Abstract：
:Proteolytic hydrolysis of casein and porcine or bovine glycoproteins by S mutans was demonstrated in the present study. Caseinolytic activity was found in both the soluble contents of the cells and the cellular debris after rupture of the cells. However, caseinolytic activity could not be demonstrated after growth in the culture fluid from any of the strains of S mutans tested. The soluble fractions of S mutans did not possess glycoprotein hydrolase activity toward porcine or bovine glycoprotein, but glycoprotein hydrolase activity was present in both the cell-debris preparation from cells and in the culture fluid after growth of the cultures. Based on these observations, S mutans may possess several different types of proteinase enzymes with differing specificities for protein substrates.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Cowman RA,Perrella MM,Fitzgerald RJdoi
10.1177/00220345760550031701keywords:
subject
Has Abstractpub_date
1976-05-01 00:00:00pages
391-9issue
3eissn
0022-0345issn
1544-0591journal_volume
55pub_type
杂志文章abstract：:A dental appointment commonly prompts fear of a painful experience, yet we have never fully understood how our brains react to the expectation of imminent tooth pain once in a dental chair. In our study, 21 patients with hypersensitive teeth were tested using nonpainful and painful stimuli in a clinical setting. Subje...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515581642
更新日期：2015-07-01 00:00:00
abstract：:Dental composites develop residual stresses during polymerization due to shrinkage. These stresses may change with time because of relaxation and water sorption in the oral environment. This phenomenon is likely dependent on the composition of the materials, specifically their hydrophilic characteristics, and could re...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513513905
更新日期：2014-02-01 00:00:00
abstract：:The clearance of glucose from saliva was compared with that from spaces located in an intra-oral appliance. The spaces (N = 8) were similar in shape and size to posterior interdental spaces and could be sampled with a microsyringe without removing the appliance from the mouth. The subjects (N = 5) rinsed their mouths ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345850640030301
更新日期：1985-03-01 00:00:00
abstract：:The lack of a reliable bond test has hindered the elucidation of the mechanism for porcelain-metal bonding in dental systems, because a test capable of detecting differences among porcelain-metal bonds of various qualities is required before the reasons for these differences may be ascertained. A method was developed ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345880670020801
更新日期：1988-02-01 00:00:00
abstract：:Eighteen different Streptococcus strains including S mutans, sanguis, mitis, salivarius, bovis, and 2F2, were assayed for their relative adsorption to synthetic hydroxyapatite and for quantities of lactic acid produced while in the adsorbed state. The results indicated that all S mutans and some S sanguis have an enha...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560101401
更新日期：1977-10-01 00:00:00
abstract：:The uptake patterns of 90Sr in developing rat molar enamel were studied in vivo and in vitro. Autoradiographic methods were used that preclude loss or translocation of tracers associated with water-soluble compounds in the sections. In eight-day-old rats injected with the tracer, 90Sr uptake in the enamel was signific...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345800590121301
更新日期：1980-12-01 00:00:00
abstract：:Early childhood caries (ECC) is a chronic disease affecting the oral health of children globally. This disease is multifactorial, but a primary factor is cariogenic microorganisms such as Streptococcus mutans. Biosynthetic gene clusters (BGCs) encode small molecules with diverse biological activities that influence th...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520914519
更新日期：2020-07-01 00:00:00
abstract：:The expired air of a group of 48 persons, 40 with and eight without dental amalgam restorations, was analyzed for its mercury content before and after chewing. Expired air samples were collected in polyethylene bags, and a known quantity of each was pumped into the mercury detector for measurement. The results showed ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345810600090601
更新日期：1981-09-01 00:00:00
abstract：:Although it has been shown that patients are more satisfied with prostheses supported by implants than with conventional dentures, there have been few direct comparisons of the various designs of implant-supported prostheses. This within-subject crossover clinical trial was designed to compare two forms of removable p...
journal_title：Journal of dental research
pub_type： 临床试验,杂志文章
doi：10.1177/00220345970760100901
更新日期：1997-10-01 00:00:00
abstract：:Data from the actual private practices of two dentists were compared with respective data from the participation of the same two dentists in a laboratory model of private practice conducted in the University of North Carolina Dental Research Center. The findings show that a laboratory model can be established which ac...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345750540032501
更新日期：1975-05-01 00:00:00
abstract：:The aim of this study was to test the hypothesis that the chewing of xylitol- or xylitol/sorbitol-containing chewing gum reduces plaque formation and the acidogenic potential of dental plaque. Thirty healthy volunteers aged from 19 to 28 yrs were randomly allocated to one of three test groups, chewing either xylitol-,...
