UV-induced changes in urinary polyamine excretion in the mouse.

Abstract:

:Exposure of hairless mice to the light of a germicidal lamp (254 nm) under conditions which are known to induce epidermal DNA synthesis, cell proliferation, and polyamine metabolism produced a marked increase of polyamine excretion in the urine which lasted for many days. The increase was about the same for free and acetylated polyamines. Although the ratio of N1-acetylspermidine/N8-acetylspermidine increased somewhat in the urine of animals exposed to UV, the increase was not significant enough to be useful as a marker of enhanced cell proliferation. A single topical dose of alpha-difluoromethylornithine, a selective inhibitor or ornithine decarboxylase, prevented the UV-induced increase of polyamine excretion in agreement with its effect on UV-induced epidermal polyamine turnover.

journal_name

Arch Dermatol Res

authors

Seiler N,Richards W,Knödgen B

doi

10.1007/BF00417146

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

25-32

issue

1

eissn

0340-3696

issn

1432-069X

journal_volume

270

pub_type

杂志文章
  • [Effect of salicylic acid on the blanching effect of flumethasone pivalate (author's transl)].

    abstract::Test results are reported of the effect of salicylic acid on the vasoconstrictive effect of flumethasone pivalate. In specific, the depigmentation of the skin (identical with increase in lightness of the skin) following topical application of flumethasone pivalate was investigated with the aid of an improved spectroph...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00417384

    authors: Wienert V,Blazek V

    更新日期:1981-01-01 00:00:00

  • Interaction between C1-INA, coagulation, fibrinolysis and kinin system in hereditary angioneurotic edema (HANE) and urticaria.

    abstract::The C1-inactivator plays an important role not only in the initial phases of the complement system, but also in those of the coagulation, fibrinolysis and kinin systems. The present study was concerned with the reciprocal influence of decreased C1-inactivator levels in patients with hereditary angioneurotic edema (HAN...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00413358

    authors: Bork K,Witzke G,Artmann K,Benes P,Böckers M,Kreuz W

    更新日期:1984-01-01 00:00:00

  • Incidence and in-vivo relevance of anti-interferon antibodies during treatment of low-grade cutaneous T-cell lymphomas with interferon alpha-2a combined with acitretin or PUVA.

    abstract::Interferon-alpha combined with retinoid or PUVA is used for the treatment of cutaneous T-cell lymphoma. Anti-IFN-alpha antibodies (IFN ab) occur regularly during IFN-alpha treatment. We investigated the incidence of neutralizing and binding IFN ab and analysed their relationship with clinical and immunological paramet...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF02505252

    authors: Rajan GP,Seifert B,Prümmer O,Joller-Jemelka HI,Burg G,Dummer R

    更新日期:1996-08-01 00:00:00

  • Histamine helps development of eczematous lesions in experimental contact dermatitis in mice.

    abstract::Histamine is released from mast cells in the skin, causing urticaria and itching. However, little is known about the roles of histamine in development of eczematous lesions in contact dermatitis. Effects of histamine on development of eczematous lesions in contact dermatitis were assessed using histamine-deficient mic...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s00403-005-0569-5

    authors: Seike M,Takata T,Ikeda M,Kodama H,Terui T,Ohtsu H

    更新日期:2005-08-01 00:00:00

  • The expression of interleukin-8 receptor in untreated and treated psoriasis.

    abstract::The expression of IL-8 in psoriasis has been clearly shown with the use of immunocytochemical, RT-PCR and in situ hybridization methods. The presence of its ligand, the IL-8 receptor, has been demonstrated by the RT-PCR technique. We report here a study of the expression of both IL-8 type A and B receptors by immunohi...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s004030050218

    authors: Beljaards RC,Van Beek P,Nieboer C,Stoof TJ,Boorsma DM

    更新日期:1997-07-01 00:00:00

  • Visualization and characterization of UVB-induced reactive oxygen species in a human skin equivalent model.

    abstract::Reactive oxygen species (ROS) play important roles in the process of ultraviolet-induced skin damage or photoaging. Although many enzymatic and chemical methods have been developed for evaluating ROS, evaluation methods for ROS generation in living systems are quite limited. Here we propose a unique system to visualiz...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s00403-007-0804-3

    authors: Hakozaki T,Date A,Yoshii T,Toyokuni S,Yasui H,Sakurai H

    更新日期:2008-04-01 00:00:00

  • Transient immune deposits in the papillary dermis and in the epidermis. A light-microscopical study on the experimental Arthus reaction.

