Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth.

abstract：:Cell kinetics of rat molar periodontal ligament (PDL) during orthodontically-induced osteogenesis revealed: 1) primary growth fraction of 59%, 2) proliferating cells from throughout the PDL migrate toward the bone surface, 3) preosteoblasts, capable of forming osteoblasts without synthesizing DNA, are present in the P...

journal_title：Journal of dental research

authors： Roberts WE,Chase DC

更新日期：1981-02-01 00:00:00

abstract：:Light propagation in human dentin exhibits a strong directional dependence featuring the long-known optical magnification property. We hypothesized that this anisotropic effect is caused by multiple scattering at the dentin tubules, and not by fiberoptic effects, as had been previously assumed. We performed measuremen...

journal_title：Journal of dental research

authors： Kienle A,Michels R,Hibst R

更新日期：2006-10-01 00:00:00

abstract：:In the past decade, medical genetic research has generated multiple discoveries, many of which were obtained via genome-wide association studies (GWASs). A major GWAS finding is that the majority of risk variants for complex traits map to noncoding regions. This has resulted in a paradigm shift in terms of the interpr...

journal_title：Journal of dental research

authors： Thieme F,Ludwig KU

更新日期：2017-10-01 00:00:00

abstract：:The objectives of this study were 1) to provide an estimate of the value of the intraclass correlation coefficient (ICC) for dental caries data at tooth and surface level, 2) to provide an estimate of the design effect (DE) to be used in the determination of sample size estimates for future dental surveys, and 3) to e...

journal_title：Journal of dental research

authors： Masood M,Masood Y,Newton JT

更新日期：2015-02-01 00:00:00

abstract：:Investigations of the maturation pattern of rat incisor enamel by quantitative electron microscopy and electron-probe microanalysis indicate that mineralization of rat enamel can be regarded, as in humans, as a regular and progressive process pattern of enamel matrix formation. The species variations that have been pr...

journal_title：Journal of dental research

authors： Glick PL

更新日期：1979-03-01 00:00:00

abstract：:Temporomandibular joint (TMJ) disorders, including degenerative TMJ disease, occur primarily in women of reproductive age. Previous studies showed elevated estrogen levels in subjects with TMJ disorders relative to controls and the presence of estrogen receptors α and β (ERα and ERβ) in TMJ fibrocartilage. Additionall...

journal_title：Journal of dental research

authors： Ahmad N,Chen S,Wang W,Kapila S

更新日期：2018-08-01 00:00:00

abstract：:The Wingless/integrase-1 (Wnt) family of protein ligands and their functional antagonists, secreted frizzled-related proteins (sFRPs), regulate various biological processes ranging from embryonic development to immunity and inflammation. Wnt5a and sFRP5 comprise a typical ligand/antagonist pair, and the former molecul...

journal_title：Journal of dental research

authors： Maekawa T,Kulwattanaporn P,Hosur K,Domon H,Oda M,Terao Y,Maeda T,Hajishengallis G

更新日期：2017-05-01 00:00:00

abstract：:Clinical evidence is lacking regarding the influence of the amount of residual coronal dentin and of post placement on the failure risk of endodontically compromised teeth. The aim of this prospective clinical trial was to assess whether these factors significantly affect the two-year survival of restored pulpless pre...

journal_title：Journal of dental research

authors： Ferrari M,Cagidiaco MC,Grandini S,De Sanctis M,Goracci C

更新日期：2007-08-01 00:00:00

abstract：:The periodontal ligament (PDL) works as a suspensory ligament when external mechanical stress is placed on the teeth. PDL fibroblasts, the principal cells in the PDL, are responsible for many PDL functions. We hypothesized that mechanosensitive ion channels are present in human PDL fibroblasts, which are capable of re...

journal_title：Journal of dental research

authors： Ohara A,Saeki Y,Nishikawa M,Yamamoto Y,Yamamoto G

更新日期：2006-07-01 00:00:00

abstract：:The complexity of human oral functional movements has not been studied in detail quantitatively, and only recently have studies begun to evaluate whether such movements contain sex-specific characteristics. Therefore, the purposes of this study were: (1) to quantify in detail the jaw movements and associated masticato...

journal_title：Journal of dental research

authors： Gerstner GE,Parekh VV

更新日期：1997-03-01 00:00:00

abstract：:Potentially significant associations between periodontal disease and chronic kidney disease (CKD) have been reported in recent studies. The aim of this cross-sectional study was to investigate the association between serum antibody to the periodontal pathogen Porphyromonas gingivalis (P. gingivalis) and CKD in 215 Jap...

