Influence of various inhibitors on alkaline phosphatase in calicifying hamster molars, employing paranitrophenyl phosphate as substrate.

abstract：:Porphyromonas gingivalis dihydroceramides are found in extracts of calculus-contaminated root surfaces, diseased gingival tissue, and atherosclerotic plaques. These ceramides have been shown to promote inflammatory secretory responses in gingival fibroblasts. Little is known about their effects on the vascular system....

journal_title：Journal of dental research

authors： Zahlten J,Riep B,Nichols FC,Walter C,Schmeck B,Bernimoulin JP,Hippenstiel S

更新日期：2007-07-01 00:00:00

abstract：:Previous research, in which the bonding effectiveness of the 3 self-etch monomers HAEPA, EAEPA, and MAEPA was determined, showed that MAEPA was most effective. In this study, the molecular interactions of these monomers with hydroxyapatite and dentin were investigated by combining x-ray diffraction, infrared spectrosc...

journal_title：Journal of dental research

authors： Yoshihara K,Yoshida Y,Hayakawa S,Nagaoka N,Torii Y,Osaka A,Suzuki K,Minagi S,Van Meerbeek B,Van Landuyt KL

更新日期：2011-05-01 00:00:00

abstract：:We previously demonstrated that an anti-caries DNA vaccine intranasally administered with recombinant flagellin protein as a mucosal adjuvant enhanced salivary IgA response and conferred better protection against caries. However, the relatively weak immunogenicity of DNA vaccines and the necessity for a large quantity...

journal_title：Journal of dental research

authors： Sun Y,Shi W,Yang JY,Zhou DH,Chen YQ,Zhang Y,Yang Y,He BX,Zhong MH,Li YM,Cao Y,Xiao Y,Li W,Yu J,Li YH,Fan MW,Yan HM

更新日期：2012-10-01 00:00:00

abstract：:Zirconia-based restorations often fracture from chipping and/or delamination of the porcelain veneers. We hypothesized that veneer chipping/delamination is a result of the propagation of near-contact-induced partial cone cracks on the occlusal surface under mastication. Masticatory loading involves the opposing tooth ...

journal_title：Journal of dental research

authors： Kim JW,Kim JH,Janal MN,Zhang Y

更新日期：2008-12-01 00:00:00

abstract：:Bone and dentin share similar biochemical compositions and physiological properties. Dentin, a major tooth component, is formed by odontoblasts; in contrast, bone is produced by osteoblasts. Osterix (Osx), a zinc finger-containing transcription factor, has been identified as an essential regulator of osteoblast differ...

journal_title：Journal of dental research

authors： Kim TH,Bae CH,Lee JC,Kim JE,Yang X,de Crombrugghe B,Cho ES

更新日期：2015-03-01 00:00:00

abstract：:The field of dental materials has undergone more of a revolution than an evolution over the past 100 y. The development of new products, especially in the past half century, has occurred at a staggering pace, and their introduction to the market has been equally impressive. The movement has mostly come in the area of ...

journal_title：Journal of dental research

authors： Bayne SC,Ferracane JL,Marshall GW,Marshall SJ,van Noort R

更新日期：2019-03-01 00:00:00

abstract：:One-step incomplete excavation seals caries-affected dentin under a restoration and appears to be advantageous in the treatment of deep lesions. However, it is impossible to discriminate radiographically between intentionally left, arrested lesions and overlooked or active lesions. This diagnostic uncertainty decrease...

journal_title：Journal of dental research

authors： Schwendicke F,Meyer-Lueckel H,Schulz M,Dörfer CE,Paris S

更新日期：2014-06-01 00:00:00

abstract：:Iodoacetate at 10(-3) M and 10(-4) M concentrations was found to strongly inhibit incorporation of both 14C-choline and 3H-inositol into phospholipids of calvaria from newborn rats; it had somewhat less effect on ethanolamine incorporation and almost no effect on serine incorporation. Similar though less dramatic resu...

journal_title：Journal of dental research

authors： Dirksen TR,Schuster GS,McKinney R,Bustos SE

更新日期：1975-09-01 00:00:00

abstract：:A procedure for measuring nasal airway resistance using posterior rhinorheometry is described. Baseline nasal airway resistances +/- 1 S.D. at an airflow of 0.5 L/sec were found to be 1.077 +/- 0.683 cm H2O for inhalation and 1.359 +/- 0.792 cm H2O for exhalation. Application of either cold water (4 to 6 C) or warm wa...

