Applying modern survival analysis methods to longitudinal dental caries studies.

Abstract:

:Before the 1960s, tooth-specific caries risk was reported to be highest at 2 to 4 years after eruption. We studied the tooth-specific caries risk in three contemporary age cohorts in Finland. All together, 4072 boys and girls were followed annually from age 6 to age 18+ years in three age cohorts born in the 1960s, 1970s, and 1980s. We used a survival model and Bayesian inferential methods in the statistical analyses to establish the secular changes during this period. The analysis was based on the caries risk in individual teeth as a function of tooth age instead of summary measures, such as DMFS values. Our first finding was a marked overall decrease of caries. Moreover, analyses of the 1960 and 1970 cohorts revealed that the risk in molar teeth was highest immediately after eruption; in the youngest cohort, however, the risks of individual teeth were so low that no such dependencies on tooth age could be established.

journal_name

J Dent Res

authors

Härkäne T,Larmas MA,Virtanen JI,Arjas E

keywords:

subject

Has Abstract

pub_date

2002-02-01 00:00:00

pages

144-8

issue

2

eissn

0022-0345

issn

1544-0591

journal_volume

81

pub_type

杂志文章
  • Detection of periodontal disease activity with a scintillation camera.

    abstract::The goal of this study was to assess the ability of a scintillation camera method to detect areas of active bone loss due to periodontitis. Technetium 99m methylene diphosphonate was used as the bone-seeking radiopharmaceutical. Bone-seeking radiopharmaceutical uptake (BSRU) was imaged and quantified in alveolar bone ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345910700010801

    authors: Reddy MS,English R,Jeffcoat MK,Tumeh SS,Williams RC

    更新日期:1991-01-01 00:00:00

  • Graphene Oxide Enables the Reosteogenesis of Previously Contaminated Titanium In Vitro.

    abstract::The main goal of peri-implantitis treatment is to control infection and arrest bone loss, which requires the removal of polymicrobial biofilms on the implant surface and the reduction of tissue invasion. Additionally, prognosis can be improved if reosseointegration occurs on previously contaminated implants. To evalua...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034520913873

    authors: Qin W,Wang C,Jiang C,Sun J,Yu C,Jiao T

    更新日期:2020-07-01 00:00:00

  • The effects of etching, micro-abrasion, and bleaching on surface enamel.

    abstract::Conservative techniques for improving the appearance of discolored teeth have become popular in the past decade. These include: in-office bleaching with 30% hydrogen peroxide, which is applied on etched enamel with a gauze pad and then exposed to a bleaching light; home bleaching with a mild form of peroxide, such as ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345930720011001

    authors: Tong LS,Pang MK,Mok NY,King NM,Wei SH

    更新日期:1993-01-01 00:00:00

  • Tensile properties of resin-infiltrated demineralized human dentin.

    abstract::The ability of adhesive resins to restore the physical properties of demineralized dentin has not been well-documented. The unfilled resins that are used for adhesion have relatively low moduli of elasticity and limited ability to increase dentin stiffness, although they may increase the ultimate tensile strength of d...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345950740041001

    authors: Sano H,Takatsu T,Ciucchi B,Russell CM,Pashley DH

    更新日期:1995-04-01 00:00:00

  • Water sorption and filler characteristics of composites for use in posterior teeth.

    abstract::The purpose of this investigation was to determine the water sorption and solubility, as well as the filler composition and extent of chemical degradation in water, of eight different posterior composites. With one exception, the materials with the largest quantity of fillers had the least water sorption and solubilit...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345860650110601

    authors: Oysaed H,Ruyter IE

    更新日期:1986-11-01 00:00:00

  • Glycogen synthetic abilities of Actinomyces viscosus and Actinomyces naeslundii freshly isolated from dental plaque over root surface caries lesions and non-carious sites.

    abstract::Relative glycogen synthetic abilities of resting cells of fresh clinical isolates of Actinomyces viscosus and Actinomyces naeslundii originating from dental plaque samples over root surface caries lesions and non-carious sites were studied under anaerobic conditions at a constant pH of 7.0, with U-(14C)-glucose used a...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345860650060701

    authors: Komiyama K,Khandelwal RL,Duncan DE

    更新日期:1986-06-01 00:00:00

  • PAR-1 and PAR-2 Expression Is Enhanced in Inflamed Odontoblast Cells.

