Abstract:
:Before the 1960s, tooth-specific caries risk was reported to be highest at 2 to 4 years after eruption. We studied the tooth-specific caries risk in three contemporary age cohorts in Finland. All together, 4072 boys and girls were followed annually from age 6 to age 18+ years in three age cohorts born in the 1960s, 1970s, and 1980s. We used a survival model and Bayesian inferential methods in the statistical analyses to establish the secular changes during this period. The analysis was based on the caries risk in individual teeth as a function of tooth age instead of summary measures, such as DMFS values. Our first finding was a marked overall decrease of caries. Moreover, analyses of the 1960 and 1970 cohorts revealed that the risk in molar teeth was highest immediately after eruption; in the youngest cohort, however, the risks of individual teeth were so low that no such dependencies on tooth age could be established.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Härkäne T,Larmas MA,Virtanen JI,Arjas Ekeywords:
subject
Has Abstractpub_date
2002-02-01 00:00:00pages
144-8issue
2eissn
0022-0345issn
1544-0591journal_volume
81pub_type
杂志文章abstract::The goal of this study was to assess the ability of a scintillation camera method to detect areas of active bone loss due to periodontitis. Technetium 99m methylene diphosphonate was used as the bone-seeking radiopharmaceutical. Bone-seeking radiopharmaceutical uptake (BSRU) was imaged and quantified in alveolar bone ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345910700010801
更新日期:1991-01-01 00:00:00
abstract::The main goal of peri-implantitis treatment is to control infection and arrest bone loss, which requires the removal of polymicrobial biofilms on the implant surface and the reduction of tissue invasion. Additionally, prognosis can be improved if reosseointegration occurs on previously contaminated implants. To evalua...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520913873
更新日期:2020-07-01 00:00:00
abstract::Conservative techniques for improving the appearance of discolored teeth have become popular in the past decade. These include: in-office bleaching with 30% hydrogen peroxide, which is applied on etched enamel with a gauze pad and then exposed to a bleaching light; home bleaching with a mild form of peroxide, such as ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720011001
更新日期:1993-01-01 00:00:00
abstract::The ability of adhesive resins to restore the physical properties of demineralized dentin has not been well-documented. The unfilled resins that are used for adhesion have relatively low moduli of elasticity and limited ability to increase dentin stiffness, although they may increase the ultimate tensile strength of d...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345950740041001
更新日期:1995-04-01 00:00:00
abstract::The purpose of this investigation was to determine the water sorption and solubility, as well as the filler composition and extent of chemical degradation in water, of eight different posterior composites. With one exception, the materials with the largest quantity of fillers had the least water sorption and solubilit...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650110601
更新日期:1986-11-01 00:00:00
abstract::Relative glycogen synthetic abilities of resting cells of fresh clinical isolates of Actinomyces viscosus and Actinomyces naeslundii originating from dental plaque samples over root surface caries lesions and non-carious sites were studied under anaerobic conditions at a constant pH of 7.0, with U-(14C)-glucose used a...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650060701
更新日期:1986-06-01 00:00:00
abstract::Protease-activated receptors (PARs) are G protein-coupled receptors, which are activated by proteolytical cleavage of the amino-terminus and act as sensors for extracellular proteases. We hypothesized that PAR-1 and PAR-2 can be modulated by inflammatory stimulus in human dental pulp cells. PAR-1 and PAR-2 gene expres...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034517719415
更新日期:2017-12-01 00:00:00
abstract::The solubilities of extracellular polysaccharide fractions produced by 14 oral streptococcal strains were compared in water, aqueous lithium and guanidine salt solutions, dimethyl sulfoxide (DMSO), and a 9:1 DMSO-water mixture. The best results for solubilizing the fractions were obtained with the DMSO-water mixture p...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345750540042601
更新日期:1975-07-01 00:00:00
abstract::Branching morphogenesis is essential for the formation of salivary glands, kidneys, lungs, and many other organs during development, but the mechanisms underlying this process are not adequately understood. Microarray and other gene expression methods have been powerful approaches for identifying candidate genes that ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034511429346
更新日期:2012-02-01 00:00:00
abstract::The aims of this work were (a) to assess the oral bioavailability of fluoride delivered from dentifrices and (b) to test for a possible link between the results and clinical data obtained with the same dentifrices. Oral fluoride concentrations were measured in samples of saliva and plaque taken from seven subjects, af...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章,评审
doi:10.1177/002203459207100S09
更新日期:1992-04-01 00:00:00
abstract::Teeth undergo postnatal organogenesis relatively late in life and only complete full maturation a few years after the crown first erupts in the oral cavity. At this stage, development can be arrested if the tooth organ is damaged by either trauma or caries. Regenerative endodontic procedures (REPs) are a treatment alt...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034517693606
更新日期:2017-06-01 00:00:00
abstract::Weanling rice rats were fed either standard laboratory chow or Diet 2000. The animals were sacrificed at 4, 8, 12, and 15 weeks. There was an increasing amount of exposed root surface and root surface caries with age in the animals fed Diet 2000. There was exposed root surface but no caries in the animals fed laborato...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560091701
更新日期:1977-09-01 00:00:00
abstract::Previously, in vitro differentiation of odontoblasts was shown for dental pulp stem cells (DPSCs) transfected with bone morphogenetic protein-2 (Bmp2). For this study, we hypothesized that such cells also show potential for mineralized tissue formation in vivo. DPSCs were transfected with Bmp2 and seeded onto a cerami...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509346258
更新日期:2009-11-01 00:00:00
abstract::Severe early childhood caries (S-ECC) is a multifactorial disease that can lead to suffering and reduced oral health-related quality of life in young children. The bacterial and fungal composition of dental plaque and how children's sex is associated with S-ECC are largely unknown. In this study, V4-16S rRNA and ITS1 ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520908595
