Polymorphonuclear granulocyte chemotaxis and chemotactic factor generation by concanavalin A-stimulated peripheral blood mononuclear cells in patients with psoriasis.

abstract：:The effect of the proteolytic enzyme savinase on human plantar skin in vitro was examined by light and electron microscopy to elucidate the morphological involvement of activated savinase in human epidermis. Light microscopic examination of incubated skin fragments demonstrated that the histological changes produced b...

journal_title：Archives of dermatological research

authors： Imai S

更新日期：1991-01-01 00:00:00

abstract：:Stratum corneum forms the UV barrier. The effect of ultraviolet B (UVB) on normal skin was extensively studied; however, its effect on barrier perturbed skin remains undefined. Both barrier perturbation and UVB irradiation induce endoplasmic reticulum (ER) stress and unfolded protein response (UPR) in keratinocytes. M...

journal_title：Archives of dermatological research

authors： Lee SE,Takagi Y,Nishizaka T,Baek JH,Kim HJ,Lee SH

更新日期：2017-09-01 00:00:00

abstract：:Results of previous investigations have indicated that photochemotherapy (PUVA) attacks membranes of target cells. Using the combination of a stopped-flow technique and laser irradiation we were able to prove that the fast PUVA effect is explainable solely by the membrane damage. Lymphoid cells of healthy persons or p...

journal_title：Archives of dermatological research

authors： Böhm F,Meffert H,Bauer E

更新日期：1986-01-01 00:00:00

abstract：:The histological and ultrastructural effects following 3 weeks' topical treatment with two agents (all-trans retinoic acid and a new synthetic retinoid-like substance, CD271) were evaluated on the epidermis and the epithelial wall of the pseudocomedones in rhino mouse skin. The comedolytic effects of these drugs were ...

journal_title：Archives of dermatological research

authors： Bernerd F,Ortonne JP,Bouclier M,Chatelus A,Hensby C

更新日期：1991-01-01 00:00:00

abstract：:Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects the patients' quality of life greatly often from a very young age. Its worldwide incidence in children and adults varies, but it is usually among the first ten causes of dermatological consultation worldwide. There is a wide variety of treatmen...

journal_title：Archives of dermatological research

authors： de María Díaz Granados L,Quijano MA,Ramírez PA,Aguirre N,Sanclemente G

更新日期：2018-01-01 00:00:00

abstract：:Eleven dysplastic melanocytic naevi with various degrees of dysplasia, as judged by light microscopy, were studied by transmission electron microscopy, and their intra-epidermal melanocytes compared with those of five superficial spreading melanomas and seven common benign naevocellular naevi. Intra-epidermal melanocy...

journal_title：Archives of dermatological research

authors： Langer K,Rappersberger K,Steiner A,Konrad K,Wolff K

更新日期：1990-01-01 00:00:00

abstract：:Botulinum toxin type A (BoNT-A) is an easy and fast treatment for gingival smile (GS). The objective of the study was to compare the reduction of gingival exposure using three different doses of abobotulinumtoxinA (ABO) in patients with different severities of anterior GS, and to assess treatment safety and patients' ...

journal_title：Archives of dermatological research

authors： Hexsel D,Dal'Forno T,Camozzato F,Valente I,Soirefmann M,Silva AF,Siega C

更新日期：2020-07-28 00:00:00

abstract：:Epstein-Barr virus (EBV) can infect epithelial cells as well as B lymphocytes. Infection of the male and female genital tracts has recently been demonstrated, and it has been suggested that the virus may be sexually transmissible. In our study we investigated whether EBV can be found in the anal region of sexually act...

journal_title：Archives of dermatological research

authors： Näher H,Lenhard B,Wilms J,Nickel P

更新日期：1995-01-01 00:00:00

abstract：:Localized scleroderma (LoSc) is rare connective tissue disease that manifests with inflammation and fibrosis of the skin. Depending on the LoSc subtype, adjacent structures such as subcutaneous tissue, fascia, muscles, bones may be affected. The hallmark of fibrosis is tissue remodelling with excess deposition of extr...

journal_title：Archives of dermatological research

authors： Wolska-Gawron K,Bartosińska J,Krasowska D

更新日期：2020-07-01 00:00:00

abstract：:Epidermolytic hyperkeratosis (EH) is a genetic disorder of keratins associated with epidermal differentiation. Affected individuals carry gene mutations for conserved sequences of keratins K1 or K10. The structural alterations of tonofilaments in EH seem to be a direct consequence of the keratin gene mutations. EH epi...

journal_title：Archives of dermatological research

authors： Ishida-Yamamoto A,Iizuka H,Manabe M,O'Guin WM,Hohl D,Kartasova T,Kuroki T,Roop DR,Eady RA

