Abstract：
:The clearance of glucose from saliva was compared with that from spaces located in an intra-oral appliance. The spaces (N = 8) were similar in shape and size to posterior interdental spaces and could be sampled with a microsyringe without removing the appliance from the mouth. The subjects (N = 5) rinsed their mouths with solutions of 5, 10, or 25% glucose. Samples were obtained from a pair of spaces and from saliva at standard intervals and were analyzed for glucose. The rate of glucose clearance was consistently slower from the spaces than from bulk saliva, as shown by higher concentrations and longer clearance times for the spaces. The clearance curves were similar in shape and were rectilinear when the logarithms of the concentrations were plotted against time. The rate of clearance from the spaces appears to be characteristic for an individual, as was also true of salivary clearance.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Goulet D,Brudevold F,Tehrani A,Attarzadeh Fdoi
10.1177/00220345850640030301subject
Has Abstractpub_date
1985-03-01 00:00:00pages
411-5issue
3eissn
0022-0345issn
1544-0591journal_volume
64pub_type
杂志文章abstract：:The size of a bolus determines how it will be manipulated in the mouth and swallowed. We hypothesized that mucosal sensitivity would be important for masticatory function. The accuracy of solid object size perception, spatial acuity, and food particle size reduction during mastication were measured in 22 healthy adult...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910408300507
更新日期：2004-05-01 00:00:00
abstract：:Calcitonin gene-related peptide (CGRP) plays a crucial role in the modulation of orofacial pain, and we hypothesized that CGRP mediated a neuron-glia crosstalk in orofacial pain. The objective of this study was to elucidate the mechanisms whereby CGRP mediated trigeminal neuron-glia crosstalk in modulating orofacial p...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520950296
更新日期：2021-01-01 00:00:00
abstract：:Damage to the dentin matrix investigates the proliferation and mobilization of dental progenitor cells to the injury site, the mechanisms of which are not defined. EphB receptors and ephrin-B ligands expressed within the perivascular niche of dental pulp have been implicated following tooth injury. We propose that ele...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034509342363
更新日期：2009-09-01 00:00:00
abstract：:Vietnamese immigrant and Norwegian children, matched according to caries experience, age, and sex, were compared with respect to S. mutans in dental plaque and in saliva. Regardless of ethnic group, S. mutans prevalence was highest in plaque over caries lesions and from fissures, and lowest in plaque from smooth surfa...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630120801
更新日期：1984-12-01 00:00:00
abstract：:An in vitro model has been developed for measurement of initial attachment of 3H-labeled human gingival fibroblasts (HGF) and periodontal ligament cells (HPDL cells) to sieved dentin powder. Reproducible attachment was obtained and was closely related to the number of plated cells, the amount of dentin powder, the tem...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720030901
更新日期：1993-03-01 00:00:00
abstract：:Various etching methods are examined with respect to their ability to induce the surface nucleation and growth of fluorapatite from solutions of low, sustained supersaturation with respect to hydroxyapatite and fluorapatite. The constant composition kinetics method enables the rates of remineralization to be precisely...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345820610091301
更新日期：1982-09-01 00:00:00
abstract：:The oral cavity contains a rich consortium of exopolysaccharide-producing microbes. These extracellular polysaccharides comprise a major component of the oral biofilm. Together with extracellular proteins, DNA, and lipids, they form the biofilm matrix, which contributes to bacterial colonization, biofilm formation and...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034519845001
更新日期：2019-07-01 00:00:00
abstract：:The object of the present study was an attempt to relate fluoride concentration in enamel, caries experience, and the degree of fluorosis in a community residing in an area with a high level of fluoride. A significant difference was found between the male and female samples for the F and D parameters. A positive corre...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345760550012001
更新日期：1976-01-01 00:00:00
abstract：:Vitamin D, an anti-inflammatory mediator, has potential benefits for physical and oral health. Although it is produced endogenously, some individuals have a greater need for dietary and supplemental sources. This repeated-measures cross-sectional study assessed associations between total vitamin D intake and periodont...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513495239
更新日期：2013-08-01 00:00:00
abstract：:Matrix metalloproteinases (MMPs) produced by resident and inflammatory cells in response to periodontopathogens play a major role in periodontal tissue destruction. Our aim was to investigate the effects of A-type cranberry proanthocyanidins (AC-PACs) on: (i) the production of various MMPs by human monocyte-derived ma...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034509339487
更新日期：2009-07-01 00:00:00
abstract：:The ability of adhesive resins to restore the physical properties of demineralized dentin has not been well-documented. The unfilled resins that are used for adhesion have relatively low moduli of elasticity and limited ability to increase dentin stiffness, although they may increase the ultimate tensile strength of d...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345950740041001
更新日期：1995-04-01 00:00:00
abstract：:We have investigated the role of the activation of nuclear poly(ADP-ribose) polymerase (PARP) enzyme, a mediator of downstream nitric oxide toxicity, using a combined approach of pharmacological inhibition and genetic disruption in a ligature-induced-periodontitis model in rats and mice. Immunohistochemical analysis r...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910308201210
更新日期：2003-12-01 00:00:00
abstract：:There is a large variability between and among individuals in the physiology of mastication, but it is not known whether this produces a similar variability in the particle sizes of food boluses at the end of the chewing process. Food boluses obtained just before swallowing were analyzed in ten subjects (aged 36.7 +/-...
