Abstract:
:The filtration and diffusion of tritiated water through dentin disks were measured ina split-chamber diffusion cell. The dentin had been cut with a diamond disk and the surfaces modified with a carbide fissure bur or diamond bur. Disks were given a secondary burnishing treatment with a blank bur or a modified blank bur. Burnishing reduced the permeability of dentin cut with a fissure bur.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Boyer DB,Svare CWdoi
10.1177/00220345810600061101subject
Has Abstractpub_date
1981-06-01 00:00:00pages
966-71issue
6eissn
0022-0345issn
1544-0591journal_volume
60pub_type
杂志文章abstract::Despite the recognized link between aging and cancer, most preclinical studies in experimental tumor models are conducted with 6- to 8-wk-old rodents. The goal of the present study was to examine the impact of age on tumor incidence, growth, and microenvironmental characteristics in mouse models of head and neck squam...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034518775736
更新日期:2018-10-01 00:00:00
abstract::Mark Twain provides a humorous and insightful look into the origins of periodontal therapy and anesthesia in "Happy Memories of the Dental Chair". The main character of this story is Dr. John Riggs, the father of periodontics. Dr. Horace Wells, a pioneer in the field of anesthesia, also appears in the story. Twain pre...
journal_title:Journal of dental research
pub_type: 传,历史文章,杂志文章
doi:10.1177/0022034510366677
更新日期:2010-07-01 00:00:00
abstract::Mastication as a mild but life-long exercise has been examined as a possibility for maintaining brain function in the elderly. Little is known, however, about the cerebral circulatory response during masticatory movement. The aim of this study was to develop a monitoring system for circulation dynamics during masticat...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510383692
更新日期:2011-01-01 00:00:00
abstract::In previous studies, human dental pulp stem cells (hDPSCs) were mainly isolated from adults. In this present study, we characterized hDPSCs isolated from an earlier developmental stage to evaluate the potential usage of these cells for tissue-regenerative therapy. hDPSCs isolated at the crown-completed stage showed a ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700716
更新日期:2008-07-01 00:00:00
abstract::In this study, we first investigated the expressions of Jagged1, Notch2, the receptor activator of nuclear factor-kappa B ligand (RANKL), and interleukin (IL)-6 in areas of root resorption during experimental tooth movement in rats in vivo. We then assessed the effects of compression force (CF) with or without GSI (an...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514555364
更新日期:2015-01-01 00:00:00
abstract::Pulpal blood flow was determined in 32 dogs ranging in age from 6 weeks to 18 months by the isotope fractionation method incorporating diffusible and nondiffusible tracers. Dogs were placed into selected age groups by the developmental status of the canine teeth. For the teeth sampled, the maxillary first, second, and...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560102601
更新日期:1977-10-01 00:00:00
abstract::Dickkopf-related protein 1 (DKK1) is a potent inhibitor of Wnt/β-catenin signaling. Dkk1-null mutant embryos display severe defects in head induction. Conversely, targeted expression of Dkk1 in dental epithelial cells leads to the formation of dysfunctional enamel knots and subsequent tooth defects during embryonic de...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034511421926
更新日期:2011-11-01 00:00:00
abstract::The periodontal ligament (PDL) works as a suspensory ligament when external mechanical stress is placed on the teeth. PDL fibroblasts, the principal cells in the PDL, are responsible for many PDL functions. We hypothesized that mechanosensitive ion channels are present in human PDL fibroblasts, which are capable of re...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500716
更新日期:2006-07-01 00:00:00
abstract::Decisions to replace existing restorations are often based on clinical findings of margin discrepancies and other restoration defects. Previous studies have suggested that such findings do not correlate well with the actual presence of secondary caries, and that treatment should be deferred until caries is clinically ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720121301
更新日期:1993-12-01 00:00:00
abstract::An analysis of the relationship between creep and microstructural characteristics of several gamma2-containing amalgams showed the grain size of the Ag-Hg phase (gamma1) to be a predominant factor influencing creep. When gamma1 grain size is increased, creep is reduced. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560121401
更新日期:1977-12-01 00:00:00
abstract::Non-steroidal anti-inflammatory drugs (NSAIDs) are used to manage pain and inflammatory disorders. We hypothesized that gingival fibroblasts actively accumulate NSAIDs and enhance their levels in gingival connective tissue. Using fluorescence to monitor NSAID transport, we demonstrated that cultured gingival fibroblas...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500511
更新日期:2006-05-01 00:00:00
abstract::Fluorides are present in the environment. Excessive systemic exposure to fluorides can lead to disturbances of bone homeostasis (skeletal fluorosis) and enamel development (dental/enamel fluorosis). The severity of dental fluorosis is also dependent upon fluoride dose and the timing and duration of fluoride exposure. ...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034510384626
更新日期:2011-05-01 00:00:00
abstract::Porcine dentin sialophosphoprotein (DSPP) is the most abundant non-collagenous protein in dentin. It is processed by proteases into 3 independent proteins: dentin sialoprotein (DSP), dentin glycoprotein (DGP), and dentin phosphoprotein (DPP). We fractionated DPP and DSP along with TGF-β activity by ion exchange (IE) c...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514534690
更新日期:2014-07-01 00:00:00
abstract::The destabilizing effect of endodontic treatment upon teeth is still controversial. The purpose of this study was to investigate the effects of different steps of endodontic treatments upon the rigidity of teeth. Extracted untreated central maxillary anterior teeth were loaded (3.75 N), and deformations of the root we...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500416
更新日期:2006-04-01 00:00:00
abstract::The human mandibular condyle has a parasagittal plate-like trabecular structure. We tested the hypothesis that this structure reflects the mechanical loading of the condyle. We developed a finite element model of the condyle to analyze the strains occurring during static compressive loading. The principal strains in t...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910208101010
更新日期:2002-10-01 00:00:00
abstract::During the past two decades, some major pitfalls in fluorine analysis have been recognized and overcome. Therefore, it is important that facts be separated from fallacies in published literature on levels and forms of fluorine (ionic, bound, covalent, etc.) in biological materials, in order that correct perceptions of...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345900690S105
更新日期:1990-02-01 00:00:00
abstract::Few studies have investigated smoking as a risk factor for root canal treatment. We studied the effect of smoking on the incidence of root canal treatment, controlling for recognized risk factors, in 811 dentate male participants in the VA Dental Longitudinal Study. Participants were not VA patients. Follow-up ranged ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500406
更新日期:2006-04-01 00:00:00
abstract::The following five outlines are the results to date of the Workshop held in Rockville, Maryland, in January, 1990. The topics considered in these outlines are: (1) validation of immunological and/or nucleic acid identification probes, (2) cross-calibration of methods and/or laboratories for multi-laboratory cooperativ...
