, for example, enhances experiment...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00509050
更新日期：1982-01-01 00:00:00
abstract：:Recent evidence indicates that the biologically active metabolite of vitamin D3, 1 alpha,25-dihydroxyvitamin D3 [1 alpha,25(OH)2D3], has an effect on the regulation of the immune response. We investigated whether topical treatment of mice with 1 alpha,25(OH)2D3 influences the contact hypersensitivity (CHS) response to...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00412982
更新日期：1989-01-01 00:00:00
abstract：:The authors report 2 cases of atypical vitiligo in which they observed 1) "cockade-like" lesions resembling those of "trichrome" vitiligo (from the centre to the periphery, achromic area, hypochromic ring, normal or hyperchromic border), 2) numerous linear achromic lesions corresponding to former excoriations (Koebner...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00455391
更新日期：1978-07-28 00:00:00
abstract：:Interleukin-6 (IL-6) is a multifunctional cytokine which has been suggested to function as an autocrine mitogen in psoriatic epidermis. We report here the results of several experiments designed to further examine this hypothesis. Blot hybridization was unable to detect 1.3 kb IL-6 transcripts in RNA extracted from no...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00372034
更新日期：1992-01-01 00:00:00
abstract：:Because of its easy accessibility, the skin is a very attractive target for gene therapy purposes. To study potential clinical applications in a preclinical setting, appropriate animal models are needed. Pig skin is very similar to human skin, and a variety of human diseases that are potentially amenable to gene thera...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-006-0653-5
更新日期：2006-06-01 00:00:00
abstract：:Glycerol, widely used as humectant, is known to protect against irritants and to accelerate recovery of irritated skin. However, most studies were done with topical formulations (i.e. emulsions) containing glycerol in relatively high amounts, preventing drawing conclusions from direct effects. In this study, acute che...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-009-1021-z
更新日期：2010-08-01 00:00:00
abstract：:Botulinum toxin type A (BoNT-A) is an easy and fast treatment for gingival smile (GS). The objective of the study was to compare the reduction of gingival exposure using three different doses of abobotulinumtoxinA (ABO) in patients with different severities of anterior GS, and to assess treatment safety and patients' ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-020-02096-9
更新日期：2020-07-28 00:00:00
abstract：:Congenital atrichia (AUC) is a form of isolated alopecia with an autosomal recessive mode of inheritance. Patients are born with normal hair but this is shed almost completely during the first weeks or months of life and never regrows. In many families the development of papular lesions is noted as an additional pheno...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-007-0747-8
更新日期：2007-06-01 00:00:00
abstract：:About 5% of all cutaneous squamous cell carcinomas (cSCCs) metastasize, which is the principal cause of death by this type of cancer. However, to date there are no reliable biomarkers that categorize those SCC patients that will progress to metastasis. Nuclear active IKKα diminishes Maspin levels in prostate cancer fa...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-015-1579-6
更新日期：2015-10-01 00:00:00
abstract：:In many skin diseases such as Demodex folliculitis, rosacea- or steroid-induced rosacea Demodex mites are present in abundance and are at least partially held responsible for causing these disorders. Although it is known that these diseases respond well to tetracyclines, it is unclear if this is due to the antiinflamm...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-009-0984-0
更新日期：2009-10-01 00:00:00
abstract：:The demonstration of cytokine mRNA expression in epidermal cells by the polymerase chain reaction technique preceded by reverse transcription (RT-PCR) requires linear test conditions (i.e. that the product obtained after amplification reflects the relative amounts of starting material) and high reproducibility, specif...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00370722
更新日期：1994-01-01 00:00:00
abstract：:HLA types were determined in 19 patients and 9 healthy members of 2 Danish families with hereditary angioneurotic edema. The study revealed no connections between hereditary angioneurotic edema and the HLA system. ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00409265
更新日期：1982-01-01 00:00:00
abstract：:Test results are reported of the effect of salicylic acid on the vasoconstrictive effect of flumethasone pivalate. In specific, the depigmentation of the skin (identical with increase in lightness of the skin) following topical application of flumethasone pivalate was investigated with the aid of an improved spectroph...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00417384
更新日期：1981-01-01 00:00:00
abstract：:The expression of IL-8 in psoriasis has been clearly shown with the use of immunocytochemical, RT-PCR and in situ hybridization methods. The presence of its ligand, the IL-8 receptor, has been demonstrated by the RT-PCR technique. We report here a study of the expression of both IL-8 type A and B receptors by immunohi...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s004030050218
更新日期：1997-07-01 00:00:00
abstract：:Using a sensitive and modified solid-phase radioimmunoassay for detecting anti-cardiolipin antibodies, sera of 45 patients with lepromatous leprosy were examined. Nine of the 45 (20%) showed positive levels of anti-cardiolipin antibodies. Inhibition tests revealed that these antibodies significantly cross-reacted with...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00407745
更新日期：1986-01-01 00:00:00
abstract：:Psoriasis, a chronic inflammatory skin disease, is associated with oxidative stress of serum lipoproteins. In psoriatic children we evaluated the activity and levels of myeloperoxidase, the activity of paraoxonase-1 (PON1) and biochemical markers of lipid peroxidation, to investigate wether an unbalance between oxidan...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-019-01976-z
更新日期：2020-01-01 00:00:00
abstract：:In 1901, Hans Vörner observed a family with a diffuse non-transgredient palmoplantar keratoderma of autosomal dominant inheritance. Histopathologically, he found epidermolytic hyperkeratosis as a characteristic sign and diagnostic criterion of this disorder. We performed a follow-up study of the family originally seen...
