Role of the activation of the nuclear enzyme poly(ADP-ribose) polymerase in the pathogenesis of periodontitis.

abstract：:Dental plaque collected from the label aspect of the anterior dentition of children harbored Neisseria that synthesized an extracellular iodophilic polysaccharide (EIP) from sucrose. Gas chromatograms of fully-acetylated EIP derivatives indicated that glucose (97%) and galactose (3%) were the only monosaccharide const...

journal_title：Journal of dental research

authors： Ruby JD,Shirey RE,Gerencser VF,Stelzig DA

更新日期：1982-05-01 00:00:00

abstract：:Greater fluoride concentrations were obtained in enamel treated with phosphate/fluoride solutions than in that treated with TiF4 at similar pH's (1.0) and F concentrations (0.6M F and 1.6M F). However, fluoride solution without added phosphate at pH 1.0 and 1.6M F concentration produced lower fluoride concentrations i...

journal_title：Journal of dental research

authors： Clarkson B,Wefel J

更新日期：1979-02-01 00:00:00

abstract：:Joining a brittle veneer to a strong ceramic core with an adhesive offers potential benefits over current fabrication methods for all-ceramic crowns. We tested the hypothesis that such joining can withstand subsurface radial cracking in the veneer, from enhanced flexure in occlusal loading, as well as in the core. Cri...

journal_title：Journal of dental research

authors： Lee JJ,Kwon JY,Bhowmick S,Lloyd IK,Rekow ED,Lawn BR

更新日期：2008-04-01 00:00:00

abstract：:A/Jax mice were injected with 50 muCi of 3H cortisol and 10 mg of cortisone acetate on day 12 of gestation. At various intervals after injection, the maternal liver, placenta, yolk sac, and the fetal jaws were removed and analyzed by thin-layer chromatography in conjunction with oxidative combustion and liquid scintil...

journal_title：Journal of dental research

authors： Spain KM,Kisieleski W,Wood NK

更新日期：1975-09-01 00:00:00

abstract：:The sensitizing potential of three periodontal dressing materials was evaluated by the guinea pig maximization test. The results indicated a difference in the sensitization rate of the three materials. ...

journal_title：Journal of dental research

authors： Haugen E,Hensten-Pettersen A

更新日期：1978-11-01 00:00:00

abstract：:Incubation of saliva supernatant after three hours at 37 C revealed that salivary anionic proteins were susceptible to enzymatic attack by salivary enzymes not removable by centrifugation at 10,000 g. In the presence of washed suspensions of S mutans or S sanguis additional changes in electrophoretic behavior of anion...

journal_title：Journal of dental research

authors： Cowman RA,Fitzgerald RJ

更新日期：1975-03-01 00:00:00

abstract：:The effects of oral rinses on enamel fluoride uptake, caries, and plaque pH in rats were investigated by use of (1) an acidic calcium phosphate solution (CPS) saturated with dicalcium phosphate dihydrate (DCPD) and (2) a 1% fluoride solution. Osborne-Mendel rats, 19 days of age, were randomly assigned to one of four m...

journal_title：Journal of dental research

authors： Schreiber CT,Shern RJ,Chow LC,Kingman A

更新日期：1988-06-01 00:00:00

abstract：:In the rat parotid acinar cell, methacholine caused an increase in [Ca2+]i as determined by quin-2 fluorescence. The increase in [Ca2+]i was initially independent of, and subsequently dependent on, the presence of extracellular Ca2+, indicating mobilization of intracellular Ca2+, as well as activation of Ca2+ entry. M...

journal_title：Journal of dental research

authors： Aub DL,Putney JW Jr

更新日期：1987-02-01 00:00:00

abstract：:A conceptual means of obtaining improved bonding between filler particles and the polymeric binders of composites is presented. It involves preparing glass particles that separate into two interconnected vitreous phases when heated to an appropriate temperature, and then etching these to produce a porous surface layer...

journal_title：Journal of dental research

authors： Bowen RL,Reed LE

更新日期：1976-09-01 00:00:00

abstract：:The most frequent complaints registered against composite restorations are stained margins and a rough surface. The stained margins have many causes such as (1) fracturing or crazing of enamel during preparation of the cavity, (2) using a composite having an excessive curing shrinkage, (3) manipulating too slowly, whi...

journal_title：Journal of dental research

authors： Rupp NW

更新日期：1979-05-01 00:00:00

abstract：:The number of molars selected for prophylactic removal varies widely among general dental practitioners and oral surgeons. To understand the basis for such variations, we investigated two hypotheses: (1) Individual judgment strategies will differ concerning the use of cues (items of information), and (2) few dentists ...

