Studies on the role of polymorphonuclear leukocyte granule elastase in Arthus reaction.

abstract：:Solar ultraviolet (UV) irradiation causes damages on human skin and premature skin aging (photoaging). UV-induced reduction of type I collagen in dermis is widely considered primarily induction of wrinkled appearance of photoaging skin. Type I procollagen synthesis is reduced under UV irradiation by blocking transform...

journal_title：Archives of dermatological research

authors： Tanaka H,Yamaba H,Kosugi N,Mizutani H,Nakata S

更新日期：2008-04-01 00:00:00

abstract：:Recently, we described a novel fibroblast-restricted monoclonal antibody (mAb AS02) that recognizes a membrane-bound antigen. Characterization and isolation of the corresponding antigen showed that mAb AS02 recognized a protein on human fibroblasts that is highly homologous or identical to human Thy-1 antigen (CD90). ...

journal_title：Archives of dermatological research

authors： Saalbach A,Kraft R,Herrmann K,Haustein UF,Anderegg U

更新日期：1998-07-01 00:00:00

abstract：:Flushing in rosacea has been investigated by means of (a) pharmacological inhibition of some possible chemical mediators and (b) titration of bradykinin as a possible effector directly in the blood. Clonidine-inhibited flushing was seen in all patients (mean 45%), other drugs had poorer results. Bradykinin increased i...

journal_title：Archives of dermatological research

authors： Guarrera M,Parodi A,Cipriani C,Divano C,Rebora A

更新日期：1982-01-01 00:00:00

abstract：:Forty-one male guinea pigs were treated orally with high doses of aromatic retinoid (Ro 10-9359) 25 mg/kg/day in oleum arachidis for 6 weeks. Twenty-three animals were investigated at the end of this treatment. The remaining 18 animals were investigated after an additional retinoid-free interval of 6 weeks. A control ...

journal_title：Archives of dermatological research

authors： Tsambaos D,Hundeiker M,Mahrle G,Orfanos CE

更新日期：1980-01-01 00:00:00

abstract：:Centromere protein B (CENP-B), which is an alphoid DNA binding protein, is the target antigen in autoimmune disease patients (often those with scleroderma). In this study, we analysed activities of anti-CENP-B-DNA complex in anticentromere antibody (ACA)-positive patients using DNA immunoprecipitation with purified CE...

journal_title：Archives of dermatological research

authors： Muro Y,Matsumoto Y,Ohashi M

更新日期：1992-01-01 00:00:00

abstract：:Recently, medium-dose UVA1 phototherapy (50 J/cm2) has been introduced as an effective treatment for severe atopic dermatitis (AD). In order to further elucidate the mechanisms by which medium-dose UVA1 irradiation leads to an improvement in skin status in patients with AD, biopsy specimens from ten patients before an...

journal_title：Archives of dermatological research

authors： Breuckmann F,Pieck C,Kreuter A,Bacharach-Buhles M,Mannherz HG,Altmeyer P,von Kobyletzki G

更新日期：2001-04-01 00:00:00

abstract：:The pathogenetic mechanisms in vitiligo have not been completely clarified. One of the major hypotheses in the pathogenesis of vitiligo is the oxidative stress hypothesis. The active or stable phase of vitiligo is defined on the basis of the progression or appearance of new lesions in the last 3 months and the absence...

journal_title：Archives of dermatological research

authors： Ines D,Sonia B,Riadh BM,Amel el G,Slaheddine M,Hamida T,Hamadi A,Basma H

更新日期：2006-09-01 00:00:00

abstract：:Using the sebum-absorbent tape technique, we have disclosed five different patterns of follicular sebum excretion rate (SER). These are the infantile, pubertal, acne, adult and aging patterns, distinguished by different densities of active sebaceous follicles, by distinct levels of follicular SER and by the relative s...

journal_title：Archives of dermatological research

authors： Piérard GE,Piérard-Franchimont C,Lê T,Lapière C

更新日期：1987-01-01 00:00:00

abstract：:The case of a 44-year-old man with a primary cutaneous large B-cell non-Hodgkin's lymphoma of the scalp is reported. His mother died of gastric lymphoma and his sib brother is in a 20-year remission of T-cell lymphoma. The patient presented with a 16-year history of occipital and parietal alopecia and a recently worse...

journal_title：Archives of dermatological research

authors： Colovic N,Jurisic V,Terzic T,Atkinson HD,Colovic M

更新日期：2009-10-01 00:00:00

abstract：:The adenylate cyclase system of an established human trichilemmoma cell line was investigated. Stimulators of human epidermal adenylate cyclase system, epinephrine, histamine, adenosine, and prostaglandin E increased cyclic AMP levels of the trichilemmoma cells. The effects of epinephrine, histamine, and adenosine wer...

