Histamine H1-receptor of vascular endothelial cells cultured from guinea pig skin.

abstract：:Skin fibrosis, characterized by excessive fibroblast proliferation and extracellular matrix deposition in the dermis, is the histopathologic hallmark of dermatologic diseases such as systemic sclerosis, hypertrophic scars, and keloids. Effective anti-scarring therapeutics remain an unmet need, underscoring the complex...

journal_title：Archives of dermatological research

authors： Nguyen JK,Austin E,Huang A,Mamalis A,Jagdeo J

更新日期：2020-03-01 00:00:00

abstract：:Certain HPV types have been linked to the genesis and development of premalignant and malignant skin diseases. There have been several contradictory reports on the role of HPV infections in the development of keratoacanthomas (KAs). To further study the involvement of HPVs in the aetiology of KAs, we investigated para...

journal_title：Archives of dermatological research

authors： Lu S,Syrjänen SL,Havu VK,Syrjänen S

更新日期：1996-03-01 00:00:00

abstract：:Thymocyte selection-associated high-mobility group box (TOX) is aberrantly expressed in cutaneous T-cell lymphomas. In a recent study, TOX expression was noted unexpectedly in the follicle center (germinal center) B-cells of reactive lymph nodes and tonsils, used as external controls. To evaluate whether TOX is also e...

journal_title：Archives of dermatological research

authors： Schrader AM,Jansen PM,Willemze R

更新日期：2016-08-01 00:00:00

abstract：:Three per cent boric acid incorporated in an anhydrous, water-emulsifying ointment causes no increase of boron levels in blood and urine during a period of 1-9 days after a single topical application. The same amount of boric acid incorporated in a water-based jelly does cause an increase in blood and urine levels, be...

journal_title：Archives of dermatological research

authors： Stüttgen G,Siebel T,Aggerbeck B

更新日期：1982-01-01 00:00:00

abstract：:To investigate biological characteristics of syringomas, three-dimensional (3-D) architectures of epithelial tumor nests and luminal structures of syringomas, hair follicles, and epidermal basement membrane in skin lesions were reconstructed using a computer stereographic analysis. Each lesion was composed of many sph...

journal_title：Archives of dermatological research

authors： Ito M,Yokoyama H,Ikeda K,Sato Y

更新日期：1990-01-01 00:00:00

abstract：:A significant difference between keloids and hypertrophic scars could be demonstrated by means of acid elution of lymphoid blood cells and immunofluorescence studies. A total of 20 patients (13 patients with keloids and seven with hypertrophic scars) were investigated. All the 13 patients with keloids revealed in the ...

journal_title：Archives of dermatological research

authors： Janssen de Limpens AM,Cormane RH

更新日期：1982-01-01 00:00:00

abstract：:In this study we investigated the influence of keratinocytes on the phenotype of fibroblasts in an in vitro human skin equivalent. Keratinocytes were seeded at the surface of fibroblast-populated mechanically restrained type I collagen gels (lattices). Lattices without keratinocytes were handled in parallel as control...

journal_title：Archives of dermatological research

authors： Lacroix M,Bovy T,Nusgens BV,Lapière CM

更新日期：1995-01-01 00:00:00

abstract：:Bradykinin has long been postulated to have a major role in physiologic human pain production. We have developed a method to systematically quantify the algogenic response to bradykinin in human skin by the direct application of bradykinin to suction blister bases. After determination of the pain threshold to bradykin...

journal_title：Archives of dermatological research

authors： Schneider BK,Morelli JG,Vavrek RJ,Stewart JM,Weston WL

更新日期：1992-01-01 00:00:00

abstract：:The aim of this study was to investigate the effects of Cervi cornus Colla (CCC) in the reconstruction of skin equivalent (SE). H&E staining showed that SE containing hyaluronic acid (HA) or HA and CCC had a thicker epidermis than the control SE. Immunohistochemical staining showed that p63 was mainly present at the b...

journal_title：Archives of dermatological research

authors： Kim J,Jeong HS,Li H,Baek KJ,Kwon NS,Yun HY,Choi HR,Park KC,Kim DS

更新日期：2013-01-01 00:00:00

abstract：:In a group of 40 patients suffering from wide-spread psoriasis oral administration of a retinoid (Ro 10-9359) was followed by PUVA therapy. The clearance rate was increased by 30% as compared to PUVA alone. Except for cheilitis no side effects were seen. Histological analysis in 20 patients before, during and after th...