journal_title：Journal of dental research

authors： Martin JS,Tansy MF

更新日期：1977-11-01 00:00:00

abstract：:Successive active phases observed in periodontal diseases may be explained either by a sudden activation of the pro-forms of tissue-stored degradative enzymes such as metalloproteinases (MMPs) or by an imbalance between metalloproteinases and their tissue inhibitors (TIMPs). To discriminate between these two hypothese...

journal_title：Journal of dental research

authors： Soell M,Elkaim R,Tenenbaum H

更新日期：2002-03-01 00:00:00

abstract：:Priming with tumor antigens is one of the most important strategies in cancer immunotherapy. To enhance tumor antigenicity, OK-432, a streptococcal preparation, was coupled to squamous cell carcinoma (KLN-205) by means of a 0.2% glutaraldehyde method. The purpose of this study was to investigate whether OK-432-conjuga...

journal_title：Journal of dental research

authors： Li X,Bukawa H,Hirota M,Tsuyuki Y,Omura S,Fujita K

更新日期：2003-08-01 00:00:00

abstract：:The discovery and implementation of fluoride in the prevention of dental caries is often praised as one of the most important achievements in health care. In the early 20th century, it took 30 y to identify fluoride as the cause of enamel mottling but also of reduced caries prevalence in a population drinking water co...

journal_title：Journal of dental research

authors： Ten Cate JM,Buzalaf MAR

更新日期：2019-07-01 00:00:00

abstract：:Numerous studies have demonstrated that many older adults have problems chewing, pain, difficulties in eating, and problems in social relationships because of oral disorders. However, it is not clear if these functional and psychosocial outcomes affect broader psychological well-being and life satisfaction. Consequent...

journal_title：Journal of dental research

authors： Locker D,Clarke M,Payne B

更新日期：2000-04-01 00:00:00

abstract：:Three single-composition, high-copper amalgams were analyzed for the composition of their before- and after-reaction phases. The method used was electron probe microanalysis. The results may be summarized as follows: All alloys consist essentially of Ag3Sn (gamma), Cu3Sn (epsilon), and, in some cases, Ag4Sn (beta). Wh...

journal_title：Journal of dental research

authors： Mahler DB,Adey JD

更新日期：1984-06-01 00:00:00

abstract：:Previous studies have indicated that tooth-bleaching agents contain potentially hazardous chemicals. The present study evaluates the acute toxicity of a commercially available tooth-bleaching agent and carbamide peroxide, which is the active bleaching ingredient. Rats were dosed by stomach gavage, i.e., via a stomach ...

journal_title：Journal of dental research

authors： Dahl JE,Becher R

更新日期：1995-02-01 00:00:00

abstract：:Chronic periodontitis is a multi-factorial disease involving anaerobic bacteria and the generation of an inflammatory response, including the production of metalloproteinases, pro-inflammatory cytokines, and eicosanoids. Hypochlorous acid (HOCl) and taurine-N-monochloramine (TauCl) are the end-products of the neutroph...

journal_title：Journal of dental research

authors： Mainnemare A,Mégarbane B,Soueidan A,Daniel A,Chapple IL

更新日期：2004-11-01 00:00:00

abstract：:Large mandibular defects are difficult to reconstruct with good functional and aesthetic outcomes because of the complex geometry of craniofacial bone. While the current gold standard is free tissue flap transfer, this treatment is limited in fidelity by the shape of the harvested tissue and can result in significant ...

journal_title：Journal of dental research

authors： Tatara AM,Wong ME,Mikos AG

更新日期：2014-12-01 00:00:00

abstract：:The term "artificial intelligence" (AI) refers to the idea of machines being capable of performing human tasks. A subdomain of AI is machine learning (ML), which "learns" intrinsic statistical patterns in data to eventually cast predictions on unseen data. Deep learning is a ML technique using multi-layer mathematical...

journal_title：Journal of dental research

authors： Schwendicke F,Samek W,Krois J

更新日期：2020-07-01 00:00:00

abstract：:A search was made for expression of genes for proline-rich proteins (PRPs) and other salivary-type proteins, including statherin and histatins, in taste-bud tissues of mice and primates because of previous genetic findings in mice (Azen et al., 1986) that Prp and taste genes for certain bitter substances are either th...

journal_title：Journal of dental research

authors： Azen EA,Hellekant G,Sabatini LM,Warner TF

更新日期：1990-11-01 00:00:00

abstract：:The destabilizing effect of endodontic treatment upon teeth is still controversial. The purpose of this study was to investigate the effects of different steps of endodontic treatments upon the rigidity of teeth. Extracted untreated central maxillary anterior teeth were loaded (3.75 N), and deformations of the root we...

