Influence of an experimental sodium fluoride dentifrice on dental caries incidence in children.

abstract：:Extracellular vesicles (EVs), several tens to hundreds of nanometers in size, are vesicles secreted by cells for intercellular communication. EVs released from mesenchymal stem cells (MSC-EVs) have the potential to treat multiple diseases. This study aimed to determine the effects of MSC-EVs on bisphosphonate-related ...

journal_title：Journal of dental research

authors： Watanabe J,Sakai K,Urata Y,Toyama N,Nakamichi E,Hibi H

更新日期：2020-05-01 00:00:00

abstract：:This 24-mo randomized controlled trial was based on a double-blind parallel design, and it compared the effectiveness of 2 fluoride application protocols in arresting dentine caries in primary teeth. Three-year-old children with active dentine caries were recruited and randomly allocated to 2 treatment groups. Childre...

journal_title：Journal of dental research

authors： Chen KJ,Gao SS,Duangthip D,Lo ECM,Chu CH

更新日期：2021-01-01 00:00:00

abstract：:Epstein-Barr virus (EBV), in addition to its transforming properties, contributes to the pathogenesis of several inflammatory diseases. Here, we investigated its involvement in oral lichen planus (OLP), a common autoimmune-like disease of unknown etiopathogenesis that can display a malignant potential. EBV-infected ce...

journal_title：Journal of dental research

authors： Raybaud H,Olivieri CV,Lupi-Pegurier L,Pagnotta S,Marsault R,Cardot-Leccia N,Doglio A

更新日期：2018-12-01 00:00:00

abstract：:Retinoic acid-inducible gene I (RIG-I) is a cytosolic pattern recognition receptor involved in the sensing of RNA viruses and the initiation of antiviral responses. Fusobacterium nucleatum, a Gram-negative anaerobic bacterium associated with periodontal disease, is capable of invading cells. We hypothesized that F. nu...

journal_title：Journal of dental research

authors： Lee P,Tan KS

更新日期：2014-02-01 00:00:00

abstract：:The synchronized cyrstal dissolution hypothesis previously proposed to explain the unusual dissolution behavior of human dental enamel and hydroxyapatite in partially saturated acidic media has been critically examined with dissolution-dialysis transport experiments. The findings are in accord with the hypothesis. A m...

journal_title：Journal of dental research

authors： Fawzi MB,Sonobe T,Higuchi WI,Hefferren JJ

更新日期：1977-04-01 00:00:00

abstract：:Seven ATCC strains of bacteria were examined for apatite formation in a chemically-defined calcification-supporting medium and also in a metastable calcium phosphate solution. One, E. coli, calcified in both. One, S. aureus, calcified in the solution, but not in the medium. The other five did not calcify in either. Th...

journal_title：Journal of dental research

authors： Ennever J,Streckfuss JL,Goldschmidt MC

更新日期：1981-10-01 00:00:00

abstract：:Histone deacetylases (HDACs) are important regulators of gene expression that are aberrantly regulated in several inflammatory and infectious diseases. HDAC inhibitors (HDACi) suppress inflammatory activation of various cell types through epigenetic and non-epigenetic mechanisms, and ameliorate pathology in a mouse mo...

journal_title：Journal of dental research

authors： Lagosz KB,Bysiek A,Macina JM,Bereta GP,Kantorowicz M,Lipska W,Sochalska M,Gawron K,Kaczmarzyk T,Chomyszyn-Gajewska M,Fossati G,Potempa J,Grabiec AM

更新日期：2020-01-01 00:00:00

abstract：:Acculturation is a complex phenomenon that can serve as a proxy for cultural norms and behaviors affecting care-seeking, prevention behaviors, and, ultimately, health outcomes. The purpose of this study was to assess the effect of acculturation on the oral health of Haitian immigrants in New York City. We hypothesized...

journal_title：Journal of dental research

authors： Cruz GD,Shore R,Le Geros RZ,Tavares M

更新日期：2004-02-01 00:00:00

abstract：:The histopathologic status of gingival tissue was assessed according to the criteria of Page and Schroeder.(5) Rhodamine-labeled bacteria were used to assess the antigenic specificity of plasma cells in the tissue. Examination of tissue sections revealed that 31.6% of plasma cells in the advanced lesions bound the lab...

journal_title：Journal of dental research

authors： Kagan JM

更新日期：1980-11-01 00:00:00

abstract：:Setting reactions and compressive strengths of a self-hardening calcium phosphate cement (CPC) were investigated. The CPC consists of tetracalcium phosphate (TTCP) and anhydrous dicalcium phosphate (DCPA). The cement specimens were prepared by mixing 0.7 g of the powder (TTCP 72.9 wt% + DCPA 27.1 wt%) with 0.175 mL of...