journal_title：Archives of dermatological research

authors： Tsutsui M,Iizuka H,Ohkawara A,Adachi K,Kanzaki T

更新日期：1987-01-01 00:00:00

abstract：:Polymorphonuclear leukocytes from patients with psoriasis demonstrated a significantly enhanced chemotactic responsiveness to zymosan-activated human serum as compared to granulocytes from healthy volunteers. Furthermore, psoriatic peripheral blood mononuclear cells stimulated with concanavalin a produced an increased...

journal_title：Archives of dermatological research

authors： Csató M,Dobozy A,Hunyadi J,Kenderessy SA,Simon N

更新日期：1981-01-01 00:00:00

abstract：:Hydroperoxides of d-limonene were shown to be potent contact allergens when studied in guinea-pigs. Limonene-2-hydroperoxide (2-hydroperoxy-p-mentha-6,8-diene, a mixture of trans and cis isomers) was synthesized for the first time. The ratio between the trans and cis forms was 3:1. These two hydroperoxides were identi...

journal_title：Archives of dermatological research

authors： Karlberg AT,Shao LP,Nilsson U,Gäfvert E,Nilsson JL

更新日期：1994-01-01 00:00:00

abstract：:Close contacts between mast cells (MC) and nerve fibers have previously been demonstrated in normal and inflamed skin by light and electron microscopy. A key step for any study in MC-nerve interactions in situ is to simultaneously visualize both communication partners, preferably with the option of double labelling th...

journal_title：Archives of dermatological research

authors： Botchkarev VA,Eichmüller S,Peters EM,Pietsch P,Johansson O,Maurer M,Paus R

更新日期：1997-04-01 00:00:00

abstract：:Two male patients with longstanding contact sensitivity to chromium were treated with PUVA. One patient, suffering from concomitant photosensitivity, reacted very favorably; his skin lesions cleared and light tolerance increased. This was paralleled by a decrease in the photopatch test reactivity and by the extinction...

journal_title：Archives of dermatological research

authors： Jansén CT,Viander M,Kalimo K,Soppi AM,Soppi E

更新日期：1981-01-01 00:00:00

abstract：:We have examined the relationship between topical psoriasis treatment and the activity of the mixed function oxidase, aryl hydrocarbon hydroxylase (AHH), in peripheral blood monocytes and lymphocytes from 20 patients with psoriasis. These data were compared to monocyte and lymphocyte AHH activity measured in 20 normal...

journal_title：Archives of dermatological research

authors： Kraemer KH,Robinson RC,Tarone RE,Protic-Sabljic M,Gelboin HV

更新日期：1984-01-01 00:00:00

abstract：:Currently, there are no accurate and simple methods available to measure this risk of atrophy in patients treated with topical glucocorticosteroids. In the present clinical trial, we validated a new score (Dermaphot(®) score) to assess the atrophogenic potential of glucocorticosteroids. 36 healthy adult volunteers wer...

journal_title：Archives of dermatological research

authors： Hofmann M,Salgo R,Aschoff R,Luger TA,Meurer M,Bräutigam M,Thaci D

更新日期：2013-04-01 00:00:00

abstract：:Using a sensitive and modified solid-phase radioimmunoassay for detecting anti-cardiolipin antibodies, sera of 45 patients with lepromatous leprosy were examined. Nine of the 45 (20%) showed positive levels of anti-cardiolipin antibodies. Inhibition tests revealed that these antibodies significantly cross-reacted with...

journal_title：Archives of dermatological research

authors： Furukawa F,Kashihara M,Imamura S,Ohshio G,Hamashima Y

更新日期：1986-01-01 00:00:00

abstract：:It has been suggested that free fatty acids (FFA) such as palmitate, which are secreted from enlarged adipocytes in the subcutaneous fat of obese subjects, serve as a link between obesity and altered skin functions. Cyclooxygenease-2 (COX-2) and prostanoids participate in the induction of impaired dermal function. In ...

journal_title：Archives of dermatological research

authors： Oh E,Yun M,Kim SK,Seo G,Bae JS,Joo K,Chae GT,Lee SB

更新日期：2014-05-01 00:00:00

abstract：:The rhino mouse comedolytic model and the hairless mouse photoaging model are established animal models for screening the in vivo activity of retinoids. However, the expression of the retinoic acid receptors (RARs) and cellular retinoic acid-binding proteins (CRABPs), known to regulate retinoid activity, is not comple...

journal_title：Archives of dermatological research

authors： Beehler BC,Chen S,Tramposch KM

更新日期：1995-01-01 00:00:00

abstract：:Scleroderma is a heterogeneous disease with a complex etiology. As more information is gained about the underlying mechanisms and the improved classifications of scleroderma subtypes, treatments can be better personalized. Improving scleroderma patients' early diagnosis before end organ manifestations occur should imp...