journal_title：Journal of dental research

authors： Iwasaki M,Taylor GW,Manz MC,Kaneko N,Imai S,Yoshihara A,Miyazaki H

更新日期：2012-09-01 00:00:00

abstract：:Antigenic alterations to the dentin organic matrix may be detected by an immunohistochemical approach. We hypothesized that alterations in the antigenicity of type I collagen and proteoglycans occur in sclerotic dentin under caries lesions. Transverse sections were prepared from carious teeth in the sclerotic zone and...

journal_title：Journal of dental research

authors： Suppa P,Ruggeri A Jr,Tay FR,Prati C,Biasotto M,Falconi M,Pashley DH,Breschi L

更新日期：2006-02-01 00:00:00

abstract：:A frameshift mutation recently identified within the paired domain of the transcription factor, PAX9, has been linked to a unique form of oligodontia in a single, multigenerational family (Stockton et al., 2000). We now describe the phenotypic and segregation analyses of this remarkable kindred, the initial approach t...

journal_title：Journal of dental research

authors： Goldenberg M,Das P,Messersmith M,Stockton DW,Patel PI,D'Souza RN

更新日期：2000-07-01 00:00:00

abstract：:Three single-composition, high-copper amalgams were analyzed for the composition of their before- and after-reaction phases. The method used was electron probe microanalysis. The results may be summarized as follows: All alloys consist essentially of Ag3Sn (gamma), Cu3Sn (epsilon), and, in some cases, Ag4Sn (beta). Wh...

journal_title：Journal of dental research

authors： Mahler DB,Adey JD

更新日期：1984-06-01 00:00:00

abstract：:The complexity of the periodontal microbiota resembles that of the gastro-intestinal tract, where infectious diseases are treatable via probiotics. In the oropharyngeal region, probiotic or replacement therapies have shown some benefit in the prevention of dental caries, otitis media, and pharyngitis, but their effect...

journal_title：Journal of dental research

authors： Teughels W,Newman MG,Coucke W,Haffajee AD,Van Der Mei HC,Haake SK,Schepers E,Cassiman JJ,Van Eldere J,van Steenberghe D,Quirynen M

更新日期：2007-11-01 00:00:00

abstract：:The major phosphoprotein in dentin is the aspartic acid and serine-rich protein called dentin phosphophoryn (DPP). DPP appears to be synthesized as a part of a larger compound protein, dentin sialophosphoprotein (DSPP). DSPP has never been isolated or detected in dentin extracts. It is now evident that DSPP is a chime...

journal_title：Journal of dental research

authors： Zhang Y,Song Y,Ravindran S,Gao Q,Huang CC,Ramachandran A,Kulkarni A,George A

更新日期：2014-02-01 00:00:00

abstract：:The objective of this study was to assess the relative effects of age and oral hygiene on the progression of periodontitis by estimating incidence from age-specific prevalence. This study analyzed data from a representative national sample of 14,690 dentate Americans, aged from 15 to 74, seen in the first National Hea...

journal_title：Journal of dental research

authors： Abdellatif HM,Burt BA

更新日期：1987-01-01 00:00:00

abstract：:The effects of different doses of p-tyramine injected i.v. and i.p. on salivary flow rates and proteins secreted by the submandibular glands of rats were studied with and without various types of autonomic blockers and two enzyme inhibitors. The salivary flow rates and the amounts of protein secreted progressively inc...

journal_title：Journal of dental research

authors： Okina A,Hidaka S,Tashiro M,Abe K

更新日期：1993-05-01 00:00:00

abstract：:During the polymerization of multifunctional monomers for dental restorations, typical final double-bond conversions range from 55 to 75%. The low conversion results in a large amount of extractable monomer, reduced adhesion to the filler, and the potential for increased swelling. In this work, the ability to increase...

journal_title：Journal of dental research

authors： Anseth KS,Goodner MD,Reil MA,Kannurpatti AR,Newman SM,Bowman CN

更新日期：1996-08-01 00:00:00

abstract：:Early detection of oral premalignant lesions (OPMLs) by visual inspection with toluidine blue has not been addressed. We conducted a community-based randomized controlled trial to assess whether using toluidine blue as an adjunctive tool for visual screening had a higher detection rate of OPMLs and could further reduc...

journal_title：Journal of dental research

authors： Su WW,Yen AM,Chiu SY,Chen TH

更新日期：2010-09-01 00:00:00

abstract：:Before the 1960s, tooth-specific caries risk was reported to be highest at 2 to 4 years after eruption. We studied the tooth-specific caries risk in three contemporary age cohorts in Finland. All together, 4072 boys and girls were followed annually from age 6 to age 18+ years in three age cohorts born in the 1960s, 19...