更新日期：1995-01-01 00:00:00

abstract：:Medical innovation is crucial to advancing our field, and physicians have the potential to play a leading role due to their daily patient care experiences. The objective of this study was to evaluate the interest in, and barriers to participating in innovation. Two surveys were conducted; the first cross-sectional sur...

journal_title：Archives of dermatological research

authors： Lee KC,Lee I,Okhovat JP,Ko J,Powers JG,Ellis DL,Cheeley J,Garibyan L

更新日期：2020-08-09 00:00:00

abstract：:Androgenetic alopecia (AGA) is a dermatological disorder of scalp hair loss characterized by a progressive miniaturization of hair follicles with shortened anagen phase leading to a decreased number of hairs on the scalp. It is a complex polygenic trait prevailing around two-thirds of the male population. Elevated exp...

journal_title：Archives of dermatological research

authors： Premanand A,Reena Rajkumari B

更新日期：2018-07-01 00:00:00

abstract：:Organ size regulation is a highly coordinated process involving complex mechanisms. Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif, also known as WWTR1 (TAZ) have recently been linked to organ size determination and cell proliferation. Pilomatrixoma (PM) is a benign tumor of the a...

journal_title：Archives of dermatological research

authors： Cappellesso R,Bellan A,Saraggi D,Salmaso R,Ventura L,Fassina A

更新日期：2015-05-01 00:00:00

abstract：:The case of a 44-year-old man with a primary cutaneous large B-cell non-Hodgkin's lymphoma of the scalp is reported. His mother died of gastric lymphoma and his sib brother is in a 20-year remission of T-cell lymphoma. The patient presented with a 16-year history of occipital and parietal alopecia and a recently worse...

journal_title：Archives of dermatological research

authors： Colovic N,Jurisic V,Terzic T,Atkinson HD,Colovic M

更新日期：2009-10-01 00:00:00

abstract：:Vitiliginous patients undergoing photochemotherapy with TMP were less susceptible to a sun burn. To investigate this point, the MED for UV-B was measured before, 2 h, and 24 h after oral intake of TMP in 10 healthy volunteers. There was an increase of MED when UV exposure had taken place 2 h after TMP intake (P < 0.01...

journal_title：Archives of dermatological research

authors： Agache PG,Coupez L

更新日期：1980-01-01 00:00:00

abstract：:In a previous study, impedance measurements and phoreographic response were shown to quantify significant differences between involved and non-involved skin in psoriasis. The same techniques were used to objectivate the evolution on skin condition on patients treated with dioxyanthranol, difluprednate, and photochemot...

journal_title：Archives of dermatological research

authors： Cambrai M,Clar EJ,Grosshans E,Altermatt C

更新日期：1979-03-31 00:00:00

abstract：:Ionotrope glutamate receptors of the N-methyl-D-aspartate (NMDA) receptor type are expressed on keratinocytes and influence the intracellular calcium concentration. The importance of NMDA receptors in pathophysiological processes in the skin is, however, still unclear. Epidermal distribution patterns of NMDA receptors...

journal_title：Archives of dermatological research

authors： Fischer M,William T,Helmbold P,Wohlrab J,Marsch WCh

更新日期：2004-09-01 00:00:00

abstract：:Atopic dermatitis (AD) can be exacerbated by various factors, including emotional stress, scratching and sweating. The aim of the present study was to evaluate the hypothesis that the inflammatory reaction in AD is also neurogenic. For this purpose, the levels of vasoactive intestinal polypeptide were measured radioim...

journal_title：Archives of dermatological research

authors： Pincelli C,Fantini F,Romualdi P,Lesa G,Giannetti A

更新日期：1991-01-01 00:00:00

abstract：:The exposure of naked unprotected skin to solar radiation may result in numerous acute and chronic undesirable effects. Evidence suggests that silymarin, a standardized extract from Silybum marianum (L.) Gaertn. seeds, and its major component silybin suppress UVB-induced skin damage. Here, we aimed to investigate the ...

journal_title：Archives of dermatological research

authors： Rajnochová Svobodová A,Gabrielová E,Ulrichová J,Zálešák B,Biedermann D,Vostálová J

更新日期：2019-08-01 00:00:00

abstract：:Investigations on the nutrient requirements of Malassezia yeasts led to the preparation of a new minimal medium consisting of an amino nitrogen and a lipid source, which only allowed the growth of the species M. furfur. Carbohydrates, electrolytes, vitamins and trace elements were not required. Using the basal medium,...

