Anticentromere-protein-B--DNA complex activities in anticentromere antibody-positive patients.

abstract：:Three per cent boric acid incorporated in an anhydrous, water-emulsifying ointment causes no increase of boron levels in blood and urine during a period of 1-9 days after a single topical application. The same amount of boric acid incorporated in a water-based jelly does cause an increase in blood and urine levels, be...

journal_title：Archives of dermatological research

authors： Stüttgen G,Siebel T,Aggerbeck B

更新日期：1982-01-01 00:00:00

abstract：:Filaggrin, a basic protein of the stratum corneum, was named as such because of its capability to aggregate keratin intermediate filaments in vitro. To investigate its filament-aggregating capability in vivo, we performed immunoelectron microscopy in three autosomal dominant genodermatoses serving as in vivo models of...

journal_title：Archives of dermatological research

authors： Weidenthaler B,Hausser I,Anton-Lamprecht I

更新日期：1993-01-01 00:00:00

abstract：:Psoriasis, a chronic inflammatory skin disease, is associated with oxidative stress of serum lipoproteins. In psoriatic children we evaluated the activity and levels of myeloperoxidase, the activity of paraoxonase-1 (PON1) and biochemical markers of lipid peroxidation, to investigate wether an unbalance between oxidan...

journal_title：Archives of dermatological research

authors： Bacchetti T,Simonetti O,Ricotti F,Offidani A,Ferretti G

更新日期：2020-01-01 00:00:00

abstract：:The aim of the present study was to investigate the influence of three different retinoids, isotretinoin, etretinate and acitretin, on the mitogenic response of peripheral blood mononuclear cells (PBMCs) to PHA and PMA in vitro. All three retinoids at high concentrations (10(-4)M) significantly inhibited the mitogenic...

journal_title：Archives of dermatological research

authors： Chaidaroglou A,Degiannis D,Koniavitou K,Georgiou S,Tsambaos D

更新日期：1998-04-01 00:00:00

abstract：:Bullous pemphigoid (BP) is a chronic debilitating autoimmune blistering disease that frequently occurs in the elderly population. Previous studies have suggested a high morbidity and mortality associated with BP. However, relatively few studies have investigated prognostic factors of BP mortality, and they showed cons...

journal_title：Archives of dermatological research

authors： Liu YD,Wang YH,Ye YC,Zhao WL,Li L

更新日期：2017-07-01 00:00:00

abstract：:Investigations on the nutrient requirements of Malassezia yeasts led to the preparation of a new minimal medium consisting of an amino nitrogen and a lipid source, which only allowed the growth of the species M. furfur. Carbohydrates, electrolytes, vitamins and trace elements were not required. Using the basal medium,...

journal_title：Archives of dermatological research

authors： Mayser P,Imkampe A,Winkeler M,Papavassilis C

更新日期：1998-05-01 00:00:00

abstract：:This study probes the extent of coupling between the reversal of epidermal hyperproliferation induced by essential fatty acid (EFA) deficiency in guinea pigs, the hydrolysis of epidermal phosphatidylinositol 4,5-bisphosphate (PtdIns4,5P2), and the rapid formation of inositol triphosphate (InsP3). Our data revealed tha...

journal_title：Archives of dermatological research

authors： Tang W,Ziboh VA

更新日期：1988-01-01 00:00:00

abstract：:Vitiligo is an acquired clinical conundrum, characterized by white areas on the skin due to loss of functional melanocytes. Various studies demonstrated that vitiligo is associated with fewer risk of skin cancer but no exact molecular explanation for this interesting observation has been described. This article review...

journal_title：Archives of dermatological research

authors： Feily A,Pazyar N

更新日期：2011-11-01 00:00:00

abstract：:Studies have identified increased prevalence of vitamin D deficiency in patients with alopecia areata (AA), an autoimmune disease characterized by hair loss, but none have prospectively examined vitamin D status and incident AA. In 55,929 women in the Nurses' Health Study (NHS), we prospectively evaluated the associat...

journal_title：Archives of dermatological research

authors： Thompson JM,Li T,Park MK,Qureshi AA,Cho E

更新日期：2016-11-01 00:00:00

abstract：:Histamine is released from mast cells in the skin, causing urticaria and itching. However, little is known about the roles of histamine in development of eczematous lesions in contact dermatitis. Effects of histamine on development of eczematous lesions in contact dermatitis were assessed using histamine-deficient mic...

journal_title：Archives of dermatological research

authors： Seike M,Takata T,Ikeda M,Kodama H,Terui T,Ohtsu H

更新日期：2005-08-01 00:00:00

abstract：:Wound healing could be categorized as a chronic disorder which needs a prompt and effective medication. Nowadays, vascular problems and wound-healing progression studies relay on the role of metformin; however, the exact mechanisms for its beneficial effects are still not completely understood. The aim of the present ...

