Abstract:
:The authors report 2 cases of atypical vitiligo in which they observed 1) "cockade-like" lesions resembling those of "trichrome" vitiligo (from the centre to the periphery, achromic area, hypochromic ring, normal or hyperchromic border), 2) numerous linear achromic lesions corresponding to former excoriations (Koebner's phenomenon, isomorphic phenomenon). Related affections are discussed with reference to these cases; the trichrome vitiligo described by Lerner and Fitzpatrick, and the primary leukomelanodermas described in black patients by Basset and by Sarrat and Nouhouayi.
journal_name
Arch Dermatol Resjournal_title
Archives of dermatological researchauthors
Dupré A,Christol Bdoi
10.1007/BF00455391subject
Has Abstractpub_date
1978-07-28 00:00:00pages
197-203issue
2eissn
0340-3696issn
1432-069Xjournal_volume
262pub_type
杂志文章abstract::Marie Unna Hereditary Hypotrichosis 1 (MUHH1; OMIM 146550), a rare monogenic condition characterized by the development of sparse, twisted hair or complete hair loss, is the consequence of mutations located in the hairless (HR) gene. We have identified a 68-year-old Hungarian woman affected by alopecia universalis and...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-012-1244-2
更新日期:2012-10-01 00:00:00
abstract::Epstein-Barr virus (EBV) can infect epithelial cells as well as B lymphocytes. Infection of the male and female genital tracts has recently been demonstrated, and it has been suggested that the virus may be sexually transmissible. In our study we investigated whether EBV can be found in the anal region of sexually act...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00374084
更新日期:1995-01-01 00:00:00
abstract::The presence, distribution and cellular localization of tumour necrosis factor-alpha (TNF alpha) were investigated in normal human and murine epidermis using immunohistological and immunoelectron microscopic methods with monoclonal and polyclonal antibodies. The immunostaining revealed an intercellular plasma membrane...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00372709
更新日期:1992-01-01 00:00:00
abstract::We have observed that lipopolysaccharide (LPS) induces pigmentation in melanocytes and in this study have examined whether these responses are mediated by the p38 mitogen-activated protein kinase (MAPK) signaling pathway. LPS appears to stimulate the pigmentation of melanocytes and cultured skin. LPS was found to indu...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-008-0863-0
更新日期:2008-07-01 00:00:00
abstract::Comparative measurements of collagen synthesis as a portion of total protein synthesis were performed with fragments of peripheral neurofibromas, of skin adjacent to the tumors, and of unaffected skin from patients with neurofibromatosis (NF). No significant difference was found among these various samples. Collagen s...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00412930
更新日期:1986-01-01 00:00:00
abstract::The expression of IL-8 in psoriasis has been clearly shown with the use of immunocytochemical, RT-PCR and in situ hybridization methods. The presence of its ligand, the IL-8 receptor, has been demonstrated by the RT-PCR technique. We report here a study of the expression of both IL-8 type A and B receptors by immunohi...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050218
更新日期:1997-07-01 00:00:00
abstract::Ichthyosis Follicularis, Atrichia, and Photophobia (IFAP) is a severe rare genetic disorder caused by mutations in the gene encoding the Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2). Olmsted syndrome is another rare genetic disease with overlapping clinical features caused by mutations in the gene en...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-017-1762-z
更新日期:2017-10-01 00:00:00
abstract::Licochalcone A (LicA), a major phenolic constituent of the licorice species Glycyrrhiza inflata, has recently been reported to have anti-inflammatory as well as anti-microbial effects. These anti-inflammatory properties might be exploited for topical applications of LicA. We conducted prospective randomized vehicle-co...
