Abstract：
:The field of dental materials has undergone more of a revolution than an evolution over the past 100 y. The development of new products, especially in the past half century, has occurred at a staggering pace, and their introduction to the market has been equally impressive. The movement has mostly come in the area of improved esthetics, marked by the gradual replacement of dental amalgam with dental composite and all-metal and porcelain-fused-to-metal indirect restorations with reinforced dental ceramics, all made possible by the rapid improvements in dental adhesive materials. This article covers the time course of dental materials development over the past century in which the Journal of Dental Research has been published. While there have been advances in nearly all materials used in the field, this article focuses on several areas, including dental amalgam, dental composites and light curing, dental adhesives and dental cements, ceramics, and new functional repair materials. A few short statements on future advances will be included at the end.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Bayne SC,Ferracane JL,Marshall GW,Marshall SJ,van Noort Rdoi
10.1177/0022034518822808subject
Has Abstractpub_date
2019-03-01 00:00:00pages
257-265issue
3eissn
0022-0345issn
1544-0591journal_volume
98pub_type
杂志文章abstract：:A numerical model of the mandible, its articulating surfaces, and the forces exerted by the primary masticatory muscles has been developed for the purpose of investigating loading of the temporomandibular joint. Evidence is presented which shows that the temporomandibular joint. Evidence is presented which shows that ...
journal_title：Journal of dental research
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doi：10.1177/00220345860650080201
更新日期：1986-08-01 00:00:00
abstract：:Mutations and common polymorphisms in interferon regulatory factor 6 ( IRF6) are associated with both syndromic and nonsyndromic forms of cleft lip/palate (CLP). To date, much of the focus on this transcription factor has been on identifying its direct targets and the gene regulatory network in which it operates. Nota...
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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abstract：:Proteolytic hydrolysis of casein and porcine or bovine glycoproteins by S mutans was demonstrated in the present study. Caseinolytic activity was found in both the soluble contents of the cells and the cellular debris after rupture of the cells. However, caseinolytic activity could not be demonstrated after growth in ...
journal_title：Journal of dental research
pub_type： 杂志文章
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journal_title：Journal of dental research
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abstract：:Van der Woude syndrome (VWS) is an autosomal-dominant oral facial disorder. To find a gene mutation in a Japanese family using fingernail DNA samples, we performed this study. We hypothesized that a gene mutation in IRF6 might be involved in VWS, and that fingernail DNA samples may be valuable for detecting such mutat...
journal_title：Journal of dental research
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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更新日期：1991-11-01 00:00:00
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journal_title：Journal of dental research
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更新日期：1997-12-01 00:00:00
abstract：:Retinoic acid-inducible gene I (RIG-I) is a cytosolic pattern recognition receptor involved in the sensing of RNA viruses and the initiation of antiviral responses. Fusobacterium nucleatum, a Gram-negative anaerobic bacterium associated with periodontal disease, is capable of invading cells. We hypothesized that F. nu...
journal_title：Journal of dental research
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更新日期：2014-02-01 00:00:00
abstract：:Interfacial bond strengths of light-activated composites were measured as a function of age using a transverse strength test. Bond strength between layers decreased with the age of the initial layer and reflected the setting curves of the composites. The highly-filled composites exhibited the greatest bond strengths. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630101501
更新日期：1984-10-01 00:00:00
abstract：:The spatial relationship of the mandibular condyle to the temporal component of the TMJ is determined quantitatively from lateral tomograms using a new method of measuring specific areas of the joint space. Condyle position along the posteroanterior axis of the joint is expressed as a ratio of the posterior joint spac...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345810600010701
更新日期：1981-01-01 00:00:00
abstract：:Although systemic bone loss accompanying estrogen deficiency has been proposed as a risk factor for periodontal disease in post-menopausal women, the mechanisms involved remain unclear. The objective of this study was to elucidate the potential bone-sparing effect of estrogen (17beta-estradiol, E(2)) via modulation of...
journal_title：Journal of dental research
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doi：10.1177/154405910808700214
更新日期：2008-02-01 00:00:00
abstract：:Previous studies show that both activin and Bmp4 act as crucial mesenchymal odontogenic signals during early tooth development. Remarkably, mice lacking activin-βA ( Inhba-/-) and mice with neural crest-specific inactivation of Bmp4 ( Bmp4ncko/ncko) both exhibit bud-stage developmental arrest of the mandibular molar t...
journal_title：Journal of dental research
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doi：10.1177/0022034517713710
更新日期：2017-09-01 00:00:00
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journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034514555364
更新日期：2015-01-01 00:00:00
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journal_title：Journal of dental research
pub_type： 杂志文章
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更新日期：2000-08-01 00:00:00
abstract：:Pain and discomfort are common problems for patients undergoing orthodontic treatment. We have demonstrated that cortical excitation propagation in the somatosensory and insular cortices (IC) induced by electrical stimulation of the periodontal ligament (PDL) is facilitated 1 d after experimental tooth movement (ETM)....
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abstract：:The object of the present study was an attempt to relate fluoride concentration in enamel, caries experience, and the degree of fluorosis in a community residing in an area with a high level of fluoride. A significant difference was found between the male and female samples for the F and D parameters. A positive corre...
journal_title：Journal of dental research
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abstract：:In the past decade, medical genetic research has generated multiple discoveries, many of which were obtained via genome-wide association studies (GWASs). A major GWAS finding is that the majority of risk variants for complex traits map to noncoding regions. This has resulted in a paradigm shift in terms of the interpr...
journal_title：Journal of dental research
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更新日期：2017-10-01 00:00:00
abstract：:Streptococcus mutans produces 3 types of glucosyltransferase (GTF), whose cooperative action is considered to be essential for its cellular adherence to the tooth surface. However, the precise mechanisms for synthesizing adhesive glucans and the specific roles of each GTF in cellular adherence to smooth surfaces have ...
journal_title：Journal of dental research
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abstract：:Pilocarpine (P) is of potential utility in the treatment of xerostomia. Because optimal development of P dosage forms for humans requires that its pharmacokinetics and pharmacodynamics be defined, this intravenous study of its disposition and associated salivary responses was performed. In a hospital setting, two heal...
journal_title：Journal of dental research
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更新日期：1995-12-01 00:00:00
abstract：:The temporomandibular joint (TMJ) undergoes degenerative changes among patients who suffer from arthritis, and yet the pathogenesis of TMJ osteoarthritis and rheumatoid arthritis is poorly understood. We hypothesized that sustained inflammation in the TMJ induces structural abnormalities, and accordingly characterized...
journal_title：Journal of dental research
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abstract：:The recent bioengineering of complex tooth structures from pig tooth bud tissues suggests the potential for the regeneration of mammalian dental tissues. We have improved tooth bioengineering methods by comparing the utility of cultured rat tooth bud cells obtained from three- to seven-day post-natal (dpn) rats for to...
journal_title：Journal of dental research
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doi：10.1177/154405910408300703
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abstract：:Interleukin (IL)-23 is an essential cytokine involved in expansion of the Th17 lineage, which is associated with many immune-related destructive tissue diseases. We hypothesized that the IL-23-induced Th17 pathway plays a role in periodontal pathology and examined the expression of cytokines, and related molecules, in...
journal_title：Journal of dental research
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