    abstract::Protease-activated receptors (PARs) are G protein-coupled receptors, which are activated by proteolytical cleavage of the amino-terminus and act as sensors for extracellular proteases. We hypothesized that PAR-1 and PAR-2 can be modulated by inflammatory stimulus in human dental pulp cells. PAR-1 and PAR-2 gene expres...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034517719415

    authors: Alvarez MMP,Moura GE,Machado MFM,Viana GM,de Souza Costa CA,Tjäderhane L,Nader HB,Tersariol ILS,Nascimento FD

    更新日期:2017-12-01 00:00:00

  • Investigation of possible solvents for extracellular polysaccharides from Streptococcus mutans and Streptococcus sanguis.

    abstract::The solubilities of extracellular polysaccharide fractions produced by 14 oral streptococcal strains were compared in water, aqueous lithium and guanidine salt solutions, dimethyl sulfoxide (DMSO), and a 9:1 DMSO-water mixture. The best results for solubilizing the fractions were obtained with the DMSO-water mixture p...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345750540042601

    authors: Lamberts BL,Meyer TS,Simonson LG

    更新日期:1975-07-01 00:00:00

  • Viral gene transfer to developing mouse salivary glands.

    abstract::Branching morphogenesis is essential for the formation of salivary glands, kidneys, lungs, and many other organs during development, but the mechanisms underlying this process are not adequately understood. Microarray and other gene expression methods have been powerful approaches for identifying candidate genes that ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034511429346

    authors: Hsu JC,Di Pasquale G,Harunaga JS,Onodera T,Hoffman MP,Chiorini JA,Yamada KM

    更新日期:2012-02-01 00:00:00

  • Oral fluoride measurements for estimation of the anti-caries efficacy of fluoride treatments.

    abstract::The aims of this work were (a) to assess the oral bioavailability of fluoride delivered from dentifrices and (b) to test for a possible link between the results and clinical data obtained with the same dentifrices. Oral fluoride concentrations were measured in samples of saliva and plaque taken from seven subjects, af...

    journal_title:Journal of dental research

    pub_type: 临床试验,杂志文章,评审

    doi:10.1177/002203459207100S09

    authors: Duckworth RM,Morgan SN,Gilbert RJ

    更新日期:1992-04-01 00:00:00

  • Decellularized Human Dental Pulp as a Scaffold for Regenerative Endodontics.

    abstract::Teeth undergo postnatal organogenesis relatively late in life and only complete full maturation a few years after the crown first erupts in the oral cavity. At this stage, development can be arrested if the tooth organ is damaged by either trauma or caries. Regenerative endodontic procedures (REPs) are a treatment alt...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034517693606

    authors: Song JS,Takimoto K,Jeon M,Vadakekalam J,Ruparel NB,Diogenes A

    更新日期:2017-06-01 00:00:00

  • Root surface caries in the molar teeth of rice rats. II. Quantitation of lesions induced by high sucrose diet.

    abstract::Weanling rice rats were fed either standard laboratory chow or Diet 2000. The animals were sacrificed at 4, 8, 12, and 15 weeks. There was an increasing amount of exposed root surface and root surface caries with age in the animals fed Diet 2000. There was exposed root surface but no caries in the animals fed laborato...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345770560091701

    authors: Doff RS,Rosen S,App G

    更新日期:1977-09-01 00:00:00

  • Mineralized tissue formation by BMP2-transfected pulp stem cells.

    abstract::Previously, in vitro differentiation of odontoblasts was shown for dental pulp stem cells (DPSCs) transfected with bone morphogenetic protein-2 (Bmp2). For this study, we hypothesized that such cells also show potential for mineralized tissue formation in vivo. DPSCs were transfected with Bmp2 and seeded onto a cerami...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034509346258

    authors: Yang X,van der Kraan PM,Bian Z,Fan M,Walboomers XF,Jansen JA

    更新日期:2009-11-01 00:00:00

  • Sex-Based Diverse Plaque Microbiota in Children with Severe Caries.

    abstract::Severe early childhood caries (S-ECC) is a multifactorial disease that can lead to suffering and reduced oral health-related quality of life in young children. The bacterial and fungal composition of dental plaque and how children's sex is associated with S-ECC are largely unknown. In this study, V4-16S rRNA and ITS1 ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034520908595

    authors: de Jesus VC,Shikder R,Oryniak D,Mann K,Alamri A,Mittermuller B,Duan K,Hu P,Schroth RJ,Chelikani P