journal_title:Archives of dermatological research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00403-006-0654-4
更新日期:2006-06-01 00:00:00
abstract::Studies have identified increased prevalence of vitamin D deficiency in patients with alopecia areata (AA), an autoimmune disease characterized by hair loss, but none have prospectively examined vitamin D status and incident AA. In 55,929 women in the Nurses' Health Study (NHS), we prospectively evaluated the associat...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-016-1687-y
更新日期:2016-11-01 00:00:00
abstract::Human alpha 1(I) and alpha 1(III) procollagen mRNA expression in skin tissue from 15 systemic sclerosis (SSc) patients and from 7 normal control subjects was quantitatively analyzed using in situ hybridization. The grains accumulating in each area, representing procollagen mRNA expression per cell, were counted. To no...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030050458
更新日期:1999-11-01 00:00:00
abstract::A suction blister device with a sensitive thermometer and with a temperature regulator was constructed. Utilizing this device, it was demonstrated that the cold challenge induces an increase in the skin temperature in cold urticaria patients during the cold challenge and a simultaneous release of histamine into the su...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00404624
更新日期:1984-01-01 00:00:00
abstract::Wnt pathway plays an important role in controlling metabolism in cancer cells. It acts as positive modulator for both cell inflammation, through activation of NFκB, and fibrosis, through activation of TGF-β. Therefore, the aim of this study is to investigate the therapeutic effects of blocking Wnt pathway by IWP12 on ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-019-01939-4
更新日期:2019-10-01 00:00:00
abstract::All-trans retinoic acid (ATRA) is known to have beneficial effects on skin. It has been used extensively for the treatment of photodamaged skin. To assess the effects of all-trans retinoic acid on the dermis, specifically its effect on hyaluronate (hyaluronic acid, HA) synthesis and inhibition, tissue-engineered human...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-014-1460-z
更新日期:2014-09-01 00:00:00
abstract::The effects of oral 8-methoxypsoralen-photochemotherapy (PUVA-therapy) on the inflammatory infiltrate in 14 psoriatic skin lesions and on normal skin of 7 controls were investigated by means of autoradiography and planimetry. Under PUVA-therapy, one finds a significant decrease in dermal cells per millimeter lesion in...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00404455
更新日期:1980-01-01 00:00:00
abstract::Metalloproteinase-mediated proteolysis plays an important role during all stages of wound repair. In acute murine wounds, murine collagenase, matrix metalloproteinase (MMP)-9, stromelysin-1, stromelysin-2 and tissue inhibitor of metalloproteinase (TIMP)-1 are strongly induced within 24 h after wounding. At the time of...
journal_title:Archives of dermatological research
pub_type: 杂志文章,评审
doi:10.1007/pl00007450
更新日期:1998-07-01 00:00:00
abstract::Genetic abnormalities for different subtypes of epidermolysis bullosa (EB) have been described. In dominant simplex type EB, mutations of the K5 or K14 gene lead to disruption of basal cells and the formation of bullae. The recessive simplex types include EB with muscular dystrophy due to abnormal plectin, EB without ...
journal_title:Archives of dermatological research
pub_type: 杂志文章,评审
doi:10.1007/s00403-002-0369-0
更新日期:2003-04-01 00:00:00
abstract::Recent evidence indicates that the biologically active metabolite of vitamin D3, 1 alpha,25-dihydroxyvitamin D3 [1 alpha,25(OH)2D3], has an effect on the regulation of the immune response. We investigated whether topical treatment of mice with 1 alpha,25(OH)2D3 influences the contact hypersensitivity (CHS) response to...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00412982
更新日期:1989-01-01 00:00:00
abstract::Classic Refsum disease (RD) is a rare, autosomal recessively-inherited disorder of peroxisome metabolism due to a defect in the initial step in the alpha oxidation of phytanic acid (PA), a C16 saturated fatty acid with four methyl side groups, which accumulates in plasma and lipid enriched tissues (please see van den ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-014-1478-2
更新日期:2014-10-01 00:00:00
abstract::Using a sensitive and modified solid-phase radioimmunoassay for detecting anti-cardiolipin antibodies, sera of 45 patients with lepromatous leprosy were examined. Nine of the 45 (20%) showed positive levels of anti-cardiolipin antibodies. Inhibition tests revealed that these antibodies significantly cross-reacted with...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00407745
更新日期:1986-01-01 00:00:00
abstract::Acrolein and 4-hydroxy-2-nonenal (HNE) are both byproducts of a lipid peroxidation reaction. Actinic elastosis in photodamaged skin of aged individuals is characterized by the accumulation of fragmented elastic fibers in the sun-exposed areas. To study whether a lipid peroxidation reaction is involved in the accumulat...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s004030100239
更新日期:2001-07-01 00:00:00
abstract::Antihistamines are the first-line treatment for chronic urticaria (CU). However, some CU patients are relatively refractory to antihistamines. The mechanism underlying the interindividual variation is still unknown. The α-chain of the high-affinity IgE receptor is crucial to the IgE-mediated allergic response. The pre...
