Abstract:
:The initiator of calculus matrix calcification, in vitro, was isolated. Crude phospholipid, known to contain the factor, was separated into five fractions by column chromatography. A single protein-containing fraction induced apatite formation during incubation. The nucleating fraction was indentified as a proteolipid.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Ennever J,Vocel JJ,Riggan LJ,Paloski SBdoi
10.1177/00220345770560020701subject
Has Abstractpub_date
1977-02-01 00:00:00pages
140-2issue
2eissn
0022-0345issn
1544-0591journal_volume
56pub_type
历史文章,杂志文章abstract::TWIST1 plays a crucial role in dentinogenesis, and its activity depends on both a dimerization partner selection and phosphorylation. Other factors, like Id proteins, can affect the availability of dimerization partners for TWIST1, subsequently leading to diverse biological outcomes. The purpose of this study was to e...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514530164
更新日期:2014-06-01 00:00:00
abstract::The effects of Escherichia coli endotoxin upon mouse L929 cell proliferation, DNA synthesis, protein synthesis, and proline incorporation were determined. It was found that a level of endotoxin which inhibited cell proliferation prompted a similar inhibition of DNA synthesis and overall cell protein synthesis. In cont...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580061301
更新日期:1979-06-01 00:00:00
abstract::An in vitro model has been developed for measurement of initial attachment of 3H-labeled human gingival fibroblasts (HGF) and periodontal ligament cells (HPDL cells) to sieved dentin powder. Reproducible attachment was obtained and was closely related to the number of plated cells, the amount of dentin powder, the tem...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720030901
更新日期:1993-03-01 00:00:00
abstract:UNLABELLED:We have previously shown that the resin monomer 2-hydroxyethylmethacrylate (HEMA) affects mouse B-lymphocyte activity, leading to increased IgG1 antibody production in vivo. In the present study, we tested, in vitro, the hypothesis that HEMA also affects human B-lymphocyte activity. The in vitro production o...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510378522
更新日期:2010-12-01 00:00:00
abstract::The purpose of this investigation was to examine the inhibitory effects of aqueous extracts derived from the bark-containing sticks (Neem stick) of Azadirachta indica upon bacterial aggregation, growth, adhesion to hydroxyapatite, and production of insoluble glucan, which may affect in vitro plaque formation. Neem sti...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750021301
更新日期:1996-02-01 00:00:00
abstract::Solder microstructures were found to be influenced by those of the castings. A tendency of solder to match the microstructures contacted during its solidification was demonstrated. Several different types of defects were identified in the soldered joints. Tentative correlations of the observed microstructures and defe...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580031401
更新日期:1979-03-01 00:00:00
abstract::Mutations in ALPL result in hypophosphatasia (HPP), a disease causing defective skeletal mineralization. ALPL encodes tissue nonspecific alkaline phosphatase (ALP), an enzyme that promotes mineralization by reducing inorganic pyrophosphate, a mineralization inhibitor. In addition to skeletal defects, HPP causes dental...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515573273
更新日期:2015-05-01 00:00:00
abstract::Autonomic and behavioral responses to seven dental procedures were studied in 21 pedodontic patients aged six to 12. When mean pulse rate, pulse amplitude, absolute skin conductance, and skin-conductance responses were compared over all subjects, the injection of the local anesthetic consistently elicited the greatest...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620060801
更新日期:1983-06-01 00:00:00
abstract::Thermal and mechanical hypersensitivity in the injured region is a common complication. Although it is well known clinically that thermal and mechanical sensitivity of the oral mucosa is different from that of the skin, the mechanisms underlying injured pain of the oral mucosa remain poorly understood. The transient r...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514565645
更新日期:2015-03-01 00:00:00
abstract::This study investigated the relevance between pulp vitality and autophagy in aged human dental pulp cells (HDPCs) and whether peroxisome proliferator-activated receptor gamma (PPARγ) affects autophagy regulation for homeostasis in the aging progress. In vivo experiments were used in human and Sprague-Dawley rat teeth ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515573833
更新日期:2015-05-01 00:00:00
abstract::The dimensional accuracy of porcelain fused to metal crown and bridge castings was determined on truncated cone-shaped steel dies. Ni-Cr castings produced in manufacturers' laboratories were consistently undersize, while precious metal castings were consistently oversize. Ni-Cr castings, produced in NBS laboratories u...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580120501
更新日期:1979-12-01 00:00:00
abstract::The regulation of blood flow of the dental pulp was investigated in dogs and rats anesthetized with sodium pentobarbital. Pulpal blood flow was altered by variations of local and systemic hemodynamics. Variation in pulpal hemodynamics was attained by means of close intra-arterial injections of adrenergic agonists (NE ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/002203458506400415
更新日期:1985-04-01 00:00:00
abstract::Pieces of fresh rat incisor enamel were extracted with various buffer solutions and prepared for electron microscopy. I observed partial or complete removal of organic constituents, shrinkage of rods and interrods, separation of stippled material from the enamel, and partial decalcification. The results modify the con...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:1982-12-01 00:00:00
abstract::Periodontitis is a complex, multifactorial chronic disease involving continuous interactions among bacteria, host immune/inflammatory responses, and modifying genetic and environmental factors. More than any other cytokine family, the interleukin (IL)-1 family includes key signaling molecules that trigger and perpetua...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520945209
更新日期:2020-12-01 00:00:00