    更新日期:2020-06-01 00:00:00

  • Comparative anatomic study of mandibular growth in rats after bilateral resections of superficial masseter, posterior temporal, and anterior digastric muscles.

    abstract::Bilateral resections of the superficial masseter, posterior temporal, and anterior digastric muscles of rats were done to determine their effects on mandibular growth. The macroscopic findings support the functional matrix theory of mandibular growth. The analysis of body weight and the statistical two-way analysis of...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345760550052301

    authors: Lifshitz J

    更新日期:1976-09-01 00:00:00

  • Analysis of vitamin D and Fcgamma receptor polymorphisms in Japanese patients with generalized early-onset periodontitis.

    abstract::Early-onset periodontitis (EOP) is considered to have a genetic basis which has not been clearly defined. Genetic polymorphisms of the vitamin D receptor (VDR-B-b) and the immunoglobulin-Fc-gamma receptor IIIb (FcgammaRIIIb-NA1-NA2) are associated with bone metabolism and infectious diseases, respectively. The purpose...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345010800120501

    authors: Yoshihara A,Sugita N,Yamamoto K,Kobayashi T,Miyazaki H,Yoshi H

    更新日期:2001-12-01 00:00:00

  • Effects of composite restorations on the periodontal membrane in monkeys.

    abstract::We evaluated the histopathological response of the periodontal membrane to intentionally-replanted teeth carrying composite (experimental) and silver amalgam (control) restorations in the middle third of each root. The study revealed that the amalgam produced, in the periodontal tissues, an initial localized inflammat...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345830620011801

    authors: Nasjleti CE,Castelli WA,Caffesse RG

    更新日期:1983-01-01 00:00:00

  • Masticatory muscle silent periods in patients with MPD syndrome before and after treatment.

    abstract::Masticatory muscle silent periods were compared in normal subjects and in patients with MPD syndrome before and after a variety of psychological, physiological, and pharmacological forms of therapy. All patients initially showed prolonged silent periods in one or more of the muscles. There was a direct relationship be...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345810600030501

    authors: Skiba TJ,Laskin DM

    更新日期:1981-03-01 00:00:00

  • Influence of an experimental sodium fluoride dentifrice on dental caries incidence in children.

    abstract::Schoolchildren residing in a fluoride-deficient area were provided either a sodium fluoride (0.1% F) or a nonfluoride dentifrice for home use. About half the children provided each type of dentifrice were also given an initial prophylaxis. Combining the data with regard to the type of dentifrice indicated that the sod...

    journal_title:Journal of dental research

    pub_type: 临床试验,杂志文章

    doi:10.1177/00220345750540013601

    authors: Stookey GK,Beiswanger BB

    更新日期:1975-01-01 00:00:00

  • Susceptibility of some plaque microorganisms to chemotherapeutic agents.

    abstract::Investigators have used chemotherapeutic agents topically for plaque control without knowing the drug concentration necessary to inhibit the growth of odontopathic microorganisms. S mutans, S sanguis, A viscosus and A naeslundii are important components of the plaque flora. The minimal inhibitory concentrations (MIC) ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345760550040401

    authors: Newbrun E,Felton RA,Bulkacz J

    更新日期:1976-07-01 00:00:00

  • The nature of early caries lesions in enamel.

    abstract::Since 1935, various mechanisms have been suggested for the formation of subsurface lesions and, in particular, the surface layer covering enamel lesions. The relatively intact mineral-rich and porous surface layer is most likely caused by kinetic events. The suggested mineral-rich outer layer in sound enamel, the orga...

    journal_title:Journal of dental research

    pub_type: 杂志文章,评审

    doi:10.1177/00220345860650010201

    authors: Arends J,Christoffersen J

    更新日期:1986-01-01 00:00:00

  • PPARγ Maintains Homeostasis through Autophagy Regulation in Dental Pulp.

    abstract::This study investigated the relevance between pulp vitality and autophagy in aged human dental pulp cells (HDPCs) and whether peroxisome proliferator-activated receptor gamma (PPARγ) affects autophagy regulation for homeostasis in the aging progress. In vivo experiments were used in human and Sprague-Dawley rat teeth ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034515573833

    authors: Lee YH,Lee HY,Kim TG,Lee NH,Yu MK,Yi HK

    更新日期:2015-05-01 00:00:00

  • The effect of chewing gum use on in situ enamel lesion remineralization.