    abstract::To have as further insight into the localizations of immune deposits in the skin the reversed passive and the passive Arthus reactions were carried out in the foot-pads skin of guinea-pigs using horseradish peroxidase as antigen. The transient localizations of immune deposits in the papillary dermis and in the epiderm...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00404457

    authors: Ueki H,Nakaye M,Masuda T

    更新日期:1980-01-01 00:00:00

  • Flushing in rosacea: a possible mechanism.

    abstract::Flushing in rosacea has been investigated by means of (a) pharmacological inhibition of some possible chemical mediators and (b) titration of bradykinin as a possible effector directly in the blood. Clonidine-inhibited flushing was seen in all patients (mean 45%), other drugs had poorer results. Bradykinin increased i...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00509061

    authors: Guarrera M,Parodi A,Cipriani C,Divano C,Rebora A

    更新日期:1982-01-01 00:00:00

  • Molecular and cellular mechanisms of bone morphogenetic proteins and activins in the skin: potential benefits for wound healing.

    abstract::Bone morphogenetic proteins (BMPs) and activins are phylogenetically conserved proteins, belonging to the transforming growth factor-β superfamily, that signal through the phosphorylation of receptor-regulated Smad proteins, activating different cell responses. They are involved in various steps of skin morphogenesis ...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章,评审

    doi:10.1007/s00403-013-1381-2

    authors: Moura J,da Silva L,Cruz MT,Carvalho E

    更新日期:2013-09-01 00:00:00

  • Growth requirements and nitrogen metabolism of Malassezia furfur.

    abstract::Investigations on the nutrient requirements of Malassezia yeasts led to the preparation of a new minimal medium consisting of an amino nitrogen and a lipid source, which only allowed the growth of the species M. furfur. Carbohydrates, electrolytes, vitamins and trace elements were not required. Using the basal medium,...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s004030050304

    authors: Mayser P,Imkampe A,Winkeler M,Papavassilis C

    更新日期:1998-05-01 00:00:00

  • Cryotherapy plus low-dose oral isotretinoin vs cryotherapy only for the treatment of anogenital warts: a randomized clinical trial.

    abstract:BACKGROUND:Anogenital warts are a common human papillomavirus infection. They cause emotional distress, especially when they are in the anogenital region. Cryotherapy is a first-line treatment. Previous clinical trials and case series have reported variable results with retinoids (isotretinoin) as adjuvant therapy. OB...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s00403-020-02182-y

    authors: Reyna-Rodríguez IL,Chavez-Alvarez S,Garza-Rodríguez V,Franco-Marquez R,Gonzalez-Martinez G,Ocampo-Candiani J,Villarreal-Martinez A

    更新日期:2021-01-12 00:00:00

  • Expression of EGF receptor, involucrin, and cytokeratins in basal cell carcinomas and squamous cell carcinomas of the skin.

    abstract::The distribution of several markers of keratinocyte differentiation was studied in normal epidermis, basal cell carcinomas (BCCs), and squamous cell carcinomas (SCCs) using the immunoperoxidase technique on frozen sections of punch biopsy specimens. As markers a panel of chain-specific monoclonal antibodies (MoAbs) di...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00426583

    authors: Lavrijsen AP,Tieben LM,Ponec M,van der Schroeff JG,van Muijen GN

    更新日期:1989-01-01 00:00:00

  • Leakage of sweat into the dermo-epidermal junction as a possible trigger for lichen planus lesion development.

    abstract::No previous studies have convincingly linked sweating disturbance with the subsequent development of lichen planus (LP). Therefore, we investigated whether sweating disturbance could be specifically detected in LP lesions and how it could trigger lesion development. We utilized the impression mold technique (IMT), whi...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s00403-018-1882-0

    authors: Mizukawa Y,Yamazaki Y,Shiohara T

    更新日期:2019-01-01 00:00:00

  • Ultrastructural aspects of normolipidemic xanthomatosis.

    abstract::Electron microscopic aspects in ten cases of normolipidemic cutaneous xanthomatosis have been investigated. Two additional types IV and V hyperlipoproteinaemic xanthomatosis have also been included. Ultrastructural findings in all cases were similar. Abundant histiocytic cells with numerous intracytoplasmic lipid vacu...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00694624

    authors: Ferrando J,Bombi JA

    更新日期:1979-10-01 00:00:00

  • Secretory component (polymeric immunoglobulin receptor) as an intrinsic inhibitor of biological functions of interferon gamma in keratinocytes.