journal_title：Journal of dental research

authors： Fukase Y,Eanes ED,Takagi S,Chow LC,Brown WE

更新日期：1990-12-01 00:00:00

abstract：:Smoking has been established as an important risk factor for periodontal disease and tooth loss. The purpose of this study was a prospective evaluation of the effects of smoking on dental care utilization and its costs, based on data from 5712 males aged 20-59 yrs. Age, dental health behavior, and history of diabetes ...

journal_title：Journal of dental research

authors： Ide R,Hoshuyama T,Wilson D,Takahashi K,Higashi T

更新日期：2009-01-01 00:00:00

abstract：:Investigators have used chemotherapeutic agents topically for plaque control without knowing the drug concentration necessary to inhibit the growth of odontopathic microorganisms. S mutans, S sanguis, A viscosus and A naeslundii are important components of the plaque flora. The minimal inhibitory concentrations (MIC) ...

journal_title：Journal of dental research

authors： Newbrun E,Felton RA,Bulkacz J

更新日期：1976-07-01 00:00:00

abstract：:The discovery of the phenomenon "osseointegration," or functional ankylosis, has led to the development of oral implants with high clinical performance. Consequently, the placement of titanium implants has changed the paradigms of restorative dentistry. Implants are used to prevent placing reconstructions anchored on ...

journal_title：Journal of dental research

authors： Lang NP

更新日期：2019-11-01 00:00:00

abstract：:The effect of combined administration of chlorhexidine and fluoride in the drinking water of hamsters on plaque and caries prevention was studied. Plaque indices of the hamsters receiving chlorhexidine either alone or simultaneously with fluoride were significantly lower than those of the control and fluoride only tre...

journal_title：Journal of dental research

authors： Brayer L,Gedalia I,Gover A

更新日期：1977-11-01 00:00:00

abstract：:Insulin resistance is one of the critical pathogeneses of type 2 diabetes mellitus (T2DM). Elevated levels of plasma branched-chain amino acids (BCAAs) are associated with insulin resistance. Recent studies have demonstrated the role of Porphyromonas gingivalis in the development of insulin resistance. However, the me...

journal_title：Journal of dental research

authors： Tian J,Liu C,Zheng X,Jia X,Peng X,Yang R,Zhou X,Xu X

更新日期：2020-07-01 00:00:00

abstract：:Understanding the mechanical properties of human teeth is important to clinical tooth preparation and to the development of "tooth-like" restorative materials. Previous studies have focused on the macroscopic fracture behavior of enamel and dentin. In the present study, we performed indentation studies to understand t...

journal_title：Journal of dental research

authors： Xu HH,Smith DT,Jahanmir S,Romberg E,Kelly JR,Thompson VP,Rekow ED

更新日期：1998-03-01 00:00:00

abstract：:The antimicrobial and cariostatic activities of the dihydrochloride and dihydrofluoride salts of alexidine (1,6-bis-[2-ethylhexylbiguanido]hexane) were compared to those of chlorhexidine acetate and sodium fluoride in rats implanted orally with Streptococcus mutans 6715 and fed a cariogenic diet. Experimental caries w...

journal_title：Journal of dental research

authors： Curtis SN,Dooley CL

更新日期：1979-04-01 00:00:00

abstract：:The filtration and diffusion of tritiated water through dentin disks were measured ina split-chamber diffusion cell. The dentin had been cut with a diamond disk and the surfaces modified with a carbide fissure bur or diamond bur. Disks were given a secondary burnishing treatment with a blank bur or a modified blank bu...

journal_title：Journal of dental research

authors： Boyer DB,Svare CW

更新日期：1981-06-01 00:00:00

abstract：:The present investigation demonstrates that direct application of a composite resin on an acid-etched, vital dentin surface is hazardous to the pulp in monkey teeth. This indicates that exposed dentin should be protected before treating the tooth with a restorative technique including acid etching. A ca(OH)2-containin...

journal_title：Journal of dental research

authors： Eriksen HM

更新日期：1976-03-01 00:00:00

abstract：:Disks of dentin taken from extracted human teeth demonstrated the optical property of the magnification/reduction effect. When images were transmitted from a pulpal-to-occlusal direction, the images were magnified. When the disks were inverted, the images were reduced in size. The images were slightly distorted but cl...