journal_title:Archives of dermatological research
pub_type: 临床试验,杂志文章
doi:10.1007/s00403-014-1525-z
更新日期:2015-03-01 00:00:00
abstract::A low molecular mass cysteine proteinase inhibitor was found and isolated from bovine hoof. Purification of the inhibitor to homogeneity was performed by carboxymethyl-papain-sepharose affinity and DE-52 ion exchange chromatographies. From 15 g of bovine hoof, 0.25 mg of cysteine proteinase inhibitor was isolated. It ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF02505240
更新日期:1996-07-01 00:00:00
abstract::The safety and efficacy of imiquimod 5% cream is being evaluated for the treatment of dysplastic lesions of the epidermis (actinic keratoses, AK). The objective of this clinical study was to describe the pharmacokinetics and safety of topical imiquimod during multiple dosing of AK subjects. A total of 58 adult subject...
journal_title:Archives of dermatological research
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/s00403-004-0465-4
更新日期:2004-06-01 00:00:00
abstract::Three new cromones have been studied that are supposed to be better absorbed and to have a wider spectrum of anti-allergic activity than disodium cromoglycate. Pretreatment with i.d. injection of 10 microgram FPL 52758 significantly reduced the weal and flare reaction induced by specific antigen in 11 patients with at...
journal_title:Archives of dermatological research
pub_type: 临床试验,杂志文章
doi:10.1007/BF00403843
更新日期:1980-01-01 00:00:00
abstract::Vascular endothelial growth factor (VEGF) is believed to play a crucial role in neoplastic angiogenesis. Although the genetic background of basal cell carcinoma (BCC) has been analyzed in some papers, the mechanism of BCC pathogenesis is not fully understood. To the best of our knowledge, VEGF gene polymorphisms have ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-014-1471-9
更新日期:2014-08-01 00:00:00
abstract::Acidic polysaccharides (AP) are released from Propionibacterium acnes I and II during growth. Similar antigens are released from two strains of P. avidum, but in a smaller amount. Furthermore, prostaglandin-like substances (PLS) have been isolated from the lipid fraction of P. acnes. The AP antigens give rise to a pre...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00406418
更新日期:1980-01-01 00:00:00
abstract::To evaluate the proliferative activity of benign, borderline and malignant cutaneous melanocytic neoplasms, 30 cases of malignant melanoma (MM) and 41 cases of naevi were studied by immunostaining using a monoclonal antibody against proliferating cell nuclear antigen (PCNA). PCNA is a nuclear antigen expressed in the ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00372033
更新日期:1992-01-01 00:00:00
abstract::Splenopentin (SP-5: Arg-Lys-Glu-Val-Tyr), a pentapeptide corresponding to the residues 32-36 of the splenic hormone splenin, increases dose-dependently the number of bone marrow colonies (M and GM colonies). Therefore, we tested the stimulatory effect of SP-5 on the recruitment of epidermal Langerhans cells in skin de...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00412738
更新日期:1990-01-01 00:00:00
abstract::A 61-year old woman developed a tumourous nodule in her left leg. Fifteen years ago a similar tumour had been removed in the same localization. Histological examination performed on biopsy material showed bundles of predominantly fusiform tumour cells with nuclear pleomorphism and many mitotic figures. Electron micros...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/BF00446437
更新日期:1978-11-10 00:00:00
abstract::Wound healing could be categorized as a chronic disorder which needs a prompt and effective medication. Nowadays, vascular problems and wound-healing progression studies relay on the role of metformin; however, the exact mechanisms for its beneficial effects are still not completely understood. The aim of the present ...
journal_title:Archives of dermatological research
pub_type: 杂志文章
doi:10.1007/s00403-019-01982-1
更新日期:2020-03-01 00:00:00