journal_title：Journal of dental research

authors： Lang H,Korkmaz Y,Schneider K,Raab WH

更新日期：2006-04-01 00:00:00

abstract：:Lactoferrin is one of a number of multifunctional proteins that are present in or on all mucosal surfaces throughout the body. Levels of lactoferrin are consistently elevated in inflammatory diseases such as arthritis, inflammatory bowel diseases, corneal disease, and periodontitis. Single-nucleotide polymorphisms (SN...

journal_title：Journal of dental research

authors： Fine DH

更新日期：2015-06-01 00:00:00

abstract：:The gingival microbiota in beagle dogs was investigated during a period of 42 days after the placement of continuous wire and arch bar splints. The splints were found to induce an increase in helicoidal-shaped micro-organisms and black-pigmented Bacteroides. Two different asaccharolytic Bacteroides types were isolated...

journal_title：Journal of dental research

authors： Mikx FH,Ngassapa DN,Reijntjens FM,Maltha JC

更新日期：1984-11-01 00:00:00

abstract：:Phosphorylated extracellular matrix proteins, including matrix extracellular phosphoprotein (MEPE), are involved in the formation and mineralization of dental tissues. In this study, we evaluated the potential of Dentonin, a synthetic peptide derived from MEPE, to promote the formation of reparative dentin. Agarose be...

journal_title：Journal of dental research

authors： Six N,Septier D,Chaussain-Miller C,Blacher R,DenBesten P,Goldberg M

更新日期：2007-08-01 00:00:00

abstract：:Dental caries is initiated by demineralization of the tooth surface through acid production by sugar metabolism of supragingival plaque microflora. To elucidate the sugar metabolic system, we used CE-MS to perform metabolomics of the central carbon metabolism, the EMP pathway, the pentose-phosphate pathway, and the TC...

journal_title：Journal of dental research

authors： Takahashi N,Washio J,Mayanagi G

更新日期：2010-12-01 00:00:00

abstract：:Potentially significant associations between periodontal disease and chronic kidney disease (CKD) have been reported in recent studies. The aim of this cross-sectional study was to investigate the association between serum antibody to the periodontal pathogen Porphyromonas gingivalis (P. gingivalis) and CKD in 215 Jap...

journal_title：Journal of dental research

authors： Iwasaki M,Taylor GW,Manz MC,Kaneko N,Imai S,Yoshihara A,Miyazaki H

更新日期：2012-09-01 00:00:00

abstract：:Caries increment is affected by sugar-sweetened beverage (SSB) consumption. Taxing SSBs could reduce sugar consumption and caries increment. The authors aimed to estimate the impact of a 20% SSB sales tax on caries increment and associated treatment costs (as well as the resulting tax revenue) in the context of German...

journal_title：Journal of dental research

authors： Schwendicke F,Thomson WM,Broadbent JM,Stolpe M

更新日期：2016-11-01 00:00:00

abstract：:The type of attachment that is used in oral rehabilitation by means of implant-retained mandibular overdentures may influence the retention and the stability of the denture. In this study, we examined the hypothesis that a better retention and stability of the denture improve the oral function. Eighteen edentulous sub...

journal_title：Journal of dental research

authors： van Kampen FM,van der Bilt A,Cune MS,Bosman F

更新日期：2002-03-01 00:00:00

abstract：:Extracellular matrix (ECM) mineralization is regulated by mineral ion availability, proteins, and other molecular determinants. To investigate protein regulation of mineralization in tooth dentin and cementum, and in alveolar bone, we expressed matrix Gla protein (MGP) ectopically in bones and teeth in mice, using an ...

journal_title：Journal of dental research

authors： Kaipatur NR,Murshed M,McKee MD

更新日期：2008-09-01 00:00:00

abstract：:The effects of substituting gluconate for extracellular Cl, and of treatment with various ion transport blockers, on cytosol pH (pHi) and secretion by the acetylcholine stimulated rat mandibular gland were studied in vitro. Gluconate replacement increased pHi from 7.12 +/- 0.02 to 7.27 +/- 0.04, caused secretory rate ...

journal_title：Journal of dental research

authors： Young JA,Cook DI,Evans LA,Pirani D

更新日期：1987-02-01 00:00:00

abstract：:Van der Woude syndrome (VWS) is an autosomal-dominant oral facial disorder. To find a gene mutation in a Japanese family using fingernail DNA samples, we performed this study. We hypothesized that a gene mutation in IRF6 might be involved in VWS, and that fingernail DNA samples may be valuable for detecting such mutat...

journal_title：Journal of dental research

authors： Matsuzawa N,Shimozato K,Natsume N,Niikawa N,Yoshiura K

更新日期：2006-12-01 00:00:00