journal_title：Journal of dental research

authors： Knutsson K,Lysell L,Rohlin M

更新日期：2000-12-01 00:00:00

abstract：:An adhesive opaque resin for veneering on cast metal was developed with 4-methacryloxyethyl trimellitate anhydride and poly (methyl methacrylate)-coated titanium dioxide prepared by aqueous phase polymerization. The opaque resin was a modified 4-META/MMA-TBB resin. The powder consisted of 20% of the encapsulated mater...

journal_title：Journal of dental research

authors： Matsumura H,Nakabayashi N

更新日期：1988-01-01 00:00:00

abstract：:Temperature elevations were measured in the pulp chamber of full cast crown preparations during impression taking with modelling compound in copper bands. Uncontrolled flaming, controlled flaming, and water heating of the bands produced temperatures of 53, 44, and 41.5 C, respectively. The time involved in restoring t...

journal_title：Journal of dental research

authors： Grajower R,Kaufman E,Stern N

更新日期：1975-03-01 00:00:00

abstract：:Dental caries is initiated by demineralization of the tooth surface through acid production by sugar metabolism of supragingival plaque microflora. To elucidate the sugar metabolic system, we used CE-MS to perform metabolomics of the central carbon metabolism, the EMP pathway, the pentose-phosphate pathway, and the TC...

journal_title：Journal of dental research

authors： Takahashi N,Washio J,Mayanagi G

更新日期：2010-12-01 00:00:00

abstract：:Samples of a base mental alloy were cast and welded together using a conventional welding procedure. The joints were loaded and placed either in a corrosive environment or in air for varying time periods. The tensile and shear strength of the joints was unaffected by the corrosive environment, and the joints, despite ...

journal_title：Journal of dental research

authors： MacEntee MI,Hawbolt EB,Zahel JI

更新日期：1981-02-01 00:00:00

abstract：:Previous investigations have shown a clear association between the presence of the enzyme aspartate aminotransferase (AST) in gingival crevicular fluid (GCF) and clinical evidence of periodontal disease in humans, as well as in the beagle dog model. This paper describes a 26-week study that uses the beagle dog model o...

journal_title：Journal of dental research

authors： Cohen RL,Alves ME,Crawford JM,McSwiggin T,Chambers DA

更新日期：1991-06-01 00:00:00

abstract：:Gingival overgrowth tissues have thickened connective tissue stroma, sometimes accompanied by the increased presence of collagen fibers, thickened epithelia, and elongated rete pegs. We have previously shown that expression of CCN2, also known as connective tissue growth factor (CTGF), correlates positively with the d...

journal_title：Journal of dental research

authors： Kantarci A,Nseir Z,Kim YS,Sume SS,Trackman PC

更新日期：2011-07-01 00:00:00

abstract：:Branching morphogenesis is essential for the formation of salivary glands, kidneys, lungs, and many other organs during development, but the mechanisms underlying this process are not adequately understood. Microarray and other gene expression methods have been powerful approaches for identifying candidate genes that ...

journal_title：Journal of dental research

authors： Hsu JC,Di Pasquale G,Harunaga JS,Onodera T,Hoffman MP,Chiorini JA,Yamada KM

更新日期：2012-02-01 00:00:00

abstract：:Despite the recognized link between aging and cancer, most preclinical studies in experimental tumor models are conducted with 6- to 8-wk-old rodents. The goal of the present study was to examine the impact of age on tumor incidence, growth, and microenvironmental characteristics in mouse models of head and neck squam...

journal_title：Journal of dental research

authors： Vincent-Chong VK,DeJong H,Rich LJ,Patti A,Merzianu M,Hershberger PA,Seshadri M

更新日期：2018-10-01 00:00:00

abstract：:Cementum is known to be growth-hormone (GH)-responsive, but to what extent is unclear. This study examines the effects of extremes of GH status on cementogenesis in three lines of genetically modified mice; GH excess (giant), GH antagonist excess (dwarf), and GH receptor-deleted (GHR-KO) (dwarf). Age-matched mandibula...

journal_title：Journal of dental research

authors： Smid JR,Rowland JE,Young WG,Daley TJ,Coschigano KT,Kopchick JJ,Waters MJ

更新日期：2004-01-01 00:00:00

abstract：:An oral radiotelemetric technique was used to determine whether a range of efficient buffers had the capacity to control the levels of hydrogen ions within dental plaque in the presence of sucrose. It was found that the buffers failed to control both the intensity and duration of the acid produced. ...