journal_title：Archives of dermatological research

authors： Tawfeek HM,Abou-Taleb DAE,Badary DM,Ibrahim M,Abdellatif AAH

更新日期：2020-03-01 00:00:00

abstract：:Nickel, cobalt and chromium are metals very often implicated in allergic contact dermatitis. In vivo, keratinocytes, which are the first target cells, can be directly activated to participate in the local reaction, especially through the expression of the membrane antigen ICAM-1, a ligand of the leucocyte antigen LFA-...

journal_title：Archives of dermatological research

authors： Guéniche A,Viac J,Lizard G,Charveron M,Schmitt D

更新日期：1994-01-01 00:00:00

abstract：:The penetration and permeation of the recombinant protein plasminogen activator inhibitor type 2 (PAI-2) in two formulations, one containing a penetration enhancer, into the psoriatic and uninvolved skin of eight patients with plaque-type psoriasis were investigated. Penetration and permeation of PAI-2 were measured b...

journal_title：Archives of dermatological research

authors： Gould AR,Sharp PJ,Smith DR,Stegink AJ,Chase CJ,Kovacs JC,Penglis S,Chatterton BE,Bunn CL

更新日期：2003-11-01 00:00:00

abstract：:The phospholipids of the skin are difficult to quantify because they represent only a small fraction of the skin tissue. In this study, 31P nuclear magnetic resonance, which permits precise profiling of these phospholipids, was used to compare the phospholipids of upper eyelid epidermal and dermal lipid extracts (n = ...

journal_title：Archives of dermatological research

authors： Greiner JV,Glonek T,Townsend DJ,Hearn SL

更新日期：1998-06-01 00:00:00

abstract：:Congenital atrichia (AUC) is a form of isolated alopecia with an autosomal recessive mode of inheritance. Patients are born with normal hair but this is shed almost completely during the first weeks or months of life and never regrows. In many families the development of papular lesions is noted as an additional pheno...

journal_title：Archives of dermatological research

authors： Betz RC,Indelman M,Pforr J,Schreiner F,Bauer R,Bergman R,Lentze MJ,Nöthen MM,Cichon S,Sprecher E

更新日期：2007-06-01 00:00:00

abstract：:HaCaT keratinocytes differ from normal human epidermal keratinocytes (HEK) by constitutive expression of differentiation markers which are normally suppressed by vitamin A. In search of an explanation for this discrepancy we compared the vitamin A content, the expression of retinoid-binding proteins, and the vitamin A...

journal_title：Archives of dermatological research

authors： Törmä H,Rollman O,Vahlquist A

更新日期：1999-06-01 00:00:00

abstract：:We conducted a nationwide record-linked study using all English NHS hospital admission data and mortality statistics from 1999 to 2011 to evaluate the risk of concurrent or subsequent bullous pemphigoid (BP) in a cohort of 2,873,720 individuals with malignant cancers, when compared with a reference cohort. We calculat...

journal_title：Archives of dermatological research

authors： Ong E,Goldacre R,Hoang U,Sinclair R,Goldacre M

更新日期：2014-01-01 00:00:00

abstract：:HLA types were determined in 19 patients and 9 healthy members of 2 Danish families with hereditary angioneurotic edema. The study revealed no connections between hereditary angioneurotic edema and the HLA system. ...

journal_title：Archives of dermatological research

authors： Eggert J,Zachariae H,Svejgaard E,Svejgaard A,Kissmeyer-Nielsen F

更新日期：1982-01-01 00:00:00

abstract：:Mycosis fungoides was observed in a 71-year-old male with Mediterranean lymphoma, a B-cell malignancy. It is proposed that this association is not incidental since hypergammaglobulinaemia and even monoclonal gammopathies have repeatedly been described in cutaneous T-cell lymphomas. Mediterranean lymphoma might have re...

journal_title：Archives of dermatological research

authors： Cassuto JP,Kövary PM,Campagni JP,Simony J,Maiolini R,Schneider M

更新日期：1981-01-01 00:00:00

abstract：:Fast antigen is a cell surface protein that mediates apoptosis. Using immunohistological, flow cytometry and electron microscopic analyses, we investigated the expression of Fas antigen on various skin tissues, and on cultured SV40-transformed human epidermal keratinocyte cell line KJD and human skin squamous cell car...