journal_title：Archives of dermatological research

authors： Heidbreder G,Christophers E

更新日期：1979-05-04 00:00:00

abstract：:Artificial light at night (LAN) is a pervasive phenomenon in today's society, and the detrimental consequences of LAN exposure are becoming apparent. LAN is associated with the increased incidence of metabolic disorders, cancers, mood alterations, and immune dysfunction in mammals. Consequently, we examined the effect...

journal_title：Archives of dermatological research

authors： Walker WH 2nd,Meléndez-Fernández OH,Nelson RJ

更新日期：2019-09-01 00:00:00

abstract：:Exposure of hairless mice to the light of a germicidal lamp (254 nm) under conditions which are known to induce epidermal DNA synthesis, cell proliferation, and polyamine metabolism produced a marked increase of polyamine excretion in the urine which lasted for many days. The increase was about the same for free and a...

journal_title：Archives of dermatological research

authors： Seiler N,Richards W,Knödgen B

更新日期：1981-01-01 00:00:00

abstract：:Mycosis fungoides was observed in a 71-year-old male with Mediterranean lymphoma, a B-cell malignancy. It is proposed that this association is not incidental since hypergammaglobulinaemia and even monoclonal gammopathies have repeatedly been described in cutaneous T-cell lymphomas. Mediterranean lymphoma might have re...

journal_title：Archives of dermatological research

authors： Cassuto JP,Kövary PM,Campagni JP,Simony J,Maiolini R,Schneider M

更新日期：1981-01-01 00:00:00

abstract：:A 50-year-old male patient had three episodes of acrally located purpura within 12 years without any other symptoms. The first two episodes which lasted several months coincided with the intake of beta-blockers; the third episode developed after a respiratory infection. A cryofibrinogenemia was found without any evide...

journal_title：Archives of dermatological research

authors： Brüngger A,Brülisauer M,Mitsuhashi Y,Schneider BV,Bollinger A,Schnyder UW

更新日期：1987-01-01 00:00:00

abstract：:Fast antigen is a cell surface protein that mediates apoptosis. Using immunohistological, flow cytometry and electron microscopic analyses, we investigated the expression of Fas antigen on various skin tissues, and on cultured SV40-transformed human epidermal keratinocyte cell line KJD and human skin squamous cell car...

journal_title：Archives of dermatological research

authors： Oishi M,Maeda K,Sugiyama S

更新日期：1994-01-01 00:00:00

abstract：:Transcutaneous oxygen pressure (TcPO2) and skin blood flow (as evaluated by laser doppler) (LD) were investigated in 24 systemic sclerosis (SSc) patients in sclerotic skin (dorsal aspect of the hand) and non-sclerotic skin (interscapular region) and in 24 controls matched for sex and age for the same sites. The two pa...

journal_title：Archives of dermatological research

authors： Valentini G,Leonardo G,Moles DA,Apaia MR,Maselli R,Tirri G,Del Guercio R

更新日期：1991-01-01 00:00:00

abstract：:The aim of this study was to investigate the presence and density of the nerve fibre-marker protein gene product 9.5 (PGP 9.5), with immunohistochemistry, in skin from patients with hidradenitis suppurativa (HS). Punch biopsies were obtained from 16 patients; 10 with involvement of the groin and six with axillary dise...

journal_title：Archives of dermatological research

authors： Sartorius K,Emtestam L,Lapins J,Johansson O

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Human VAT-1 (hVAT-1) is a homologue of the synaptic vesicle membrane protein of Torpedo californica. Its coding gene is located near the BRCA1 locus and thus hVAT-1 may be linked to an inherited predisposition to breast and ovary cancer. However, the hVAT-1 protein expression pattern in normal epith...

journal_title：Archives of dermatological research

authors： Koch J,Foekens J,Timmermans M,Fink W,Wirzbach A,Kramer MD,Schaefer BM

更新日期：2003-09-01 00:00:00

abstract：:To investigate the relationship between smoking and primary basal cell carcinoma (BCC), we analyzed data from a 16 year prospective study among randomly selected adults in Nambour, Queensland, Australia. Participants underwent a skin examination in 1992 and took part in an intervention study and follow-up. Information...

journal_title：Archives of dermatological research

authors： Hughes MC,Olsen CM,Williams GM,Green AC

更新日期：2014-11-01 00:00:00

abstract：:The goal of this study is to investigate commercially available cosmetics (foundations, skin care creams) which also claim to include a sun protection factor (SPF). Are these products, which are not considered sunscreen products, helpful or could they be harmful? Using an in vitro method, we tested the effectiveness o...