journal_title：Journal of dental research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1177/00220345980770071001
更新日期：1998-07-01 00:00:00
abstract：:Submandibular glands from young adult and aged male and female rats have been examined and various descriptive parameters obtained. Several sex differences were observed with tissue from young and old animals. Sex differences were found in the gland contents of DNA, protein, and sialic acid and in some protein compone...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345810600051501
更新日期：1981-05-01 00:00:00
abstract：:Dental pulp regeneration therapy for the pulpless tooth has attracted recent attention, and clinical trial studies are underway with the tissue engineering approach. However, there remain many concerns, including the extended period for regenerating the dental pulp. In addition, the use of scaffolds increases the risk...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034518772260
更新日期：2018-09-01 00:00:00
abstract：:Tooth enamel is the most highly mineralized tissue in vertebrates. Enamel crystal formation and elongation should be well controlled to achieve an exceptional hardness and a compact microstructure. Enamel matrix calcification occurs with several matrix proteins, such as amelogenin, enamelin, and ameloblastin. Among th...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034514547272
更新日期：2014-10-01 00:00:00
abstract：:Insulin resistance is one of the critical pathogeneses of type 2 diabetes mellitus (T2DM). Elevated levels of plasma branched-chain amino acids (BCAAs) are associated with insulin resistance. Recent studies have demonstrated the role of Porphyromonas gingivalis in the development of insulin resistance. However, the me...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520911037
更新日期：2020-07-01 00:00:00
abstract：:In the past two decades, accumulated evidence has clearly demonstrated the inhibitory effects of laser irradiation on enamel demineralization, but the exact mechanisms of these effects remain unclear. The purpose of this study was to investigate the effects of low-energy CO2 laser irradiation on demineralization of bo...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345000790091401
更新日期：2000-09-01 00:00:00
abstract：:An in vitro model has been developed for measurement of initial attachment of 3H-labeled human gingival fibroblasts (HGF) and periodontal ligament cells (HPDL cells) to sieved dentin powder. Reproducible attachment was obtained and was closely related to the number of plated cells, the amount of dentin powder, the tem...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720030901
更新日期：1993-03-01 00:00:00
abstract：:The reaction of the microvasculature in the periodontal ligament to mechanical pressure is considered a very important phenomenon with respect to the biological background to orthodontic tooth movement. For clarification of the microvascular reaction to mechanical pressure, an experimental model that incorporated a ha...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345920710060701
更新日期：1992-06-01 00:00:00
abstract：:Temperature elevations were measured in the pulp chamber of full cast crown preparations during impression taking with modelling compound in copper bands. Uncontrolled flaming, controlled flaming, and water heating of the bands produced temperatures of 53, 44, and 41.5 C, respectively. The time involved in restoring t...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
abstract：:Secondary palatogenesis occurs when the bilateral palatal shelves (PS), arising from maxillary prominences, fuse at the midline, forming the hard and soft palate. This embryonic phenomenon involves a complex array of morphogenetic events that require coordinated proliferation, apoptosis, migration, and adhesion in the...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034517726284
更新日期：2017-10-01 00:00:00
abstract：:This case-control study evaluated the association of headache and other co-morbid pain with temporomandibular disorder (TMD) pain in adolescents and explored the temporal co-variance of headache and TMD pain. In a population-based sample of 12- to 19-year-olds, 350 patients with self-reported TMD pain and 350 healthy ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513496255
更新日期：2013-09-01 00:00:00
abstract：:Porcine dentin sialophosphoprotein (DSPP) is the most abundant non-collagenous protein in dentin. It is processed by proteases into 3 independent proteins: dentin sialoprotein (DSP), dentin glycoprotein (DGP), and dentin phosphoprotein (DPP). We fractionated DPP and DSP along with TGF-β activity by ion exchange (IE) c...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034514534690
更新日期：2014-07-01 00:00:00
abstract：:One of the main goals of bone tissue engineering is to identify and develop new biomaterials and scaffolds for structural support and controlled cell growth, which allow for formation or replacement of bone tissue. Recently, carbon nanotubes (CNT) have emerged as a potential candidate for bone tissue engineering. CNT ...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034513490957
更新日期：2013-07-01 00:00:00
abstract：:Debonding rates of 164 resin-bonded prostheses (RBP) placed from 1974 to 1985 were examined at recall. The yearly debond rates were calculated, the cumulative probability of failure was determined for the debonded RBPs, and Weibull distribution parameters were determined. For perforated prostheses, there was a high in...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720081401
更新日期：1993-08-01 00:00:00
abstract：:Occlusal alterations may result in changes in the functional performance of masticatory muscles. In this study, we set up an experimental model in rats to examine whether masticatory muscle abnormalities occur after a malocclusion is induced. Rats underwent unilateral amputation of the molar cusps to simulate an occlu...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345990780111101
更新日期：1999-11-01 00:00:00
abstract：:Conservative techniques for improving the appearance of discolored teeth have become popular in the past decade. These include: in-office bleaching with 30% hydrogen peroxide, which is applied on etched enamel with a gauze pad and then exposed to a bleaching light; home bleaching with a mild form of peroxide, such as ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720011001
更新日期：1993-01-01 00:00:00
abstract：:Adhesive bonding of resins to dentin surfaces requires the removal of the layer of debris caused by the cutting. Certain isotonic acidic solutions can do this rapidly. Five solutions were evaluated using cell cultures and pulp studies in monkeys. At concentrations above 10%, each solution caused the cultured human epi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345820610081001
更新日期：1982-08-01 00:00:00
abstract：:Deciduous teeth were collected from children who received professional prophylaxis with an acidulated phosphate-fluoride (APF) or placebo paste and were analyzed to determine fluoride uptake. Enamel fluoride level was increased by the APF paste approximately 300 ppm at a depth of 2.5 micrometers during the first month...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345760550064901
更新日期：1976-11-01 00:00:00
abstract：:Two independent cross-over studies investigated the possibility of enhanced early enamel lesion remineralization with the use of chewing gum. The first study involved a sorbitol-containing chewing gum, and the second, which had an identical protocol, tested a sucrose-containing chewing gum. In each study, 12 volunteer...
journal_title：Journal of dental research
pub_type： 临床试验,杂志文章
doi：10.1177/00220345920710120801
更新日期：1992-12-01 00:00:00
abstract：:Bone marrow-derived mesenchymal stem/progenitor cells (BMSCs) are commonly used in regeneration therapy. The current primary source of BMSCs is the iliac crest; however, the procedure is associated with various burdens on the patient, including the risk of pain and infection. Hence, the possibility to collect BMSCs fr...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034514549377
更新日期：2014-11-01 00:00:00