journal_title：Journal of dental research
pub_type： 临床试验,杂志文章
doi：10.1177/154405910408300713
更新日期：2004-07-01 00:00:00
abstract：:Titanium-polymethacrylate composite was prepared as an x-ray-opaque filler for composite core materials. The base monomers of the composite were 2,2-bis [4-(3-methacryloyloxy-2-hydroxypropoxy) phenyl] propane (Bis-GMA) and triethyleneglycol dimethacrylate (TEGDMA). Pure titanium powder was used as a radiopaque element...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345920710010201
更新日期：1992-01-01 00:00:00
abstract：:Dental caries is a microbially mediated disease that can result in significant tooth structure degradation. Although the preponderance of lesions is treated by surgical intervention, various strategies have been developed for its noninvasive management. Here, we use a novel approach for noninvasive treatment based on ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515619370
更新日期：2016-03-01 00:00:00
abstract：:Primary cilia regulate several developmental processes and mediate hedgehog signaling. To study their roles in cranial base development, we created conditional mouse mutants deficient in Polaris, a critical primary cilium component, in cartilage. Mutant post-natal cranial bases were deformed, and their synchondrosis g...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034509337775
更新日期：2009-06-01 00:00:00
abstract：:Although pulp fibroblasts are a major cell type in dental pulp, their roles in microbial recognition and pulpal inflammation are not well-understood. Considering the pivotal role of Toll-like receptors (TLRs) in the recognition of micro-organisms, we hypothesized that TLRs on pulp fibroblasts may induce inflammatory s...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034509354720
更新日期：2010-02-01 00:00:00
abstract：:A procedure for measuring nasal airway resistance using posterior rhinorheometry is described. Baseline nasal airway resistances +/- 1 S.D. at an airflow of 0.5 L/sec were found to be 1.077 +/- 0.683 cm H2O for inhalation and 1.359 +/- 0.792 cm H2O for exhalation. Application of either cold water (4 to 6 C) or warm wa...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560110301
更新日期：1977-11-01 00:00:00
abstract：:Cementum is known to be growth-hormone (GH)-responsive, but to what extent is unclear. This study examines the effects of extremes of GH status on cementogenesis in three lines of genetically modified mice; GH excess (giant), GH antagonist excess (dwarf), and GH receptor-deleted (GHR-KO) (dwarf). Age-matched mandibula...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910408300107
更新日期：2004-01-01 00:00:00
abstract：:Human saliva contains a number of phosphorylated acidic proline-rich proteins (APRP). Monkey parotid saliva contains a similar protein with the same phosphorylated sequences as the human proteins. A crude protein kinase was prepared from Macaca fascicularis parotid glands which phosphorylated human APRP. The enzyme wa...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650030601
更新日期：1986-03-01 00:00:00
abstract：:Autonomic and behavioral responses to seven dental procedures were studied in 21 pedodontic patients aged six to 12. When mean pulse rate, pulse amplitude, absolute skin conductance, and skin-conductance responses were compared over all subjects, the injection of the local anesthetic consistently elicited the greatest...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345830620060801
更新日期：1983-06-01 00:00:00
abstract：:An infrared spectroscopic study has been made of the development of crystallinity (hopeite) in dental zinc phosphate cements. Crystallization in the bulk of a cement is prevented only by the incorporation, in the liquid, of aluminum which forms complexes with phosphoric acid. The development of surface crystallinity i...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345780570021801
更新日期：1978-02-01 00:00:00
abstract：:Dickkopf-related protein 1 (DKK1) is a potent inhibitor of Wnt/β-catenin signaling. Dkk1-null mutant embryos display severe defects in head induction. Conversely, targeted expression of Dkk1 in dental epithelial cells leads to the formation of dysfunctional enamel knots and subsequent tooth defects during embryonic de...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034511421926
更新日期：2011-11-01 00:00:00
abstract：:The surface enamel of fetal bovine teeth was stained with GBHA to indicate the position of bands of smooth-ended and ruffle-ended ameloblasts relative to the developing enamel. The boundaries of the bands were scored, under a dissecting microscope, and the bulk enamel under each band was collected. The enamel samples ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345880670060901
更新日期：1988-06-01 00:00:00
abstract：:This study contains the first part of a research project in which the applicability of fracture mechanics parameters to predict failure of a restored tooth was investigated. Fracture mechanics parameters have been used in dental research before, but were restricted to comparative studies between various brands of comp...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345880670060601
更新日期：1988-06-01 00:00:00
abstract：:It has not been established whether transmission of mutans streptococci occurs between unrelated children older than 4 years of age. The aim of the study was to investigate the possible transmission of mutans streptococci genotypes from child to child in kindergarten. We studied 96 children (ages 5-6 yrs) in three San...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034509353400
更新日期：2010-01-01 00:00:00
abstract：:Histone deacetylases (HDACs) are important regulators of gene expression that are aberrantly regulated in several inflammatory and infectious diseases. HDAC inhibitors (HDACi) suppress inflammatory activation of various cell types through epigenetic and non-epigenetic mechanisms, and ameliorate pathology in a mouse mo...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034519885088
更新日期：2020-01-01 00:00:00
abstract：:The destabilizing effect of endodontic treatment upon teeth is still controversial. The purpose of this study was to investigate the effects of different steps of endodontic treatments upon the rigidity of teeth. Extracted untreated central maxillary anterior teeth were loaded (3.75 N), and deformations of the root we...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910608500416
更新日期：2006-04-01 00:00:00
abstract：:Relative glycogen synthetic abilities of resting cells of fresh clinical isolates of Actinomyces viscosus and Actinomyces naeslundii originating from dental plaque samples over root surface caries lesions and non-carious sites were studied under anaerobic conditions at a constant pH of 7.0, with U-(14C)-glucose used a...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650060701
更新日期：1986-06-01 00:00:00
abstract：:In mineralizing hamster molars, the influence of several inhibitors on p-NPP-ase has been demonstrated, and compared with their effect on PPi-ase, known to belong to the same enzyme. Whereas the latter activity is much more physiological, p-NPP is a better substrate to distinguish between the effects of bivalent catio...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560102701
更新日期：1977-10-01 00:00:00