journal_title:Journal of dental research
pub_type: 指南,杂志文章
doi:10.1177/00220345910700031401
更新日期:1991-03-01 00:00:00
abstract::Diet is recognized as one of the most important factors affecting the equilibrium of the oral bacterial flora. Studies related to dental caries development have focused mainly on the effect of carbohydrates. In the present work, using swabbing coupled with an immuno-colony-blot assay, we followed the indigenous oral b...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345900690030801
更新日期:1990-03-01 00:00:00
abstract::Elemental analysis of two precious alloyceramic systems revealed the accumulation of Sn atoms within the interaction zone of couples subjected to a range of metal oxidation time; and varying total firing times. The source of Sn atoms which accumulated within the interaction zone was the opaque porcelain layer which co...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560090301
更新日期:1977-09-01 00:00:00
abstract::The relative contribution of the matrix of dentin to the physical properties of dentin is unknown but thought to be small. The objective of this study was to test the hypothesis that the demineralized matrix of dentin contributes little to the strength of dentin by measuring and comparing the ultimate tensile strength...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345940730061201
更新日期:1994-06-01 00:00:00
abstract::Urinary catecholamines have been used to measure emotionally stressful states which may affect the development of dental caries. This study investigates the hypothesis that children with and without dental caries do not differ significantly in the mean values of urinary catecholamines such as epinephrine, norepinephri...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345950740100801
更新日期:1995-10-01 00:00:00
abstract::Autoimmune responses to heat-shock protein 60 (HSP60) contribute to the progression of atherosclerosis, whereas immunization with HSP60 may induce atheroprotective responses. We assessed the capacity of an atheroprotective vaccine that targeted a recombinant HSP60 from Porphyromonas gingivalis (rGroEL) to induce a pro...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514523784
更新日期:2014-04-01 00:00:00
abstract::Ammoniacal silver stain showed that there was a decrease in nucleohistones in zinc-deficient rat buccal hyperplastic epithelium as compared to control. Autoradiographic study showed that there was decreased incorporation of 3H-arginine and 3H-lysine in the hyperplastic epithelium. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560122501
更新日期:1977-12-01 00:00:00
abstract::Hemifacial microsomia (HFM) is a congenital disorder marked by facial asymmetry. Whether facial asymmetry accounts for asymmetrical dental development is unknown. There are few data on dental development relative to mandibular development or severity of HFM, or on development over time. We hypothesized that when mandi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510378425
更新日期:2010-12-01 00:00:00
abstract::Vascular endothelial growth factor (VEGF) is a potent inducer of angiogenesis, vascular permeability, and edema. Up-regulation of VEGF expression in the dental pulp may result in increased intra-pulpal pressure, and contribute to pain and irreversible tissue damage. Lipoteichoic acid (LTA) is an amphiphilic molecule f...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200612
更新日期:2003-06-01 00:00:00
abstract::Significant differences exist between human and Macaca fascicularis patterns of mandibular movement during mastication. Macaque patterns display less asymmetry, more uniformity, and limited lateral excursions when compared to humans for mastication of the same food. Different anatomical structures between the two spec...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345780570071301
更新日期:1978-07-01 00:00:00
abstract::The expired air of a group of 48 persons, 40 with and eight without dental amalgam restorations, was analyzed for its mercury content before and after chewing. Expired air samples were collected in polyethylene bags, and a known quantity of each was pumped into the mercury detector for measurement. The results showed ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600090601
更新日期:1981-09-01 00:00:00
abstract::The aim of this study was to assess the changes occurring in subgingival biofilm composition and in the periodontal clinical parameters of subjects with periodontitis and type 2 diabetes mellitus (DM) treated by means of scaling and root planing (SRP) only or combined with systemic metronidazole (MTZ) and amoxicillin ...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/0022034516639274
更新日期:2016-07-01 00:00:00
abstract::Mucous membrane pemphigoid or cicatricial pemphigoid is a mucocutaneous blistering disease characterized by autoantibodies to different molecules in the basement membrane zone. Our objectives were to identify the target antigen recognized by sera from 20 untreated patients with pemphigoid disease limited to the oral c...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345010800080601
更新日期:2001-08-01 00:00:00