journal_title：Archives of dermatological research

authors： Mayser P,Imkampe A,Winkeler M,Papavassilis C

更新日期：1998-05-01 00:00:00

abstract：:Exposure of hairless mice to the light of a germicidal lamp (254 nm) under conditions which are known to induce epidermal DNA synthesis, cell proliferation, and polyamine metabolism produced a marked increase of polyamine excretion in the urine which lasted for many days. The increase was about the same for free and a...

journal_title：Archives of dermatological research

authors： Seiler N,Richards W,Knödgen B

更新日期：1981-01-01 00:00:00

abstract：:Apoptosis is an important cofactor in the pathogenesis of a plethora of malignancies. However, little is known about modulation of the expression of bcl gene family in melanocytic tumors. To determine the role of bcl-2, bcl-x and bax in melanocytic tumors we investigated the differential expression of these genes via ...

journal_title：Archives of dermatological research

authors： Leiter U,Schmid RM,Kaskel P,Peter RU,Krähn G

更新日期：2000-05-01 00:00:00

abstract：:Typical confluent lesions of lichen planus were transplanted onto nude mice and cultured in organ culture. The characteristic histologic appearance of lichen planus disappeared after grafting and became similar to normal skin within 6 weeks on nude mice; the dense lymphocyte infiltrate in dermis disappeared, the basal...

journal_title：Archives of dermatological research

authors： Tammi R,Hyyryläinen A,Fräki JE

更新日期：1988-01-01 00:00:00

abstract：:Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune blistering diseases characterized by a loss of cell-cell adhesion and by autoantibodies directed against epidermal cadherins. PF antigen has been established as desmoglein I which is located strictly on the desmosome, whereas the precise ultrastructur...

journal_title：Archives of dermatological research

authors： Bédane C,Prost C,Thomine E,Intrator L,Joly P,Caux F,Blecker M,Bernard P,Leboutet MJ,Tron F,Lauret P,Bonnetblanc JM,Dubertret L

更新日期：1996-06-01 00:00:00

abstract：:An ultrastructural study of the skin lesion of a young patient affected by pseudo-Kaposi's sarcoma of the Bluefarb-Stewart type (BSS) is reported. The neoplasm consisted of a proliferation of vascular structures mostly consisting of a solid bud of endothelial cells surrounded by a thinned and polystratified basement m...

journal_title：Archives of dermatological research

authors： Fimiani M,Simoni S,Miracco C,De Santi M,Luzi P,Andreassi L

更新日期：1989-01-01 00:00:00

abstract：:Biopsy specimens from mixed connective tissue disease (MCTD) and discoid lupus erythematodes (DLE) skin lesions were stained with monoclonal antibodies to differentiation and activation antigens. In addition, the blast cells were studied by combining autoradiography with immunoperoxidase staining. In both disease cond...

journal_title：Archives of dermatological research

authors： Bergroth V,Konttinen YT,Piirainen H,Johansson E,Nordström D,Malmström M

更新日期：1988-01-01 00:00:00

abstract：:Exposure to a dry environment leads to depletion of water from the peripheral stratum corneum layers in a process dependent on the relative humidity (RH) and the intrinsic properties of the tissue. We hypothesized that by modulating the water content of the stratum corneum in the surface layers, RH effects the rate of...

journal_title：Archives of dermatological research

authors： Watkinson A,Harding C,Moore A,Coan P

更新日期：2001-09-01 00:00:00

abstract：:Histochemical findings of primary and metastatic amelanotic melanomas were shown by the formaldehyde-induced fluorescence method (Falck and Hillarp). All or some of the amelanotic melanoma cells were discovered to emit green specific fluorescence. Results of the determination of 5-S-cysteinyldopa and DOPA in amelanoti...

journal_title：Archives of dermatological research

authors： Morishima T,Tatsumi F,Fukada E,Watanabe M,Nagashima N,Hanawa S

更新日期：1983-01-01 00:00:00

abstract：:Scleroderma is a chronic fibrosing disease, in which an early inflammatory reaction precedes the fibrotic response. Systematic analysis of the pathways involved in the development of the disease together with information derived from novel animal models have helped to better understand the mechanisms that trigger and ...

journal_title：Archives of dermatological research

authors： Eckes B,Hunzelmann N,Moinzadeh P,Krieg T

更新日期：2007-06-01 00:00:00

abstract：:Paraneoplastic pemphigus patients (PNP) develop a group of autoantibodies, among which those against envoplakin and periplakin are almost always found. Epitope mapping has indicated that the linker subdomains of the proteins harbor the major antigenic sites recognized by PNP sera. In order to detect specific autoantib...

journal_title：Archives of dermatological research

authors： Huang Y,Li J,Zhu X

更新日期：2009-10-01 00:00:00