journal_title：Journal of dental research

authors： Härkäne T,Larmas MA,Virtanen JI,Arjas E

更新日期：2002-02-01 00:00:00

abstract：:In an attempt to make a dynamic study of the isoelectric point and the chargeability of human dental enamel, an electrochemical approach was utilized. Zeta potential of three kinds of the enamel was measured by a streaming potential method. As a result, these isoelectric points could be decided. ...

journal_title：Journal of dental research

authors： Kambara M,Asai T,Kumasaki M,Konishi K

更新日期：1978-02-01 00:00:00

abstract：:The differential diagnosis of dental wear lesions affects their clinical management. We hypothesized that surface texture parameters can differentiate simulated erosion, abrasion, and erosion-abrasion lesions on human enamel and dentin. This in vitro study comprised 2 parts (both factorial 4 × 2), with 4 lesion types ...

journal_title：Journal of dental research

authors： Hara AT,Livengood SV,Lippert F,Eckert GJ,Ungar PS

更新日期：2016-05-01 00:00:00

abstract：:Periodontitis is characterized by periodontal tissue destruction. Since interleukin-17 (IL-17) has been reported to up-regulate IL-1beta and tumor necrosis factor-alpha (TNF-alpha), it was hypothesized that it is increased in periodontitis and up-regulates these cytokines and tissue-destructive matrix metalloproteinas...

journal_title：Journal of dental research

authors： Beklen A,Ainola M,Hukkanen M,Gürgan C,Sorsa T,Konttinen YT

更新日期：2007-04-01 00:00:00

abstract：:Tooth agenesis is one of the most common developmental anomalies affecting function and esthetics. The paired-domain transcription factor, Pax9, is critical for patterning and morphogenesis of tooth and taste buds. Mutations of PAX9 have been identified in patients with tooth agenesis. Despite significant progress in ...

journal_title：Journal of dental research

authors： Wong SW,Han D,Zhang H,Liu Y,Zhang X,Miao MZ,Wang Y,Zhao N,Zeng L,Bai B,Wang YX,Liu H,Frazier-Bowers SA,Feng H

更新日期：2018-02-01 00:00:00

abstract：:Phosphatases are involved in bone and tooth mineralization, but their mechanisms of action are not completely understood. Tissue-nonspecific alkaline phosphatase (TNAP, ALPL) regulates inhibitory extracellular pyrophosphate through its pyrophosphatase activity to control mineral propagation in the matrix; mice without...

journal_title：Journal of dental research

authors： McKee MD,Yadav MC,Foster BL,Somerman MJ,Farquharson C,Millán JL

更新日期：2013-08-01 00:00:00

abstract：:The effect of chronic fluoride (F) exposure from the drinking water on parameters related to glucose homeostasis was investigated. Wistar rats were randomly distributed into 2 groups (diabetic [D] and nondiabetic [ND]; n = 54 each). In D, diabetes was induced with streptozotocin. Each group was further divided into 3 ...

journal_title：Journal of dental research

authors： Lobo JG,Leite AL,Pereira HA,Fernandes MS,Peres-Buzalaf C,Sumida DH,Rigalli A,Buzalaf MA

更新日期：2015-07-01 00:00:00

abstract：:Locally applied bisphosphonates may improve the fixation of metal implants in bone. However, systemic bisphosphonate treatment is associated with a risk of osteonecrosis of the jaw (ONJ). We hypothesized that local delivery of bisphosphonate from the implant surface improves the fixation of dental implants without com...

journal_title：Journal of dental research

authors： Abtahi J,Agholme F,Sandberg O,Aspenberg P

更新日期：2013-03-01 00:00:00

abstract：:Porcine dentin sialophosphoprotein (DSPP) is the most abundant non-collagenous protein in dentin. It is processed by proteases into 3 independent proteins: dentin sialoprotein (DSP), dentin glycoprotein (DGP), and dentin phosphoprotein (DPP). We fractionated DPP and DSP along with TGF-β activity by ion exchange (IE) c...

journal_title：Journal of dental research

authors： Yamakoshi Y,Kinoshita S,Izuhara L,Karakida T,Fukae M,Oida S

更新日期：2014-07-01 00:00:00

abstract：:Sensory, sympathetic and parasympathetic ganglia located in the head and neck of rhesus monkeys were histologically examined after injection of H3-HRP into the right mandibular premolars and molars. The results showed positive labeling of ganglionic cell bodies located in the ipsilateral trigeminal, superior cervical,...

journal_title：Journal of dental research

authors： Chiego DJ Jr,Cox CF,Avery JK

更新日期：1980-04-01 00:00:00