    abstract::Secretory component (SC) acts as a transmembrane polymeric immunoglobulin receptor of epithelial cells and is known to bind to polymeric IgA and to contribute to the secretion of secretory IgA (sIgA). We describe a new biological function for free SC (FSC) by which the expression of intercellular adhesion molecule-1 (...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00374074

    authors: Nihei Y,Maruyama K,Zhang JZ,Kobayashi K,Kaneko F

    更新日期:1995-01-01 00:00:00

  • Mortality and risk factors among Israeli bullous pemphigoid patients.

    abstract::There are differences concerning reported mortality rates and prognostic factors of bullous pemphigoid (BP) patients in different studies. Our objectives were to evaluate the mortality rates and prognostic factors among Israeli BP patients compared to matched control subjects. Three age- and sex-matched patients witho...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s00403-018-1875-z

    authors: Rozenblat M,Halaj A,Rozenblat T,Fisher S,Sah M,Dodiuk-Gad RP,Ziv M

    更新日期:2019-01-01 00:00:00

  • Expression of lung resistance protein in epithelioid sarcoma in vitro and in vivo.

    abstract::The incidence of epithelioid sarcoma among patients with malignant soft tissue tumors is small, but the rates of recurrence and metastasis of this type of sarcoma are high. To date, effective chemotherapy for advanced epithelioid sarcoma has not been established and, furthermore, epithelioid sarcoma is known to exhibi...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s004030000127

    authors: Kusakabe H,Iwasaki H,Sano K,Kiyokane K

    更新日期:2000-06-01 00:00:00

  • Purification of rat cutaneous mast cells with Percoll density centrifugation.

    abstract::The skin is the major site on anaphylaxis, and cutaneous mast cells have an important role in its reactions. The isolation and purification of rat cutaneous mast cells are described here. Rat abdominal skin was digested with collagenase and hyaluronidase, and centrifuged with Percoll. The buoyant density of cutaneous ...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00426614

    authors: Hachisuka H,Kusuhara M,Higuchi M,Okubo K,Sasai Y

    更新日期:1988-01-01 00:00:00

  • High incidence of primary melanomas in an MC1R RHC homozygote/CDKN2A mutant genotype patient.

    abstract::Melanoma incidence in Australia remains the highest in the world; hence understanding its causation is paramount for future therapeutic developments. Multiple primary melanomas are also common occurrences among the Australian population with identified risk factors such as personal and family history of melanoma, fair...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s00403-015-1582-y

    authors: Sinnya S,Jagirdar K,De'Ambrosis B,McMeniman E,Sturm RA,Soyer HP

    更新日期:2015-10-01 00:00:00

  • Effect of theophylline on the transport of tyrosine in cultured B-16 mouse melanoma cells.

    abstract::The effect of theophylline, an inhibitor of phosphodiesterase, on tyrosine (Tyr) transport across cell membrane was studied using cultured B-16 mouse melanoma cells. 1.5 mM Theophylline in culture medium increased Tyr uptake velocity in linear fashion up to 36 h, after which it reached a plateau at which the cells sho...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00414014

    authors: Saga K,Shimojo T

    更新日期:1984-01-01 00:00:00

  • Induction and repair of UVB-induced cyclobutane pyrimidine dimers and (6-4) photoproducts in organ-cultured normal human skin.

    abstract::To examine the induction and repair of UV-induced DNA damage, indirect immunofluorescence was performed on UVB-irradiated organ-cultured normal human skin using monoclonal antibodies specific for either cyclobutane pyrimidine dimers or (6-4) photoproducts. Nuclear immunofluorescence of cyclobutane pyrimidine dimers an...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00375800

    authors: Muramatsu T,Kobayashi N,Tada H,Yamaji M,Shirai T,Mori T,Ohnishi T

    更新日期:1992-01-01 00:00:00

  • Polymorphonuclear granulocyte chemotaxis and chemotactic factor generation by concanavalin A-stimulated peripheral blood mononuclear cells in patients with psoriasis.

    abstract::Polymorphonuclear leukocytes from patients with psoriasis demonstrated a significantly enhanced chemotactic responsiveness to zymosan-activated human serum as compared to granulocytes from healthy volunteers. Furthermore, psoriatic peripheral blood mononuclear cells stimulated with concanavalin a produced an increased...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00409454

    authors: Csató M,Dobozy A,Hunyadi J,Kenderessy SA,Simon N

    更新日期:1981-01-01 00:00:00

  • Known HPV types have no association with keratoacanthomas.