journal_title：Archives of dermatological research

authors： Séhédic D,Hardy-Boismartel A,Couteau C,Coiffard LJ

更新日期：2009-09-01 00:00:00

abstract：:Two male patients with longstanding contact sensitivity to chromium were treated with PUVA. One patient, suffering from concomitant photosensitivity, reacted very favorably; his skin lesions cleared and light tolerance increased. This was paralleled by a decrease in the photopatch test reactivity and by the extinction...

journal_title：Archives of dermatological research

authors： Jansén CT,Viander M,Kalimo K,Soppi AM,Soppi E

更新日期：1981-01-01 00:00:00

abstract：:The expression of IL-8 in psoriasis has been clearly shown with the use of immunocytochemical, RT-PCR and in situ hybridization methods. The presence of its ligand, the IL-8 receptor, has been demonstrated by the RT-PCR technique. We report here a study of the expression of both IL-8 type A and B receptors by immunohi...

journal_title：Archives of dermatological research

authors： Beljaards RC,Van Beek P,Nieboer C,Stoof TJ,Boorsma DM

更新日期：1997-07-01 00:00:00

abstract：:Bullous pemphigoid (BP) is a chronic debilitating autoimmune blistering disease that frequently occurs in the elderly population. Previous studies have suggested a high morbidity and mortality associated with BP. However, relatively few studies have investigated prognostic factors of BP mortality, and they showed cons...

journal_title：Archives of dermatological research

authors： Liu YD,Wang YH,Ye YC,Zhao WL,Li L

更新日期：2017-07-01 00:00:00

abstract：:Pemphigus is a general term for a rare group of autoimmune diseases which result in the formation of blisters on the skin and oral cavity. Although there is no way to prevent autoimmune diseases, some factors may trigger pemphigus initiation in susceptible individuals or be exacerbated in affected patients. Recognitio...

journal_title：Archives of dermatological research

authors： Tavakolpour S

更新日期：2018-03-01 00:00:00

abstract：:Scleroderma is a chronic fibrosing disease, in which an early inflammatory reaction precedes the fibrotic response. Systematic analysis of the pathways involved in the development of the disease together with information derived from novel animal models have helped to better understand the mechanisms that trigger and ...

journal_title：Archives of dermatological research

authors： Eckes B,Hunzelmann N,Moinzadeh P,Krieg T

更新日期：2007-06-01 00:00:00

abstract：:A recently described endogenous proteolytic process in pieces of human plantar stratum corneum incubated in vitro has been further studied. This process leads to a decrease in cohesion between the cells that had been facing outwards in vivo. Using two methods, that differed with respect to efficiency, to detach surfac...

journal_title：Archives of dermatological research

authors： Lundström A,Egelrud T

更新日期：1990-01-01 00:00:00

abstract：:We conducted a nationwide record-linked study using all English NHS hospital admission data and mortality statistics from 1999 to 2011 to evaluate the risk of concurrent or subsequent bullous pemphigoid (BP) in a cohort of 2,873,720 individuals with malignant cancers, when compared with a reference cohort. We calculat...

journal_title：Archives of dermatological research

authors： Ong E,Goldacre R,Hoang U,Sinclair R,Goldacre M

更新日期：2014-01-01 00:00:00

abstract：:Centromere protein B (CENP-B), which is an alphoid DNA binding protein, is the target antigen in autoimmune disease patients (often those with scleroderma). In this study, we analysed activities of anti-CENP-B-DNA complex in anticentromere antibody (ACA)-positive patients using DNA immunoprecipitation with purified CE...

journal_title：Archives of dermatological research

authors： Muro Y,Matsumoto Y,Ohashi M

更新日期：1992-01-01 00:00:00

abstract：:Despite the fact that polymorphous light eruption (PLE) is the most common photodermatosis, affecting 15% of healthy people in the UK, its pathogeny remains unclear. The condition is more frequent in females and begins often in young adults and in mid-adult life. The mechanism of PLE is under active research as shown ...

journal_title：Archives of dermatological research

authors： Aubin F

更新日期：2004-10-01 00:00:00

abstract：:Splenopentin (SP-5: Arg-Lys-Glu-Val-Tyr), a pentapeptide corresponding to the residues 32-36 of the splenic hormone splenin, increases dose-dependently the number of bone marrow colonies (M and GM colonies). Therefore, we tested the stimulatory effect of SP-5 on the recruitment of epidermal Langerhans cells in skin de...

journal_title：Archives of dermatological research

authors： Gruner S,Diezel W,Strunk D,Zwirner A,Sönnichsen N,Anhalt GJ

更新日期：1990-01-01 00:00:00