    abstract::Two independent cross-over studies investigated the possibility of enhanced early enamel lesion remineralization with the use of chewing gum. The first study involved a sorbitol-containing chewing gum, and the second, which had an identical protocol, tested a sucrose-containing chewing gum. In each study, 12 volunteer...

    journal_title:Journal of dental research

    pub_type: 临床试验,杂志文章

    doi:10.1177/00220345920710120801

    authors: Creanor SL,Strang R,Gilmour WH,Foye RH,Brown J,Geddes DA,Hall AF

    更新日期:1992-12-01 00:00:00

  • Effects of pH on expression of sodium fluoride resistance in Streptococcus mutans.

    abstract::Stable fluoride-resistant mutants of Streptococcus mutans GS-5 were isolated on Todd-Hewitt agar by a step-wise selection procedure. Resistance is defined here as the ability to form colonies in 48 hr. First-step mutants demonstrated six different levels of resistance, ranging from 400 to 1000 micrograms/mL sodium flu...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345870660101701

    authors: Brussock SM,Kral TA

    更新日期:1987-10-01 00:00:00

  • Chlorhexidine preserves dentin bond in vitro.

    abstract::Loss of hybrid layer integrity compromises resin-dentin bond stability. Matrix metalloproteinases (MMPs) may be partially responsible for hybrid layer degradation. Since chlorhexidine inhibits MMPs, we hypothesized that chlorhexidine would decelerate the loss of resin-dentin bonds. Class I preparations in extracted th...

    journal_title:Journal of dental research

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/154405910708600115

    authors: Carrilho MR,Carvalho RM,de Goes MF,di Hipólito V,Geraldeli S,Tay FR,Pashley DH,Tjäderhane L

    更新日期:2007-01-01 00:00:00

  • A rheological study of the role of additives on the setting of glass-ionomer cements.

    abstract::The effects of various additives on the setting of the glass-ionomer cement system was studied by means of cone and plate viscometry. The action of (+)-tartaric acid, the most important additive, on the setting reaction depended on its concentration. Low concentrations accelerated the development of viscosity of the c...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345880670120101

    authors: Hill RG,Wilson AD

    更新日期:1988-12-01 00:00:00

  • Multiple dendritic cell (DC) subpopulations in human gingiva and association of mature DCs with CD4+ T-cells in situ.

    abstract::Gingival epithelium is a site of active trafficking of Langerhans cells (LCs), while the lamina propria in chronic periodontitis (CP) contains CD83+ mature dendritic cells (mDCs) and CD4+ T-cells. The immune cells that contribute to the mDCs, and whether mDCs engage with T-cells in situ, are unclear. Using several imm...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910308200915

    authors: Jotwani R,Cutler CW

    更新日期:2003-09-01 00:00:00

  • Fine structure of extracted rat incisor enamel.

    abstract::Pieces of fresh rat incisor enamel were extracted with various buffer solutions and prepared for electron microscopy. I observed partial or complete removal of organic constituents, shrinkage of rods and interrods, separation of stippled material from the enamel, and partial decalcification. The results modify the con...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:

    authors: Kallenbach E

    更新日期:1982-12-01 00:00:00

  • Adenoviral-mediated gene transfer to mouse salivary glands.

    abstract::Adenoviral vectors effectively transfer genes to rat salivary glands. However, potent immune responses limit their use in vivo. Mice offer more opportunities than rats for the study of these immune processes. We first established conditions for infection of mouse salivary glands, with an adenoviral vector. The effects...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345000790020201

    authors: Wang S,Baum BJ,Yamano S,Mankani MH,Sun D,Jonsson M,Davis C,Graham FL,Gauldie J,Atkinson JC

    更新日期:2000-02-01 00:00:00

  • Novel PAX9 mutations cause non-syndromic tooth agenesis.

    abstract::PAX9 is a transcription factor expressed in the tooth mesenchyme during tooth morphogenesis. In Pax9-null mice, tooth development is arrested at the bud stage. In humans, heterozygous mutations in PAX9 have been associated with non-syndromic tooth agenesis, predominantly in the molars. Here, we report 2 novel mutation...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034513519801

    authors: Mitsui SN,Yasue A,Masuda K,Watanabe K,Horiuchi S,Imoto I,Tanaka E

    更新日期:2014-03-01 00:00:00