journal_title：Archives of dermatological research

authors： Brady SM,Shapiro L,Mousa SA

更新日期：2016-09-01 00:00:00

abstract：:Previous studies showed an association between various dermatological diseases and epicardial fat thickness (EFT). However, EFT, which has been accepted as a cardiometabolic risk factor in recent years, has not been studied in the context of hidradenitis suppurativa (HS). Therefore, we aimed to determine whether EFT i...

journal_title：Archives of dermatological research

authors： Alatas ET,Biteker M,Alatas OD

更新日期：2020-09-01 00:00:00

abstract：:Ionotrope glutamate receptors of the N-methyl-D-aspartate (NMDA) receptor type are expressed on keratinocytes and influence the intracellular calcium concentration. The importance of NMDA receptors in pathophysiological processes in the skin is, however, still unclear. Epidermal distribution patterns of NMDA receptors...

journal_title：Archives of dermatological research

authors： Fischer M,William T,Helmbold P,Wohlrab J,Marsch WCh

更新日期：2004-09-01 00:00:00

abstract：:The study aimed at detecting differentially expressed proteins in the stratum corneum of dandruff versus non-dandruff scalps to better understand dandruff aetiology. iTRAQ-based quantitative proteomic analysis revealed a total of 68 differentially expressed biomarkers. A detailed analysis of their known physiological ...

journal_title：Archives of dermatological research

authors： Cavusoglu N,Delattre C,Donovan M,Bourassa S,Droit A,El Rawadi C,Jourdain R,Bernard D

更新日期：2016-11-01 00:00:00

abstract：:Pathological alterations of capillaries, accelerated epidermopoesis, increased rate and extent of metabolism in the psoriatic lesion and first manifestation of psoriasis rarely in the first 20 years of life made us decide to investigate the human growth hormone (STH) in blood serum. In 70 patients suffering from psori...

journal_title：Archives of dermatological research

authors： Weber G,Neidhardt M,Schmidt A,Geiger A

更新日期：1981-01-01 00:00:00

abstract：:Localized scleroderma (LoSc) is rare connective tissue disease that manifests with inflammation and fibrosis of the skin. Depending on the LoSc subtype, adjacent structures such as subcutaneous tissue, fascia, muscles, bones may be affected. The hallmark of fibrosis is tissue remodelling with excess deposition of extr...

journal_title：Archives of dermatological research

authors： Wolska-Gawron K,Bartosińska J,Krasowska D

更新日期：2020-07-01 00:00:00

abstract：:The aim of the present study was to investigate the influence of three different retinoids, isotretinoin, etretinate and acitretin, on the mitogenic response of peripheral blood mononuclear cells (PBMCs) to PHA and PMA in vitro. All three retinoids at high concentrations (10(-4)M) significantly inhibited the mitogenic...

journal_title：Archives of dermatological research

authors： Chaidaroglou A,Degiannis D,Koniavitou K,Georgiou S,Tsambaos D

更新日期：1998-04-01 00:00:00

abstract：:An ultrastructural study of the skin lesion of a young patient affected by pseudo-Kaposi's sarcoma of the Bluefarb-Stewart type (BSS) is reported. The neoplasm consisted of a proliferation of vascular structures mostly consisting of a solid bud of endothelial cells surrounded by a thinned and polystratified basement m...

journal_title：Archives of dermatological research

authors： Fimiani M,Simoni S,Miracco C,De Santi M,Luzi P,Andreassi L

更新日期：1989-01-01 00:00:00

abstract：:Previous studies have demonstrated that permeability barrier disruption by acetone treatment significantly enhances skin permeability to both hydrophilic and amphipathic compounds, but not to highly lipophilic compounds. The purpose of the present study was to investigate the dependence of permeability on molecular we...

journal_title：Archives of dermatological research

authors： Tsai JC,Hung PL,Sheu HM

更新日期：2001-06-01 00:00:00

abstract：:Eleven dysplastic melanocytic naevi with various degrees of dysplasia, as judged by light microscopy, were studied by transmission electron microscopy, and their intra-epidermal melanocytes compared with those of five superficial spreading melanomas and seven common benign naevocellular naevi. Intra-epidermal melanocy...

journal_title：Archives of dermatological research

authors： Langer K,Rappersberger K,Steiner A,Konrad K,Wolff K

更新日期：1990-01-01 00:00:00

abstract：:Patients with atopic dermatitis (AD) often present with dry skin, and the reduced secretion of sebum may be responsible for the impaired skin barrier function. A sebum check film enables the patient to self-evaluate the skin sebum content. This study compared the sebum check film with a sebumeter. The skin sebum conte...

journal_title：Archives of dermatological research

authors： Furuichi M,Makino T,Matsunaga K,Hamade E,Yokoi H,Shimizu T

更新日期：2010-11-01 00:00:00