journal_title：Journal of dental research

authors： Walton RE,Outhwaite WC,Pashley DF

更新日期：1976-07-01 00:00:00

abstract：:The purpose of this investigation was to examine the inhibitory effects of aqueous extracts derived from the bark-containing sticks (Neem stick) of Azadirachta indica upon bacterial aggregation, growth, adhesion to hydroxyapatite, and production of insoluble glucan, which may affect in vitro plaque formation. Neem sti...

journal_title：Journal of dental research

authors： Wolinsky LE,Mania S,Nachnani S,Ling S

更新日期：1996-02-01 00:00:00

abstract：:Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large...

journal_title：Journal of dental research

authors： Yamada S,Ozaki N,Tsushima K,Yamaba S,Fujihara C,Awata T,Sakashita H,Kajikawa T,Kitagaki J,Yamashita M,Yanagita M,Murakami S

更新日期：2016-08-01 00:00:00

abstract：:Periodontitis is a chronic inflammatory disease affecting oral tissues. The continuous, high production of cytokines by host cells triggered by periodontopathogens is thought to be responsible for the destruction of tooth-supporting tissues. Macrophages play a critical role in this host inflammatory response to period...

journal_title：Journal of dental research

authors： Bodet C,Chandad F,Grenier D

更新日期：2006-03-01 00:00:00

abstract：:This case-control study evaluated the association of headache and other co-morbid pain with temporomandibular disorder (TMD) pain in adolescents and explored the temporal co-variance of headache and TMD pain. In a population-based sample of 12- to 19-year-olds, 350 patients with self-reported TMD pain and 350 healthy ...

journal_title：Journal of dental research

authors： Nilsson IM,List T,Drangsholt M

更新日期：2013-09-01 00:00:00

abstract：:Temporomandibular joint (TMJ) disorders, including degenerative TMJ disease, occur primarily in women of reproductive age. Previous studies showed elevated estrogen levels in subjects with TMJ disorders relative to controls and the presence of estrogen receptors α and β (ERα and ERβ) in TMJ fibrocartilage. Additionall...

journal_title：Journal of dental research

authors： Ahmad N,Chen S,Wang W,Kapila S

更新日期：2018-08-01 00:00:00

abstract：:As a major intracellular degradation and recycling machinery, autophagy plays an important role in maintaining cellular homeostasis and remodeling during normal development. Our previous study showed that fluorapatite (FA) crystal-coated electrospun polycaprolactone (PCL) was capable of inducing differentiation and mi...

journal_title：Journal of dental research

authors： Li Y,Guo T,Zhang Z,Yao Y,Chang S,Nör JE,Clarkson BH,Ni L,Liu J

更新日期：2016-06-01 00:00:00

abstract：:Pilocarpine (P) is of potential utility in the treatment of xerostomia. Because optimal development of P dosage forms for humans requires that its pharmacokinetics and pharmacodynamics be defined, this intravenous study of its disposition and associated salivary responses was performed. In a hospital setting, two heal...

journal_title：Journal of dental research

authors： Tanzer JM,Kramer PA,Schulman P,Willard AK

更新日期：1995-12-01 00:00:00

abstract：:Primary cilia regulate several developmental processes and mediate hedgehog signaling. To study their roles in cranial base development, we created conditional mouse mutants deficient in Polaris, a critical primary cilium component, in cartilage. Mutant post-natal cranial bases were deformed, and their synchondrosis g...

journal_title：Journal of dental research

authors： Ochiai T,Nagayama M,Nakamura T,Morrison T,Pilchak D,Kondo N,Hasegawa H,Song B,Serra R,Pacifici M,Koyama E

更新日期：2009-06-01 00:00:00

abstract：:We explored the potential to diagnose Zika virus (ZIKV) infection by analyzing peptides in saliva during a convalescent phase of infection, long after resolution of acute disease. A 25-y-old woman clinically diagnosed with Zika fever in the first trimester was enrolled with her dizygotic twins for a 3-mo postnatal sam...

journal_title：Journal of dental research

authors： Zuanazzi D,Arts EJ,Jorge PK,Mulyar Y,Gibson R,Xiao Y,Bringel Dos Santos M,Machado MAAM,Siqueira WL

更新日期：2017-09-01 00:00:00

abstract：:Cellular hypoxia may be a useful indication of tissue distress in the dental pulp that could be used to investigate the early stages of pulpal responses. Tritiated misonidazole (3H-MISO) is a marker which preferentially labels cells with decreased oxygen tension (hypoxia). The experiments reported here were carried ou...

journal_title：Journal of dental research

authors： Baumgardner KR,Walton RE,Osborne JW,Born JL

更新日期：1996-10-01 00:00:00