journal_title：Archives of dermatological research

authors： Oishi M,Maeda K,Sugiyama S

更新日期：1994-01-01 00:00:00

abstract：:This study was designed in order to prove on a large-scale basis the efficacy of oral photochemotherapy (PUVA) in the prevention of polymorphous light eruption (PLE), to work out indication criteria for PUVA treatment of this disease, and to establish a simple method based on anamnestic data to differentiate UVA from ...

journal_title：Archives of dermatological research

authors： Gschnait F,Schwarz T,Ladich I

更新日期：1983-01-01 00:00:00

abstract：:The exposure of naked unprotected skin to solar radiation may result in numerous acute and chronic undesirable effects. Evidence suggests that silymarin, a standardized extract from Silybum marianum (L.) Gaertn. seeds, and its major component silybin suppress UVB-induced skin damage. Here, we aimed to investigate the ...

journal_title：Archives of dermatological research

authors： Rajnochová Svobodová A,Gabrielová E,Ulrichová J,Zálešák B,Biedermann D,Vostálová J

更新日期：2019-08-01 00:00:00

abstract：:We previously showed that the homeodomain protein HOXC13 is involved in the expression control of the early human hair keratin genes hHa5 and hHa2, which contain specific HOXC13 binding sites in their proximal promoters. Hox specificity is generally thought to be enhanced by the interaction with members of the TALE su...

journal_title：Archives of dermatological research

authors： Jave-Suárez LF,Schweizer J

更新日期：2006-02-01 00:00:00

abstract：:Ichthyosis Follicularis, Atrichia, and Photophobia (IFAP) is a severe rare genetic disorder caused by mutations in the gene encoding the Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2). Olmsted syndrome is another rare genetic disease with overlapping clinical features caused by mutations in the gene en...

journal_title：Archives of dermatological research

authors： Nemer G,Safi R,Kreidieh F,Usta J,Bergqvist C,Ballout F,Btadini W,Hamzeh N,Abbas O,Kibbi AG,Shimomura Y,Kurban M

更新日期：2017-10-01 00:00:00

abstract：:The distribution coefficient of caffeine (water/n-Octanol) and the estimation of caffeine in urine after local application indicate to a high permeation rate of caffeine through the skin. This could be confirmed by using different vehicles in vivo and in vitro. 14C labeled caffeine penetrates rapidly the epidermis and...

journal_title：Archives of dermatological research

authors： Zesch A,Schaefer H,Stüttgen G

更新日期：1979-11-01 00:00:00

abstract：:Exposure to a dry environment leads to depletion of water from the peripheral stratum corneum layers in a process dependent on the relative humidity (RH) and the intrinsic properties of the tissue. We hypothesized that by modulating the water content of the stratum corneum in the surface layers, RH effects the rate of...

journal_title：Archives of dermatological research

authors： Watkinson A,Harding C,Moore A,Coan P

更新日期：2001-09-01 00:00:00

abstract：:Human eccrine sweat glands were embedded in Lowicryl K4M. Cytokeratin proteins and blood group H antigen were localized by applying a postembedding immunogold method using a monoclonal antikeratin antibody and the lectin Ulex europaeus I. The antikeratin antibody labeled intermediate filaments in the secretory coil an...

journal_title：Archives of dermatological research

authors： Metzler G,Schaumburg-Lever G,Liebig K

更新日期：1990-01-01 00:00:00

abstract：:Atopic dermatitis (AD) can be exacerbated by various factors, including emotional stress, scratching and sweating. The aim of the present study was to evaluate the hypothesis that the inflammatory reaction in AD is also neurogenic. For this purpose, the levels of vasoactive intestinal polypeptide were measured radioim...

journal_title：Archives of dermatological research

authors： Pincelli C,Fantini F,Romualdi P,Lesa G,Giannetti A

更新日期：1991-01-01 00:00:00

abstract：:Using a sensitive and modified solid-phase radioimmunoassay for detecting anti-cardiolipin antibodies, sera of 45 patients with lepromatous leprosy were examined. Nine of the 45 (20%) showed positive levels of anti-cardiolipin antibodies. Inhibition tests revealed that these antibodies significantly cross-reacted with...

journal_title：Archives of dermatological research

authors： Furukawa F,Kashihara M,Imamura S,Ohshio G,Hamashima Y

更新日期：1986-01-01 00:00:00

abstract：:Intercellular adhesion molecule-1 (ICAM-1) is regularly expressed or inducible on all major cutaneous cell populations including Langerhans cells, keratinocytes, endothelial cells and dermal fibroblasts. ICAM-1 is induced in the skin under inflammatory conditions and plays an important role in the activation of T cell...

journal_title：Archives of dermatological research

authors： Chatelain R,Wollenberg A,Martin C,Panhans-Gross A,Bieber T,Degitz K,Heckmann M

更新日期：1998-09-01 00:00:00