abstract::The periodontium contains heterogeneous mesenchymal cell populations with various differentiation potentials. The capacity of these cells for tissue formation as well as the origin of their precursors are still not entirely defined. In this study, cells originating from different periodontal tissues were cultured in v...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345950740051201
更新日期:1995-05-01 00:00:00
abstract::Studies on mechanisms underlying the differentiation of dental pulp stem cells are critical for the understanding of the biology of odontogenesis and for dental tissue engineering. Here, we tested the hypothesis that stem cells from exfoliated deciduous teeth (SHED) differentiate into functional odontoblasts and endot...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510368647
更新日期:2010-08-01 00:00:00
abstract::Decisions to replace existing restorations are often based on clinical findings of margin discrepancies and other restoration defects. Previous studies have suggested that such findings do not correlate well with the actual presence of secondary caries, and that treatment should be deferred until caries is clinically ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720121301
更新日期:1993-12-01 00:00:00
abstract::The object of the present study was an attempt to relate fluoride concentration in enamel, caries experience, and the degree of fluorosis in a community residing in an area with a high level of fluoride. A significant difference was found between the male and female samples for the F and D parameters. A positive corre...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550012001
更新日期:1976-01-01 00:00:00
abstract::PAX9 is a transcription factor expressed in the tooth mesenchyme during tooth morphogenesis. In Pax9-null mice, tooth development is arrested at the bud stage. In humans, heterozygous mutations in PAX9 have been associated with non-syndromic tooth agenesis, predominantly in the molars. Here, we report 2 novel mutation...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513519801
更新日期:2014-03-01 00:00:00
abstract::Mechanosensitive osteocytes are essential for bone remodeling. Nitric oxide, an important regulator of bone remodeling, is produced by osteocytes through the activity of constitutive endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). We hypothesized that these enzymes regulate the tiss...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034508330861
更新日期:2009-03-01 00:00:00
abstract::Mercury emitted from dental amalgam may select for increased numbers of antibiotic- or mercury-resistant commensal bacteria in patients and increase their risk for bacterial diseases that are resistant to common therapies. We hypothesized that the presence of dental amalgams would increase the level of mercury-, tetra...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/154405910808700502
更新日期:2008-05-01 00:00:00
abstract::The proton probe has been used to map F concentration changes in the enamel of 15 teeth showing clinical evidence of caries. Thin sections through the lesions were microradiographed and measurements made of the surface zone (radiodense) and body (radiolucent) areas. Each section was then scanned with a focused beam of...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345950740111001
更新日期:1995-11-01 00:00:00
abstract::Once established, early-colonizing bacterial species tend to persist in the mouth. To obtain detailed information on the population dynamics of early-colonizing oral anaerobes, we examined the clonal diversity and persistence of clones among oral Fusobacterium nucleatum populations during the first 2 yrs of life. Cons...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910408300613
更新日期:2004-06-01 00:00:00
abstract::Although dental amalgam is used frequently under artificial crowns for restoration of severely damaged teeth, there is little information available on the bond between luting cements and this alloy. This study was designed for determination of the strength of the bond between a dental amalgam alloy and three crown-lut...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345890680111501
更新日期:1989-11-01 00:00:00
abstract::Although systemic bone loss accompanying estrogen deficiency has been proposed as a risk factor for periodontal disease in post-menopausal women, the mechanisms involved remain unclear. The objective of this study was to elucidate the potential bone-sparing effect of estrogen (17beta-estradiol, E(2)) via modulation of...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700214
更新日期:2008-02-01 00:00:00
abstract::Carbamide peroxide (CP) is widely used as a tooth-whitening agent in self-administered tooth-bleaching products. In this study, the effects of 5% and 10% CP on dentinal collagen structure and chemical properties were evaluated in vitro. Thirty-five intact teeth were exposed to 2 whitening protocols (2 or 4 h daily) wi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034518822826
更新日期:2019-04-01 00:00:00
abstract::As a major intracellular degradation and recycling machinery, autophagy plays an important role in maintaining cellular homeostasis and remodeling during normal development. Our previous study showed that fluorapatite (FA) crystal-coated electrospun polycaprolactone (PCL) was capable of inducing differentiation and mi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516636852
更新日期:2016-06-01 00:00:00
abstract::Proteolytic hydrolysis of casein and porcine or bovine glycoproteins by S mutans was demonstrated in the present study. Caseinolytic activity was found in both the soluble contents of the cells and the cellular debris after rupture of the cells. However, caseinolytic activity could not be demonstrated after growth in ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550031701
更新日期:1976-05-01 00:00:00
abstract::Acidic proline-rich proteins were localized histologically by means of the indirect immunoperoxidase technique in the acinar cells of parotid and submandibular gland sections of both man and Macaca fascicularis. These proteins were also identified as constituents of the long term in vivo-formed acquired pellicle on hu...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590081201
更新日期:1980-08-01 00:00:00
abstract::Microducers and modified cephalometric roentgenogram techniques were used to study maximum biting forces and moments in an adult male. The force at the second molar was approximately 10% greater than that at the first molar. At the second molar, the moment of force was approximately 15% less than its value at the firs...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345750540010401
更新日期:1975-01-01 00:00:00