更新日期:2020-06-01 00:00:00
abstract::Bilateral resections of the superficial masseter, posterior temporal, and anterior digastric muscles of rats were done to determine their effects on mandibular growth. The macroscopic findings support the functional matrix theory of mandibular growth. The analysis of body weight and the statistical two-way analysis of...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550052301
更新日期:1976-09-01 00:00:00
abstract::Early-onset periodontitis (EOP) is considered to have a genetic basis which has not been clearly defined. Genetic polymorphisms of the vitamin D receptor (VDR-B-b) and the immunoglobulin-Fc-gamma receptor IIIb (FcgammaRIIIb-NA1-NA2) are associated with bone metabolism and infectious diseases, respectively. The purpose...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345010800120501
更新日期:2001-12-01 00:00:00
abstract::We evaluated the histopathological response of the periodontal membrane to intentionally-replanted teeth carrying composite (experimental) and silver amalgam (control) restorations in the middle third of each root. The study revealed that the amalgam produced, in the periodontal tissues, an initial localized inflammat...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620011801
更新日期:1983-01-01 00:00:00
abstract::Masticatory muscle silent periods were compared in normal subjects and in patients with MPD syndrome before and after a variety of psychological, physiological, and pharmacological forms of therapy. All patients initially showed prolonged silent periods in one or more of the muscles. There was a direct relationship be...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600030501
更新日期:1981-03-01 00:00:00
abstract::Schoolchildren residing in a fluoride-deficient area were provided either a sodium fluoride (0.1% F) or a nonfluoride dentifrice for home use. About half the children provided each type of dentifrice were also given an initial prophylaxis. Combining the data with regard to the type of dentifrice indicated that the sod...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/00220345750540013601
更新日期:1975-01-01 00:00:00
abstract::Investigators have used chemotherapeutic agents topically for plaque control without knowing the drug concentration necessary to inhibit the growth of odontopathic microorganisms. S mutans, S sanguis, A viscosus and A naeslundii are important components of the plaque flora. The minimal inhibitory concentrations (MIC) ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550040401
更新日期:1976-07-01 00:00:00
abstract::Since 1935, various mechanisms have been suggested for the formation of subsurface lesions and, in particular, the surface layer covering enamel lesions. The relatively intact mineral-rich and porous surface layer is most likely caused by kinetic events. The suggested mineral-rich outer layer in sound enamel, the orga...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345860650010201
更新日期:1986-01-01 00:00:00
abstract::This study investigated the relevance between pulp vitality and autophagy in aged human dental pulp cells (HDPCs) and whether peroxisome proliferator-activated receptor gamma (PPARγ) affects autophagy regulation for homeostasis in the aging progress. In vivo experiments were used in human and Sprague-Dawley rat teeth ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515573833
更新日期:2015-05-01 00:00:00
abstract::Two independent cross-over studies investigated the possibility of enhanced early enamel lesion remineralization with the use of chewing gum. The first study involved a sorbitol-containing chewing gum, and the second, which had an identical protocol, tested a sucrose-containing chewing gum. In each study, 12 volunteer...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/00220345920710120801
更新日期:1992-12-01 00:00:00
abstract::Stable fluoride-resistant mutants of Streptococcus mutans GS-5 were isolated on Todd-Hewitt agar by a step-wise selection procedure. Resistance is defined here as the ability to form colonies in 48 hr. First-step mutants demonstrated six different levels of resistance, ranging from 400 to 1000 micrograms/mL sodium flu...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660101701
更新日期:1987-10-01 00:00:00
abstract::Loss of hybrid layer integrity compromises resin-dentin bond stability. Matrix metalloproteinases (MMPs) may be partially responsible for hybrid layer degradation. Since chlorhexidine inhibits MMPs, we hypothesized that chlorhexidine would decelerate the loss of resin-dentin bonds. Class I preparations in extracted th...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/154405910708600115
更新日期:2007-01-01 00:00:00
abstract::The effects of various additives on the setting of the glass-ionomer cement system was studied by means of cone and plate viscometry. The action of (+)-tartaric acid, the most important additive, on the setting reaction depended on its concentration. Low concentrations accelerated the development of viscosity of the c...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670120101
更新日期:1988-12-01 00:00:00
abstract::Gingival epithelium is a site of active trafficking of Langerhans cells (LCs), while the lamina propria in chronic periodontitis (CP) contains CD83+ mature dendritic cells (mDCs) and CD4+ T-cells. The immune cells that contribute to the mDCs, and whether mDCs engage with T-cells in situ, are unclear. Using several imm...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200915
更新日期:2003-09-01 00:00:00
abstract::Pieces of fresh rat incisor enamel were extracted with various buffer solutions and prepared for electron microscopy. I observed partial or complete removal of organic constituents, shrinkage of rods and interrods, separation of stippled material from the enamel, and partial decalcification. The results modify the con...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:1982-12-01 00:00:00
abstract::Adenoviral vectors effectively transfer genes to rat salivary glands. However, potent immune responses limit their use in vivo. Mice offer more opportunities than rats for the study of these immune processes. We first established conditions for infection of mouse salivary glands, with an adenoviral vector. The effects...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790020201
更新日期:2000-02-01 00:00:00
abstract::PAX9 is a transcription factor expressed in the tooth mesenchyme during tooth morphogenesis. In Pax9-null mice, tooth development is arrested at the bud stage. In humans, heterozygous mutations in PAX9 have been associated with non-syndromic tooth agenesis, predominantly in the molars. Here, we report 2 novel mutation...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513519801
更新日期:2014-03-01 00:00:00