    abstract::Certain HPV types have been linked to the genesis and development of premalignant and malignant skin diseases. There have been several contradictory reports on the role of HPV infections in the development of keratoacanthomas (KAs). To further study the involvement of HPVs in the aetiology of KAs, we investigated para...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF02505821

    authors: Lu S,Syrjänen SL,Havu VK,Syrjänen S

    更新日期:1996-03-01 00:00:00

  • Pathologic S-phase in the cells of eccrine sweat glands and of hair follicles in psoriasis.

    abstract::The prolongation of the S-phase, characteristic of psoriatic keratinocytes, can be observed in cells of the eccrine sweat glands as well as in those of the infundibular part of hair follicles. In healthy individuals the average duration of DNA-synthesis time (ts) in the cells of the hair follicle is 6.8 h, in unaffect...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00404286

    authors: Galosi A,Pullmann H,Steigleder GK

    更新日期:1980-01-01 00:00:00

  • Role of androgens in female-pattern androgenetic alopecia, either alone or associated with other symptoms of hyperandrogenism.

    abstract::The roles of androgen hypersecretion, in situ enzyme activity, and androgen receptors in androgenetic alopecia in women are still a matter of debate. We studied 187 women with alopecia, which we graded I, II, or III, according to Ludwig's classification, and 21 healthy control women. All participants were subjected to...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s004030000184

    authors: Vexiau P,Chaspoux C,Boudou P,Fiet J,Abramovici Y,Rueda MJ,Hardy N,Reygagne P

    更新日期:2000-12-01 00:00:00

  • Studies on amelanotic melanoma with the fluorescence method (Falck and Hillarp) and biochemical analysis of 5-S-cysteinyldopa in the tissues.

    abstract::Histochemical findings of primary and metastatic amelanotic melanomas were shown by the formaldehyde-induced fluorescence method (Falck and Hillarp). All or some of the amelanotic melanoma cells were discovered to emit green specific fluorescence. Results of the determination of 5-S-cysteinyldopa and DOPA in amelanoti...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00417207

    authors: Morishima T,Tatsumi F,Fukada E,Watanabe M,Nagashima N,Hanawa S

    更新日期:1983-01-01 00:00:00

  • Effects of combination of mizolastine and proteoglycan on chronic urticaria: a randomized controlled trial.

    abstract::The present study aimed to observe the therapeutic effect of combined mizolastine and proteoglycan in chronic urticaria. The patients were randomly divided into the treatment group (n = 56) and the control group (n = 44). The treatment group was medicated with calcium gluconate (10 mg/ time, 1 time/day), vitamin D3 (i...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00403-019-01967-0

    authors: Xiong X,Song L,Chen F,Ma X

    更新日期:2019-12-01 00:00:00

  • The effect of nitrogen plasma on the skin and hair follicles: a possible promising future for the treatment of alopecia.

    abstract::Nowadays, there is a great attention to the plasma applications in medicine. Not only does cold atmospheric pressure plasma provide a therapeutic opportunity to control redox-based processes, it is also an innovative method in rejuvenation. Given the current interest in new methods of rejuvenation, we aimed to introdu...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/s00403-019-02020-w

    authors: Babossalam S,Abdollahimajd F,Aghighi M,Mahdikia H,Dilmaghanian A,Toossi P,Shokri B

    更新日期:2020-07-01 00:00:00

  • Modulation of type-IV procollagen and laminin production in A431 human squamous epidermoid carcinoma cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) and epidermal growth factor (EGF).

    abstract::The effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) and epidermal growth factor (EGF) on type-IV-procollagen (basement-membrane collagen) and laminin synthesis, turnover, and secretion was studied in human A431 squamous epidermoid carcinoma cells. Type-IV procollagen and laminin were biochemically and immunologic...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF00509237

    authors: Panneerselvam M,Sahai A,Salomon DS

    更新日期:1985-01-01 00:00:00

  • Tumour necrosis factors and several interleukins inhibit the growth and modulate the antigen expression of normal human melanocytes in vitro.

    abstract::In the present study the action of various cytokines as regulators of human melanocyte growth and differentiation was examined in vitro. Primary melanocyte cultures were obtained in complete medium free of 12-O-tetradecanoylphorbol-13-acetate or serum. First passage melanocytes were treated with various concentrations...

    journal_title:Archives of dermatological research

    pub_type: 杂志文章

    doi:10.1007/BF01105076

    authors: Krasagakis K,Garbe C,Eberle J,Orfanos CE

    更新日期:1995-01-01 00:00:00