journal_title：Archives of dermatological research
pub_type： 历史文章,杂志文章
doi：10.1007/s00403-002-0328-9
更新日期：2002-08-01 00:00:00
abstract：:Skin lesions of three patients with inflammatory linear verrucose epidermal naevus (ILVEN) were examined. Histologically, orthokeratosis and parakeratosis were alternately seen in the acanthotic epidermis. By N-(7-dimethylamino-4-methyl-3-coumarinyl)maleimide staining, the horny cells in the parakeratotic epidermis sh...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00371921
更新日期：1991-01-01 00:00:00
abstract：:Metalloproteinase-mediated proteolysis plays an important role during all stages of wound repair. In acute murine wounds, murine collagenase, matrix metalloproteinase (MMP)-9, stromelysin-1, stromelysin-2 and tissue inhibitor of metalloproteinase (TIMP)-1 are strongly induced within 24 h after wounding. At the time of...
journal_title：Archives of dermatological research
pub_type： 杂志文章,评审
doi：10.1007/pl00007450
更新日期：1998-07-01 00:00:00
abstract：:The impact of search strategies on systematic reviews (SR) of atopic dermatitis (AD) is unknown. The purpose of this review was to evaluate search strategies used in SR of AD and their impact on the frequency of manuscripts identified. MEDLINE and EMBASE were searched for SR related to AD. Simulations were performed b...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-020-02165-z
更新日期：2020-11-22 00:00:00
abstract：:The use of microalgae in the skin care market is already established although the scientific rationale for their benefit was not clearly defined. In this work, the biological activities of dermatologic interest of the water extract from the microalga Botryococcus braunii (BBWE) were evaluated by a battery of in vitro ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-012-1250-4
更新日期：2012-11-01 00:00:00
abstract：:Painting of 3,3',4',5-tetrachlorosalicylanilide (TCSA) plus ultraviolet A (UVA) irradiation to the same site induces contact photosensitivity (CPS), but at the same time results in death of the photohapten-modified cells. Using an in vitro immune lymph node cell (LNC) proliferation system, we investigated the mechanis...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00372063
更新日期：1991-01-01 00:00:00
abstract：:Delayed pressure urticaria (DPU) is characterized by deep dermal wheals that appear in response to a local continuous pressure. Although it has been reported to complicate as many as 40% of cases of Caucasian patients with chronic urticaria, no definitive cases of Asian/Japanese patients have been reported in English ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-010-1053-4
更新日期：2010-10-01 00:00:00
abstract：:The mechanism of action of thalidomide in the treatment of patients with Behçet's disease (BD) is poorly understood. There is some evidence to suggest that certain immunological abnormalities are associated with the pathogenesis of BD. A BD-like mouse model induced by herpes simplex virus (HSV) inoculation shows simil...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-004-0498-8
更新日期：2004-09-01 00:00:00
abstract：:Linoleic acid is required for the formation and maintenance of the epidermal barrier, but most of the current in vitro keratinocyte culture systems are linoleic acid-deficient. The aim of the present study was to examine the efficiency of linoleic acid uptake in human keratinocyte cultures grown under submerged and ai...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s004030050430
更新日期：1999-07-01 00:00:00
abstract：:Previous studies in mice have shown that dehydroepiandrosterone (DHEA) increases the production of Th1-associated lymphokines, and of interleukin-2 (IL-2) and interferon-gamma (IFN-gamma), by lymphocytes. However, there are no reports concerning the effect of DHEA on the production of Th2-associated lymphokines, IL-4 ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s004030050213
更新日期：1997-06-01 00:00:00
abstract：:Sixteen malignant melanoma patients with different levels of tumor progression, two patients with melanoma in situ (Clark 10 two bronchogenic carcinoma patients and nine healthy controls were tested by means of the leukocyte adherence inhibition (LAI) test to assess the function of their cellular mediated immunity. Bl...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00403801
更新日期：1980-01-01 00:00:00
abstract：:A 2% commercial solution formulation of 5-fluorouracil (5-FU) was significantly better at delivering 5-FU than either a 1% or 5% solution. Among single component suspension formulations the highest transdermal delivery was obtained from the vehicle in which 5-FU was least soluble, isopropyl myristate (IPM), while chan...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/BF00402624
更新日期：1990-01-01 00:00:00
abstract：:The pathogenicity of Mycobacterium ulcerans (Buruli ulcer) is closely associated with the secretion of exotoxin mycolactone. The cytotoxicity of mycolactone has been linked to its apoptogenic activity. We explored if low mycolactone concentrations, which are not able to induce apoptosis, can influence other essential ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s00403-017-1719-2
更新日期：2017-04-01 00:00:00
abstract：:It has been reported that artificial restoration of barrier function by a water vapor-impermeable membrane after tape stripping induces barrier abrogation in hairless mice, impeding rather than enhancing barrier recovery. To address this issue, we examined the morphologic changes in the epidermis after tape stripping ...
journal_title：Archives of dermatological research
pub_type： 杂志文章
doi：10.1007/s004030050280
更新日期：1998-03-01 00:00:00