journal_title：Journal of dental research

authors： Clarke NG,Dowdell LR

更新日期：1976-09-01 00:00:00

abstract：:Caregivers' health literacy has emerged as an important determinant of young children's health care and outcomes. We examined the hypothesis that caregivers' health literacy influences children's oral-health-care-related expenditures. This was a prospective cohort study of 1,132 child/caregiver dyads (children's mean ...

journal_title：Journal of dental research

authors： Vann WF Jr,Divaris K,Gizlice Z,Baker AD,Lee JY

更新日期：2013-07-01 00:00:00

abstract：:The purpose of this study was to investigate the genotoxic effects of chronic fluoride exposure on mammalian cells in vivo by use of the mouse bone-marrow micronucleus test and the sperm morphology methodology. Mice of genotype B6C3F1 were obtained at weaning and maintained on a low-fluoride diet (less than 0.2 ppm F)...

journal_title：Journal of dental research

authors： Dunipace AJ,Zhang W,Noblitt TW,Li Y,Stookey GK

更新日期：1989-11-01 00:00:00

abstract：:Protease-activated receptors (PARs) are G protein-coupled receptors, which are activated by proteolytical cleavage of the amino-terminus and act as sensors for extracellular proteases. We hypothesized that PAR-1 and PAR-2 can be modulated by inflammatory stimulus in human dental pulp cells. PAR-1 and PAR-2 gene expres...

journal_title：Journal of dental research

authors： Alvarez MMP,Moura GE,Machado MFM,Viana GM,de Souza Costa CA,Tjäderhane L,Nader HB,Tersariol ILS,Nascimento FD

更新日期：2017-12-01 00:00:00

abstract：:The cariostatic benefit from water fluoridation is indisputable, but the knowledge of possible adverse effects on bone and fracture risk due to fluoride exposure is ambiguous. The association between long-term (chronic) drinking water fluoride exposure and hip fracture (ICD-7-9: '820' and ICD-10: 'S72.0-S72.2') was as...

journal_title：Journal of dental research

authors： Näsman P,Ekstrand J,Granath F,Ekbom A,Fored CM

更新日期：2013-11-01 00:00:00

abstract：:The aim of this study was to test the hypothesis that the chewing of xylitol- or xylitol/sorbitol-containing chewing gum reduces plaque formation and the acidogenic potential of dental plaque. Thirty healthy volunteers aged from 19 to 28 yrs were randomly allocated to one of three test groups, chewing either xylitol-,...

journal_title：Journal of dental research

authors： Scheie AA,Fejerskov O,Danielsen B

更新日期：1998-07-01 00:00:00

abstract：:A complex feedback mechanism between parathyroid hormone (PTH), 1,25(OH)2D3 (1,25D), and fibroblast growth factor 23 (FGF-23) maintains mineral homeostasis, in part by regulating calcium and phosphate absorption/reabsorption. Previously, we showed that 1,25D regulates mineral homeostasis by repressing dentin matrix pr...

journal_title：Journal of dental research

authors： Wang L,Tran AB,Nociti FH Jr,Thumbigere-Math V,Foster BL,Krieger CC,Kantovitz KR,Novince CM,Koh AJ,McCauley LK,Somerman MJ

更新日期：2015-10-01 00:00:00

abstract：:The differential diagnosis of dental wear lesions affects their clinical management. We hypothesized that surface texture parameters can differentiate simulated erosion, abrasion, and erosion-abrasion lesions on human enamel and dentin. This in vitro study comprised 2 parts (both factorial 4 × 2), with 4 lesion types ...

journal_title：Journal of dental research

authors： Hara AT,Livengood SV,Lippert F,Eckert GJ,Ungar PS

更新日期：2016-05-01 00:00:00

abstract：:Breastfeeding is important for health and development. Yet, the interaction between breastfeeding duration and usage of fluoridated water on caries experience has not been investigated. This study examined exposure to fluoridation as an effect modifier of the association between breastfeeding duration and caries. The ...

journal_title：Journal of dental research

authors： Ha DH,Spencer AJ,Peres KG,Rugg-Gunn AJ,Scott JA,Do LG

更新日期：2019-07-01 00:00:00

abstract：:Monolayers of feline parotid acinar cells were infected with feline rhinotracheitis herpes virus. Membrane potentials and input resistances were measured before and during infection. Uninfected acinar cells had an average membrane potential of -51 mV and resistances from 6 to 120 mega-ohms; cells infected for more tha...

journal_title：Journal of dental research

authors： Weigel RJ,Fritz ME,Nahmias AJ

更新日期：1981-12-01 00:00:00